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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPRD1B Gene

protein-coding   GIFtS: 52
GCID: GC20P036662

Regulation Of Nuclear Pre-MRNA Domain Containing 1B

(Previous name: chromosome 20 open reading frame 77)
(Previous symbol: C20orf77)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Regulation Of Nuclear Pre-MRNA Domain Containing 1B1 2     NET602
C20orf771 2 3     Cell-Cycle Related And Expression-Elevated Protein In Tumor2
Cell Cycle-Related And Expression-Elevated Protein In Tumor2 3     dJ1057B20.22
CREPT2 3     Regulation Of Nuclear Pre-MRNA Domain-Containing Protein 1B2
Chromosome 20 Open Reading Frame 771     

External Ids:    HGNC: 162091   Entrez Gene: 584902   Ensembl: ENSG000001014137   OMIM: 6146945   UniProtKB: Q9NQG53   

Export aliases for RPRD1B gene to outside databases

Previous GC identifers: GC20P036096 GC20P033397


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RPRD1B Gene: 
RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) is a protein-coding gene. Diseases associated with RPRD1B include cercarial dermatitis, and gnathomiasis. GO annotations related to this gene include protein binding and RNA polymerase II core binding. An important paralog of this gene is RPRD1A.

UniProtKB/Swiss-Prot: RPR1B_HUMAN, Q9NQG5
Function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase
II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances
expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region
before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading
through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of
the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes
including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011362.10  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPRD1B gene promoter:
         GR   E2F   E2F-1   GR-beta   Sox9   GR-alpha   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPRD1B promoter sequence
   Search SABiosciences Chromatin IP Primers for RPRD1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPRD1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21-q12   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.21-q12

RPRD1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPRD1B gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P036662:  view genomic region     (about GC identifiers)

Start:
36,661,948 bp from pter      End:
36,720,768 bp from pter
Size:
58,821 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RPR1B_HUMAN, Q9NQG5 (See protein sequence)
Recommended Name: Regulation of nuclear pre-mRNA domain-containing protein 1B  
Size: 326 amino acids; 36900 Da
Subunit: Associates with the RNA polymerase II complex
Subcellular location: Nucleus
Sequence caution: Sequence=AAH01696.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
3 PDB 3D structures from and Proteopedia for RPRD1B:
4FLA (3D)        4FU3 (3D)        4HFG (3D)    
Secondary accessions: Q1WDE7 Q6PKF4

Explore the universe of human proteins at neXtProt for RPRD1B: NX_Q9NQG5

Explore proteomics data for RPRD1B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NQG5

  • RPRD1B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPRD1B Protein Expression
    REFSEQ proteins: NP_067038.1  
    ENSEMBL proteins: 
     ENSP00000362532   ENSP00000436816   ENSP00000433947   ENSP00000416420  

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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0016591DNA-directed RNA polymerase II, holoenzyme IDA--

    RPRD1B for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR006903 RNA_pol_II-bd
     IPR006569 CID_dom
     IPR008942 ENTH_VHS

    Graphical View of Domain Structure for InterPro Entry Q9NQG5

    ProtoNet protein and cluster: Q9NQG5

    1 Blocks protein domain: IPB006569 Regulation of nuclear pre-mRNA protein

    UniProtKB/Swiss-Prot: RPR1B_HUMAN, Q9NQG5
    Similarity: Belongs to the UPF0400 (RTT103) family
    Similarity: Contains 1 CID domain


    RPRD1B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPR1B_HUMAN, Q9NQG5
    Function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase
    II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances
    expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region
    before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading
    through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of
    the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes
    including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000993RNA polymerase II core binding IDA--
    GO:0005515protein binding IPI--
         
    RPRD1B for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPRD1B:
     Increased G2M DNA content, inc  Increased cell number in G1, s 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rprd1b):
     behavior/neurological  hematopoietic system  homeostasis/metabolism 

    RPRD1B for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidRPRD1B 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPRD1B

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for RPRD1B (Q9NQG51, 2, 3 ENSP000003625324) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TUBGCP4Q9UGJ12, 3, ENSP000002603834MINT-67164 I2D: score=4 STRING: ENSP00000260383
    POLR2AP249281, ENSP000003149494EBI-747925,EBI-295301 STRING: ENSP00000314949
    CCND1ENSP000002275074STRING: ENSP00000227507
    TERF2ENSP000002549424STRING: ENSP00000254942
    --Q9BVR63I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0008284positive regulation of cell proliferation IDA--
    GO:0010564regulation of cell cycle process IDA--
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IDA--
    GO:0070940dephosphorylation of RNA polymerase II C-terminal domain IMP--

    RPRD1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPRD1B (RPR1B)

    Search CenterWatch for drugs/clinical trials and news about RPRD1B / RPR1B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPRD1B gene: 
    NM_021215.3  

    Unigene Cluster for RPRD1B:

    Regulation of nuclear pre-mRNA domain containing 1B
    Hs.278839  [show with all ESTs]
    Unigene Representative Sequence: NM_021215
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373433(uc002xho.4 uc002xhp.4) ENST00000462548 ENST00000495457
    ENST00000449186 ENST00000471511 ENST00000484683
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidRPRD1B 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK092567.1 AK312468.1 AL080224.1 AL117521.1 BC001696.2 BC020939.1 BC033629.1 DQ372938.1 

    12 DOTS entries:

    DT.100747183  DT.120818839  DT.97773885  DT.446745  DT.95122094  DT.120818916  DT.120818888  DT.40129132 
    DT.91753847  DT.95141814  DT.99985840  DT.75167381 

    24/198 AceView cDNA sequences (see all 198):

    BC020939 AI346125 AI802167 AW450508 AL117521 AW020580 BP359144 BM545387 
    AI280965 AI969554 BX112365 AA364419 BP357464 BU180788 N70934 BP353988 
    H59904 Z41347 AA741155 H88159 BM454427 AI346404 BC001696 AI678621 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for RPRD1B (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c
    SP1:                                -                             -     -           -     -                     
    SP2:                                                              -     -           -     -                     
    SP3:                          -     -                                                                           
    SP4:                    -           -                                                                           
    SP5:                                                                    -                                       


    ECgene alternative splicing isoforms for RPRD1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPRD1B expression in normal human tissues (normalized intensities)      RPRD1B embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTGAGAAC
    RPRD1B Expression
    About this image


    RPRD1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Mandibular Arch Muscles
     
     Lung (Respiratory System)
             trachea   
     
     Eye (Sensory Organs)
             retinal progenitor cell e12.5   

    See RPRD1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPRD1B

    SOURCE GeneReport for Unigene cluster: Hs.278839

    UniProtKB/Swiss-Prot: RPR1B_HUMAN, Q9NQG5
    Tissue specificity: Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast,
    prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent
    non-tumor tissue (at protein level)

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPRD1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPRD1B gene from 10/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rprd1b1 , 5 regulation of nuclear pre-mRNA domain containing 1B1, 5 92.41(n)1
    99.69(a)1
      2 (78.72 cM)5
    704701  NM_027434.21  NP_081710.11 
     1580284975 
    chicken
    (Gallus gallus)
    Aves RPRD1B1 regulation of nuclear pre-mRNA domain containing 1B 83.69(n)
    96.62(a)
      419295  NM_001030862.1  NP_001026033.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPRD1B6
    Uncharacterized protein
    95(a)
    1 ↔ 1
    GL343572.1(122060-192775)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.293082 Xenopus laevis transcribed sequence with weak similarity more 76.48(n)    BU912672.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb23h082 wufb23h08 74.92(n)   321636  BC048885.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90181 CG9018 52.98(n)
    50(a)
      38283  NM_139444.1  NP_647701.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cids-16
    CID domain-containing protein 1
    22(a)
    1 → many
    III(8244443-8245794)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RTT103(YDR289C)4 Protein that interacts with exonuclease Rat1p and Rai1p more   --   4(1039509-1038280) 851884  NP_010575.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G651801 ENTH/VHS family protein 43.35(n)
    31.8(a)
      836642  NM_125916.2  NP_569007.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g06367001 hypothetical protein 42.12(n)
    28.72(a)
      4337145  NM_001060555.1  NP_001054020.1 


    ENSEMBL Gene Tree for RPRD1B (if available)
    TreeFam Gene Tree for RPRD1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPRD1B gene
    RPRD1A2  RPRD22  
    1 SIMAP similar gene for RPRD1B using alignment to 4 protein entries:     RPR1B_HUMAN (see all proteins):
    RPRD1A

    RPRD1B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RPRD1B
    PGOHUM00000258034


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1202 SNPs in RPRD1B are shown (see all 1202)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs741798851,2
    C--36639039(+) GTTCA-/T/TTT 
            
    TTTTT
    2 -- int1 cds11NA 2
    rs1921281371,2
    --36663873(+) CTACAA/GCAGGC 1 -- int10--------
    rs1480307971,2
    C--36663944(+) GGACTC/GCCCCC 1 -- int10--------
    rs1417505051,2
    --36663956(+) AATATC/TGCGTA 1 -- int10--------
    rs1827230831,2
    --36663957(+) ATATCC/GCGTAC 1 -- int10--------
    rs1859079291,2
    --36663981(+) GGATCC/TCCTCA 1 -- int10--------
    rs1899833101,2
    --36663983(+) ATCCCC/GTCAGC 1 -- int10--------
    rs1459600881,2
    --36663999(+) GGGCAG/TTTCCG 1 -- int10--------
    rs1398724611,2
    C--36664003(+) AGTTCC/TGGGAA 1 -- int10--------
    rs761972121,2
    F--36664104(+) CCACTG/CTACAG 1 -- int11Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for RPRD1B (36661948 - 36720768 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RPRD1B:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2670839CNV Deletion23128226
    nsv833972CNV Loss17160897
    nsv833971CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614694    OMIM disorders: --

    6 diseases for RPRD1B:    About MalaCards
    cercarial dermatitis    gnathomiasis    dermatitis    cervical cancer
    cervicitis    prostatitis


    RPRD1B for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPRD1B

    Export disorders for RPRD1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPRD1B gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with RPRD1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Control of the RNA polymerase II phosphorylation stat e in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. (PubMed id 22231121)1, 2, 3 Ni Z....Greenblatt J.F. (2011)
    2. CREPT accelerates tumorigenesis by regulating the transcription of cell-cycle-related genes. (PubMed id 22264791)1, 2 Lu D.... Chang Z. (2012)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 58490 HGNC: 16209 AceView: C20orf77 Ensembl:ENSG00000101413 euGenes: HUgn58490
    ECgene: RPRD1B H-InvDB: RPRD1B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPRD1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPRD1B gene:
    Search GeneIP for patents involving RPRD1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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