RPN2 Gene
protein-coding GIFtS: 61
GCID: GC20P035806
|
|
ribophorin II
| |
Aliases
for RPN2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ribophorin II1 2 3 | | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 22 | | RIBIIR1 2 3 | | Ribophorin-23 | | RPN-II1 2 3 | | EC 2.4.99.183 | | RPNII1 2 | | Ribophorin-23 | | SWP11 2 | | EC 2.4.1.1198 | | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 KDa Subunit2 3 | | |
Export aliases for RPN2 gene to outside databasesPrevious GC identifers: GC20P035535 GC20P036445 GC20P036492 GC20P035240 GC20P032542 |
Summaries
for RPN2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RPN2:
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded proteinis part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residuesfound in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to theyeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoformshave been found for this gene. (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: RPN2_HUMAN, P04844Function: Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a highmannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thrconsensus motif in nascent polypeptide chains
Gene Wiki entry for RPN2
|
Genomic Views
for RPN2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RPN2 gene promoter:
c-Fos AP-1 AP-2gamma E47 CREB Hand1 AP-2beta c-Jun AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for RPN2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPN2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q12-q13.1 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q12-q13.1RPN2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P035806: view genomic region
(about GC identifiers)
Start:
|
35,806,813 bp from pter |
End:
|
35,870,026 bp from pter |
Size:
|
63,214 bases |
Orientation:
|
plus strand |
|
Proteins
for RPN2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RPN2_HUMAN, P04844 (See
protein sequence)Recommended Name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor Size: 631 amino acids; 69284 Da
Subunit: Component of the oligosaccharyltransferase (OST) complex. OST seems to exist in different forms which containat least RPN1, RPN2, OST48, DAD1, OSTC, KRTCAP2 and either STT3A or STT3B. OST can form stable complexes with theSec61 complex or with both the Sec61 and TRAP complexes (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: Q5JYR6 Q6IBA5 Q96E21 Q9BUQ3 Q9UBE1Alternative splicing: 2 isoforms: P04844-1 P04844-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for RPN2: NX_P04844
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P04844
4/12 DME Specific Peptides for RPN2 (P04844) (see all 12)
RPN2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001129243.1 NP_002942.2
ENSEMBL proteins: ENSP00000399137 ENSP00000237530 ENSP00000362724 ENSP00000362735 ENSP00000435563 ENSP00000409580 ENSP00000399404 Reactome Protein details: P04844
Human Recombinant Protein Products for RPN2:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
RPN2 for ontologies About GeneDecksing
RPN2 Antibody Products:
Assay Products for RPN2: |
Protein
Domains /
Families
for RPN2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPN2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P04844ProtoNet protein and cluster: P04844 UniProtKB/Swiss-Prot: RPN2_HUMAN, P04844Similarity: Belongs to the SWP1 family |
Function
for RPN2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RPN2_HUMAN, P04844Function: Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a highmannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thrconsensus motif in nascent polypeptide chainsCatalytic activity: Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoproteinwith the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine Genatlas biochemistry entry for RPN2:ribophorin II,69.5kDa,component with RPN1 and DDOST of N-oligosacccharyl transferase
Enzyme Numbers (IUBMB): EC 2.4.1.1192 EC 2.4.99.181
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004579 | contributes to dolichyl-diphosphooligosaccharide-protein glycotransferase activity |
NAS | 15835887 | | GO:0043022 | ribosome binding |
IEA | -- |
RPN2 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for RPN2:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Rpn2):
RPN2 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPN2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPN2 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RPN2 (NM_002951) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPN2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPN2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPN2 |
|
Pathways & Interactions
for RPN2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Asparagine N-linked glycosylation | | | 2 | Synthesis of PB1-F2 | | | 3 | Protein processing in endoplasmic reticulum | | | 4 | Ubiquitinated Orc1 is degraded by the proteasome | | | 5 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  GeneGo (Thomson Reuters) Pathway for RPN2
1  BioSystems Pathway for RPN2
5/6 
Reactome Pathways for RPN2 (see all 6)
3 
Kegg Pathways (Kegg details for RPN2):
UniProtKB/Swiss-Prot: RPN2_HUMAN, P04844Pathway: Protein modification; protein glycosylation
RPN2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPN2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/148 Interacting proteins for RPN2 (P048442, 3 ENSP000002375304) via UniProtKB, MINT, STRING, and/or I2D (see all 148)
About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
RPN2 for ontologies About GeneDecksing
|
Drugs & Compounds
for RPN2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RPN2
2 HMDB Compounds for RPN2 About this table
Search CenterWatch for drugs/clinical trials and news about RPN2
|
Transcripts
for RPN2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RPN2 gene (2 alternative transcripts): NM_001135771.1 NM_002951.3 Unigene Cluster for RPN2: Ribophorin II Hs.370895 [show with all ESTs]Unigene Representative Sequence: NM_0029518 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000456102 ENST00000237530(uc010gfw.2 uc021wdb.1 uc002xgq.3 uc002xgp.3)
ENST00000373622 ENST00000373632 ENST00000462163 ENST00000437329 ENST00000456400
ENST00000470352
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPN2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPN2 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RPN2 (NM_002951) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPN2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPN2 |
Additional cDNA sequence: AK096243.1 AK296126.1 AK308683.1 AK315801.1 BC002380.2 BC003560.1 BC013028.2 BC020222.1 CR456899.1 Y00282.1 24/48 DOTS entries (see all 48): DT.40255773 DT.95209031 DT.100882457 DT.100771448 DT.100882482 DT.120815062 DT.100882504 DT.100882501 DT.95375184 DT.100031922 DT.100882472 DT.100032268 DT.100656594 DT.120814919 DT.120814949 DT.100000204 DT.100882461 DT.100882464 DT.100882492 DT.100882499 DT.100882463 DT.100882477 DT.120814914 DT.87017718 24/1087 AceView cDNA sequences (see all 1087): BU174068 CB162344 BG774506 BM761038 BM840016 BQ882302 BQ682115 BM763335 BM847592 BF036307 BU180432 BQ221900 BG681886 BE795250 CB145919 AI133631 BQ689264 BP352644 AA312746 AW850075 BU859393 BE909280 BQ682155 CD358303
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for RPN2 (see all 12) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | |
| SP2: | | | - | | - | | - | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17c | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21 |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RPN2
|
Expression
for RPN2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RPN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCCAGACCT
About this image
See RPN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RPN2
SOURCE GeneReport for Unigene cluster: Hs.370895
UniProtKB/Swiss-Prot: RPN2_HUMAN, P04844Tissue specificity: Expressed in all tissues tested
SABiosciences Custom PCR Arrays for RPN2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPN2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPN2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPN2 |
Orthologs
for RPN2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RPN2 gene from 9/27 species (see all 27) About this table
ENSEMBL Gene Tree for RPN2 (if available)
TreeFam Gene Tree for RPN2 (if available) |
Paralogs
for RPN2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for RPN2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RPN2 (35806813 - 35870026 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for RPN2
1 CNV: 102962
5 Indels: 61928 46095 41894 26818 40450
Human Gene Mutation Database (HGMD): RPN2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPN2 |
|
Disorders
/ Diseases
for RPN2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RPN2 for disorders About GeneDecksing
OMIM gene information: 180490
OMIM disorders: --
16  diseases for RPN2: About MalaCardshermansky-pudlak syndrome dyserythropoietic anemia congenital dyserythropoietic anemia type 2 diabetes mellitus
microsporidiosis diabetes mellitus anemia insulinoma
hepatocellular carcinoma alzheimer's disease gastric cancer colorectal cancer
prostate cancer breast cancer prostatitis carcinoma
1 Novoseek disease relationship for RPN2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
1 |
18724378 (1) |
Human Genome Epidemiology (HuGE) Navigator: RPN2 (4 documents)
Export disorders for RPN2 gene to outside databases
|
Publications
for RPN2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RPN2 gene, integrated from 9 sources (see all 66):
(articles sorted by number of sources associating them with RPN2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1, 2 Meierhofer D.... Kaiser P. (2008)
- Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. (PubMed id 15835887)1, 2 Shibatani T.... Skach W.R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. (PubMed id 12887896)1, 2 Kelleher D.J.... Gilmore R. (2003)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Human ribophorins I and II: the primary structure and membrane topology of two highly conserved rough endoplasmic reticulum-specific glycoproteins. (PubMed id 3034581)1, 2 Crimaudo C.... Meyer D.I. (1987)
- RPN2 gene confers docetaxel resistance in breast cancer. (PubMed id 18724378)1, 9 Honma K....Ochiya T. (2008)
- Mapping of the ribophorin II (RPN II) gene to human chromosome 20q12-q13.1 by in-situ hybridization. (PubMed id 2066112)1, 9 Loffler C....Hansmann I. (1991)
|
External Searches for RPN2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RPN2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RPN2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RPN2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RPN2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RPN2 gene:
Search GeneIP for patents involving RPN2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RPN2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for RPN2 | | OriGene shRNA RFP for RPN2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPN2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPN2 | | | OriGene Protein Over-expression Lysate for RPN2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RPN2 | | OriGene 3'-UTR Clone for RPN2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPN2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPN2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RPN2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RPN2 | | OriGene Custom Protein Services for RPN2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPN2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPN2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPN2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPN2 |
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| | | | Search Tocris compounds for RPN2 |
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 | | | RPN2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPN2 |
|  |  |  |  | | | | ThermoFisher Antibodies for RPN2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPN2 |
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