Subcategory (RNA class) for RPL41 Gene
Aliases for RPL41 Gene
External Ids for RPL41 Gene
Previous GeneCards Identifiers for RPL41 Gene
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located in the cytoplasm. The protein can interact with the beta subunit of protein kinase CKII and can stimulate the phosphorylation of DNA topoisomerase II-alpha by CKII. Two alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPL41 Gene
RPL41 (Ribosomal Protein L41) is a Protein Coding gene, and is affiliated with the lncRNA class. Diseases associated with RPL41 include Subvalvular Aortic Stenosis. Among its related pathways are Viral mRNA Translation and Transport to the Golgi and subsequent modification. GO annotations related to this gene include RNA binding and structural constituent of ribosome. An important paralog of this gene is ENSG00000279483.
UniProtKB/Swiss-Prot for RPL41 Gene
Interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase II alpha by CKII.