Subcategory (RNA class) for RPPH1-3P Gene
Previous GeneCards Identifiers for RPPH1-3P Gene
GeneCards Summary for RPPH1-3P Gene
RPPH1-3P (Ribonuclease P RNA Component H1, 3 Pseudogene) is a Pseudogene, and is affiliated with the lncRNA class.
fRNAdb sequence ontologies for RPPH1-3P Gene
RNase_P_RNA: The RNA component of Ribonuclease P (RNase P), a ubiquitous endoribonuclease, found in archaea, bacteria and eukarya as well as chloroplasts and mitochondria. Its best characterised activity is the generation of mature 5 prime ends of tRNAs by cleaving the 5 prime leader elements of precursor-tRNAs. Cellular RNase Ps are ribonucleoproteins. RNA from bacterial RNase Ps retains its catalytic activity in the absence of the protein subunit, i.e. it is a ribozyme. Isolated eukaryotic and archaeal RNase P RNA has not been shown to retain its catalytic function, but is still essential for the catalytic activity of the holoenzyme. Although the archaeal and eukaryotic holoenzymes have a much greater protein content than the bacterial ones, the RNA cores from all the three lineages are homologous. Helices corresponding to P1, P2, P3, P4, and P10/11 are common to all cellular RNase P RNAs. Yet, there is considerable sequence variation, particularly among the eukaryotic RNAs.