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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPLP2 Gene

protein-coding   GIFtS: 59
GCID: GC11P000799

ribosomal protein, large, P2


(Previous symbol: D11S2243E)
 Explore 17 diseases affiliated with
RPLP2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPLP2    

Aliases
for RPLP2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein, Large, P21 2     Renal Carcinoma Antigen NY-REN-442 3
D11S2243E1 2 3     MGC714081
RPP21 2 3     60S Acidic Ribosomal Protein P22
LP21 2     Acidic Ribosomal Phosphoprotein P22
P21 2     

External Ids:    HGNC: 103771   Entrez Gene: 61812   Ensembl: ENSG000001776007   OMIM: 1805305   UniProtKB: P053873   

Export aliases for RPLP2 gene to outside databases

Previous GC identifers: GC11U990117 GC11M000732 GC11M000385 GC11P000801 GC11P000625


Summaries
for RPLP2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPLP2:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional
equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an
important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the
encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal
phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1
and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal
proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: RLA2_HUMAN, P05387
Function: Plays an important role in the elongation step of protein synthesis

Gene Wiki entry for RPLP2


Genomic Views
for RPLP2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_009237.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPLP2 gene promoter:
         Max1   Pax-5   p53   p300   RelA   NF-kappaB1   NF-kappaB   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPLP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPLP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPLP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

RPLP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPLP2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P000799:  view genomic region     (about GC identifiers)

Start:
 809,647 bp from pter      End:
 812,880 bp from pter
Size:
 3,234 bases      Orientation:
 plus strand

Proteins
for RPLP2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RLA2_HUMAN, P05387 (See protein sequence)
Recommended Name: 60S acidic ribosomal protein P2  
Size: 115 amino acids; 11665 Da
Subunit: P1 and P2 exist as dimers at the large ribosomal subunit
4 PDB 3D structures from and Proteopedia for RPLP2:
1S4J (3D)        2JDL (3D)        2LBF (3D)        2W1O (3D)    
Secondary accessions: Q6FG96

Explore the universe of human proteins at neXtProt for RPLP2: NX_P05387

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P05387

    • RPLP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_000995.1  
    ENSEMBL proteins: 
     ENSP00000322419   ENSP00000431240   ENSP00000433443  
    Reactome Protein details: P05387
    Human Recombinant Protein Products: 
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    Novus Biologicals RPLP2 Lysate
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    ProSpec Recombinant Protein for RPLP2
    Uscn Proteins for RPLP2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0022625cytosolic large ribosomal subunit IDA12962325


    RPLP2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RPLP2

    Protein Domains /
    Families
    for RPLP2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPLP2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001813 Ribosomal_60S

    Graphical View of Domain Structure for InterPro Entry P05387

    ProtoNet protein and cluster: P05387

    1 Blocks protein family: IPB001813 60S Acidic ribosomal protein

    UniProtKB/Swiss-Prot: RLA2_HUMAN, P05387
    Similarity: Belongs to the ribosomal protein L12P family


    Function
    for RPLP2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RLA2_HUMAN, P05387
    Function: Plays an important role in the elongation step of protein synthesis

         Genatlas biochemistry entry for RPLP2:
    60S acidic ribosomal protein P2

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: RPLP2
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS3323886
    GO:0003735structural constituent of ribosome NAS12962325


    RPLP2 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for RPLP2:
     Increased S DNA content, incre  Nuclear 40S maturation defects  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 


    Pathways & Interactions
    for RPLP2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    3Disease
    		Disease1.00
    4Generic Transcription Pathway
    		Gene Expression0.46
    5Asparagine N-linked glycosylation
    		Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPLP2
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPLP2 
        Cytoplasmic Ribosomal Proteins

    5/28        Reactome Pathways for RPLP2 (see all 28)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPLP2):
        Ribosome


    RPLP2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPLP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/283 Interacting proteins for RPLP2 (P053872, 3 ENSP000003224194) via UniProtKB, MINT, STRING, and/or I2D (see all 283)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFKB2Q006532, 3, ENSP000001894444MINT-48706 I2D: score=2 STRING: ENSP00000189444
    IKBKGQ9Y6K92, 3MINT-48147 I2D: score=2 
    MAP3K1Q132332, 3MINT-48285 I2D: score=2 
    MAP3K14Q995582, 3MINT-48796 I2D: score=2 
    RELBQ012012, 3MINT-48985 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPLP2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPLP2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RPLP2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPLP2
    1 Novoseek chemical compound relationship for RPLP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    allergens 24.1 1 10224375 (1)

    Search CenterWatch for drugs/clinical trials and news about RPLP2 / RLA2 

    Transcripts
    for RPLP2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPLP2 gene: 
    NM_001004.3  

    Unigene Cluster for RPLP2:

    Ribosomal protein, large, P2
    Hs.437594  [show with all ESTs]
    Unigene Representative Sequence: BM912995
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000321153(uc001lrq.1) ENST00000532004 ENST00000530797 ENST00000524867
    ENST00000530398 ENST00000526222 ENST00000525722 ENST00000527517

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPLP2 (see all 7)
    OriGene shRNA RFP: RPLP2
    OriGene siRNA: RPLP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPLP2
    Clone
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    GenScript: all cDNA clones in your preferred vector: RPLP2 (NM_001004)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPLP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPLP2

    Additional cDNA sequence: 

    AK130959.1 AK311954.1 BC005354.1 BC005920.1 BC007573.1 BC062314.1 CR542212.1 CR542248.1 
    M17887.1 

    24/48 DOTS entries (see all 48):

    DT.85102943  DT.100868243  DT.100871031  DT.100708269  DT.100043128  DT.95200484  DT.120711448  DT.100708290 
    DT.87005958  DT.91973249  DT.95215346  DT.100708261  DT.95101595  DT.120711552  DT.100856378  DT.87007877 
    DT.70104753  DT.100761040  DT.120910227  DT.87077768  DT.91708148  DT.97766178  DT.100708258  DT.100708285 

    24/1400 AceView cDNA sequences (see all 1400):

    AJ705234 CD677425 AA359773 AA310670 BU845108 BI225677 BM854920 AA320289 
    CD722991 BG179350 F29706 BQ653361 BQ084104 CR595853 BU538287 F24349 
    BE263190 AI708358 BM894289 NM_001004 AI217930 F18824 BM706832 CD678342 

    GeneLoc Exon Structure


    Expression
    for RPLP2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPLP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGATTTGGCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPLP2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm-like cells (Generation of hepato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPLP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPLP2

    SOURCE GeneReport for Unigene cluster: Hs.437594
        SABiosciences Custom PCR Arrays for RPLP2
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    In Situ
    Assay Products:     
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    Orthologs
    for RPLP2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPLP2 gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves RPLP21 ribosomal protein, large, P2 81.16(n)
    86.09(a)    		   426492  XM_424134.3  XP_424134.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPLP26
    		 --
    		 85(a)
    		 1 ↔ 1
    		 1(73745807-73752469)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.247182 Xenopus laevis transcribed sequence with weak similarity more 78.27(n)    BJ074671.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.267912 Danio rerio cDNA clone MGC73372 IMAGE4199035, complete more 75.09(n)    BC059681.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpLP21 Ribosomal protein LP2 63.13(n)
    61.06(a)    		   36855  NM_206135.1  NP_995857.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea C37A2.71 Protein C37A2.7 60.44(n)
    59.81(a)    		   172401  NM_059543.4  NP_491944.2 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes RPP2B(YDR382W)4
    RPP2B1    		 Ribosomal protein P2 beta, a component of the ribosomal more4
    Rpp2bp1    		 59.33(n)1
    59.63(a)1    		   4(1239492-1239824)4
    8519901, 4  NP_010670.31  NP_010670.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G277106
    AT3G445906
    (see all 5)    		 60S acidic ribosomal protein P2-4
    (see all 5)    		 48(a)
    45(a)
    (see all 5)    		 1 ↔ many
    1 ↔ many
    (see all 5)    		 2(11816634-11817867)
    3(16163817-16164931)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 6)    		 60S acidic ribosomal protein, putative, expressed
    (see all 6)    		 58(a)
    49(a)
    (see all 6)    		 1 ↔ many
    1 ↔ many
    (see all 6)    		 5(21772857-21775125)
    2(19449254-19452482)


    ENSEMBL Gene Tree for RPLP2 (if available)
    TreeFam Gene Tree for RPLP2 (if available) 

    Paralogs
    for RPLP2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPLP2 gene

    RPLP2 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for RPLP2
    PGOHUM00000239727 PGOHUM00000237467 PGOHUM00000235438 PGOHUM00000243534


    Genomic Variants
    for RPLP2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/125 NCBI SNPs in RPLP2 are shown (see all 125)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1113203361,2
    		C,--808124(+) ATAATA/-AAAAA 1 -- us2k11Minor allele frequency- -:0.00CSA 2
    rs710229771,2
    		C--808127(+) AAAAAA/-GTGAG 1 -- us2k11Minor allele frequency- -:0.00NA 2
    rs1884738231,2
    		--808246(+) ACATGA/GTGAAA 1 -- us2k10--------
    rs749942111,2
    		C,--808257(+) CCCCGC/TCTGTA 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs793267171,2
    		C,--808416(+) TGGGAC/GTCCTC 1 -- us2k13Minor allele frequency- G:0.23CSA WA EA 240
    rs286946341,2
    		C,F,--808423(+) CCTCAA/GAAAAA 1 -- us2k1 trp310Minor allele frequency- G:0.31NA WA CSA EA 371
    rs1812748381,2
    		--808480(+) TCCCAA/GCACTT 1 -- us2k10--------
    rs578942861,2
    		C,--808549(+) AATTT-/TAGCCG 1 -- us2k10--------
    rs615397931,2
    		--808554(+) TTTTAG/TCCGGG 1 -- us2k10--------
    rs65979801,2
    		C,H--808556(-) CACCCC/GGCTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPLP2 (809647 - 812880 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for RPLP2
         6 CNVs: 29886 30530 3831 29883 29885 4726

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    Disorders / Diseases
    for RPLP2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPLP2 for disorders           About GeneDecksing

    OMIM gene information: 180530    OMIM disorders: --

    17 diseases for RPLP2:    About MalaCards
    diamond-blackfan anemia    renal carcinoma    carcinoma    lupus erythematosus
    mouth disease    systemic lupus erythematosus    babesiosis    cysticercosis
    renal cell carcinoma    anemia    glomerulonephritis    hepatocellular carcinoma
    pancreatic diseases    colorectal cancer    osteosarcoma    pancreatitis
    malaria

    1 disease from the University of Copenhagen DISEASES database for RPLP2:
    Diamond-Blackfan anemia

    2 Novoseek disease relationships for RPLP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lupus erythematosus systemic 17.1 1 7913711 (1)
    tumors 0 1 20385220 (1)


    Export disorders for RPLP2 gene to outside databases

    Publications
    for RPLP2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPLP2 gene, integrated from 9 sources (see all 85):
    (articles sorted by number of sources associating them with RPLP2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. (PubMed id 3323886)1, 2, 3 Rich B.E. and Steitz J.A. (1987)
    2. Solution structure of the dimerization domain of ribo somal protein P2 provides insights for the structural organization of eukaryoti c stalk. (PubMed id 20385603)1, 2 Lee K.M....Wong K.B. (2010)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. Identification and characterization of phosphorylated proteins in the human pituitary. (PubMed id 14997482)1, 2 Giorgianni F.... Desiderio D.M. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    8. Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2 Scanlan M.J....Old L.J. (1999)
    9. Human liver protein map: a reference database established by microsequencing and gel comparison. (PubMed id 1286669)1, 2 Hochstrasser D.F.... Hughes G.J. (1992)
    10. A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2. (PubMed id 2153399)1, 2 Sharp M.G.F....Varley J.M. (1990)

    External Searches for RPLP2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RPLP2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6181 HGNC: 10377 AceView: RPLP2 Ensembl:ENSG00000177600 euGenes: HUgn6181
    ECgene: RPLP2 Kegg: 6181 H-InvDB: RPLP2

    Other Databases showing RPLP2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPLP2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPLP2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPLP2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPLP2 gene:
    Search GeneIP for patents involving RPLP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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