Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RPL39 Gene

protein-coding   GIFtS: 55
GCID: GC0XM118920

Ribosomal Protein L39

(Previous name: ribosomal protein L39 pseudogene 42)
(Previous symbol: RPL39P42)
  See RPL39-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ribosomal Protein L391 2
RPL39P421 2
Ribosomal Protein L39 Pseudogene 421
60S Ribosomal Protein L392
L392
RPL39_23_18062

External Ids:    HGNC: 103501   Entrez Gene: 61702   Ensembl: ENSG000001989187   OMIM: 3008995   UniProtKB: P628913   
ORGUL members:         

Export aliases for RPL39 gene to outside databases

Previous GC identifers: GC0XM113738 GC0XM115906 GC0XM116895 GC0XM117674 GC0XM118702 GC0XM118804 GC0XM108414


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for RPL39 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the S39E family
of ribosomal proteins. It is located in the cytoplasm. In rat, the protein is the smallest, and one of the most
basic, proteins of the ribosome. This gene is co-transcribed with the U69 small nucleolar RNA gene, which is
located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL39 Gene:
RPL39 (ribosomal protein L39) is a protein-coding gene. Diseases associated with RPL39 include pure red-cell aplasia. GO annotations related to this gene include structural constituent of ribosome and RNA binding. An important paralog of this gene is RPL39L.

Gene Wiki entry for RPL39 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_011786.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL39 gene promoter:
         RP58   NCX/Ncx   CUTL1   GATA-1   GATA-2   Ik-2   FOXJ2 (long isoform)   FOXJ2   Ik-1   En-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RPL39

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL39


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq24   Ensembl cytogenetic band:  Xq24   HGNC cytogenetic band: Xq24

RPL39 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL39 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM118920:  view genomic region     (about GC identifiers)

Start:
118,920,467 bp from pter      End:
118,925,606 bp from pter
Size:
5,140 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RL39_HUMAN, P62891 (See protein sequence)
Recommended Name: 60S ribosomal protein L39  
Size: 51 amino acids; 6407 Da
Miscellaneous: This protein is the smallest and one of the most basic of the proteins in liver ribosomes (By
similarity)
1 PDB 3D structure from and Proteopedia for RPL39:
3J3B (3D)    
Secondary accessions: P02404 P39025 Q9BYF2

Explore the universe of human proteins at neXtProt for RPL39: NX_P62891

Post-translational modifications: 

  • Ubiquitination2 at Lys18
  • Modification sites at PhosphoSitePlus
  • REFSEQ proteins: NP_000991.1  
    ENSEMBL proteins: 
     ENSP00000355315  
    Reactome Protein details: P62891

    RPL39 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for RPL39
    GenScript Custom Purified and Recombinant Proteins Services for RPL39
    Novus Biologicals RPL39 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPL39

     
    Search eBioscience for Proteins for RPL39 

    RPL39 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for RPL39
    OriGene Custom Antibody Services for RPL39
    Novus Biologicals RPL39 Antibodies
    Abcam antibodies for RPL39
    Cloud-Clone Corp. Antibodies for RPL39
    Search ThermoFisher Antibodies for RPL39
    LSBio Antibodies in human, mouse, rat for RPL39

    RPL39 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RPL39
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPL39
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RPL39
    Cloud-Clone Corp. CLIAs for RPL39
    Search eBioscience for ELISAs for RPL39 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RPL: L ribosomal proteins

    3 InterPro protein domains:
     IPR020083 Ribosomal_L39_CS
     IPR000077 Ribosomal_L39
     IPR023626 Ribosomal_L39e_dom

    Graphical View of Domain Structure for InterPro Entry P62891

    ProtoNet protein and cluster: P62891

    UniProtKB/Swiss-Prot: RL39_HUMAN, P62891
    Similarity: Belongs to the ribosomal protein L39e family


    Find genes that share domains with RPL39           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS8764829
    GO:0003735structural constituent of ribosome TAS8764829
         
    Find genes that share ontologies with RPL39           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPL39:
     Nuclear 60S biogenesis defects  Nucleoplasmic pre-40S maturati 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL39
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL39

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL39
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL39

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL39:
    hsa-mir-92a-3p (MIRT048919), hsa-mir-26b-5p (MIRT029161), hsa-mir-155-5p (MIRT020677), hsa-mir-30c-5p (MIRT047878)

    Block miRNA regulation of human, mouse, rat RPL39 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate RPL39:
    hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidRPL39 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RPL39
    Predesigned siRNA for gene silencing in human, mouse, rat RPL39

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RPL39

    Clone
    Products:
         
    OriGene clones in human, mouse for RPL39 (see all 7)
    OriGene ORF clones in mouse, rat for RPL39
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL39 (NM_001000)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL39
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL39

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RPL39
    Browse ESI BIO Cell Lines and PureStem Progenitors for RPL39 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL39


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit TAS8764829

    Find genes that share ontologies with RPL39           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for RPL39 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease


    Find genes that share SuperPaths with RPL39           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL39
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL39
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL39 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL39):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL39
    Interactions:

        Search GeneGlobe Interaction Network for RPL39

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL39 (ENSP000003553154) via UniProtKB, MINT, STRING, and/or I2D (see all 137)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL5ENSP000003593454STRING: ENSP00000359345
    RPL18ENSP000000847954STRING: ENSP00000084795
    RPL30ENSP000002870384STRING: ENSP00000287038
    RPL35ENSP000002594694STRING: ENSP00000259469
    RPL11ENSP000003636764STRING: ENSP00000363676
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS8764829
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPL39           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL39 (RL39)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RPL39 gene: 
    NM_001000.3  

    Unigene Clusters for RPL39:

    Ribosomal protein L39
    Hs.300141  [show with all ESTs], Hs.558387  [show with all ESTs]
    Unigene Representative Sequences: CD556052, BU566074
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000477403 ENST00000468844 ENST00000361575(uc004erx.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RPL39 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate RPL39:
    hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidRPL39 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RPL39
    Predesigned siRNA for gene silencing in human, mouse, rat RPL39
    Clone
    Products:
         
    OriGene clones in human, mouse for RPL39 (see all 7)
    OriGene ORF clones in mouse, rat for RPL39
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL39 (NM_001000)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL39
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL39
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RPL39
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL39
      QuantiTect SYBR Green Assays in human, mouse, rat RPL39
      QuantiFast Probe-based Assays in human, mouse, rat RPL39

    Additional mRNA sequence: BC070205.1 

    Selected DOTS entries (see all 35):

    DT.95137965  DT.100741480  DT.92038448  DT.95120025  DT.100859048  DT.97800524  DT.91914786  DT.100741485 
    DT.100741503  DT.120990764  DT.121304871  DT.91942842  DT.95331017  DT.98131909  DT.100638469  DT.100741512 
    DT.121355960  DT.91769537  DT.100741475  DT.100741499  DT.100741505  DT.102822622  DT.121304859  DT.121304893 

    Selected AceView cDNA sequences (see all 1120):

    AA447199 AI718103 AI859041 AA316583 AA152128 BM772817 N29613 BE392491 
    AA977977 D58434 AW263598 BM750270 BM693170 F25884 AI081670 BU543568 
    BE675359 AI805128 F31216 AA308818 CB138867 BM705322 BM741688 BM836269 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RPL39 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTACCATATC
    RPL39 Expression
    About this image


    RPL39 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
     
     Prostate (Endocrine System)
    RPL39 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene clusters: Hs.300141 Hs.558387
        Custom PCR Arrays for RPL39
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RPL39
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL39
    QuantiTect SYBR Green Assays in human, mouse, rat RPL39
    QuantiFast Probe-based Assays in human, mouse, rat RPL39
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL39

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL39 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl391 , 5 ribosomal protein L391, 5 89.54(n)1
    100(a)1
      X (21.50 cM)5
    672481  NM_026055.11  NP_080331.11 
     370825205 
    chicken
    (Gallus gallus)
    Aves RPL391 ribosomal protein L39 83.66(n)
    98.04(a)
      374132  NM_204272.1  NP_989603.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    96(a)
    1 → many
    GL343950.1(105208-107407)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480473812   -- 79.88(n)    48047381 
    zebrafish
    (Danio rerio)
    Actinopterygii CK400694.12   -- 78.47(n)    CK400694.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL396
    Ribosomal protein L39
    73(a)
    1 → many
    2R(19949376-19949952)
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-396
    Protein RPL-39 (rpl-39) mRNA, complete cds
    75(a)
    1 → many
    V(7775738-7776086) WBGene00004453
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL396
    Protein component of the large (60S) ribosomal sub...
    63(a)
    1 → many
    X(75933-76474) YJL189W
    barley
    (Hordeum vulgare)
    Liliopsida Hv.82902 Transcribed sequence with moderate similarity to protein more 71.98(n)    AV925150.1 


    ENSEMBL Gene Tree for RPL39 (if available)
    TreeFam Gene Tree for RPL39 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RPL39 gene
    RPL39L2  
    2 SIMAP similar genes for RPL39 using alignment to 1 protein entry:     RL39_HUMAN:
    RPL39P5    RPL39L

    Find genes that share paralogs with RPL39           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPL39 (see all 44)
    PGOHUM00000238541 PGOHUM00000261108 PGOHUM00000239510 PGOHUM00000248489 PGOHUM00000247747


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for RPL39 (see all 145)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1867028861,2
    C--108413582(+) GGTCCA/GGACCA 1 -- int10--------
    rs78897621,2
    C,F,A--108413637(+) TTCTGC/GGATTG 1 -- int12Minor allele frequency- G:0.34WA NS 112
    rs1906942101,2
    --108413661(+) CTAGAC/TGTGAA 1 -- int10--------
    rs558502321,2
    C,F--118913493(+) CGTGGT/CGGCTC 1 -- int11Minor allele frequency- C:0.34NS 116
    rs1810642101,2
    C--118913518(+) AACACC/TTTGGG 1 -- int10--------
    rs1864002761,2
    --118913580(+) AACATG/TGTGAA 1 -- int10--------
    rs1420877351,2
    C--118913879(+) TACTGG/TATAGT 1 -- int10--------
    rs1117367421,2
    C--118913958(+) AAAGAA/TAGGCC 1 -- ut310--------
    rs1908597971,2
    --118913996(+) ACCAAC/TGTGTT 1 -- ut310--------
    rs1121732031,2
    C,F--118914029(+) ACACGT/CCGAAA 1 -- ut312Minor allele frequency- C:0.02CSA NS 132

    HapMap Linkage Disequilibrium report for RPL39 (118920467 - 118925606 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RPL39: --
    Locus Specific Mutation Databases (LSDB): RPL39

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL39
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL39

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 300899    OMIM disorders: --

    1 disease for RPL39:    
    About MalaCards
    pure red-cell aplasia

    2 diseases from the University of Copenhagen DISEASES database for RPL39:
    Diamond-Blackfan anemia     Pure red-cell aplasia

    Find genes that share disorders with RPL39           About GenesLikeMe


    Export disorders for RPL39 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RPL39 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with RPL39)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a cDNA encoding human ribosomal protein L39. (PubMed id 8764829)1, 2, 3, 9 Otsuka S.... Itakura M. (Biochim. Biophys. Acta 1996)
    2. Primary structures and sequence analysis of human ribosomal proteins L39 and S27. (PubMed id 8908372)1, 2, 9 Tsui S.K.W.... Lee C.Y. (Biochem. Mol. Biol. Int. 1996)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (Genome Res. 2002)
    5. A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders. (PubMed id 11401437)1, 2 Uechi T.... Kenmochi N. (Genomics 2001)
    6. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    7. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes. (PubMed id 19123937)1 Balasubramanian S....Gerstein M. (Genome Biol. 2009)
    10. The molecular mechanics of eukaryotic translation. (PubMed id 15189156)1 Kapp L.D. and Lorsch J.R. (Annu. Rev. Biochem. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 6170 HGNC: 10350 AceView: RPL39 Ensembl:ENSG00000198918 euGenes: HUgn6170
    ECgene: RPL39 Kegg: 6170 H-InvDB: RPL39

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RPL39 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RPL39 gene:
    Search GeneIP for patents involving RPL39

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for RPL39   OriGene RNAi products in human, mouse, rat for RPL39  
     OriGene qPCR primer pairs and template standards for RPL39   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RPL39  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RPL39   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPL39   OriGene Custom Protein Services for RPL39  

     
     
     Block miRNA regulation of human, mouse, rat RPL39 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RPL39
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL39 Predesigned siRNA for gene silencing in human, mouse, rat RPL39
     QuantiFast Probe-based Assays in human, mouse, rat RPL39 QuantiTect SYBR Green Assays in human, mouse, rat RPL39
     Custom PCR Arrays for RPL39 Search Chromatin IP Primers for RPL39
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL39  Search GeneGlobe Interaction Network for RPL39
     Regulatory tfbs in RPL39 promoter
     GenScript Custom Purified and Recombinant Proteins Services for RPL39 GenScript cDNA clones with any tag delivered in your preferred vector for RPL39
     GenScript Custom Assay Services for RPL39 GenScript Custom overexpressing Cell Line Services for RPL39
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RPL39 (RL39)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RPL39 antibodies
     RPL39 proteins
     Antibodies for RPL39
     See all of Abcam's Antibodies, Kits and Proteins for RPL39
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RPL39
     Antibodies for RPL39
     ELISAs for RPL39
     CLIAs for RPL39



     Browse ESI BIO Cell Lines and PureStem Progenitors for RPL39
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL39
     SwitchGear 3'UTR luciferase reporter plasmids for RPL39
     Browse SwitchGear Promoter luciferase reporter plasmids for RPL39
     Search ThermoFisher Antibodies for RPL39
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL39
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL39
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL39
     LSBio Antibodies in human, mouse, rat for RPL39
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for RPL39
      Search eBioscience for proteins for RPL39
      Search eBioscience for elisas for RPL39
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RPL39 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4