Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL38 Gene

protein-coding   GIFtS: 57
GCID: GC17P072202

ribosomal protein L38
 Explore 8 diseases affiliated with
RPL38 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPL38    

Aliases
for RPL38 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein L381 2
L381 2
60S Ribosomal Protein L382

External Ids:    HGNC: 103491   Entrez Gene: 61692   Ensembl: ENSG000001728097   OMIM: 6041825   UniProtKB: P631733   

Export aliases for RPL38 gene to outside databases

Previous GC identifers: GC17P072221 GC17P075257 GC17P072663 GC17P072796 GC17P069711 GC17P067610


Summaries
for RPL38 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPL38:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of
ribosomal proteins. It is located in the cytoplasm. Alternative splice variants have been identified, both encoding
the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of
this gene dispersed through the genome, including one located in the promoter region of the type 1 angiotensin II
receptor gene. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPL38 (60S ribosomal protein L38)


Genomic Views
for RPL38 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL38 gene promoter:
         Max1   Elk-1   Pbx1a   Evi-1   GATA-2   POU2F1   POU2F1a   FOXJ2 (long isoform)   FOXJ2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPL38 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL38

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL38


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.1

RPL38 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL38 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P072202:  view genomic region     (about GC identifiers)

Start:
 72,199,721 bp from pter      End:
 72,206,794 bp from pter
Size:
 7,074 bases      Orientation:
 plus strand

Proteins
for RPL38 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RL38_HUMAN, P63173 (See protein sequence)
Recommended Name: 60S ribosomal protein L38  
Size: 70 amino acids; 8218 Da
Secondary accessions: B2R5A8 P23411

Explore the universe of human proteins at neXtProt for RPL38: NX_P63173

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P63173

    • RPL38 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_000990.1  NP_001030335.1  

    ENSEMBL proteins: 
     ENSP00000390279   ENSP00000309830   ENSP00000463312   ENSP00000462837   ENSP00000462580  
     ENSP00000434243  
    Reactome Protein details: P63173
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: RPL38
    OriGene Protein Over-expression Lysate (see all 2): RPL38
    OriGene Custom Protein Services for RPL38 
    GenScript Custom Purified and Recombinant Proteins Services for RPL38
    Novus Biologicals RPL38 Proteins
    Novus Biologicals RPL38 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPL38

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0022625cytosolic large ribosomal subunit IDA12962325


    RPL38 for ontologies           About GeneDecksing



    RPL38 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RPL38 
    GenScript Custom Superior Antibodies Services for RPL38
    Search for Antibodies for RPL38 at Abcam  
    Uscn Antibodies for RPL38
    Search ThermoFisher Antibodies for RPL38

    Assay Products for RPL38: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPL38
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for RPL38

    Protein Domains /
    Families
    for RPL38 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPL38 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR002675 Ribosomal_L38e

    Graphical View of Domain Structure for InterPro Entry P63173

    ProtoNet protein and cluster: P63173

    UniProtKB/Swiss-Prot: RL38_HUMAN, P63173
    Similarity: Belongs to the ribosomal protein L38e family


    Function
    for RPL38 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for RPL38:
    60S ribosomal protein L38

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): RPL38
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL38
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RPL38
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL38 (see all 7)
    OriGene shRNA RFP: RPL38
    OriGene siRNA: RPL38
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL38

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RPL38

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL38 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL38 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): RPL38 (NM_000999)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL38
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL38 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for RPL38
    Search LifeMap BioReagents cell lines for RPL38

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPL38

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS9375793
    GO:0003735structural constituent of ribosome NAS12962325


    RPL38 for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for RPL38:
     Decreased cell number, increas  Decreased viability of wild-ty  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 
     S arrest 

    Animal Models:
         Mouse knock-out Rpl38tm1Rugg for RPL38
         15/19 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Rpl38) (see all 19):
     cardiovascular system  cellular  craniofacial  digestive/alimentary  embryogenesis 
     growth/size  hearing/vestibular/ear  hematopoietic system  homeostasis/metabolism  immune system 
     integument  limbs/digits/tail  mortality/aging  nervous system  pigmentation 

    RPL38 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for RPL38 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    3Disease
    		Disease1.00
    4Generic Transcription Pathway
    		Gene Expression0.46
    5Asparagine N-linked glycosylation
    		Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL38
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL38 
        Cytoplasmic Ribosomal Proteins

    5/28        Reactome Pathways for RPL38 (see all 28)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL38):
        Ribosome


    RPL38 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL38

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/374 Interacting proteins for RPL38 (P631731, 2, 3 ENSP000003098304) via UniProtKB, MINT, STRING, and/or I2D (see all 374)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RUVBL2Q9Y2302, 3, ENSP000002214134MINT-6489217 MINT-6488488 I2D: score=1 STRING: ENSP00000221413
    NME1-NME2P223921, 3EBI-359141,EBI-713693 I2D: score=2 
    NME2P223921, 3EBI-359141,EBI-713693 I2D: score=2 
    TFE3P195321, 3, ENSP000003141294EBI-359141,EBI-1048957 I2D: score=2 STRING: ENSP00000314129
    TNFRSF1BP203332, 3MINT-49445 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0001503ossification IEA--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--


    RPL38 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPL38 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPL38
    Search CenterWatch for drugs/clinical trials and news about RPL38 / RL38 

    Transcripts
    for RPL38 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPL38 gene (2 alternative transcripts): 
    NM_000999.3  NM_001035258.1  

    Unigene Clusters for RPL38:

    Ribosomal protein L38
    Hs.380953  [show with all ESTs], Hs.629060  [show with all ESTs]
    Unigene Representative Sequences: BQ060968, BF676101
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000439590(uc002jka.3) ENST00000311111(uc002jjz.3) ENST00000530646(uc002jjy.1)
    ENST00000529123 ENST00000584577 ENST00000534490 ENST00000528433 ENST00000533498


    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): RPL38
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL38
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate RPL38
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL38 (see all 7)
    OriGene shRNA RFP: RPL38
    OriGene siRNA: RPL38
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL38
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL38 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL38 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): RPL38 (NM_000999)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL38
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL38 
    Primer
    Products:            		Browse OriGene genome-wide validated SYBR primer pairs
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RPL38
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL38
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL38

    Additional cDNA sequence: AB055771.1 

    24/65 DOTS entries (see all 65):

    DT.92463116  DT.75144110  DT.95119317  DT.100746033  DT.87018371  DT.97868495  DT.120970800  DT.120970760 
    DT.87018407  DT.438387  DT.100060144  DT.100745864  DT.100871490  DT.95119332  DT.95119418  DT.100745933 
    DT.87014732  DT.91835243  DT.87077793  DT.100060138  DT.120970776  DT.120970783  DT.100745931  DT.120970811 

    24/1748 AceView cDNA sequences (see all 1748):

    W92362 AA328215 AA314720 AA858113 F30661 CB117452 AA047012 AI694988 
    BQ549648 BQ931573 AI709294 AI052105 BF445005 AW163639 CB128529 AI460126 
    BE645836 AI934624 BF127568 BE733794 AI709318 CA314107 AI680651 BE217955 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for RPL38 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d
    SP1:                                      -     -                 -     -     -     -                 -                           
    SP2:                                            -                 -     -     -     -                 -                           
    SP3:                                            -                 -     -     -     -                 -     -                     
    SP4:                                                              -     -     -     -                 -                           
    SP5:                                            -                 -     -     -     -                                             


    ECgene alternative splicing isoforms for RPL38

    Expression
    for RPL38 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL38 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTCGGAAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPL38 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Endoderm-like cells (Generation of hepato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPL38 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL38

    SOURCE GeneReport for Unigene clusters: Hs.380953 Hs.629060
        SABiosciences Custom PCR Arrays for RPL38
    Primer
    Products:    		Browse OriGene genome-wide validated SYBR primer pairs
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RPL38
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL38
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL38
    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPL38

    Orthologs
    for RPL38 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL38 gene from 9/33 species (see all 33)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rpl381 , 5 ribosomal protein L381, 5 89.52(n)1
    98.57(a)1    		   11 (79.82 cM)5
    676711  NM_001048057.11  NP_001041522.11 
     1146685245 
    chicken
    (Gallus gallus)    		 Aves RPL381 ribosomal protein L38 84.76(n)
    100(a)    		   771528  XM_001233635.1  XP_001233636.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPL386
    		 --
    		 99(a)
    		 1 ↔ 1
    		 2(98102868-98106230)
    African clawed frog
    (Xenopus laevis)    		 Amphibia 480146012   -- 83.12(n)    48014601 
    zebrafish
    (Danio rerio)    		 Actinopterygii rpl381 ribosomal protein L38 84.76(n)
    100(a)    		   436759  NM_001002486.1  NP_001002486.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpL381 Ribosomal protein L38 65.24(n)
    72.86(a)    		   3355144  NM_001042975.1  NP_001036440.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea rpl-381 Protein RPL-38 74.29(n)
    78.57(a)    		   180044  NM_074459.3  NP_506860.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G434601 60S ribosomal protein L38 71.98(n)
    78.26(a)    		   818947  NM_129907.2  NP_181874.1 
    rice
    (Oryza sativa)    		 Liliopsida Os05g05072001 hypothetical protein 70.05(n)
    75.36(a)    		   4339261  NM_001062525.1  NP_001055990.1 


    ENSEMBL Gene Tree for RPL38 (if available)
    TreeFam Gene Tree for RPL38 (if available) 

    Paralogs
    for RPL38 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL38 gene

    RPL38 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for RPL38
    PGOHUM00000240476 PGOHUM00000240693 PGOHUM00000237691 PGOHUM00000237808 PGOHUM00000245535


    Genomic Variants
    for RPL38 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/236 NCBI SNPs in RPL38 are shown (see all 236)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1150499101,2
    		--72197799(+) GAGAGT/GTATCG 2 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1438253421,2
    		--72197876(+) CTGTTA/GTCCTA 2 -- us2k10--------
    rs1141132991,2
    		C,F,--72197896(+) GGGGCC/TGAGGC 2 -- us2k12Minor allele frequency- T:0.03WA NS 266
    rs285041381,2
    		C,F,--72197981(+) TAAAAA/CATTAA 2 -- us2k1 tfbs31Minor allele frequency- C:0.01NS 148
    rs1387584491,2
    		--72198085(+) GCAACA/GTAAGT 2 -- us2k10--------
    rs1494066031,2
    		--72198110(+) CCTGCC/TTGAAA 2 -- us2k10--------
    rs1447691801,2
    		--72198114(+) CCTGAA/TAAAGG 2 -- us2k10--------
    rs739971291,2
    		C,--72198196(+) NNNNCA/GGAAAG 2 -- us2k14Minor allele frequency- G:0.10WA NA NS 370
    rs1138203281,2
    		C,--72198254(+) AGGAGC/TAGTGG 2 -- us2k13Minor allele frequency- T:0.02CSA WA NS 262
    rs1846872191,2
    		--72198313(+) AGCCGC/GGCTCT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL38 (72199721 - 72206794 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for RPL38
         4 CNVs: 34522 8852 53066 5336

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPL38
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL38

    Disorders / Diseases
    for RPL38 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPL38 for disorders           About GeneDecksing

    OMIM gene information: 604182    OMIM disorders: --

    8 diseases for RPL38:    About MalaCards
    diamond-blackfan anemia    otitis media    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    rhabdomyosarcoma    anemia    pancreatitis    malaria

    1 disease from the University of Copenhagen DISEASES database for RPL38:
    Diamond-Blackfan anemia

    Export disorders for RPL38 gene to outside databases

    Publications
    for RPL38 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL38 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with RPL38)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (1998)
    2. Primary sequence of the human, lysine-rich, ribosomal protein RPL38 and detection of an unusual RPL38 processed pseudogene in the promoter region of the type-1 angiotensin II receptor gene. (PubMed id 9375793)1, 2, 9 Espinosa L.... Navarro E. (1997)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. Shotgun proteomics and network analysis of ubiquitin-r elated proteins from human breast carcinoma epithelial cells. (PubMed id 21853274)1 Zhou J....Liang S. (2012)
    8. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    External Searches for RPL38 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RPL38 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6169 HGNC: 10349 AceView: RPL38 Ensembl:ENSG00000172809 euGenes: HUgn6169
    ECgene: RPL38 Kegg: 6169 H-InvDB: RPL38

    Other Databases showing RPL38 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPL38 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL38 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPL38 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPL38 gene:
    Search GeneIP for patents involving RPL38

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for RPL38 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for RPL38  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL38   Browse OriGene genome-wide validated SYBR primer pairs  
     OriGene Protein Over-expression Lysate for RPL38   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for RPL38   OriGene 3'-UTR Clone for RPL38  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL38   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL38  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for RPL38   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPL38   OriGene Custom Protein Services for RPL38  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPL38
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPL38
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL38
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL38
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL38
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL38
     GenScript Custom Purified and Recombinant Proteins Services for RPL38 GenScript cDNA clones with any tag delivered in your preferred vector for RPL38
     GenScript Custom Assay Services for RPL38 GenScript Custom Superior Antibodies Services for RPL38
     GenScript Custom overexpressing Cell Line Services for RPL38 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RPL38 promoter
     Search Chromatin IP Primers for RPL38
     RT2 qPCR Primer Assay in human, mouse / rat RPL38
     Search GNC Networks for RPL38
     SABiosciences Custom PCR Arrays for RPL38
     Search Tocris compounds for RPL38
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RPL38 proteins
     RPL38 lysates
     Search for Antibodies for RPL38 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for RPL38
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     RPL38 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for RPL38
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPL38
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RPL38
     SwitchGear Promoter luciferase reporter plasmids for RPL38
     Search ThermoFisher Antibodies for RPL38
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL38
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      RPL38 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4