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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPS10 Gene

protein-coding   GIFtS: 64
GCID: GC06M035236

Ribosomal Protein S10

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein S101 2
DBA92 5
40S Ribosomal Protein S102
S102

External Ids:    HGNC: 103831   Entrez Gene: 62042   Ensembl: ENSG000001246147   OMIM: 6036325   UniProtKB: P467833   

Export aliases for RPS10 gene to outside databases

Previous GC identifers: GC06M034383 GC06M034432 GC06M034493 GC06M034107 GC06M034514 GC06M034898


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPS10 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family
of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers
compared to adjacent normal tissues has been observed, although no correlation between the level of expression
and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are
multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple
transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between
this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif
3).(provided by RefSeq, Feb 2011)

GeneCards Summary for RPS10 Gene: 
RPS10 (ribosomal protein S10) is a protein-coding gene. Diseases associated with RPS10 include rps10-related diamond-blackfan anemia, and diamond-blackfan anemia, and among its related super-pathways are Eukaryotic Translation Initiation and Formation of the ternary complex, and subsequently, the 43S complex. GO annotations related to this gene include protein binding. An important paralog of this gene is RPS10-NUDT3.

UniProtKB/Swiss-Prot: RS10_HUMAN, P46783
Function: Component of the 40S ribosomal subunit

Gene Wiki entry for RPS10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPS10 gene promoter:
         SREBP-1c   Olf-1   GATA-1   SREBP-1b   Evi-1   AREB6   CREB   SREBP-1a   deltaCREB   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPS10 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPS10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPS10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

RPS10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPS10 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M035236:  view genomic region     (about GC identifiers)

Start:
34,385,231 bp from pter      End:
34,393,902 bp from pter
Size:
8,672 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RS10_HUMAN, P46783 (See protein sequence)
Recommended Name: 40S ribosomal protein S10  
Size: 165 amino acids; 18898 Da
Subunit: Component of the small ribosomal subunit. Interacts with PRMT5. The methylated form interacts with NPM1
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Localized in the granular component (GC) region of the
nucleolus. Methylation is required for its localization in the GC region. Co-localizes with NPS1 in the GC region
of the nucleolus
1 PDB 3D structure from and Proteopedia for RPS10:
3J3A (3D)    
Secondary accessions: B2R4E3 Q5TZC0

Explore the universe of human proteins at neXtProt for RPS10: NX_P46783

Explore proteomics data for RPS10 at MOPED 

Post-translational modifications:

  • UniProtKB: Methylated by PRMT5. Methylation is necessary for its interaction with NPS1, its localization in the granular
    component (GC) region of the nucleolus, for the proper assembly of ribosomes, protein synthesis and optimal cell
    proliferation
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P46783

  • RPS10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPS10 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001005.1  NP_001190174.1  NP_001191020.1  

    ENSEMBL proteins: 
     ENSP00000363169   ENSP00000347271  
    Reactome Protein details: P46783
    Human Recombinant Protein Products for RPS10: 
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    Cloud-Clone Corp. Proteins for RPS10 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome NAS7772601
    GO:0022627cytosolic small ribosomal subunit IDA15883184

    RPS10 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPS: S ribosomal proteins

    1 InterPro protein domain:
     IPR005326 S10_plectin_N

    Graphical View of Domain Structure for InterPro Entry P46783

    ProtoNet protein and cluster: P46783

    1 Blocks protein domain: IPB005326 Plectin/S10

    UniProtKB/Swiss-Prot: RS10_HUMAN, P46783
    Similarity: Belongs to the ribosomal protein S10e family


    RPS10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RS10_HUMAN, P46783
    Function: Component of the 40S ribosomal subunit

         Genatlas biochemistry entry for RPS10:
    40S ribosomal protein S10

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    RPS10 for ontologies           About GeneDecksing


    Phenotypes:
         6 GenomeRNAi human phenotypes for RPS10:
     Cytoplasmic 40S maturation def  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability of wild-ty 
     Increased gamma-H2AX phosphory  Nucleolar pre-40S maturation d 

    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPS10 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate RPS10:
    hsa-miR-4272
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPS10 About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    3' -UTR-mediated translational regulation0.93
    Influenza Infection0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2Translation initiation complex formation
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.95
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    Ribosomal scanning and start codon recognition0.95
    Translation initiation complex formation0.87
    3Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92
    4Generic Transcription Pathway
    Gene Expression0.47
    5Asparagine N-linked glycosylation
    Metabolism of proteins0.35

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPS10
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPS10
        Cytoplasmic Ribosomal Proteins

    5/27        Reactome Pathways for RPS10 (see all 27)
        Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane


    1         Kegg Pathway  (Kegg details for RPS10):
        Ribosome


    RPS10 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPS10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/362 Interacting proteins for RPS10 (P467832, 3 ENSP000003472714) via UniProtKB, MINT, STRING, and/or I2D (see all 362)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPS10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPS10 (RS10)

    Search CenterWatch for drugs/clinical trials and news about RPS10 / RS10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPS10 gene (3 alternative transcripts): 
    NM_001014.4  NM_001203245.2  NM_001204091.1  

    Unigene Clusters for RPS10:

    Ribosomal protein S10
    Hs.406620  [show with all ESTs], Hs.645317  [show with all ESTs]
    Unigene Representative Sequences: AK025353, BF570090
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000344700 ENST00000464218 ENST00000467531 ENST00000494077(uc003ojm.3)
    ENST00000326199(uc003ojn.3 uc021yyu.1) ENST00000480942
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate RPS10:
    hsa-miR-4272
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    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 3): RPS10 (NM_001014)
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPS10
      Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPS10

    Additional mRNA sequence: 

    AB209165.1 AK311797.1 BC001032.2 BC070235.1 BC071946.1 BC073799.1 U14972.1 

    24/86 DOTS entries (see all 86):

    DT.100741961  DT.95148488  DT.102845466  DT.100060228  DT.100741966  DT.87009604  DT.100741994  DT.100060233 
    DT.100742007  DT.100851413  DT.97861563  DT.100741977  DT.97863460  DT.97863822  DT.100741970  DT.91727229 
    DT.97863804  DT.100874268  DT.97862802  DT.100741964  DT.91894836  DT.121358906  DT.100741997  DT.91780040 

    1 AceView cDNA sequence:

    BC073799 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPS10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTCTCTCA
    RPS10 Expression
    About this image


    See RPS10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPS10

    SOURCE GeneReport for Unigene clusters: Hs.406620 Hs.645317
        SABiosciences Custom PCR Arrays for RPS10
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPS10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPS10 gene from 9/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rps105 ribosomal protein S10   --   17 (14.59 cM) 27630422 
    chicken
    (Gallus gallus)
    Aves --
    --
    99(a)
    possible ortholog
    26(4318556-4324043)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC055985.12   -- 80.63(n)    BC055985.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc659362 ribosomal protein S10 78.54(n)   394121  BC055098.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG142063
    RpS10b1
    structural constituent of ribosome3
    Ribosomal protein S10b1
    65(a)
    (best of 2)3
    63.03(n)1
    65.38(a)1
      18D33
    329531  NM_134480.31  NP_608324.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rps-101 , 3 40S ribosomal protein S103
    Protein RPS-101
    48(a)3
    61.49(n)1
    54.73(a)1
      I(4583936-4584795)3
    1720611  NM_058997.31  NP_491398.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPS10A(YOR293W)4 Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10 less   --   15(867098-867852) 854468  NP_014936.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G415201 40S ribosomal protein S10-2 58.33(n)
    53.21(a)
      834154  NM_123516.3  NP_198967.1 
    rice
    (Oryza sativa)
    Liliopsida Os.201822 Transcribed sequence with weak similarity to protein refNP_198967.1 (A.thaliana) putative protein [Arabidopsis thaliana] less 72.92(n)    AU174824.1 


    ENSEMBL Gene Tree for RPS10 (if available)
    TreeFam Gene Tree for RPS10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPS10 gene
    RPS10-NUDT32  
    2 SIMAP similar genes for RPS10 using alignment to 2 protein entries:     RS10_HUMAN (see all proteins):
    RPS10P5    PLEC

    RPS10 for paralogs           About GeneDecksing


    5/35 Pseudogenes.org Pseudogenes for RPS10 (see all 35)
    PGOHUM00000238646 PGOHUM00000242221 PGOHUM00000239764 PGOHUM00000249948 PGOHUM00000247139


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/290 SNPs in RPS10 are shown (see all 290)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs346909511,2
    C--34110101(+) TTTTT-/TGAGAC 3 -- int12Minor allele frequency- T:0.00NA CSA 4
    rs3739913301,2
    C--34111924(+) CTTCG-/CCCCCC 3 -- int10--------
    rs1462779991,2
    --34111926(+) CGACCA/CCCCCC 3 -- int10--------
    rs2009521911,2
    C--34111926(+) GACCC-/ACCCCC 3 -- int10--------
    rs1390337681,2
    --34111927(+) GACCCC/GCCCCC 3 -- int10--------
    rs1433602441,2
    C--34111928(+) ACCCCA/CCCCCT 3 -- int10--------
    rs1155509111,2
    C,F--34299919(+) TGAGCC/ATTGAA 3 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1436185981,2
    --34299958(+) ACCATG/TCCTGT 3 -- ds50010--------
    rs1465097121,2
    --34299975(+) TCTCCA/GTAAAT 3 -- ds50010--------
    rs168897061,2
    C,F,H--34299980(+) ATAAAT/CTGAAG 3 -- ds500124Minor allele frequency- C:0.21NA NS EA CSA WA 2901

    HapMap Linkage Disequilibrium report for RPS10 (34385231 - 34393902 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RPS10:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv1938e1CNV Complex17122850


    Human Gene Mutation Database (HGMD): RPS10
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RPS10
    DNA2.0 Custom Variant and Variant Library Synthesis for RPS10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603632   
    OMIM disorders: 613308  
    UniProtKB/Swiss-Prot: RS10_HUMAN, P46783
  • Diamond-Blackfan anemia 9 (DBA9) [MIM:613308]: A form of Diamond-Blackfan anemia, a congenital
    non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is
    characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.
    30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most
    frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • 13 diseases for RPS10:    About MalaCards
    rps10-related diamond-blackfan anemia    diamond-blackfan anemia    macrocytic anemia    colorectal cancer
    pituitary tumors    anemia    short stature    cleft palate
    influenza    systemic lupus erythematosus    lupus erythematosus    schizophrenia
    hepatocellular carcinoma

    1 disease from the University of Copenhagen DISEASES database for RPS10:
    Diamond-Blackfan anemia

    RPS10 for disorders           About GeneDecksing


    Export disorders for RPS10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPS10 gene, integrated from 9 sources (see all 70):
    (articles sorted by number of sources associating them with RPS10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (1998)
    2. Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs. (PubMed id 7772601)1, 2, 3 Frigerio J.-M.... Iovanna J.L. (1995)
    3. Methylation of ribosomal protein S10 by protein-argin ine methyltransferase 5 regulates ribosome biogenesis. (PubMed id 20159986)1, 2, 9 Ren J....Xu Z. (2010)
    4. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. (PubMed id 20116044)1, 2 Doherty L....Gazda H.T. (2010)
    5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)1, 2 Vladimirov S.N.... Otto A. (1996)
    8. Pituitary tumor-transforming gene protein associates with ribosomal protein S10 and a novel human homologue of DnaJ in testicular cells. (PubMed id 9915854)1, 9 Pei L. (1999)
    9. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    10. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6204 HGNC: 10383 AceView: RPS10.2 Ensembl:ENSG00000124614 euGenes: HUgn6204
    ECgene: RPS10 Kegg: 6204 H-InvDB: RPS10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPS10 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPS10 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPS10 gene:
    Search GeneIP for patents involving RPS10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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