Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RPL7L1 Gene

Aliases for RPL7L1 Gene

  • Ribosomal Protein L7 Like 1 2 3 5
  • Ribosomal Protein L7-Like 1 2 3
  • DJ475N16.4 3

External Ids for RPL7L1 Gene

Previous GeneCards Identifiers for RPL7L1 Gene

  • GC06P042894
  • GC06P042956
  • GC06P042565

Summaries for RPL7L1 Gene

GeneCards Summary for RPL7L1 Gene

RPL7L1 (Ribosomal Protein L7 Like 1) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is RPL7.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL7L1 Gene

Genomics for RPL7L1 Gene

Regulatory Elements for RPL7L1 Gene

Promoters for RPL7L1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RPL7L1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RPL7L1 Gene

Chromosome:
6
Start:
42,879,618 bp from pter
End:
42,889,925 bp from pter
Size:
10,308 bases
Orientation:
Plus strand

Genomic View for RPL7L1 Gene

Genes around RPL7L1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPL7L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPL7L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL7L1 Gene

Proteins for RPL7L1 Gene

  • Protein details for RPL7L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6DKI1-RL7L_HUMAN
    Recommended name:
    60S ribosomal protein L7-like 1
    Protein Accession:
    Q6DKI1
    Secondary Accessions:
    • A8K7D4
    • B7Z652
    • Q5TFZ5
    • Q6PEK3

    Protein attributes for RPL7L1 Gene

    Size:
    246 amino acids
    Molecular mass:
    28661 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RPL7L1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RPL7L1 Gene

Proteomics data for RPL7L1 Gene at MOPED

Post-translational modifications for RPL7L1 Gene

  • Ubiquitination at Lys 122 and Lys 129
  • Modification sites at PhosphoSitePlus

Other Protein References for RPL7L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RPL7L1 Gene

Domains & Families for RPL7L1 Gene

Gene Families for RPL7L1 Gene

Suggested Antigen Peptide Sequences for RPL7L1 Gene

Graphical View of Domain Structure for InterPro Entry

Q6DKI1

UniProtKB/Swiss-Prot:

RL7L_HUMAN :
  • Belongs to the ribosomal protein L30P family.
Family:
  • Belongs to the ribosomal protein L30P family.
genes like me logo Genes that share domains with RPL7L1: view

Function for RPL7L1 Gene

genes like me logo Genes that share phenotypes with RPL7L1: view

Animal Model Products

miRNA for RPL7L1 Gene

miRTarBase miRNAs that target RPL7L1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPL7L1 Gene

Localization for RPL7L1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RPL7L1 Gene COMPARTMENTS Subcellular localization image for RPL7L1 gene
Compartment Confidence
cytosol 4
nucleus 4
mitochondrion 2

Gene Ontology (GO) - Cellular Components for RPL7L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0022625 cytosolic large ribosomal subunit IBA --
genes like me logo Genes that share ontologies with RPL7L1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPL7L1 Gene

Pathways & Interactions for RPL7L1 Gene

SuperPathways for RPL7L1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RPL7L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002181 cytoplasmic translation IBA --
genes like me logo Genes that share ontologies with RPL7L1: view

No data available for Pathways by source and SIGNOR curated interactions for RPL7L1 Gene

Drugs & Compounds for RPL7L1 Gene

No Compound Related Data Available

Transcripts for RPL7L1 Gene

mRNA/cDNA for RPL7L1 Gene

Unigene Clusters for RPL7L1 Gene

Ribosomal protein L7-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RPL7L1 Gene

No ASD Table

Relevant External Links for RPL7L1 Gene

GeneLoc Exon Structure for
RPL7L1
ECgene alternative splicing isoforms for
RPL7L1

Expression for RPL7L1 Gene

mRNA expression in normal human tissues for RPL7L1 Gene

Protein differential expression in normal tissues from HIPED for RPL7L1 Gene

This gene is overexpressed in Lung (47.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RPL7L1 Gene



SOURCE GeneReport for Unigene cluster for RPL7L1 Gene Hs.520133

genes like me logo Genes that share expression patterns with RPL7L1: view

Protein tissue co-expression partners for RPL7L1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPL7L1 Gene

Orthologs for RPL7L1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RPL7L1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RPL7L1 35
  • 87.53 (n)
  • 86.99 (a)
RPL7L1 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RPL7L1 35
  • 88.62 (n)
  • 89.43 (a)
-- 36
  • 89 (a)
OneToMany
-- 36
  • 80 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Rpl7l1 35
  • 84.63 (n)
  • 84.08 (a)
Rpl7l1 16
1700084J12Rik 36
  • 76 (a)
OneToMany
Rpl7l1 36
  • 84 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia RPL7L1 35
  • 99.46 (n)
  • 99.59 (a)
RPL7L1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rpl7l1 35
  • 86.39 (n)
  • 86.12 (a)
oppossum
(Monodelphis domestica)
Mammalia RPL7L1 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RPL7L1 36
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves RPL7L1 35
  • 68.29 (n)
  • 69.11 (a)
RPL7L1 36
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RPL7L1 36
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC76334 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.25248 35
zebrafish
(Danio rerio)
Actinopterygii rpl7l1 35
  • 59.49 (n)
  • 61.38 (a)
rpl7l1 36
  • 61 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta RpL7 36
  • 36 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea rpl-7 36
  • 39 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL7A 36
  • 33 (a)
ManyToMany
RPL7B 36
  • 33 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2360 36
  • 45 (a)
OneToMany
Species with no ortholog for RPL7L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPL7L1 Gene

ENSEMBL:
Gene Tree for RPL7L1 (if available)
TreeFam:
Gene Tree for RPL7L1 (if available)

Paralogs for RPL7L1 Gene

Paralogs for RPL7L1 Gene

(2) SIMAP similar genes for RPL7L1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RPL7L1: view

Variants for RPL7L1 Gene

Sequence variations from dbSNP and Humsavar for RPL7L1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs7952 -- 42,889,468(+) GCCAG(C/T)GTATG utr-variant-3-prime
rs376942 -- 42,878,404(+) gagcc(A/G)agatc upstream-variant-2KB
rs685096 -- 42,878,040(-) ACTAG(C/G/T)GGGGG upstream-variant-2KB
rs1055969 -- 42,888,592(+) CAGAT(A/G)GTGTT utr-variant-3-prime
rs1055972 -- 42,889,179(+) CTCAC(A/G)CCTGT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for RPL7L1 Gene

Variant ID Type Subtype PubMed ID
nsv830651 CNV Loss 17160897

Variation tolerance for RPL7L1 Gene

Residual Variation Intolerance Score: 77.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.07; 37.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RPL7L1 Gene

HapMap Linkage Disequilibrium report
RPL7L1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPL7L1 Gene

Disorders for RPL7L1 Gene

Relevant External Links for RPL7L1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RPL7L1

No disorders were found for RPL7L1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPL7L1 Gene

Publications for RPL7L1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3
  4. Identifying biological pathways that underlie primordial short stature using network analysis. (PMID: 24711643) Hanson D. … Clayton P.E. (J. Mol. Endocrinol. 2014) 3
  5. Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. (PMID: 24823311) Guan W. … Steffen L.M. (Circ Cardiovasc Genet 2014) 3

Products for RPL7L1 Gene

Sources for RPL7L1 Gene

Back to Top

Content