Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL9 Gene

protein-coding   GIFtS: 59
GCID: GC04M039457

Ribosomal Protein L9
Microbiology & Infectious Diseases Congress
  See related diseases
at
MalaCards
 

Aliases
for RPL9 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section
Aliases
Ribosomal Protein L91 2
60S Ribosomal Protein L92
L92
NPC-A-162

External Ids:    HGNC: 103691   Entrez Gene: 61332   Ensembl: ENSG000001636827   OMIM: 6036865   UniProtKB: P329693   

Export aliases for RPL9 gene to outside databases

Previous GC identifers: GC04M039630 GC04M039290 GC04M039352 GC04M039278 GC04M039131 GC04M038780


Summaries
for RPL9 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPL9 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of
ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there
are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced
transcript variants encoding the same protein have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL9 Gene: 
RPL9 (ribosomal protein L9) is a protein-coding gene. Diseases associated with RPL9 include diamond-blackfan anemia, and anemia, and among its related super-pathways are Viral mRNA Translation. GO annotations related to this gene include RNA binding and rRNA binding.

Gene Wiki entry for RPL9 Gene


Genomic Views
for RPL9 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016297.16  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL9 gene promoter:
         ER-alpha   PPAR-gamma1   AML1a   PPAR-gamma2   Nkx2-5   Gfi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPL9 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p13   Ensembl cytogenetic band:  4p14   HGNC cytogenetic band: 4p13

RPL9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL9 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M039457:  view genomic region     (about GC identifiers)

Start:
 39,455,744 bp from pter      End:
 39,460,568 bp from pter
Size:
 4,825 bases      Orientation:
 minus strand

Proteins
for RPL9 gene

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section
UniProtKB/Swiss-Prot: RL9_HUMAN, P32969 (See protein sequence)
Recommended Name: 60S ribosomal protein L9  
Size: 192 amino acids; 21863 Da
2 PDB 3D structures from and Proteopedia for RPL9:
2CQL (3D)        3J3B (3D)    

Explore the universe of human proteins at neXtProt for RPL9: NX_P32969

Explore proteomics data for RPL9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P32969

    • RPL9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPL9 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_000652.2  NP_001020092.1  

    ENSEMBL proteins: 
     ENSP00000346022   ENSP00000400467   ENSP00000425250   ENSP00000424796   ENSP00000421872  
     ENSP00000422191  
    Reactome Protein details: P32969
    Human Recombinant Protein Products for RPL9: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for RPL9
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for RPL9
    GenScript Custom Purified and Recombinant Proteins Services for RPL9
    Novus Biologicals RPL9 Proteins
    Novus Biologicals RPL9 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPL9 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome TAS8597601
    GO:0022625cytosolic large ribosomal subunit IDA12962325

    RPL9 for ontologies           About GeneDecksing



    RPL9 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RPL9
    GenScript Custom Superior Antibodies Services for RPL9
    Novus Biologicals RPL9 Antibodies
    Abcam antibodies for RPL9
    Cloud-Clone Corp. Antibodies for RPL9 
    ThermoFisher Antibody for RPL9
    LSBio Antibodies in human, mouse, rat for RPL9 

    Assay Products for RPL9: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RPL9
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPL9
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RPL9 
    Cloud-Clone Corp. CLIAs for RPL9

    Protein Domains /
    Families
    for RPL9 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    		 HGNC Gene Families: 
    RPL: L ribosomal proteins

    3 InterPro protein domains:
     IPR000702 Ribosomal_L6
     IPR002359 Ribosomal_L6_CS2
     IPR020040 Ribosomal_L6_a/b-dom

    Graphical View of Domain Structure for InterPro Entry P32969

    ProtoNet protein and cluster: P32969

    1 Blocks protein domain: IPB002359 Ribosomal protein L6

    UniProtKB/Swiss-Prot: RL9_HUMAN, P32969
    Similarity: Belongs to the ribosomal protein L6P family


    RPL9 for domains           About GeneDecksing


    Function
    for RPL9 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section
    Molecular Function:
         Genatlas biochemistry entry for RPL9:
    ribosomal protein L9

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS8597601
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0019843rRNA binding IEA--
         
    RPL9 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RPL9:
     Decreased viability of wild-ty  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPL9 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RPL9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL9 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL9 

    miRNA
    Products:            		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL9
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RPL9:
    hsa-miR-551b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RPL9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL9

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RPL9
    Sirion Biotech Customized adenovirus for overexpression of RPL9

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for RPL9 (see all 13)
    OriGene ORF clones in mouse, rat for RPL9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for RPL9
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL9
    Sirion Biotech Customized lentivirus for stable overexpression of RPL9 
                         Customized lentivirus expression plasmids for stable overexpression of RPL9 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for RPL9
    Search LifeMap BioReagents cell lines for RPL9
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL9


    Pathways & Interactions
    for RPL9 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPL9 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    		CFTR translational fidelity (class I mutations)0.83
    		Ribosome0.59
    		Cytoplasmic Ribosomal Proteins0.65

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL9
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL9
        Cytoplasmic Ribosomal Proteins

    5/23        Reactome Pathways for RPL9 (see all 23)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL9):
        Ribosome


    RPL9 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/331 Interacting proteins for RPL9 (P329692, 3 ENSP000003460224) via UniProtKB, MINT, STRING, and/or I2D (see all 331)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS3P233962, 3, ENSP000002785724MINT-6542674 I2D: score=4 STRING: ENSP00000278572
    SORBS2O948752, 3, ENSP000002847764MINT-63671 I2D: score=4 STRING: ENSP00000284776
    MOCS2O960332, 3MINT-63672 I2D: score=1 I2D: score=3 
    RPL5P467772, 3, ENSP000003593454MINT-6542674 I2D: score=1 STRING: ENSP00000359345
    RPL8P629172, 3, ENSP000002625844MINT-6542674 I2D: score=1 STRING: ENSP00000262584
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL9 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPL9 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RPL9 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPL9 (RL9)

    3 Novoseek inferred chemical compound relationships for RPL9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    urea 48.2 2 15890362 (1), 18707127 (1)
    guanidine hydrochloride 38.7 2 10769155 (1)
    amide 25.1 1 16834323 (1)

    Search CenterWatch for drugs/clinical trials and news about RPL9 / RL9

    Transcripts
    for RPL9 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPL9 gene (2 alternative transcripts): 
    NM_000661.4  NM_001024921.2  

    Unigene Clusters for RPL9:

    Ribosomal protein L9
    Hs.412370  [show with all ESTs], Hs.513083  [show with all ESTs], Hs.730597  [show with all ESTs]
    Unigene Representative Sequences: BM455207, BQ057285, CD388526
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000295955(uc003guc.3 uc011byk.2) ENST00000503277 ENST00000449470(uc003gub.3)
    ENST00000508595 ENST00000511643 ENST00000506581 ENST00000514842 ENST00000503040
    ENST00000504470 ENST00000511075(uc011byl.1) ENST00000437992(uc003gud.1)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:             		 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL9
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RPL9:
    hsa-miR-551b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RPL9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL9
    Clone
    Products:             		 OriGene clones in human, mouse for RPL9 (see all 13)
    OriGene ORF clones in mouse, rat for RPL9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for RPL9
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL9
    Sirion Biotech Customized lentivirus for stable overexpression of RPL9 
                         Customized lentivirus expression plasmids for stable overexpression of RPL9 
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for RPL9
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL9
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RPL9
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL9

    Additional mRNA sequence: 

    AB062431.1 AK312241.1 BC000483.2 BC004156.2 BC004206.2 BC007967.2 BC012149.1 BC031906.1 
    BC066318.1 BC070214.1 U09953.1 

    24/115 DOTS entries (see all 115):

    DT.95368454  DT.92324133  DT.100742904  DT.100865537  DT.100862674  DT.99926501  DT.100742876  DT.91782393 
    DT.102843796  DT.121022052  DT.75112970  DT.100742863  DT.100862052  DT.121021769  DT.91782433  DT.95368581 
    DT.91782369  DT.102831161  DT.121021500  DT.102826574  DT.95368649  DT.91726121  DT.97852590  DT.100742894 

    24/2298 AceView cDNA sequences (see all 2298):

    AA322587 BU528659 AA969511 BE378735 AU133456 H63517 BM664298 BU501386 
    AA083356 BM558501 BM458093 CF129631 AA470759 BQ181555 BQ052784 BQ919130 
    BM423677 BM989240 CB107940 BM465900 BG034036 CA406839 BG437165 BM841336 

    GeneLoc Exon Structure


    Expression
    for RPL9 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCAAGGGTG
    RPL9 Expression
    About this image


    See RPL9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL9

    SOURCE GeneReport for Unigene clusters: Hs.412370 Hs.513083 Hs.730597
        SABiosciences Custom PCR Arrays for RPL9
    Primer
    Products:    		OriGene qPCR primer pairs and template standards for RPL9
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL9
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RPL9
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL9
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL9
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL9

    Orthologs
    for RPL9 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL9 gene from 10/29 species (see all 29)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rpl91 , 5 ribosomal protein L91, 5 89.93(n)1
    98.96(a)1    		   5 (33.66 cM)5
    200051  NM_011292.21  NP_035422.11 
     653883645 
    chicken
    (Gallus gallus)    		 Aves RPL91 ribosomal protein L9 81.77(n)
    94.79(a)    		   425468  XM_003641246.1  XP_003641294.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPL96
    		 Uncharacterized protein
    		 95(a)
    		 1 ↔ 1
    		 5(99645713-99649693)
    African clawed frog
    (Xenopus laevis)    		 Amphibia rpl9-prov2 ribosomal protein L9 82.6(n)    BC046581.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.248102 Danio rerio ribosomal protein L9 mRNA, partial cds 76.08(n)    AY141976.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpL91 , 3 protein biosynthesis structural
    constituent of ribosome less3
    Ribosomal protein L91    		 65(a)3
    61.8(n)1
    65.95(a)1    		   2 32C53
    345261  NM_057813.31  NP_477161.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea rpl-91 , 3 Ribosomal protein L93
    Protein RPL-91    		 62(a)3
    58.38(n)1
    63.49(a)1    		   III(7643793-7644645)3
    1760711  NM_066259.41  NP_498660.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes RPL9B(YNL067W)4
    RPL9B1    		 Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins less4
    Rpl9bp1    		 57.66(n)1
    51.35(a)1    		   14(499681-500256)4
    8556581, 4  NP_014332.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT4G104501 60S ribosomal protein L9-2 58.82(n)
    58.29(a)    		   826637  NM_117113.3  NP_192783.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.49822 Oryza sativa (japonica cultivar-group) mRNA for ribosomal protein L9, partial cds less 76.57(n)    AK062502.1 


    ENSEMBL Gene Tree for RPL9 (if available)
    TreeFam Gene Tree for RPL9 (if available)

    Paralogs
    for RPL9 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL9 gene
    3 SIMAP similar genes for RPL9 using alignment to 7 protein entries:     RL9_HUMAN (see all proteins):
    RPL9P7    RPL9P8    RPL9P9

    RPL9 for paralogs           About GeneDecksing


    5/32 Pseudogenes.org Pseudogenes for RPL9 (see all 32)
    PGOHUM00000238440 PGOHUM00000242647 PGOHUM00000242829 PGOHUM00000239907 PGOHUM00000247758


    Genomic Variants
    for RPL9 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/93 SNPs in RPL9 are shown (see all 93)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 4 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs22495631,2
    		C,F,A,H--39455378(+) TAAAAG/ACAAGT 2 -- ds500124Minor allele frequency- A:0.35NS EA NA WA CSA 2497
    rs800141421,2
    		C,F--39455429(+) TTATTG/AAGACC 2 -- ds50012Minor allele frequency- A:0.04EA NS 270
    rs1426047691,2
    		C--39455468(+) TCTAAC/TTGATG 2 -- ds50011Minor allele frequency- T:0.01NS 150
    rs1897354191,2
    		--39455501(+) TCAGCC/TGTTTC 2 -- ds50010--------
    rs1455796421,2
    		--39455502(+) CAGCTA/GTTTCT 2 -- ds50010--------
    rs1154769921,2
    		C,F--39455727(+) ACTAGC/TTAAAA 2 -- ds50012Minor allele frequency- T:0.02WA NS 268
    rs1488756701,2
    		--39455740(+) GATAAC/TCGGTT 2 -- ds50010--------
    rs175101421,2
    		C,F,H--39455742(+) TAACCA/GGTTTA 2 -- ds5001 ese319Minor allele frequency- N:0.00NA EA NS 2174
    rs1435199001,2
    		--39455803(+) AAGTAC/GGTCTT 2 -- ut310--------
    rs1390379221,2
    		C--39455843(+) CAGGT-/AAACTG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for RPL9 (39455744 - 39460568 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RPL9:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv878942CNV Loss21882294
    nsv878943CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL9
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL9

    Disorders / Diseases
    for RPL9 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		 OMIM gene information: 603686    OMIM disorders: --

    5 diseases for RPL9:    About MalaCards
    diamond-blackfan anemia    anemia    influenza    gastric cancer
    breast cancer


    RPL9 for disorders           About GeneDecksing


    Export disorders for RPL9 gene to outside databases

    Publications
    for RPL9 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL9 gene, integrated from 9 sources (see all 77):
    (articles sorted by number of sources associating them with RPL9)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural organization and chromosomal localization of the human ribosomal protein L9 gene. (PubMed id 8597601)1, 2, 3, 9 Mazuruk K.... Rodriguez I.R. (1996)
    2. A new human ribosomal protein sequence, homologue of rat L9. (PubMed id 8415001)1, 2, 3 Hori N....Matsubara K. (1993)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2 Kenmochi N.... Page D.C. (1998)
    5. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....Yanez-Mo M. (2013)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. The P-body component USP52/PAN2 is a novel regulator o f HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Proteomic analysis of a4b1 integrin adhesion complexes reveals a-subunit-dependent protein recruitment. (PubMed id 22623428)1 Byron A....Humphries M.J. (2012)
    10. SGTA recognizes a noncanonical ubiquitin-like domain i n the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degra dation. (PubMed id 23246001)1 Xu Y....Ye Y. (2012)

    External Searches for RPL9 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RPL9 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6133 HGNC: 10369 AceView: RPL9 Ensembl:ENSG00000163682 euGenes: HUgn6133
    ECgene: RPL9 Kegg: 6133 H-InvDB: RPL9

    Other Databases showing RPL9 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPL9 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL9 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPL9 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPL9 gene:
    Search GeneIP for patents involving RPL9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for RPL9 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RPL9  
     OriGene qPCR primer pairs and template standards for RPL9   OriGene Protein Over-expression Lysate for RPL9  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RPL9  
     OriGene qSTAR qPCR primer pairs in human, mouse for RPL9   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RPL9   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPL9   OriGene Custom Protein Services for RPL9  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPL9
     QIAGEN SeqTarget long-range PCR primers for resequencing RPL9
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL9
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL9
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL9
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL9
     GenScript Custom Purified and Recombinant Proteins Services for RPL9 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for RPL9
     GenScript Custom Assay Services for RPL9 GenScript Custom Superior Antibodies Services for RPL9
     GenScript Custom overexpressing Cell Line Services for RPL9 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RPL9 promoter
     Search Chromatin IP Primers for RPL9
     RT2 qPCR Primer Assay in human, mouse / rat RPL9
     Search GNC Networks for RPL9
     SABiosciences Custom PCR Arrays for RPL9
     Search Tocris compounds for RPL9 (RL9)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RPL9 antibodies
     RPL9 proteins
     RPL9 lysates
     Antibodies for RPL9
     See all of Abcam's Antibodies, Kits and Proteins for RPL9
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for RPL9
     Antibodies for RPL9
     ELISAs for RPL9
     CLIAs for RPL9
     Search LifeMap BioReagents cell lines for RPL9
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL9
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RPL9
     SwitchGear Promoter luciferase reporter plasmids for RPL9
     ThermoFisher Antibody for RPL9
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL9
     inGenious Targeting Laboratory - Custom generated mouse model solutions for RPL9
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RPL9
    Customized:
     lentivirus for stable overexpression of RPL9
     lentivirus expression plasmids for stable overexpression of RPL9
     adenovirus for overexpression of RPL9
     LSBio Antibodies in human, mouse, rat for RPL9
    		Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2014 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      RPL9 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4