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RPP25 Gene

protein-coding   GIFtS: 50
GCID: GC15M075247

Ribonuclease P/MRP 25kDa Subunit

(Previous name: ribonuclease P 25kDa subunit)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribonuclease P/MRP 25kDa Subunit1 2
RNase P Protein Subunit P251 2 3
Ribonuclease P 25kDa Subunit1 2
Ribonuclease P Protein Subunit P252
EC 3.1.26.53

External Ids:    HGNC: 303611   Entrez Gene: 549132   Ensembl: ENSG000001787187   UniProtKB: Q9BUL93   

Export aliases for RPP25 gene to outside databases

Previous GC identifers: GC15M072964 GC15M073034 GC15M052044


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RPP25 Gene:
RPP25 (ribonuclease P/MRP 25kDa subunit) is a protein-coding gene. Diseases associated with RPP25 include cartilage-hair hypoplasia, and autism spectrum disorder. GO annotations related to this gene include ribonuclease P activity and RNA binding. An important paralog of this gene is RPP25L.

UniProtKB/Swiss-Prot: RPP25_HUMAN, Q9BUL9
Function: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their
5'-ends. Also a component of RNase MRP. This subunit binds to RNA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPP25 gene promoter:
         Max1   Spz1   p53   AP-1   ATF-2   Nkx5-1   NF-kappaB   c-Jun   Pax-4a   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPP25 promoter sequence
   Search Chromatin IP Primers for RPP25

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPP25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24.2   Ensembl cytogenetic band:  15q24.2   HGNC cytogenetic band: 15q24.2

RPP25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPP25 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M075247:  view genomic region     (about GC identifiers)

Start:
75,246,757 bp from pter      End:
75,249,805 bp from pter
Size:
3,049 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RPP25_HUMAN, Q9BUL9 (See protein sequence)
Recommended Name: Ribonuclease P protein subunit p25  
Size: 199 amino acids; 20632 Da
Subunit: Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at
least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. Interacts with the
P3 domain of RNase MRP complex. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14,
RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21
Secondary accessions: D3DW70 Q9NX88

Explore the universe of human proteins at neXtProt for RPP25: NX_Q9BUL9

Explore proteomics data for RPP25 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RPP25 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060263.2  
    ENSEMBL proteins: 
     ENSP00000317691   ENSP00000446246  

    RPP25 Human Recombinant Protein Products:

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    RPP25 Assay Products:

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    Cloud-Clone Corp. CLIAs for RPP25


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR002775 DNA/RNA-bd_Alba-like

    Graphical View of Domain Structure for InterPro Entry Q9BUL9

    ProtoNet protein and cluster: Q9BUL9

    1 Blocks protein domain: IPB002775 Alba

    UniProtKB/Swiss-Prot: RPP25_HUMAN, Q9BUL9
    Similarity: Belongs to the histone-like Alba family


    RPP25 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPP25_HUMAN, Q9BUL9
    Function: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their
    5'-ends. Also a component of RNase MRP. This subunit binds to RNA
    Catalytic activity: Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor

         Enzyme Number (IUBMB): EC 3.1.26.51

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0004526ribonuclease P activity IEA--
    GO:0005515protein binding IPI15096576
    GO:0044822poly(A) RNA binding IDA--
         
    RPP25 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RPP25:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPP25
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPP25
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    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate RPP25:
    hsa-miR-550a hsa-miR-1266 hsa-miR-24 hsa-miR-488 hsa-miR-766
    SwitchGear 3'UTR luciferase reporter plasmidRPP25 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RPP25

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPP25


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RPP25_HUMAN, Q9BUL9: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton4
    mitochondrion4
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005739mitochondrion ----
    GO:0005813centrosome ----

    RPP25 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPP25 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA transport
    RNA transport
    2Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for RPP25):
        Ribosome biogenesis in eukaryotes
    RNA transport


    RPP25 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPP25
    Interactions:

        GeneGlobe Interaction Network for RPP25

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for RPP25 (Q9BUL91, 3 ENSP000003176914) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POP7O758171, 3, ENSP000003043534EBI-366570,EBI-366574 I2D: score=4 STRING: ENSP00000304353
    POP4O957071, 3, ENSP000002217704EBI-366570,EBI-366477 I2D: score=4 STRING: ENSP00000221770
    POP1Q995753, ENSP000003395294I2D: score=4 STRING: ENSP00000339529
    POP5Q969H63, ENSP000003500984I2D: score=3 STRING: ENSP00000350098
    RPP14O950593, ENSP000002959594I2D: score=2 STRING: ENSP00000295959
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008033tRNA processing IEA--

    RPP25 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPP25



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPP25 gene: 
    NM_017793.2  

    Unigene Cluster for RPP25:

    Ribonuclease P/MRP 25kDa subunit
    Hs.8562  [show with all ESTs]
    Unigene Representative Sequence: NM_017793
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322177(uc002azj.1) ENST00000499788
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate RPP25:
    hsa-miR-550a hsa-miR-1266 hsa-miR-24 hsa-miR-488 hsa-miR-766
    SwitchGear 3'UTR luciferase reporter plasmidRPP25 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RPP25
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    GenScript: all cDNA clones in your preferred vector: RPP25 (NM_017793)
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    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RPP25
    OriGene qSTAR qPCR primer pairs in human, mouse for RPP25
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat RPP25
      QuantiTect SYBR Green Assays in human, mouse, rat RPP25
      QuantiFast Probe-based Assays in human, mouse, rat RPP25

    Additional mRNA sequence: 

    BC002497.2 BC007270.1 

    6 DOTS entries:

    DT.100784701  DT.415545  DT.92444066  DT.121055790  DT.100765341  DT.95315606 

    Selected AceView cDNA sequences (see all 232):

    CR595106 BE255945 BF445261 CR608482 AA557262 AA480595 BM764819 BM550308 
    BF726302 AI093902 BE206992 CR594166 BM757201 BM842493 AA411651 CR619276 
    BQ064707 BQ221947 BI257840 BM980849 BM843568 BF726303 BC007270 BP340210 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPP25 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACCTTAAGG
    RPP25 Expression
    About this image


    RPP25 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
    RPP25 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPP25 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.8562
        Custom PCR Arrays for RPP25
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPP25

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RPP25 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpp251 , 5 ribonuclease P 25 subunit (human)5
    ribonuclease P/MRP 25 subunit1
    86.26(n)1
    87.94(a)1
      9 (31.05 cM)5
    1026141  NM_133982.11  NP_598743.11 
     575041025 
    chicken
    (Gallus gallus)
    Aves RPP251 ribonuclease P/MRP 25kDa subunit 65.95(n)
    62.14(a)
      430848  XM_004943679.1  XP_004943736.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPP256
    ribonuclease P/MRP 25kDa subunit
    49(a)
    1 ↔ 1
    GL343492.1(536077-536616)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rpp251 ribonuclease P/MRP 25kDa subunit 55.71(n)
    52.14(a)
      100496900  XM_004915991.1  XP_004916048.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018851681 uncharacterized LOC101885168 63.1(n)
    57.86(a)
      101885168  XM_005173600.1  XP_005173657.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG94226
    --
    31(a)
    1 → many
    2R(2563333-2580376)


    ENSEMBL Gene Tree for RPP25 (if available)
    TreeFam Gene Tree for RPP25 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPP25 gene
    RPP25L2  
    1 SIMAP similar gene for RPP25 using alignment to 1 protein entry:     RPP25_HUMAN:
    RPP25L

    RPP25 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPP25 (see all 71)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs124407071,2
    C,H--75246945(+) CCCCAC/ACCCCC 1 -- ds50015Minor allele frequency- A:0.00NS EA NA 420
    rs1493390401,2
    C--75247037(+) TATCAA/GGAGGC 1 -- ds50010--------
    rs1446921811,2
    --75247128(+) CTCCCA/CCTTTC 1 -- ds50010--------
    rs1889021391,2
    --75247129(+) TCCCCC/TTTTCC 1 -- ds50010--------
    rs340636701,2
    C,F--75247156(+) TTTCTC/GAGAGA 1 -- ds500111Minor allele frequency- G:0.26NA EA CSA WA 728
    rs1485160211,2
    --75247183(+) AGATCC/TTACCC 1 -- ds50010--------
    rs1811847921,2
    C--75247592(+) CAGGCA/GAGAGC 1 -- ut310--------
    rs1428640441,2
    C--75247706(+) AGGAGA/GCCTGG 1 -- ut310--------
    rs115402661,2
    C--75247755(-) CACCCC/ATTTTC 1 -- ut311Minor allele frequency- A:0.00NA 2
    rs1401288981,2
    C--75247857(+) GGCCCC/GCACAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RPP25 (75246757 - 75249805 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RPP25:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1612CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPP25
    DNA2.0 Custom Variant and Variant Library Synthesis for RPP25

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for RPP25:    
    About MalaCards
    cartilage-hair hypoplasia    autism spectrum disorder    cerebritis

    1 disease from the University of Copenhagen DISEASES database for RPP25:
    cartilage-hair hypoplasia

    RPP25 for disorders           About GeneDecksing


    Export disorders for RPP25 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPP25 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with RPP25)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Purification and characterization of Rpp25, an RNA-binding protein subunit of human ribonuclease P. (PubMed id 12003489)1, 2, 3, 9 Guerrier-Takada C.... Altman S. (RNA 2002)
    2. Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. (PubMed id 15096576)1, 2 Welting T.J.... Pruijn G.J. (Nucleic Acids Res. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (amp 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. (PubMed id 20632321)1 Huang H.S....Akbarian S. (Autism Res 2010)
    10. Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA. (PubMed id 20215441)1 Hands-Taylor K.L....Conte M.R. (Nucleic Acids Res. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54913 HGNC: 30361 AceView: RPP25 Ensembl:ENSG00000178718 euGenes: HUgn54913
    ECgene: RPP25 Kegg: 54913 H-InvDB: RPP25

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPP25 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPP25 gene:
    Search GeneIP for patents involving RPP25

    GeneCards and IP:
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