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RPP14 Gene

protein-coding   GIFtS: 52
GCID: GC03P058295

Ribonuclease P/MRP 14kDa Subunit

(Previous name: ribonuclease P 14kDa subunit)
  Search for RPP14
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ribonuclease P/MRP 14kDa Subunit1 2     3-Hydroxyacyl-[Acyl-Carrier-Protein] Dehydratase3
Ribonuclease P 14kDa Subunit1     EC 3.1.26.53
P142     EC 4.2.1.-3
Ribonuclease P Protein Subunit P142     HsHTD23

External Ids:    HGNC: 303271   Entrez Gene: 111022   Ensembl: ENSG000001636847   OMIM: 6061125   UniProtKB: P863973   
UniProtKB: O950593   
ORGUL members:         

Export aliases for RPP14 gene to outside databases

Previous GC identifers: GC03M057092 GC03P057660 GC03P058146 GC03P058249 GC03P058224 GC03P058267


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RPP14 Gene:
RPP14 (ribonuclease P/MRP 14kDa subunit) is a protein-coding gene. GO annotations related to this gene include ribonuclease P activity and RNA binding.

UniProtKB/Swiss-Prot: RPP14_HUMAN, O95059
Function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends

Gene Wiki entry for RPP14 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_022517.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPP14 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-1   E2F   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPP14 promoter sequence
   Search Chromatin IP Primers for RPP14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPP14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14.3   Ensembl cytogenetic band:  3p14.3   HGNC cytogenetic band: 3p21.2

RPP14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPP14 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P058295:  view genomic region     (about GC identifiers)

Start:
58,291,972 bp from pter      End:
58,310,422 bp from pter
Size:
18,451 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HTD2_HUMAN, P86397 (See protein sequence)
Recommended Name: Hydroxyacyl-thioester dehydratase type 2, mitochondrial precursor  
Size: 168 amino acids; 18559 Da
Miscellaneous: This protein is produced by a bicistronic gene which also produces the RPP14 protein from an
overlapping reading frame
1 PDB 3D structure from and Proteopedia for RPP14:
3IR3 (3D)    

UniProtKB/Swiss-Prot: RPP14_HUMAN, O95059 (See protein sequence)

Recommended Name: Ribonuclease P protein subunit p14  
Size: 124 amino acids; 13693 Da
Subunit: RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25,
RPP29/POP4, RPP30, RPP38 and RPP40
Miscellaneous: This protein is produced by a bicistronic gene which also produces the HTD2 protein from an
overlapping reading frame
Secondary accessions: Q53X97

Explore the universe of human proteins at neXtProt for RPP14: NX_O95059

Explore proteomics data for RPP14 at MOPED


See RPP14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001092253.1  NP_008973.1  

ENSEMBL proteins: 
 ENSP00000412894   ENSP00000295959   ENSP00000419909  

RPP14 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR002539 MaoC_dom
 IPR002759 RNase_P/MRP_subunit

Graphical View of Domain Structure for InterPro Entry P86397
Graphical View of Domain Structure for InterPro Entry O95059

ProtoNet protein and cluster: P86397

UniProtKB/Swiss-Prot: HTD2_HUMAN, P86397
Similarity: Belongs to the HTD2 family
Similarity: Contains 1 MaoC-like domain

UniProtKB/Swiss-Prot: RPP14_HUMAN, O95059
Similarity: Belongs to the eukaryotic/archaeal RNase P protein component 2 family


Find genes that share domains with RPP14           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: HTD2_HUMAN, P86397
Function: Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis
Catalytic activity: (3R)-hydroxyacyl-CoA = trans-2-enoyl-CoA + H(2)O
Catalytic activity: (3R)-hydroxyacyl-[acyl-carrier-protein] = trans-2-enoyl-[acyl-carrier-protein] + H(2)O

     UniProtKB/Swiss-Prot: RPP14_HUMAN, O95059
Function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends
Catalytic activity: Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor

     Enzyme Numbers (IUBMB): EC 3.1.26.51 EC 4.2.1.-1

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003723RNA binding TAS10024167
GO:0004526ribonuclease P activity IEA--
GO:0004540ribonuclease activity ----
     
Find genes that share ontologies with RPP14           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPP14
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPP14

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPP14
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPP14

miRNA
Products:
    
miRTarBase miRNAs that target RPP14:
hsa-mir-326 (MIRT043625), hsa-mir-30a-5p (MIRT028571)

Block miRNA regulation of human, mouse, rat RPP14 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate RPP14 (see all 53):
hsa-miR-142-5p hsa-miR-2052 hsa-miR-4291 hsa-miR-596 hsa-miR-328 hsa-miR-19b-2* hsa-miR-3653 hsa-miR-507
SwitchGear 3'UTR luciferase reporter plasmidRPP14 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat RPP14

Gene Editing
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GenScript: all cDNA clones in your preferred vector (see all 2): RPP14 (NM_007042)
Sino Biological Human cDNA Clone for RPP14
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPP14
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPP14

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPP14


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
HTD2_HUMAN, P86397: Mitochondrion
RPP14_HUMAN, O95059: Nucleus (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus4
cytosol1
extracellular1
mitochondrion1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

Find genes that share ontologies with RPP14           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for RPP14 About    
See pathways by source

SuperPathContained pathways About
1RNA transport
RNA transport


Find genes that share SuperPaths with RPP14           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways




1 Kegg Pathway  (Kegg details for RPP14):
    RNA transport

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPP14
Interactions:

    Search GeneGlobe Interaction Network for RPP14

STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

Selected Interacting proteins for RPP14 (O950592, 3 ENSP000002959594) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
InteractantInteraction Details
GeneCardExternal ID(s)
IGSF21Q96ID52, 3, ENSP000002512964MINT-63243 I2D: score=4 STRING: ENSP00000251296
ENSG00000272333Q9UMN62, 3MINT-8269153 I2D: score=2 
KMT2BQ9UMN62, 3MINT-8269153 I2D: score=2 
NOVA1P515132, 3, ENSP000002674224MINT-8269175 I2D: score=2 STRING: ENSP00000267422
A2MP010232, 3MINT-8269109 I2D: score=2 
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008033tRNA processing IEA--

Find genes that share ontologies with RPP14           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for RPP14



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for RPP14 gene (2 alternative transcripts): 
NM_001098783.2  NM_007042.4  

Unigene Cluster for RPP14:

Ribonuclease P/MRP 14kDa subunit
Hs.446320  [show with all ESTs]
Unigene Representative Sequence: NM_001098783
13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000461797 ENST00000475412 ENST00000445193(uc010hnh.3 uc010hni.3)
ENST00000474660 ENST00000477305 ENST00000295959 ENST00000466547 ENST00000481972
ENST00000498618 ENST00000461393 ENST00000476007 ENST00000463550 ENST00000462046

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat RPP14 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate RPP14 (see all 53):
hsa-miR-142-5p hsa-miR-2052 hsa-miR-4291 hsa-miR-596 hsa-miR-328 hsa-miR-19b-2* hsa-miR-3653 hsa-miR-507
SwitchGear 3'UTR luciferase reporter plasmidRPP14 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for RPP14
Predesigned siRNA for gene silencing in human, mouse, rat RPP14
Clone
Products:
     
OriGene clones in human, mouse for RPP14 (see all 12)
OriGene ORF clones in mouse, rat for RPP14
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): RPP14 (NM_007042)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPP14
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPP14
Primer
Products:
    
OriGene qPCR primer pairs and template standards for RPP14
OriGene qSTAR qPCR primer pairs in human, mouse for RPP14
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPP14
  QuantiTect SYBR Green Assays in human, mouse, rat RPP14
  QuantiFast Probe-based Assays in human, mouse, rat RPP14

Additional mRNA sequence: 

AF001175.1 AK056070.1 AK311396.1 AK311969.1 BC002441.1 BC007342.1 BC012017.1 CR407611.1 
NR_049755.1 NR_049756.1 NR_049757.1 NR_049758.1 

12 DOTS entries:

DT.115264  DT.444287  DT.95270042  DT.95185112  DT.120918636  DT.120918643  DT.120918618  DT.95337769 
DT.65287248  DT.95196227  DT.120918624  DT.95358966 

Selected AceView cDNA sequences (see all 264):

AA724224 BE502834 BQ228154 AI224522 BF439230 CR607469 AA580130 CR593615 
AI268541 AA769552 BC012017 BE671384 BF108748 AA835816 CF272450 CA308551 
AI200075 BM680817 AA478947 AI249128 AA987334 BU159844 AL561376 AA476338 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for RPP14 (see all 10)    About this scheme

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g
SP1:                          -     -     -     -     -                 -     -                                                               
SP2:                          -     -     -     -     -     -           -                                                                     
SP3:                                      -     -     -                 -     -                                                               
SP4:                          -     -     -     -     -                                                                                       
SP5:                          -     -     -     -     -     -           -     -                                                               


ECgene alternative splicing isoforms for RPP14

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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RPP14 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TATCAGTACA
RPP14 Expression
About this image


RPP14 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Brain (Nervous System)    fully expand to see all 2 entries
         Cerebral Cortex
 
 Thymus (Hematopoietic System)
         Thymus
 
 Gut Tube (Gastrointestinal Tract)
         Foregut
 
 Kidney (Urinary System)
         Metanephros
 
 Neural Tube (Nervous System)
         Telencephalon
RPP14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

RPP14 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.446320

UniProtKB/Swiss-Prot: HTD2_HUMAN, P86397
Tissue specificity: Highly expressed in heart and liver. Expressed at lower levels in skeletal muscle, spleen,
kidney and placenta


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Primer
Products:
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OriGene qSTAR qPCR primer pairs in human, mouse for RPP14
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPP14
QuantiTect SYBR Green Assays in human, mouse, rat RPP14
QuantiFast Probe-based Assays in human, mouse, rat RPP14
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPP14

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for RPP14 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Rpp141 , 5 ribonuclease P 14 subunit (human)5
ribonuclease P 14 subunit1
82.92(n)1
85.95(a)1
  14 (4.70 cM)5
670531  NM_025938.41  NP_080214.11 
 80803135 
chicken
(Gallus gallus)
Aves RPP146
ribonuclease P/MRP 14kDa subunit
53(a)
1 ↔ 1
12(11772250-11773722)
lizard
(Anolis carolinensis)
Reptilia RPP146
ribonuclease P/MRP 14kDa subunit
67(a)
1 ↔ 1
2(187318639-187323381)
African clawed frog
(Xenopus laevis)
Amphibia Xl.82042 Xenopus laevis transcribed sequence with weak similarity more 73.61(n)    BJ047180.1 
zebrafish
(Danio rerio)
Actinopterygii BM186106.12   -- 72.34(n)    BM186106.1 


ENSEMBL Gene Tree for RPP14 (if available)
TreeFam Gene Tree for RPP14 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for RPP14 (see all 440)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs600957721,2
C,F--58289973(+) GGTCTG/ATGGGG 6 -- us2k17Minor allele frequency- A:0.46WA NA CSA EA 365
rs677931961,2
C,F--58290129(+) GAAAAT/GAATTG 6 -- us2k16Minor allele frequency- G:0.47WA NA CSA EA 363
rs130948981,2
C,F,H--58290143(+) AAGGAG/AATCCC 6 -- us2k1 trp317Minor allele frequency- A:0.06NS EA NA CSA WA 2134
rs1870116691,2
--58290150(+) TCCCCA/GCTGAC 6 -- us2k10--------
rs622593191,2
C,F--58290358(+) CTCAAT/CTGGTG 6 -- us2k16Minor allele frequency- C:0.47WA NA CSA EA 363
rs1910485991,2
--58290430(+) ACTGTA/GATCTT 6 -- us2k10--------
rs1833639171,2
--58290442(+) AGCAAA/GTAACT 6 -- us2k10--------
rs1872856921,2
--58290509(+) GATCTC/TGGCTT 6 -- us2k10--------
rs622593201,2
C,F--58290629(+) AGAGAC/TGGGGG 6 -- us2k13Minor allele frequency- T:0.40NA CSA 5
rs1913752401,2
--58290645(+) CCATGC/TTGGCC 6 -- us2k10--------

HapMap Linkage Disequilibrium report for RPP14 (58291972 - 58310422 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for RPP14:    About this table    
Variant IDTypeSubtypePubMed ID
nsv528147CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing RPP14
DNA2.0 Custom Variant and Variant Library Synthesis for RPP14

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 606112    OMIM disorders: --


Find genes that share disorders with RPP14           About GenesLikeMe


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(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for RPP14 gene, integrated from 10 sources (see all 22):
(articles sorted by number of sources associating them with RPP14)
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  1. Rpp14 and Rpp29, two protein subunits of human ribonuclease P. (PubMed id 10024167)1, 2, 3, 9 Jarrous N.... Altman S. (RNA 1999)
  2. A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'--&gt;5' exoribonuclease activity. (PubMed id 11929972)1, 3, 9 Jiang T. and Altman S. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
  8. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
  9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
  10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11102 HGNC: 30327 AceView: RPP14 Ensembl:ENSG00000163684 euGenes: HUgn11102
ECgene: RPP14 Kegg: 11102 H-InvDB: RPP14

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for RPP14 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for RPP14 gene:
Search GeneIP for patents involving RPP14

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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