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RPLP1 Gene

protein-coding   GIFtS: 60
GCID: GC15P069745

Ribosomal Protein, Large, P1

Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein, Large, P11 2     RPP12
60S Acidic Ribosomal Protein P12     Acidic Ribosomal Phosphoprotein P12
LP12     RRP13
P12     

External Ids:    HGNC: 103721   Entrez Gene: 61762   Ensembl: ENSG000001378187   OMIM: 1805205   UniProtKB: P053863   

Export aliases for RPLP1 gene to outside databases

Previous GC identifers: GC15P065586 GC15P062843 GC15P067324 GC15P067460 GC15P067532 GC15P046578


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPLP1 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a
functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins.
It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are
basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the
ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex
consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively
spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding
ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. (provided
by RefSeq, Jul 2008)

GeneCards Summary for RPLP1 Gene:
RPLP1 (ribosomal protein, large, P1) is a protein-coding gene. Diseases associated with RPLP1 include pandas, and mouth disease. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

UniProtKB/Swiss-Prot: RLA1_HUMAN, P05386
Function: Plays an important role in the elongation step of protein synthesis

Gene Wiki entry for RPLP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPLP1 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   GATA-2   GATA-1   PPAR-gamma1   E2F   E2F-1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPLP1 promoter sequence
   Search Chromatin IP Primers for RPLP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPLP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22   Ensembl cytogenetic band:  15q23   HGNC cytogenetic band: 15q22

RPLP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPLP1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P069745:  view genomic region     (about GC identifiers)

Start:
69,745,123 bp from pter      End:
69,748,255 bp from pter
Size:
3,133 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RLA1_HUMAN, P05386 (See protein sequence)
Recommended Name: 60S acidic ribosomal protein P1  
Size: 114 amino acids; 11514 Da
Subunit: Heterodimer with RPLP2 at the lateral ribosomal stalk of the large ribosomal subunit
3 PDB 3D structures from and Proteopedia for RPLP1:
2LBF (3D)        3J3B (3D)        4BEH (3D)    
Secondary accessions: A6NIB2
Alternative splicing: 2 isoforms:  P05386-1   P05386-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPLP1: NX_P05386

Explore proteomics data for RPLP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RPLP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_000994.1  NP_998890.1  

    ENSEMBL proteins: 
     ENSP00000346037   ENSP00000350437   ENSP00000453067  
    Reactome Protein details: P05386

    RPLP1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    2 InterPro protein domains:
     IPR001813 Ribosomal_L10/L12
     IPR027534 Ribosomal_L12

    Graphical View of Domain Structure for InterPro Entry P05386

    ProtoNet protein and cluster: P05386

    1 Blocks protein domain: IPB001813 60S Acidic ribosomal protein

    UniProtKB/Swiss-Prot: RLA1_HUMAN, P05386
    Similarity: Belongs to the ribosomal protein L12P family


    RPLP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RLA1_HUMAN, P05386
    Function: Plays an important role in the elongation step of protein synthesis

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS3323886
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding IPI12054647
         
    RPLP1 for ontologies           About GeneDecksing


    Phenotypes:
         5 GenomeRNAi human phenotypes for RPLP1:
     Decreased viability of wild-ty  Increased S DNA content, incre  Nuclear 40S maturation defects  Nuclear 60S biogenesis defects 
     Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPLP1
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    miRNA
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    miRTarBase miRNAs that target RPLP1:
    hsa-mir-204-5p (MIRT047014), hsa-mir-320a (MIRT044726), hsa-mir-423-3p (MIRT042584), hsa-mir-296-3p (MIRT038374), hsa-mir-100-5p (MIRT048543), hsa-mir-186-5p (MIRT044994), hsa-mir-26b-5p (MIRT029812), hsa-mir-1180-3p (MIRT035944), hsa-mir-3188 (MIRT052811), hsa-mir-92a-3p (MIRT049385), hsa-mir-16-5p (MIRT031818), hsa-mir-32-5p (MIRT049854), hsa-mir-877-5p (MIRT037205), hsa-mir-744-5p (MIRT037548), hsa-mir-324-3p (MIRT042894), hsa-mir-3605-3p (MIRT052847)

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    GenScript: all cDNA clones in your preferred vector (see all 2): RPLP1 (NM_213725)
    Sino Biological Human cDNA Clone for RPLP1
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    cytoskeleton1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325

    RPLP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPLP1 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPLP1
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPLP1
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPLP1 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPLP1):
        Ribosome


    RPLP1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPLP1
    Interactions:

        Search GeneGlobe Interaction Network for RPLP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPLP1 (P053862, 3 ENSP000003460374) via UniProtKB, MINT, STRING, and/or I2D (see all 348)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPLP2P053872, 3, ENSP000003224194MINT-8391384 MINT-8391451 I2D: score=2 STRING: ENSP00000322419
    ATP5J2P561342, 3, ENSP000002924754MINT-63893 I2D: score=5 STRING: ENSP00000292475
    NUDT21O438092, 3MINT-64642 MINT-8264501 I2D: score=5 
    NUDT3O959892, 3MINT-63330 MINT-8265004 I2D: score=5 
    PFDN1O609252, 3, ENSP000002618134MINT-63189 I2D: score=5 STRING: ENSP00000261813
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPLP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPLP1 (RLA1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPLP1 gene (2 alternative transcripts): 
    NM_001003.2  NM_213725.1  

    Unigene Cluster for RPLP1:

    Ribosomal protein, large, P1
    Hs.356502  [show with all ESTs]
    Unigene Representative Sequence: BQ278494
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000260379(uc002asd.1) ENST00000357790(uc002ase.1) ENST00000487304
    ENST00000560274 ENST00000488122
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    Additional mRNA sequence: 

    AK026579.1 AK130958.1 AK311456.1 AY303789.1 BC003369.1 BC007590.1 CR450339.1 CR542209.1 
    D28366.1 M17886.1 

    Selected DOTS entries (see all 71):

    DT.87001765  DT.97769604  DT.100859183  DT.100721118  DT.100721126  DT.453699  DT.100721114  DT.102844025 
    DT.75121595  DT.100858352  DT.97769623  DT.99982848  DT.121038870  DT.95335278  DT.121038882  DT.95086063 
    DT.121038897  DT.99925894  DT.100653841  DT.100721112  DT.121038977  DT.87017943  DT.121038984  DT.91651891 

    Selected AceView cDNA sequences (see all 2388):

    BM542463 BU783682 BM845619 AU133480 BU147129 BM802556 BM817604 AI581503 
    AI752933 BU077639 F29332 AI720382 BU071080 BM894274 BM876235 F29606 
    BM663403 AI749889 BI857175 BM450427 BM746632 BQ637163 BM663245 BQ637189 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for RPLP1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4
    SP1:                                    
    SP2:              -                     


    ECgene alternative splicing isoforms for RPLP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPLP1 expression in normal human tissues (normalized intensities)      RPLP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RPLP1 Expression
    About this image


    RPLP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 21) fully expand
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
    RPLP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPLP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.356502
        Custom PCR Arrays for RPLP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPLP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RPLP1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rplp15 ribosomal protein, large, P1   --   9 (33.50 cM) 61913283 
    chicken
    (Gallus gallus)
    Aves RPLP11 ribosomal protein, large, P1 80.41(n)
    85.96(a)
      396262  NM_205322.1  NP_990653.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPLP16
    ribosomal protein, large, P1
    89(a)
    1 ↔ 1
    4(15614195-15617737)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.208332 Xenopus laevis transcribed sequence with strong similarity more 88.72(n)    BX852692.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa93f022 wufa93f02 79.74(n)   336719  BC062852.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpLP16
    Ribosomal protein LP1
    63(a)
    1 ↔ 1
    2L(419952-420864)
    worm
    (Caenorhabditis elegans)
    Secernentea rla-16
    Protein RLA-1 (rla-1) mRNA, complete cds
    65(a)
    1 ↔ 1
    I(2069041-2069587) WBGene00004409


    ENSEMBL Gene Tree for RPLP1 (if available)
    TreeFam Gene Tree for RPLP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPLP1 gene

    RPLP1 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPLP1 (see all 18)
    PGOHUM00000238496 PGOHUM00000248142 PGOHUM00000248236 PGOHUM00000262045 PGOHUM00000237078


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPLP1 (see all 133)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
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    ----------
    rs2006058621,2
    C--69743206(+) AGCCT-/GGGGGGA 2 -- us2k10--------
    rs1139911511,2
    C,F--69743227(+) AACTCC/TGTCTC 2 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1806989331,2
    --69743244(+) AAAAAA/TTTTTT 2 -- us2k10--------
    rs1860500551,2
    --69743245(+) AAAAAA/TTTTTT 2 -- us2k10--------
    rs1513058711,2
    C--69743416(+) ACTTC-/TCTTGA 2 -- us2k10--------
    rs767726031,2
    C,F--69743551(+) TTTTTT/CTGAGA 2 -- us2k12Minor allele frequency- C:0.12NA EA 240
    rs284368191,2
    --69743622(+) CCTCCC/GCCTCC 2 -- us2k10--------
    rs1912945661,2
    --69743728(+) AGACAA/GGGTTT 2 -- us2k10--------
    rs80337901,2
    C,F,H--69743838(+) cggcAG/AATCAG 2 -- us2k16Minor allele frequency- A:0.02NS EA WA 532
    rs1825881751,2
    --69744029(+) TTTTTA/TAAAAA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPLP1 (69745123 - 69748255 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RPLP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1585CNV Insertion18451855
    nsv520964CNV Gain19592680
    dgv753e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 180520    OMIM disorders: --

    10 diseases for RPLP1:    About MalaCards
    pandas    mouth disease    rhabdomyosarcoma    influenza
    chronic lymphocytic leukemia    rheumatoid arthritis    arthritis    malaria
    breast cancer    leukemia


    RPLP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPLP1

    Export disorders for RPLP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPLP1 gene, integrated from 10 sources (see all 77):
    (articles sorted by number of sources associating them with RPLP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of phosphorylated proteins in the human pituitary. (PubMed id 14997482)1, 2, 9 Giorgianni F.... Desiderio D.M. (Proteomics 2004)
    2. Phosphoproteomic analysis of the human pituitary. (PubMed id 16807684)1, 2 Beranova-Giorgianni S.... Giorgianni F. (Pituitary 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (Genome Res. 2002)
    5. Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. (PubMed id 3323886)1, 2 Rich B.E. and Steitz J.A. (Mol. Cell. Biol. 1987)
    6. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    7. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. (PubMed id 23798571)1 Roy S.J....Parent J.L. (Mol. Endocrinol. 2013)
    10. Significance of antibodies against the native ribosomal P protein complex and recombinant P0, P1, and P2 proteins in the diagnosis of Chinese patients with systemic lupus erythematosus. (PubMed id 23400861)1 Li J....Li Z.G. (J. Clin. Lab. Anal. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 6176 HGNC: 10372 AceView: RPLP1andKIF23 Ensembl:ENSG00000137818 euGenes: HUgn6176
    ECgene: RPLP1 Kegg: 6176 H-InvDB: RPLP1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPLP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RPLP1 gene:
    Search GeneIP for patents involving RPLP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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