Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RPRD2 Gene

protein-coding   GIFtS: 51
GCID: GC01P150335

Regulation Of Nuclear Pre-MRNA Domain Containing 2

(Previous name: KIAA0460)
(Previous symbol: KIAA0460)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Regulation Of Nuclear Pre-MRNA Domain Containing 21 2
KIAA04601 2 3
Regulation Of Nuclear Pre-MRNA Domain-Containing Protein 22

External Ids:    HGNC: 290391   Entrez Gene: 232482   Ensembl: ENSG000001631257   OMIM: 6146955   UniProtKB: Q5VT523   

Export aliases for RPRD2 gene to outside databases

Previous GC identifers: GC01P148604 GC01P121715


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for RPRD2 Gene:
RPRD2 (regulation of nuclear pre-mRNA domain containing 2) is a protein-coding gene. An important paralog of this gene is RPRD1B.

Gene Wiki entry for RPRD2 (KIAA0460) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPRD2 gene promoter:
         HOXA9B   HOXA9   SRF   SRF (504 AA)   Meis-1b   YY1   c-Rel   E2F-1   E2F   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPRD2 promoter sequence
   Search Chromatin IP Primers for RPRD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPRD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.2

RPRD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPRD2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P150335:  view genomic region     (about GC identifiers)

Start:
150,335,567 bp from pter      End:
150,449,042 bp from pter
Size:
113,476 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RPRD2_HUMAN, Q5VT52 (See protein sequence)
Recommended Name: Regulation of nuclear pre-mRNA domain-containing protein 2  
Size: 1461 amino acids; 156020 Da
Subunit: Associates with the RNA polymerase II complex
Sequence caution: Sequence=AAF28922.1; Type=Erroneous initiation; Sequence=AAH45623.2; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for RPRD2:
4FLB (3D)    
Secondary accessions: A8K6N8 B3KPT1 B4E2Q6 O75048 Q5VT51 Q5VT53 Q6MZL4 Q86XD2 Q9P0D7
Alternative splicing: 5 isoforms:  Q5VT52-1   Q5VT52-2   Q5VT52-3   Q5VT52-4   Q5VT52-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPRD2: NX_Q5VT52

Explore proteomics data for RPRD2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys293
  • Modification sites at PhosphoSitePlus

  • See RPRD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056018.2  
    ENSEMBL proteins: 
     ENSP00000383785   ENSP00000358063   ENSP00000358064   ENSP00000445482  

    RPRD2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for RPRD2
    GenScript Custom Purified and Recombinant Proteins Services for RPRD2
    Novus Biologicals RPRD2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPRD2

     
    Search eBioscience for Proteins for RPRD2 

     
    Search antibodies-online for proteins for RPRD2 

     
    antibodies-online peptides for RPRD2

    RPRD2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RPRD2
    Novus Biologicals RPRD2 Antibodies
    Abcam antibodies for RPRD2
    Cloud-Clone Corp. Antibodies for RPRD2
    ThermoFisher Antibodies for RPRD2
    antibodies-online antibodies for RPRD2 (10 products) 

    RPRD2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RPRD2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPRD2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RPRD2
    Cloud-Clone Corp. CLIAs for RPRD2
    Search eBioscience for ELISAs for RPRD2 
    antibodies-online kits for RPRD2 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR006903 RNA_pol_II-bd
     IPR006569 CID_dom
     IPR008942 ENTH_VHS

    Graphical View of Domain Structure for InterPro Entry Q5VT52

    ProtoNet protein and cluster: Q5VT52

    1 Blocks protein domain: IPB006569 Regulation of nuclear pre-mRNA protein

    UniProtKB/Swiss-Prot: RPRD2_HUMAN, Q5VT52
    Similarity: Contains 1 CID domain


    Find genes that share domains with RPRD2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPRD2

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPRD2:
    hsa-mir-296-3p (MIRT038455), hsa-mir-24-3p (MIRT050369), hsa-mir-1 (MIRT024055), hsa-mir-320a (MIRT044769), hsa-mir-26b-5p (MIRT030338), hsa-mir-769-5p (MIRT039187), hsa-mir-16-5p (MIRT032044), hsa-let-7e-5p (MIRT051632)

    Block miRNA regulation of human, mouse, rat RPRD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RPRD2 (see all 68):
    hsa-miR-1321 hsa-miR-607 hsa-miR-15a hsa-miR-4305 hsa-miR-30d hsa-miR-219-5p hsa-miR-519a hsa-miR-3162-5p
    SwitchGear 3'UTR luciferase reporter plasmidRPRD2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RPRD2
    Predesigned siRNA for gene silencing in human, mouse, rat RPRD2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RPRD2

    Clone
    Products:
         
    OriGene clones in human, mouse for RPRD2 (see all 13)
    OriGene ORF clones in mouse, rat for RPRD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPRD2 (NM_015203)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPRD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPRD2
    Addgene plasmids for RPRD2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RPRD2
    Browse ESI BIO Cell Lines and PureStem Progenitors for RPRD2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPRD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016591DNA-directed RNA polymerase II, holoenzyme IDA--

    Find genes that share ontologies with RPRD2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPRD2
    Interactions:

        Search GeneGlobe Interaction Network for RPRD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPRD2 (Q5VT522, 3 ENSP000003580644) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WWOXQ9NZC72, 3, ENSP000003861614MINT-72777 I2D: score=3 STRING: ENSP00000386161
    UPF1Q929003, ENSP000002628034I2D: score=2 STRING: ENSP00000262803
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    MAP4K4O958193I2D: score=1 
    XRN2ENSP000003663964STRING: ENSP00000366396
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPRD2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RPRD2 gene: 
    NM_015203.3  

    Unigene Cluster for RPRD2:

    Regulation of nuclear pre-mRNA domain containing 2
    Hs.213666  [show with all ESTs]
    Unigene Representative Sequence: NM_015203
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000492220 ENST00000401000(uc010pcc.1 uc009wlr.3 uc001eup.4)
    ENST00000369067 ENST00000369068 ENST00000539519
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RPRD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RPRD2 (see all 68):
    hsa-miR-1321 hsa-miR-607 hsa-miR-15a hsa-miR-4305 hsa-miR-30d hsa-miR-219-5p hsa-miR-519a hsa-miR-3162-5p
    SwitchGear 3'UTR luciferase reporter plasmidRPRD2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RPRD2
    Predesigned siRNA for gene silencing in human, mouse, rat RPRD2
    Clone
    Products:
         
    OriGene clones in human, mouse for RPRD2 (see all 13)
    OriGene ORF clones in mouse, rat for RPRD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPRD2 (NM_015203)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPRD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPRD2
    Addgene plasmids for RPRD2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RPRD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPRD2
      QuantiTect SYBR Green Assays in human, mouse, rat RPRD2
      QuantiFast Probe-based Assays in human, mouse, rat RPRD2

    Additional mRNA sequence: 

    AB007929.2 AF161362.1 AK022984.1 AK026120.1 AK056707.1 AK125864.1 AK291703.1 AK304380.1 
    AK308148.1 BC045623.1 BX641025.1 

    15 DOTS entries:

    DT.413298  DT.100818240  DT.213352  DT.100651833  DT.121404582  DT.102829594  DT.40221328  DT.100807449 
    DT.100818243  DT.75193037  DT.95086891  DT.100022887  DT.121404607  DT.40221269  DT.91746474 

    Selected AceView cDNA sequences (see all 248):

    R80633 H88537 AK056707 BX099295 AI358242 F28811 BM725312 BU552454 
    BU685478 AI039251 AI096441 AL579182 AK026120 BM460686 AW593888 BM677746 
    BM763639 CA389803 BF477907 BF115587 AI569785 BG117328 BQ638395 H15436 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RPRD2 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:        -     -     -     -           -                 -           -     -                                                   
    SP2:                    -     -     -     -                 -           -                                                         
    SP3:                    -     -     -     -                 -           -     -                                                   
    SP4:                    -     -     -     -                                                                                       
    SP5:                          -     -     -                                                                                       


    ECgene alternative splicing isoforms for RPRD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RPRD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGGAGGAGG
    RPRD2 Expression
    About this image

    RPRD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPRD2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.213666
        Custom PCR Arrays for RPRD2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RPRD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPRD2
    QuantiTect SYBR Green Assays in human, mouse, rat RPRD2
    QuantiFast Probe-based Assays in human, mouse, rat RPRD2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPRD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RPRD2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rprd21 , 5 regulation of nuclear pre-mRNA domain containing 21, 5 90.24(n)1
    91.22(a)1
      3 (41.00 cM)5
    751371  NM_001081293.11  NP_001074762.11 
     957598735 
    chicken
    (Gallus gallus)
    Aves RPRD21 regulation of nuclear pre-mRNA domain containing 2 71.69(n)
    74.89(a)
      425074  NM_001012932.2  NP_001012950.2 
    lizard
    (Anolis carolinensis)
    Reptilia RPRD26
    regulation of nuclear pre-mRNA domain containing 2...
    68(a)
    1 ↔ 1
    GL343802.1(84699-104349)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX845340.12   -- 78.93(n)    BX845340.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufk52b122 wufk52b12 74.12(n)   334701  BC056830.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG151606
    --
    27(a)
    1 ↔ 1
    2L(18590897-18595431)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RTT1036
    Protein that interacts with exonuclease Rat1p and ...
    21(a)
    1 → many
    IV(1038280-1039509) YDR289C


    ENSEMBL Gene Tree for RPRD2 (if available)
    TreeFam Gene Tree for RPRD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RPRD2 gene
    RPRD1B2  RPRD1A2  

    Find genes that share paralogs with RPRD2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for RPRD2 (see all 2386)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs8287841,2
    C,F,A--150335240(-) gcagcT/Acaagt 1 -- us2k19Minor allele frequency- A:0.48NA WA CSA EA 369
    rs1839730771,2
    --150335250(+) CTGAGA/GCAGGA 1 -- us2k10--------
    rs1379766341,2
    --150335389(+) GTTCCA/GCTCCC 1 -- us2k10--------
    rs1900919801,2
    --150335394(+) GCTCCC/TCGTCT 1 -- us2k10--------
    rs354577291,2
    C--150335396(+) TCCCC-/GTCTCG 1 -- us2k12Minor allele frequency- G:0.00NA CSA 4
    rs774804581,2
    --150335396(+) TCCCCC/GTCTCG 1 -- us2k10--------
    rs1930725911,2
    --150335453(+) TCTTTC/GGAGAA 1 -- us2k10--------
    rs1448061321,2
    C--150335489(+) TTCTTA/GTACTG 1 -- us2k10--------
    rs115762891,2
    C,F,H--150335534(+) cgcacA/Gcacac 1 -- us2k12Minor allele frequency- G:0.24NA 126
    rs115762931,2
    C,F,H--150335536(+) cacacA/Gcacac 1 -- us2k12Minor allele frequency- G:0.25NA 124

    HapMap Linkage Disequilibrium report for RPRD2 (150335567 - 150449042 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RPRD2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658303CNV Deletion23128226
    esv2540817CNV Deletion19546169
    esv2717773CNV Deletion23290073
    esv2717784CNV Deletion23290073
    esv2670951CNV Deletion23128226
    esv989789CNV Deletion20482838
    esv2717795CNV Deletion23290073
    esv999047CNV Insertion20482838
    nsv831548CNV Loss17160897
    nsv872416CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPRD2
    DNA2.0 Custom Variant and Variant Library Synthesis for RPRD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 614695    OMIM disorders: --


    Find genes that share disorders with RPRD2           About GenesLikeMe

    Genetic Association Database (GAD): RPRD2

    Export disorders for RPRD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RPRD2 gene, integrated from 10 sources (see all 32):
    (articles sorted by number of sources associating them with RPRD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. (PubMed id 22231121)1, 2, 3 Ni Z.... Greenblatt J.F. (Transcription 2011)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    8. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)1, 2 Seki N.... Ohara O. (DNA Res. 1997)
    9. Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins. (PubMed id 23537643)1 Liang C....Zhang L. (Biochem. Biophys. Res. Commun. 2013)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 23248 HGNC: 29039 AceView: KIAA0460 Ensembl:ENSG00000163125 euGenes: HUgn23248
    ECgene: RPRD2 H-InvDB: RPRD2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0460

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RPRD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RPRD2 gene:
    Search GeneIP for patents involving RPRD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RPRD2  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RPRD2  
     OriGene qSTAR qPCR primer pairs in human, mouse for RPRD2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RPRD2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPRD2   OriGene Custom Protein Services for RPRD2  

     
     
     Block miRNA regulation of human, mouse, rat RPRD2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RPRD2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPRD2 Predesigned siRNA for gene silencing in human, mouse, rat RPRD2
     QuantiFast Probe-based Assays in human, mouse, rat RPRD2 QuantiTect SYBR Green Assays in human, mouse, rat RPRD2
     Custom PCR Arrays for RPRD2 Search Chromatin IP Primers for RPRD2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPRD2  Search GeneGlobe Interaction Network for RPRD2
     Regulatory tfbs in RPRD2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for RPRD2 GenScript cDNA clones with any tag delivered in your preferred vector for RPRD2
     GenScript Custom Assay Services for RPRD2 GenScript Custom overexpressing Cell Line Services for RPRD2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RPRD2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RPRD2 antibodies
     RPRD2 lysates
     Antibodies for RPRD2
     See all of Abcam's Antibodies, Kits and Proteins for RPRD2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RPRD2
     Antibodies for RPRD2
     ELISAs for RPRD2
     CLIAs for RPRD2



     Browse ESI BIO Cell Lines and PureStem Progenitors for RPRD2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPRD2
     SwitchGear 3'UTR luciferase reporter plasmids for RPRD2
     SwitchGear Promoter luciferase reporter plasmids for RPRD2
     ThermoFisher Antibodies for RPRD2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPRD2
     Browse compounds at ApexBio
     Addgene plasmids for RPRD2
      Search eBioscience for proteins for RPRD2
      Search eBioscience for elisas for RPRD2
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for RPRD2
     antibodies-online antibodies for RPRD2 (10 products)
     antibodies-online kits for RPRD2 (4 products)
     antibodies-online peptides for RPRD2
      Search antibodies-online for proteins for RPRD2
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RPRD2 gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4