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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL4 Gene

protein-coding   GIFtS: 59
GCID: GC15M066790

ribosomal protein L4

 Explore 11 diseases affiliated with
RPL4 via our new
 Human Malady Compendium 
Biological research products
for RPL4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ribosomal Protein L41 2
L41 2
60S Ribosomal Protein L12 3
60S Ribosomal Protein L42
RPL13

External Ids:    HGNC: 103531   Entrez Gene: 61242   Ensembl: ENSG000001744447   OMIM: 1804795   UniProtKB: P365783   

Export aliases for RPL4 gene to outside databases

Previous GC identifers: GC15M062584 GC15M059890 GC15M064370 GC15M064507 GC15M064578 GC15M043627


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPL4:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L4E family of ribosomal
proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPL4 (Ribosomal protein L4)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL4 gene promoter:
         TBP   FOXF2   TFIID   Meis-1a   Meis-1   Meis-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL4 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22   Ensembl cytogenetic band:  15q22.31   HGNC cytogenetic band: 15q22

RPL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL4 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M066790:  view genomic region     (about GC identifiers)

Start:
66,790,355 bp from pter      End:
66,816,870 bp from pter
Size:
26,516 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RL4_HUMAN, P36578 (See protein sequence)
Recommended Name: 60S ribosomal protein L4  
Size: 427 amino acids; 47697 Da
Subunit: May bind IPO9 with low affinity. Interacts with RBM3 (By similarity)
Secondary accessions: A8K502 P39029 Q4VBR0 Q969Z9

Explore the universe of human proteins at neXtProt for RPL4: NX_P36578

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P36578

  • RPL4 Protein expression data from MOPED and PaxDb:    About this image 
    RPL4 Protein Expression
    REFSEQ proteins: NP_000959.2  
    ENSEMBL proteins: 
     ENSP00000311430   ENSP00000454281   ENSP00000457442   ENSP00000457268  
    Reactome Protein details: P36578
    Human Recombinant Protein Products for RPL4: 
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    Uscn Proteins for RPL4

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----

    RPL4 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RPL4


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RPL4 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR025755 Ribos_L4_C_dom
     IPR023574 Ribosomal_L4_dom
     IPR002136 Ribosomal_L4/L1e
     IPR013000 Ribosomal_L4/L1e_euk/arc_CS

    Graphical View of Domain Structure for InterPro Entry P36578

    ProtoNet protein and cluster: P36578

    1 Blocks protein family: IPB002136 Ribosomal protein L4/L1e

    UniProtKB/Swiss-Prot: RL4_HUMAN, P36578
    Similarity: Belongs to the ribosomal protein L4P family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for RPL4:
    60S ribosomal protein L4

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS8268230
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding ----
         
    RPL4 for ontologies           About GeneDecksing


    Phenotypes:
         6 GenomeRNAi human phenotypes for RPL4:
     Decreased cell number, increas  Increased Salmonella enterica   Nuclear 60S biogenesis defects  Nuclear pre-40S maturation def 
     S arrest  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RPL4 

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate RPL4:
    hsa-miR-4272
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    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    Viral Protein Synthesis1.00
    Cytoplasmic Ribosomal Proteins0.86
    Viral mRNA Translation1.00
    CFTR translational fidelity (class I mutations)0.83
    Influenza Viral RNA Transcription and Replication1.00
    SMG6 Cleaves mRNA with Premature Termination Codon0.80
    Synthesis of nascent polypeptide containing signal sequence1.00
    L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Metabolism of mRNA
    Metabolism of mRNA1.00
    Metabolism of RNA0.92
    3Disease
    Disease1.00
    4TNF-alpha/NF-kB Signaling Pathway
    TNF-alpha/NF-kB Signaling Pathway1.00
    5Generic Transcription Pathway
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL4
        CFTR translational fidelity (class I mutations)

    2 BioSystems Pathways for RPL4 
        Cytoplasmic Ribosomal Proteins
    TNF-alpha/NF-kB Signaling Pathway

    5/28        Reactome Pathways for RPL4 (see all 28)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL4):
        Ribosome


    RPL4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/1116 Interacting proteins for RPL4 (P365781, 2, 3 ENSP000003114304) via UniProtKB, MINT, STRING, and/or I2D (see all 1116)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RPL4 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPL4
    2 Novoseek chemical compound relationships for RPL4 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    erythromycin 64.4 6 15561835 (2), 19197244 (1), 2256953 (1)
    azithromycin 56.7 1 17110371 (1)

    Search CenterWatch for drugs/clinical trials and news about RPL4 / RL4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPL4 gene: 
    NM_000968.3  

    Unigene Clusters for RPL4:

    Ribosomal protein L4
    Hs.186350  [show with all ESTs], Hs.644628  [show with all ESTs]
    Unigene Representative Sequences: AK125772, BC002450
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000307961(uc002apv.3) ENST00000567229 ENST00000565723 ENST00000568588(uc002apx.3)
    ENST00000561775 ENST00000569696 ENST00000564744 ENST00000564647 ENST00000563473
    ENST00000566039(uc010ujq.2) ENST00000564439 ENST00000566622 ENST00000569438
    ENST00000566624 ENST00000561554 ENST00000566491 ENST00000564517

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    hsa-miR-4272
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    Additional cDNA sequence: 

    AB208977.1 AK130784.1 AK223057.1 AK291117.1 AK291859.1 BC001365.2 BC002450.1 BC005817.2 
    BC007748.2 BC007996.1 BC009888.2 BC010151.2 BC014653.1 BC018840.2 BC040610.1 BC066925.1 
    BC095427.1 D23660.1 L20868.2 

    24/147 DOTS entries (see all 147):

    DT.100743615  DT.100743679  DT.80101635  DT.92324759  DT.65286226  DT.95377953  DT.95378147  DT.91912327 
    DT.92472330  DT.100743721  DT.100743576  DT.100743611  DT.100853932  DT.100743603  DT.100054121  DT.92472452 
    DT.87001093  DT.97846736  DT.121047748  DT.100743696  DT.91643443  DT.92472320  DT.92472397  DT.100743629 

    24/108 AceView cDNA sequences (see all 108):

    BC066925 CR607454 CR596506 CR599223 CR623277 CR624000 CR608966 BC030000 
    CR618330 BC010151 CR623016 CR615745 CR596594 CR626518 CR592711 CR605656 
    BC007748 CR590785 CR597698 CR625092 CR598274 CR619311 CR612355 BC009888 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RPL4 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b
    SP1:              -           -     -     -                       -                                                                                       
    SP2:                                                                                                  -                                                   
    SP3:              -                 -     -     -                                                                                                         
    SP4:              -                                               -                                                                                       
    SP5:                                -     -     -                                                                                                         


    ECgene alternative splicing isoforms for RPL4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGCCGGAACA
    RPL4 Expression
    About this image
    See RPL4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL4

    SOURCE GeneReport for Unigene clusters: Hs.186350 Hs.644628
        SABiosciences Custom PCR Arrays for RPL4

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL4 gene from 9/36 species (see all 36)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl41 , 5 ribosomal protein L41, 5 87.98(n)1
    94.71(a)1
      9 (34.54 cM)5
    678911  NM_024212.41  NP_077174.11 
     641733875 
    chicken
    (Gallus gallus)
    Aves RPL41 ribosomal protein L4 75.86(n)
    83.21(a)
      415551  NM_001007479.1  NP_001007480.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL46
    --
    95(a)
    1 ↔ 1
    GL343467.1(141674-145172)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC643182 ribosomal protein 79.7(n)    BC041744.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa97a022 Danio rerio cDNA clone MGC56659 IMAGE5916329, complete more 79.13(n)    BC049520.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL13
    RpL41
    protein biosynthesis structural constituent
    of more3
    Ribosomal protein L41
    62(a)3
    60.84(n)1
    66.07(a)1
      98B63
    433491  NM_079814.21  NP_524538.21 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-41 , 3 ribosomal protein L13
    Protein RPL-41
    58(a)3
    57.49(n)1
    58.68(a)1
      I(4645738-4646958)3
    1720741  NM_059015.31  NP_491416.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G096301 60S ribosomal protein L4-1 55.76(n)
    57.91(a)
      820120  NM_111797.2  NP_187574.1 
    rice
    (Oryza sativa)
    Liliopsida Os.87672 Oryza sativa (japonica cultivar-group) putative 60S more 71.02(n)    NM_185075.1 


    ENSEMBL Gene Tree for RPL4 (if available)
    TreeFam Gene Tree for RPL4 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL4 gene

    RPL4 for paralogs           About GeneDecksing


    5/10 Pseudogenes.org Pseudogenes for RPL4 (see all 10)
    PGOHUM00000248054 PGOHUM00000244334 PGOHUM00000245066 PGOHUM00000263073 PGOHUM00000246349


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/223 NCBI SNPs in RPL4 are shown (see all 223    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1826451071,2
    --66791158(+) ACTCAC/TTGGCT 3 -- ds5001 us2k10--------
    rs734717651,2
    C--66791174(+) GCTCTG/CCCCAC 3 -- us2k1 ds50014Minor allele frequency- C:0.25WA CSA NS 262
    rs1485467111,2
    --66791197(+) AAGTGC/TTGGGA 3 -- ds5001 us2k10--------
    rs1454248171,2
    --66791252(+) ATGGGC/TGAAAA 3 -- us2k1 ds50010--------
    rs44322201,2
    C,F,H--66791258(+) GAAAAT/CACTCA 3 -- ds5001 us2k120Minor allele frequency- C:0.28NS EA NA WA CSA 2151
    rs797204751,2
    C,F--66791265(+) CTCAAC/TTCTAT 3 -- ds5001 us2k13Minor allele frequency- T:0.07WA EA NS 378
    rs1478324961,2
    --66791276(+) TGTTAG/TAGCTG 3 -- ds5001 us2k10--------
    rs620118801,2
    C,F--66791348(+) CTCCAG/ATTGTG 3 -- us2k1 ds50014Minor allele frequency- A:0.08NA NS 264
    rs1887879421,2
    --66791502(+) TTTTTA/TAAATC 2 -- ds5001 us2k10--------
    rs754578501,2
    C,F--66791563(+) TTATAC/ACACAC 2 -- us2k1 ds50012Minor allele frequency- A:0.16WA NS 258

    HapMap Linkage Disequilibrium report for RPL4 (66790355 - 66816870 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RPL4: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPL4
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RPL4 for disorders           About GeneDecksing

    OMIM gene information: 180479    OMIM disorders: --

    11 diseases for RPL4:    About MalaCards
    cat-scratch disease    treacher collins syndrome    metastasis efficiency    intrahepatic cholangiocarcinoma
    cholangiocarcinoma    pneumonia    colon cancer    ovarian cancer
    prostate cancer    prostatitis    malaria

    1 disease from the University of Copenhagen DISEASES database for RPL4:
    cat-scratch disease

    1 Novoseek disease relationship for RPL4 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cancer 0 1 9724090 (1)


    Export disorders for RPL4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL4 gene, integrated from 9 sources (see all 90):
    (articles sorted by number of sources associating them with RPL4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein. (PubMed id 8268230)1, 2, 3, 9 Bagni C.... Amaldi F. (1993)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. (PubMed id 11823430)1, 2 Jaekel S.... Goerlich D. (2002)
    4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    5. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (1998)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
    8. Large ribosomal protein 4 increases efficiency of vira l recoding sequences. (PubMed id 22718819)1 Green L....Goff S.P. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6124 HGNC: 10353 AceView: RPL4 Ensembl:ENSG00000174444 euGenes: HUgn6124
    ECgene: RPL4 Kegg: 6124 H-InvDB: RPL4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPL4 gene:
    Search GeneIP for patents involving RPL4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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