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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL7A Gene

protein-coding   GIFtS: 64
GCID: GC09P136215

Ribosomal Protein L7a

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein L7a1 2     Surfeit 31 2
PLA-X Polypeptide1 2 3     Thyroid Hormone Receptor Uncoupling Protein1 2
Surfeit Locus Protein 31 2 3     L7A2
SURF32 3 5     TRUP2
60S Ribosomal Protein L7a1 2     SURF-33

External Ids:    HGNC: 103641   Entrez Gene: 61302   Ensembl: ENSG000001483037   OMIM: 1856405   UniProtKB: P624243   

Export aliases for RPL7A gene to outside databases

Previous GC identifers: GC09P127304 GC09P127771 GC09P129568 GC09P131491 GC09P133231 GC09P135194 GC09P135217 GC09P135222 GC09P135228 GC09P135235 GC09P135240


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPL7A Gene:
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S
subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct
proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to
the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including
thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA
response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that
do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA
genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with
the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N
terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes
encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
(provided by RefSeq, Jul 2008)

GeneCards Summary for RPL7A Gene: 
RPL7A (ribosomal protein L7a) is a protein-coding gene. Diseases associated with RPL7A include thyroiditis, and adenoiditis, and among its related super-pathways are Eukaryotic Translation Initiation and Metabolism of RNA. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL7A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.2  NT_035014.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL7A gene promoter:
         ER-alpha   HOXA3   HTF   Pax-2   Pax-2a   FOXL1   Pax-2b   Chx10   Sox9   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL7A promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL7A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL7A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34   Ensembl cytogenetic band:  9q34.2   HGNC cytogenetic band: 9q34

RPL7A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL7A gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P136215:  view genomic region     (about GC identifiers)

Start:
136,215,069 bp from pter      End:
136,218,281 bp from pter
Size:
3,213 bases      Orientation:
plus strand

1 alternative location:
Chr9+,NW_003315925 174,308-177,519     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RL7A_HUMAN, P62424 (See protein sequence)
Recommended Name: 60S ribosomal protein L7a  
Size: 266 amino acids; 29996 Da
1 PDB 3D structure from and Proteopedia for RPL7A:
3J3B (3D)    
Secondary accessions: P11518 Q5T8U4

Explore the universe of human proteins at neXtProt for RPL7A: NX_P62424

Explore proteomics data for RPL7A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P62424

  • RPL7A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPL7A Protein Expression
    REFSEQ proteins: NP_000963.1  
    ENSEMBL proteins: 
     ENSP00000361076   ENSP00000416638   ENSP00000361071  
    Reactome Protein details: P62424
    Human Recombinant Protein Products for RPL7A: 
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    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0016020membrane IDA10848616
    GO:0022625cytosolic large ribosomal subunit IDA12962325
    GO:0042788polysomal ribosome IDA10848616

    RPL7A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPL: L ribosomal proteins

    4 InterPro protein domains:
     IPR018492 Ribosomal_L7Ae/L8/Nhp2
     IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45
     IPR004037 Ribosomal_L7Ae_CS
     IPR001921 Ribosomal_L7A/L8

    Graphical View of Domain Structure for InterPro Entry P62424

    ProtoNet protein and cluster: P62424

    1 Blocks protein domain: IPB004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45

    UniProtKB/Swiss-Prot: RL7A_HUMAN, P62424
    Similarity: Belongs to the ribosomal protein L7Ae family


    RPL7A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for RPL7A:
    ribosomal protein L7a (see SURF@)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS8360149
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding IPI15303970
         
    RPL7A for ontologies           About GeneDecksing


    Phenotypes:
         5 GenomeRNAi human phenotypes for RPL7A:
     Decreased cell number, increas  Decreased viability of wild-ty  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 
     S arrest 

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPL7A About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Influenza Infection0.95
    3' -UTR-mediated translational regulation0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92
    3Generic Transcription Pathway
    Gene Expression0.47
    4Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for RPL7A
        Translational Control

    1 GeneGo (Thomson Reuters) Pathway for RPL7A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL7A
        Cytoplasmic Ribosomal Proteins


    5/23        Reactome Pathways for RPL7A (see all 23)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL7A):
        Ribosome


    RPL7A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPL7A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/1026 Interacting proteins for RPL7A (P624241, 2, 3 ENSP000003610764) via UniProtKB, MINT, STRING, and/or I2D (see all 1026)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL8P629172, 3, ENSP000002625844MINT-6542674 MINT-7945693 MINT-6489539 MINT-6488791 I2D: score=3 STRING: ENSP00000262584
    RPL12P300502, 3, ENSP000003547394MINT-6542674 MINT-7945693 MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000354739
    RPS3P233962, 3, ENSP000002785724MINT-6542674 MINT-7945693 MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000278572
    RPL4P365782, 3, ENSP000003114304MINT-7945693 MINT-6489539 MINT-6488791 I2D: score=2 STRING: ENSP00000311430
    RPL11P629132, 3, ENSP000003636764MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000363676
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL7A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPL7A (RL7A)

    Search CenterWatch for drugs/clinical trials and news about RPL7A / RL7A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPL7A gene: 
    NM_000972.2  

    Unigene Cluster for RPL7A:

    Ribosomal protein L7a
    Hs.499839  [show with all ESTs]
    Unigene Representative Sequence: BM908813
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000323345(uc004cde.1) ENST00000496554 ENST00000463740 ENST00000426651
    ENST00000468019 ENST00000485706 ENST00000315731 ENST00000489392 ENST00000492798

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    Additional mRNA sequence: 

    AB056665.1 AK222534.1 AK291123.1 AK311743.1 BC005128.1 BC020989.1 BC021052.1 BC021979.2 
    BC023594.2 BC023624.2 BC032533.1 BC071900.1 BC071901.1 BC073802.1 BC105290.1 M36072.1 
    X06705.1 

    24/141 DOTS entries (see all 141):

    DT.100803645  DT.100708260  DT.121151770  DT.95369981  DT.91887906  DT.121151619  DT.100869883  DT.100653710 
    DT.91888427  DT.120787182  DT.100697013  DT.91888022  DT.100638464  DT.100738310  DT.95217279  DT.95369849 
    DT.95369808  DT.100738342  DT.91888122  DT.91888180  DT.95369985  DT.95322787  DT.100738354  DT.100738360 

    24/3637 AceView cDNA sequences (see all 3637):

    BM542636 BM827513 BQ063058 BQ888571 BQ061088 BQ420715 AA304640 BQ649900 
    BG747587 BQ682194 AW008147 NR_000017 BQ057380 AA313991 BU188868 BQ706058 
    BM551471 BU844571 BQ932751 BU553025 BQ954949 BQ876535 CA422504 BG575953 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RPL7A (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9a · 9b ^ 10a · 10b
    SP1:              -     -     -                 -     -                 -                                                                     
    SP2:                    -     -                 -     -                                                                                       
    SP3:                                                                                      -                                                   
    SP4:                                                                                      -                             -                     
    SP5:                                            -     -                                                                                       


    ECgene alternative splicing isoforms for RPL7A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL7A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTGGACCG
    RPL7A Expression
    About this image


    See RPL7A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL7A

    SOURCE GeneReport for Unigene cluster: Hs.499839
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL7A gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl7a1 , 5 ribosomal protein L7A1, 5 88.35(n)1
    99.62(a)1
      2 (19.10 cM)5
    271761  NM_013721.31  NP_038749.11 
     269107645 
    chicken
    (Gallus gallus)
    Aves RPL7A1 ribosomal protein L7a 82.83(n)
    96.62(a)
      417158  NM_001004379.1  NP_001004379.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL7A6
    Uncharacterized protein
    98(a)
    1 ↔ 1
    AAWZ02038880(2185-2310)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480545762   -- 80.3(n)    48054576 
    zebrafish
    (Danio rerio)
    Actinopterygii BC059533.12   -- 82.27(n)   337010  BC059533.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL7A1 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein L7A1
    68(a)3
    65.39(n)1
    68.32(a)1
      1 6B13
    315881  NM_078508.51  NP_511063.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y24D9A.4a3
    rpl-7A1
    Protein RPL-7A1 63(a)
    (best of 2)3
    61.61(n)1
    62.26(a)1
      IV(4389374-4390762)3
    1772031  NM_171316.51  NP_741371.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL8B(YLL045C)4
    RPL8B1
    Ribosomal protein L4 of the large (60S) ribosomal subunit, more4
    Rpl8bp1
    58.5(n)1
    58.63(a)1
      12(48629-47859)4
    8506821, 4  NP_013055.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G476101 60S ribosomal protein L7a-1 58.6(n)
    57.94(a)
      819374  NM_130329.3  NP_182283.1 
    rice
    (Oryza sativa)
    Liliopsida Os.378822 Oryza sativa (japonica cultivar-group) cDNA clone0 more 72.59(n)    AK061725.1 


    ENSEMBL Gene Tree for RPL7A (if available)
    TreeFam Gene Tree for RPL7A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL7A gene
    1 SIMAP similar gene for RPL7A using alignment to 3 protein entries:     RL7A_HUMAN (see all proteins):
    RP-L7a

    RPL7A for paralogs           About GeneDecksing


    5/92 Pseudogenes.org Pseudogenes for RPL7A (see all 92)
    PGOHUM00000238400 PGOHUM00000238502 PGOHUM00000238570 PGOHUM00000238820 PGOHUM00000238894


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    4 SNPs in RPL7A are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0147214
    ----see VAR_0147212 A V mis40--------
    rs2012666671,2
    --136228141(+) GGAGG-/CCCACC 1 -- us2k10--------
    rs6044021,2
    C,A--136228144(+) AGGCCC/ACCCCC 1 -- us2k15Minor allele frequency- A:0.00NA WA CSA 9
    rs1856981401,2
    C--136228149(+) ACCCCA/CCACTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL7A (136215069 - 136218281 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RPL7A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2739138CNV Deletion23290073
    nsv894076CNV Loss21882294
    dgv8325n71CNV Loss21882294
    nsv894079CNV Loss21882294
    nsv894080CNV Loss21882294
    nsv894057CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 185640    OMIM disorders: --

    UniProtKB/Swiss-Prot: RL7A_HUMAN, P62424
  • Note=Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene

  • 8 diseases for RPL7A:    About MalaCards
    thyroiditis    adenoiditis    adenoid cystic carcinoma    tuberous sclerosis
    influenza    prostate cancer    prostatitis    breast cancer


    RPL7A for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPL7A
    Human Genome Epidemiology (HuGE) Navigator: RPL7A (3 documents)

    Export disorders for RPL7A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL7A gene, integrated from 9 sources (see all 88):
    (articles sorted by number of sources associating them with RPL7A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Activation of the receptor kinase domain of the trk oncogene by recombination with two different cellular sequences. (PubMed id 2966065)1, 2, 3 Kozma S.C.... Hynes N.E. (1988)
    2. Human L7a ribosomal protein: sequence, structural organization, and expression of a functional gene. (PubMed id 8482538)1, 2, 9 De Falco S.... Pietropaolo C. (1993)
    3. The organization and expression of the human L7a ribosomal protein gene. (PubMed id 1756182)1, 2, 9 Colombo P.... Fried M. (1991)
    4. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a. (PubMed id 2403926)1, 3 Ziemiecki A....Kozma S. (1990)
    7. A human cellular sequence implicated in trk oncogene activation is DNA damage inducible. (PubMed id 1696715)1, 2 Ben-Ishai R.... Kapten I. (1990)
    8. Modulation of expression of ribosomal protein L7a (rpL7a) by ethanol in human breast cancer cells. (PubMed id 11759826)1, 9 Zhu Y....Luo J. (2001)
    9. Down-regulation of ribosomal protein L7A in human ost eosarcoma. (PubMed id 19125294)1, 9 Zheng S.E....Tang L.N. (2009)
    10. Evolution of U24 and U36 snoRNAs encoded within introns of vertebrate rpL7a gene homologs: unique features of mammalian U36 variants. (PubMed id 9703018)1, 9 Gilley J. and Fried M. (1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6130 HGNC: 10364 AceView: DBHandRPL7AandSURF2 Ensembl:ENSG00000148303 euGenes: HUgn6130
    ECgene: RPL7A Kegg: 6130 H-InvDB: RPL7A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL7A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPL7A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPL7A gene:
    Search GeneIP for patents involving RPL7A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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