RPL7L1 Gene
protein-coding GIFtS: 43
GCID: GC06P042847
|
|
ribosomal protein L7-like 1
| |
Aliases
for RPL7L1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ribosomal Protein L7-Like 11 2 | | DJ475N16.41 | | 60S Ribosomal Protein L7-Like 12 |
Export aliases for RPL7L1 gene to outside databasesPrevious GC identifers: GC06P042894 GC06P042956 GC06P042565 |
Summaries
for RPL7L1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RPL7L1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RPL7L1 gene promoter:
POU2F2 (Oct-2.1) Oct-B1 oct-B3 oct-B2 POU2F2 GATA-1 C/EBPalpha CHOP-10 POU2F1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for RPL7L1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL7L1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1RPL7L1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P042847: view genomic region
(about GC identifiers)
Start:
|
42,847,356 bp from pter |
End:
|
42,857,663 bp from pter |
Size:
|
10,308 bases |
Orientation:
|
plus strand |
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Proteins
for RPL7L1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RL7L_HUMAN, Q6DKI1 (See
protein sequence)Recommended Name: 60S ribosomal protein L7-like 1 Size: 246 amino acids; 28661 Da
Secondary accessions: A8K7D4 Q5TFZ5 Q6PEK3Explore the universe of human proteins at neXtProt for RPL7L1: NX_Q6DKI1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6DKI1
RPL7L1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_940888.2
ENSEMBL proteins: ENSP00000418221 ENSP00000346063 ENSP00000445293
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005840 | ribosome |
IEA | -- |
RPL7L1 for ontologies About GeneDecksing
RPL7L1 Antibody Products:
Assay Products for RPL7L1: |
Protein
Domains /
Families
for RPL7L1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPL7L1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6DKI1ProtoNet protein and cluster: Q6DKI1 1 Blocks protein family: IPB000517 Ribosomal protein L30
UniProtKB/Swiss-Prot: RL7L_HUMAN, Q6DKI1Similarity: Belongs to the ribosomal protein L30P family |
Function
for RPL7L1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL7L1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL7L1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RPL7L1 (NM_198486) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPL7L1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL7L1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL7L1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
-- | -- |
RPL7L1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RPL7L1:
|
Pathways & Interactions
for RPL7L1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL7L1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/61 Interacting proteins for RPL7L1 (Q6DKI11, 3 ENSP000003460634) via UniProtKB, MINT, STRING, and/or I2D (see all 61)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006412 | translation |
-- | -- |
RPL7L1 for ontologies About GeneDecksing
|
Drugs & Compounds
for RPL7L1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RPL7L1
Search CenterWatch for drugs/clinical trials and news about RPL7L1 / RL7L
|
Transcripts
for RPL7L1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RPL7L1 gene: NM_198486.2 Unigene Cluster for RPL7L1: Ribosomal protein L7-like 1 Hs.520133 [show with all ESTs]Unigene Representative Sequence: AK07433910 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000483998 ENST00000493763(uc003osq.1) ENST00000397415(uc010jxw.1 uc003osr.1)
ENST00000304734(uc003ost.3 uc003oss.2) ENST00000487619 ENST00000492836
ENST00000497417 ENST00000462348 ENST00000459829 ENST00000424341(uc011dux.1 uc011duy.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL7L1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL7L1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RPL7L1 (NM_198486) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPL7L1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL7L1 |
Additional cDNA sequence: AK021904.1 AK074339.1 AK091341.1 AK098059.1 AK291310.1 AK291949.1 AK297324.1 AK299816.1 BC036861.1 BC058020.1 BC064519.1 BC073890.1 24/38 DOTS entries (see all 38): DT.100031514 DT.100883309 DT.100769559 DT.446102 DT.101973747 DT.100760895 DT.100643471 DT.99965693 DT.100883311 DT.100883312 DT.101985327 DT.92450826 DT.97855350 DT.120680834 DT.92450838 DT.95265993 DT.121315958 DT.121373856 DT.121373768 DT.120796549 DT.120866526 DT.121270621 DT.121373876 DT.100883319 13 AceView cDNA sequences: BC058020 CR601324 BC073890 CR626570 NM_198486 CR595869 BC036861 BI255539 BC064519 AK021904 AK091341 S81578 BM480341
GeneLoc Exon Structure
|
Expression
for RPL7L1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RPL7L1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGGTTAAAG
About this image
See RPL7L1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RPL7L1
SOURCE GeneReport for Unigene cluster: Hs.520133
SABiosciences Custom PCR Arrays for RPL7L1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPL7L1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPL7L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL7L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL7L1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL7L1 |
Orthologs
for RPL7L1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RPL7L1 gene from 7/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RPL7L11 |
ribosomal protein L7-like 1 |
68.29(n)
69.11(a) |
|
422676 NM_001006452.1 NP_001006452.1 |
lizard
(Anolis carolinensis) |
Reptilia |
RPL7L16 |
-- |
65(a) |
1 ↔ 1 |
5(139800754-139804790) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.252482 |
Xenopus laevis transcribed sequence with weak similarity more |
74.37(n) |
|
48062502 |
zebrafish
(Danio rerio) |
Actinopterygii |
rpl7l11 |
ribosomal protein L7-like 1 |
59.49(n)
61.38(a) |
|
322251 NM_199590.1 NP_955884.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
RpL7-like6 |
Ribosomal protein L7-like |
28(a) |
1 ↔ 1 |
2L(12056324-12057416) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G807506 |
60S ribosomal protein L7-1 |
34(a) |
1 ↔ 1 |
1(30348801-30350564) |
rice
(Oryza sativa) |
Liliopsida |
-- |
60S ribosomal protein L7, putative, expressed |
33(a) |
1 ↔ 1 |
8(27125046-27127010) |
ENSEMBL Gene Tree for RPL7L1 (if available)
TreeFam Gene Tree for RPL7L1 (if available) |
Paralogs
for RPL7L1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RPL7L1 gene
- RPL72
2 SIMAP similar genes for RPL7L1 using alignment to 2 protein entries: RL7L_HUMAN (see all proteins):RPL7 WUGSC
RPL7L1 for paralogs About GeneDecksing
5/31 Pseudogenes.org Pseudogenes for RPL7L1 (see all 31)
PGOHUM00000248460 PGOHUM00000248476 PGOHUM00000248675 PGOHUM00000246874 PGOHUM00000248702
|
Genomic Variants
for RPL7L1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RPL7L1 (42847356 - 42857663 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RPL7L1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPL7L1 |
|
Disorders
/ Diseases
for RPL7L1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for RPL7L1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RPL7L1 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with RPL7L1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
|
External Searches for RPL7L1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RPL7L1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RPL7L1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RPL7L1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RPL7L1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RPL7L1 gene:
Search GeneIP for patents involving RPL7L1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RPL7L1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RPL7L1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL7L1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPL7L1 | | | OriGene Protein Over-expression Lysate for RPL7L1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RPL7L1 | | OriGene 3'-UTR Clone for RPL7L1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL7L1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL7L1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RPL7L1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL7L1 |
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