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Aliases for RPPH1 Gene

Subcategory (RNA class) for RPPH1 Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for RPPH1 Gene

  • Ribonuclease P RNA Component H1 2 3 5
  • RPPH1-1 3
  • H1 RNA 3
  • H1RNA 3

External Ids for RPPH1 Gene

ORGUL Members for RPPH1 Gene

Previous GeneCards Identifiers for RPPH1 Gene

  • GC14U900464
  • GC14M019884
  • GC14M020811
  • GC14M000933

Summaries for RPPH1 Gene

Entrez Gene Summary for RPPH1 Gene

  • H1RNA is the RNA component of the RNase P ribonucleoprotein, an endoribonuclease that cleaves tRNA precursor molecules to form the mature 5-prime termini of their tRNA sequences (Baer et al., 1989 [PubMed 2308839]).[supplied by OMIM, Mar 2008]

GeneCards Summary for RPPH1 Gene

RPPH1 (Ribonuclease P RNA Component H1) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for RPPH1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPPH1 Gene

Genomics for RPPH1 Gene

GeneHancer (GH) Regulatory Elements for RPPH1 Gene

Promoters and enhancers for RPPH1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I020341 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 +0.2 207 3 HDGF PKNOX1 FOXA2 SMAD1 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 PARP2 ENSG00000259001 RPPH1 METTL17 ENSG00000258768 TEP1 ENSG00000258515 PIP4P1 APEX1 HNRNPC
GH14I020334 Enhancer 0.4 FANTOM5 0.4 +8.5 8493 0.1 ZBTB17 CCNB1IP1 RPPH1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RPPH1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RPPH1 gene promoter:

Genomic Locations for RPPH1 Gene

Genomic Locations for RPPH1 Gene
chr14:20,343,071-20,343,411
(GRCh38/hg38)
Size:
341 bases
Orientation:
Minus strand
chr14:20,811,207-20,811,844
(GRCh37/hg19)

Genomic View for RPPH1 Gene

Genes around RPPH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPPH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPPH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPPH1 Gene

Proteins for RPPH1 Gene

Post-translational modifications for RPPH1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RPPH1 Gene

Domains & Families for RPPH1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RPPH1 Gene

Function for RPPH1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RPPH1 Gene

Localization for RPPH1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RPPH1 Gene

Pathways & Interactions for RPPH1 Gene

SuperPathways for RPPH1 Gene

No Data Available

Interacting Proteins for RPPH1 Gene

Gene Ontology (GO) - Biological Process for RPPH1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RPPH1 Gene

Drugs & Compounds for RPPH1 Gene

No Compound Related Data Available

Transcripts for RPPH1 Gene

mRNA/cDNA for RPPH1 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RPPH1 Gene

Ribonuclease P RNA component H1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RPPH1 Gene

No ASD Table

Relevant External Links for RPPH1 Gene

GeneLoc Exon Structure for
RPPH1
ECgene alternative splicing isoforms for
RPPH1

Expression for RPPH1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RPPH1 Gene

mRNA differential expression in normal tissues according to GTEx for RPPH1 Gene

This gene is overexpressed in Whole Blood (x5.1).

NURSA nuclear receptor signaling pathways regulating expression of RPPH1 Gene:

RPPH1

SOURCE GeneReport for Unigene cluster for RPPH1 Gene:

Hs.613102
genes like me logo Genes that share expression patterns with RPPH1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPPH1 Gene

Orthologs for RPPH1 Gene

Evolution for RPPH1 Gene

ENSEMBL:
Gene Tree for RPPH1 (if available)
TreeFam:
Gene Tree for RPPH1 (if available)

No data available for Orthologs for RPPH1 Gene

Paralogs for RPPH1 Gene

No data available for Paralogs for RPPH1 Gene

Variants for RPPH1 Gene

Sequence variations from dbSNP and Humsavar for RPPH1 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1001497765 -- 20,343,190(-) T/C non_coding_transcript_variant
rs1001551705 -- 20,342,703(-) C/G downstream_transcript_variant
rs1002100857 -- 20,343,392(-) T/C non_coding_transcript_variant
rs1002504072 -- 20,343,447(-) C/G upstream_transcript_variant
rs1002556420 -- 20,343,414(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RPPH1 Gene

Variant ID Type Subtype PubMed ID
esv23438 CNV gain+loss 19812545
nsv1042025 CNV loss 25217958

Additional Variant Information for RPPH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RPPH1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RPPH1 Gene

Disorders for RPPH1 Gene

Additional Disease Information for RPPH1

No disorders were found for RPPH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPPH1 Gene

Publications for RPPH1 Gene

  1. Recent studies of ribonuclease P. (PMID: 7916700) Altman S … Talbot S (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993) 2 3 58
  2. Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells. (PMID: 2470644) Bartkiewicz M … Altman S (Genes & development 1989) 2 3 58
  3. Developmental validation of the Quantifiler Duo DNA Quantification kit for simultaneous quantification of total human and human male DNA and detection of PCR inhibitors in biological samples. (PMID: 19175708) Barbisin M … Shewale JG (Journal of forensic sciences 2009) 22 58
  4. RNA polymerase II mediated transcription from the polymerase III promoters in short hairpin RNA expression vector. (PMID: 16300730) Rumi M … Kinoshita Y (Biochemical and biophysical research communications 2006) 22 58
  5. Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. (PMID: 15096576) Welting TJ … Pruijn GJ (Nucleic acids research 2004) 3 58

Products for RPPH1 Gene

Sources for RPPH1 Gene

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