RPLP0P6 Gene
pseudogene GIFtS: 26
GCID: GC02P038709
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ribosomal protein, large, P0 pseudogene 6
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Aliases
for RPLP0P6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ribosomal Protein, Large, P0 Pseudogene 61 2 | | RPLP0_2_2092 |
Export aliases for RPLP0P6 gene to outside databasesPrevious GC identifer: GC02P038553 |
Summaries
for RPLP0P6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: RLA0L_HUMAN, Q8NHW5Function: Ribosomal protein P0 is the functional equivalent of E.coli protein L10 (By similarity)
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Genomic Views
for RPLP0P6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for RPLP0P6
Other transcription factors
Search SABiosciences Chromatin IP Primers for RPLP0P6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPLP0P6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p22.1 Ensembl cytogenetic band: 2p22.1 HGNC cytogenetic band: 2p22.1RPLP0P6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P038709: view genomic region
(about GC identifiers)
Start:
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38,708,916 bp from pter |
End:
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38,710,017 bp from pter |
Size:
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1,102 bases |
Orientation:
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plus strand |
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Proteins
for RPLP0P6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RLA0L_HUMAN, Q8NHW5 (See
protein sequence)Recommended Name: 60S acidic ribosomal protein P0-like Size: 317 amino acids; 34364 Da
Subunit: P0 forms a pentameric complex by interaction with dimers of P1 and P2 (By similarity)
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for RPLP0P6: NX_Q8NHW5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NHW5
RPLP0P6 Protein expression data from MOPED and PaxDb: About this image 
Human Recombinant Protein Products for RPLP0P6:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RPLP0P6 for ontologies About GeneDecksing
RPLP0P6 Antibody Products:
Assay Products for RPLP0P6: |
Protein
Domains /
Families
for RPLP0P6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPLP0P6 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NHW5ProtoNet protein and cluster: Q8NHW5 1 Blocks protein family: IPB001813 60S Acidic ribosomal protein
UniProtKB/Swiss-Prot: RLA0L_HUMAN, Q8NHW5Similarity: Belongs to the ribosomal protein L10P family |
Function
for RPLP0P6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RLA0L_HUMAN, Q8NHW5Function: Ribosomal protein P0 is the functional equivalent of E.coli protein L10 (By similarity) Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
IEA | -- |
RPLP0P6 for ontologies About GeneDecksing
Animal Models:
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Pathways & Interactions
for RPLP0P6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPLP0P6
5/13 Interacting proteins for RPLP0P6 (Q8NHW52, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006414 | translational elongation |
IEA | -- | | GO:0042254 | ribosome biogenesis |
IEA | -- |
RPLP0P6 for ontologies About GeneDecksing
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Drugs & Compounds
for RPLP0P6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RPLP0P6
Search CenterWatch for drugs/clinical trials and news about RPLP0P6 
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Transcripts
for RPLP0P6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000394878 ENST00000413306
24/8667 AceView cDNA sequences (see all 8667): BF933979 AA360568 CR607008 CR599753 AA378984 AJ715036 CR619170 CR609713 BE693899 CR619526 CR606552 CR623941 BE711243 CR611006 CR595846 CR613558 CR617647 CR616602 CR602867 CR605461 CR623258 BE073632 CR604842 CR599619
GeneLoc Exon Structure
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Expression
for RPLP0P6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RPLP0P6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RPLP0P6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RPLP0P6
SABiosciences Custom PCR Arrays for RPLP0P6
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RPLP0P6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPLP0P6 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPLP0P6 |
Orthologs
for RPLP0P6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for RPLP0P6 gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
MGC757712 |
hypothetical protein MGC75771 |
82.06(n) |
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BC061299.1 |
Species with no ortholog for RPLP0P6
ENSEMBL Gene Tree for RPLP0P6 (if available)
TreeFam Gene Tree for RPLP0P6 (if available) |
Paralogs
for RPLP0P6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for RPLP0P6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for RPLP0P6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RPLP0P6 for disorders About GeneDecksing
1  disease for RPLP0P6: About MalaCardsmyeloma
Export disorders for RPLP0P6 gene to outside databases
|
Publications
for RPLP0P6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RPLP0P6 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RPLP0P6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Comparative analysis of processed ribosomal protein p seudogenes in four mammalian genomes. (PubMed id 19123937)1, 3 Balasubramanian S....Gerstein M. (2009)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Identification of ubiquitinated proteins from human m ultiple myeloma U266 cells by proteomics. (PubMed id 22108332)1 Jia H....He Q. (2011)
- Identification of SUMOylated proteins in neuroblastoma cells after treatment with hydrogen peroxide or ascorbate. (PubMed id 21110914)1 Grant M.M. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
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External Searches for RPLP0P6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RPLP0P6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing RPLP0P6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RPLP0P6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for RPLP0P6 gene:
Search GeneIP for patents involving RPLP0P6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RPLP0P6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPLP0P6 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPLP0P6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPLP0P6 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPLP0P6 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPLP0P6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPLP0P6 |
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| | | | Search Tocris compounds for RPLP0P6 |
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 | | | | |  |  |  |  | | | | Search ThermoFisher Antibodies for RPLP0P6 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RPLP0P6 |
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