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RPRD1A Gene

protein-coding   GIFtS: 52
GCID: GC18M033569

Regulation Of Nuclear Pre-MRNA Domain Containing 1A

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Regulation Of Nuclear Pre-MRNA Domain Containing 1A1 2     HsT31012
P15RS2 3 5     Regulation Of Nuclear Pre-MRNA Domain-Containing Protein 1A2
Cyclin-Dependent Kinase 2B-Inhibitor-Related Protein1 2     Cyclin-Dependent Kinase Inhibitor 2B-Related Protein3
Cyclin-Dependent Kinase Inhibitor 2B-Related Protein (P15INK4B-Related
Protein)1 2
     FLJ106565
P15INK4B-Related Protein2 3     

External Ids:    HGNC: 255601   Entrez Gene: 551972   Ensembl: ENSG000001414257   OMIM: 6103475   UniProtKB: Q96P163   

Export aliases for RPRD1A gene to outside databases

Previous GC identifers: GC18M031824 GC18M030428


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPRD1A Gene:
P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and
may have a role in cell cycle regulation (Liu et al., 2002 (PubMed 12470661)).(supplied by OMIM, Mar 2008)

GeneCards Summary for RPRD1A Gene:
RPRD1A (regulation of nuclear pre-mRNA domain containing 1A) is a protein-coding gene. An important paralog of this gene is RPRD1B.

UniProtKB/Swiss-Prot: RPR1A_HUMAN, Q96P16
Function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase
II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1
(CCND1) and cyclin-E (CCNE1) in the cell cycle




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010966.15  NC_018929.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPRD1A gene promoter:
         AhR   Sp1   HTF   Arnt   Pax-3   POU2F1   POU2F1b   POU2F1a   POU2F1c   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPRD1A promoter sequence
   Search Chromatin IP Primers for RPRD1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPRD1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q12.2   Ensembl cytogenetic band:  18q12.2   HGNC cytogenetic band: 18q12.2

RPRD1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPRD1A gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M033569:  view genomic region     (about GC identifiers)

Start:
33,564,350 bp from pter      End:
33,647,539 bp from pter
Size:
83,190 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RPR1A_HUMAN, Q96P16 (See protein sequence)
Recommended Name: Regulation of nuclear pre-mRNA domain-containing protein 1A  
Size: 312 amino acids; 35720 Da
Subunit: Associates with the RNA polymerase II complex
Sequence caution: Sequence=AAH10136.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
2 PDB 3D structures from and Proteopedia for RPRD1A:
4JXT (3D)        4NAC (3D)    
Secondary accessions: A8KA42 B2RBA3 Q7Z5G8 Q96FY9 Q9NVL4
Alternative splicing: 2 isoforms:  Q96P16-1   Q96P16-3   

Explore the universe of human proteins at neXtProt for RPRD1A: NX_Q96P16

Explore proteomics data for RPRD1A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RPRD1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060640.2  
    ENSEMBL proteins: 
     ENSP00000468108   ENSP00000468173   ENSP00000467991   ENSP00000381984   ENSP00000349955  
     ENSP00000465444   ENSP00000467268   ENSP00000468209   ENSP00000467949   ENSP00000337476  
     ENSP00000314602  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR006903 RNA_pol_II-bd
     IPR006569 CID_dom
     IPR008942 ENTH_VHS

    Graphical View of Domain Structure for InterPro Entry Q96P16

    ProtoNet protein and cluster: Q96P16

    1 Blocks protein domain: IPB006569 Regulation of nuclear pre-mRNA protein

    UniProtKB/Swiss-Prot: RPR1A_HUMAN, Q96P16
    Similarity: Belongs to the UPF0400 (RTT103) family
    Similarity: Contains 1 CID domain


    Find genes that share domains with RPRD1A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPR1A_HUMAN, Q96P16
    Function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase
    II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1
    (CCND1) and cyclin-E (CCNE1) in the cell cycle
    Induction: Up-regulated in cells overexpressing CDKN2B

    Phenotypes:
         3 GenomeRNAi human phenotypes for RPRD1A:

     Decreased focal adhesion (FA)   Decreased telomerase activity  Increased S DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPRD1A

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    miRTarBase miRNAs that target RPRD1A:
    hsa-mir-181b-5p (MIRT047242), hsa-mir-155-5p (MIRT020628), hsa-mir-20a-5p (MIRT050478), hsa-mir-10a-5p (MIRT047673), hsa-mir-30a-5p (MIRT028472)

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    hsa-miR-607 hsa-miR-300 hsa-miR-3653 hsa-miR-30d hsa-miR-759 hsa-miR-342-3p hsa-miR-30a hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidRPRD1A 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016591DNA-directed RNA polymerase II, holoenzyme IDA--

    Find genes that share ontologies with RPRD1A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPRD1A
    Interactions:

        Search GeneGlobe Interaction Network for RPRD1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPRD1A (Q96P163 ENSP000003499554) via UniProtKB, MINT, STRING, and/or I2D (see all 77)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GSTK1Q9Y2Q33I2D: score=1 
    XRN2ENSP000003663964STRING: ENSP00000366396
    CDC73ENSP000003564054STRING: ENSP00000356405
    POLR2BENSP000003127354STRING: ENSP00000312735
    MED31ENSP000002257284STRING: ENSP00000225728
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070940dephosphorylation of RNA polymerase II C-terminal domain IMP--

    Find genes that share ontologies with RPRD1A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RPRD1A (RPR1A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPRD1A gene: 
    NM_018170.3  

    Unigene Cluster for RPRD1A:

    Regulation of nuclear pre-mRNA domain containing 1A
    Hs.464912  [show with all ESTs]
    Unigene Representative Sequence: AF419845
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587563 ENST00000585879 ENST00000590898 ENST00000399022(uc002kze.1 uc002kzg.3 uc010dmw.3)
    ENST00000357384 ENST00000588737 ENST00000585953 ENST00000591994 ENST00000589050
    ENST00000592674 ENST00000588459 ENST00000337059 ENST00000319040(uc010dmx.3)

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    hsa-miR-607 hsa-miR-300 hsa-miR-3653 hsa-miR-30d hsa-miR-759 hsa-miR-342-3p hsa-miR-30a hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidRPRD1A 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat RPRD1A
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    Additional mRNA sequence: 

    AF419845.1 AK001518.1 AK056810.1 AK292907.1 AK314569.1 BC000225.1 BC010136.2 

    18 DOTS entries:

    DT.100798273  DT.95295061  DT.91756332  DT.408566  DT.121085367  DT.100798268  DT.121085379  DT.121085404 
    DT.121085386  DT.100798270  DT.121380832  DT.121085377  DT.92048565  DT.100798274  DT.100831058  DT.121085360 
    DT.91803099  DT.100673604 

    Selected AceView cDNA sequences (see all 335):

    AW510327 BQ921078 BQ019238 AL709369 AI200929 AA453209 N50338 AA678377 
    BQ719877 AW629593 CB306412 BM903860 W94538 AW964471 AA617863 AW614751 
    BQ720597 Z40502 CR590908 BP368009 N72136 N55902 AI186544 AI339968 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RPRD1A (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b · 12c ^ 13
    SP1:                          -     -     -                                   -                       -     -           -     -         
    SP2:                          -     -     -     -                             -                       -     -                           
    SP3:                          -     -     -     -                             -                       -                                 
    SP4:                          -     -     -     -     -     -                 -                                                         
    SP5:                          -           -                                                                                             


    ECgene alternative splicing isoforms for RPRD1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPRD1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAGATGAA
    RPRD1A Expression
    About this image

    RPRD1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPRD1A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.464912
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RPRD1A gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rprd1a1 , 5 regulation of nuclear pre-mRNA domain containing 1A1, 5 91.24(n)1
    98.72(a)1
      18 (13.18 cM)5
    2252831  NM_144861.21  NP_659110.11 
     244849625 
    chicken
    (Gallus gallus)
    Aves RPRD1A1 regulation of nuclear pre-mRNA domain containing 1A 84.86(n)
    90.84(a)
      420953  NM_001031005.2  NP_001026176.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPRD1A6
    regulation of nuclear pre-mRNA domain containing 1...
    86(a)
    1 ↔ 1
    6(57700492-57715006)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia 1376962422   -- 79.95(n)    137696242 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5605651 regulation of nuclear pre-mRNA domain-containing protein more 68.18(n)
    74.68(a)
      560565  XM_683963.6  XP_689055.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90186
    --
    39(a)
    1 → many
    3L(2235284-2237076)
    worm
    (Caenorhabditis elegans)
    Secernentea cids-11 cids-1 41.7(n)
    26.5(a)
      176162  NM_066406.4  NP_498807.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RTT1036
    Protein that interacts with exonuclease Rat1p and ...
    14(a)
    1 → many
    IV(1038280-1039509) YDR289C


    ENSEMBL Gene Tree for RPRD1A (if available)
    TreeFam Gene Tree for RPRD1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPRD1A gene
    RPRD1B2  RPRD22  
    1 SIMAP similar gene for RPRD1A using alignment to 4 protein entries:     RPR1A_HUMAN (see all proteins):
    RPRD1B

    Find genes that share paralogs with RPRD1A           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for RPRD1A
    PGOHUM00000249129


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPRD1A (see all 1537)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0372294
    A breast cancer sample4--see VAR_0372292 Q H mis40--------
    rs1427653801,2
    --30428237(+) CAGTGA/GCATCA 1 -- int10--------
    rs777691401,2
    F--30428502(+) AAGCCG/ATCCTG 1 -- int11Minor allele frequency- A:0.04WA 118
    rs739467541,2
    C,F--30428514(+) GTCACG/ATGCAG 1 -- int13Minor allele frequency- A:0.18WA CSA 122
    rs1502924211,2
    C--30428842(+) CCTCAA/GAACAG 1 -- ut310--------
    rs1924533821,2
    --30428988(+) TATGAA/GACAAG 1 -- ut310--------
    rs1125693231,2
    C,F--30429141(+) TTTTTC/TTCTCT 1 -- ut311Minor allele frequency- T:0.50WA 2
    rs1896382331,2
    --30429205(+) ATCTAC/TAGTGA 1 -- ut310--------
    rs1379489731,2
    C--30429283(+) CTGAAA/GGATTT 1 -- ut310--------
    rs1817724141,2
    --30429301(+) AAAAAC/TCCTGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RPRD1A (33564350 - 33647539 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RPRD1A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1506593CNV Insertion17803354
    esv275291CNV Loss21479260
    nsv522157CNV Loss19592680
    esv25678CNV Loss19812545
    nsv7303OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610347    OMIM disorders: --


    Find genes that share disorders with RPRD1A           About GenesLikeMe

    1 Novoseek inferred disease relationship for RPRD1A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 5.79 2 9892092 (1)


    Export disorders for RPRD1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPRD1A gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with RPRD1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of P15RS, a novel P15(INK4b) related gene on G1/S progression. (PubMed id 12470661)1, 2, 3, 9 Liu J.... Hu Z. (Biochem. Biophys. Res. Commun. 2002)
    2. Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. (PubMed id 22231121)1, 2, 3 Ni Z.... Greenblatt J.F. (Transcription 2011)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    5. Cellular and molecular evidence for malignancy-inhibitory functions of p15RS. (PubMed id 22580456)1 Zhang X....Zhang W. (Cell Cycle 2012)
    6. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55197 HGNC: 25560 AceView: P15RS Ensembl:ENSG00000141425 euGenes: HUgn55197
    ECgene: RPRD1A H-InvDB: RPRD1A

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPRD1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RPRD1A gene:
    Search GeneIP for patents involving RPRD1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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