Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RPL37A Gene

protein-coding   GIFtS: 60
GCID: GC02P217327

Ribosomal Protein L37a

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Ribosomal Protein L37a1 2
60S Ribosomal Protein L37a2
L37A2

External Ids:    HGNC: 103481   Entrez Gene: 61682   Ensembl: ENSG000001977567   OMIM: 6133145   UniProtKB: P615133   

Export aliases for RPL37A gene to outside databases

Previous GC identifers: GC02P215460 GC02P216084 GC02P217566 GC02P217189 GC02P217071 GC02P209217


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for RPL37A Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family
of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As
is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed
through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL37A Gene:
RPL37A (ribosomal protein L37a) is a protein-coding gene. Diseases associated with RPL37A include influenza, and breast cancer. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for RPL37A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL37A gene promoter:
         STAT1   AML1a   STAT1beta   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Nkx2-5   POU3F2   STAT1alpha   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL37A promoter sequence
   Search Chromatin IP Primers for RPL37A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL37A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35   Ensembl cytogenetic band:  2q35   HGNC cytogenetic band: 2q35

RPL37A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL37A gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P217327:  view genomic region     (about GC identifiers)

Start:
217,362,912 bp from pter      End:
217,443,903 bp from pter
Size:
80,992 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RL37A_HUMAN, P61513 (See protein sequence)
Recommended Name: 60S ribosomal protein L37a  
Size: 92 amino acids; 10275 Da
1 PDB 3D structure from and Proteopedia for RPL37A:
3J3B (3D)    
Secondary accessions: P12751 Q6FGF5

Explore the universe of human proteins at neXtProt for RPL37A: NX_P61513

Explore proteomics data for RPL37A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RPL37A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000989.1  
    ENSEMBL proteins: 
     ENSP00000418082   ENSP00000470348   ENSP00000388690   ENSP00000410080   ENSP00000410240  
     ENSP00000469607   ENSP00000472653   ENSP00000471102  
    Reactome Protein details: P61513

    RPL37A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for RPL37A
    OriGene Protein Over-expression Lysate for RPL37A
    OriGene Custom MassSpec
    OriGene Custom Protein Services for RPL37A
    GenScript Custom Purified and Recombinant Proteins Services for RPL37A
    Novus Biologicals RPL37A Proteins
    Novus Biologicals RPL37A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPL37A

    RPL37A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for RPL37A
    OriGene Custom Antibody Services for RPL37A
    Novus Biologicals RPL37A Antibodies
    Abcam antibodies for RPL37A
    Cloud-Clone Corp. Antibodies for RPL37A
    ThermoFisher Antibodies for RPL37A
    LSBio Antibodies in human, mouse, rat for RPL37A

    RPL37A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RPL37A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPL37A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RPL37A
    Cloud-Clone Corp. CLIAs for RPL37A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RPL: L ribosomal proteins

    3 InterPro protein domains:
     IPR011331 Ribosomal_L37ae/L37e
     IPR011332 Ribosomal_zn-bd
     IPR002674 Ribosomal_L37ae

    Graphical View of Domain Structure for InterPro Entry P61513

    ProtoNet protein and cluster: P61513

    1 Blocks protein domain: IPB002674 Ribosomal L37ae protein

    UniProtKB/Swiss-Prot: RL37A_HUMAN, P61513
    Similarity: Belongs to the ribosomal protein L37Ae family


    RPL37A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0044822poly(A) RNA binding IDA--
    GO:0046872metal ion binding IEA--
         
    RPL37A for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for RPL37A:
     Decreased viability of wild-ty  Increased S DNA content, incre  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL37A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL37A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL37A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL37A

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL37A:
    hsa-mir-31-5p (MIRT049877), hsa-mir-615-3p (MIRT039731), hsa-mir-99a-5p (MIRT048692), hsa-mir-106b-3p (MIRT038552), hsa-mir-766-3p (MIRT039039)

    Block miRNA regulation of human, mouse, rat RPL37A using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate RPL37A:
    hsa-miR-1273d hsa-miR-660
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RPL37A
    Predesigned siRNA for gene silencing in human, mouse, rat RPL37A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RPL37A

    Clone
    Products:
         
    OriGene clones in human, mouse for RPL37A (see all 8)
    OriGene ORF clones in mouse, rat for RPL37A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL37A (NM_000998)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL37A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RPL37A
    Browse ESI BIO Cell Lines and PureStem Progenitors for RPL37A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    extracellular2
    nucleus1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325
    GO:0070062extracellular vesicular exosome IDA--

    RPL37A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for RPL37A About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL37A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL37A
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL37A (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL37A):
        Ribosome


    RPL37A for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL37A
    Interactions:

        Search GeneGlobe Interaction Network for RPL37A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL37A (P615131, 2, 3 ENSP000004180824) via UniProtKB, MINT, STRING, and/or I2D (see all 411)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL26P612542, 3, ENSP000002938424MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000293842
    RPL35P427662, 3, ENSP000002594694MINT-6489539 MINT-6488791 I2D: score=1 STRING: ENSP00000259469
    TCP1P179872, 3, ENSP000003173344MINT-6488791 I2D: score=1 STRING: ENSP00000317334
    LRIF1Q5T3J32, 3MINT-63938 I2D: score=4 
    GNL3Q9BVP22, 3MINT-6488791 I2D: score=2 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL37A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL37A (RL37A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RPL37A gene: 
    NM_000998.4  

    Unigene Cluster for RPL37A:

    Ribosomal protein L37a
    Hs.433701  [show with all ESTs]
    Unigene Representative Sequence: BC067789
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491306(uc002vgf.3) ENST00000478153 ENST00000490649(uc002vgg.3)
    ENST00000487233 ENST00000600880 ENST00000446558 ENST00000420712 ENST00000359681
    ENST00000456586 ENST00000598925 ENST00000427280 ENST00000441179
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RPL37A using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate RPL37A:
    hsa-miR-1273d hsa-miR-660
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RPL37A
    Predesigned siRNA for gene silencing in human, mouse, rat RPL37A
    Clone
    Products:
         
    OriGene clones in human, mouse for RPL37A (see all 8)
    OriGene ORF clones in mouse, rat for RPL37A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL37A (NM_000998)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL37A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RPL37A
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL37A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL37A
      QuantiTect SYBR Green Assays in human, mouse, rat RPL37A
      QuantiFast Probe-based Assays in human, mouse, rat RPL37A

    Additional mRNA sequence: 

    AK023419.1 AK289472.1 AK291857.1 BC000555.2 BC014262.2 BC016748.2 BC039030.1 BC047872.1 
    BC063476.1 BC067789.1 BC082239.1 CR542152.1 L06499.1 L22154.1 X66699.1 

    Selected DOTS entries (see all 81):

    DT.101962931  DT.100763566  DT.102839462  DT.100716458  DT.100742638  DT.95244961  DT.91781656  DT.97868417 
    DT.100771718  DT.100771498  DT.100716454  DT.91820585  DT.101986819  DT.91781639  DT.100716438  DT.95244944 
    DT.91859312  DT.100716455  DT.120948430  DT.120948353  DT.100801652  DT.100716448  DT.100716456  DT.87000712 

    Selected AceView cDNA sequences (see all 2129):

    CD106468 F24717 AA885786 F20360 AA766892 BE675512 AJ572906 F37261 
    BM887738 BU856831 BG481601 F27179 F15718 AA316785 BF685714 BE907416 
    AI393885 BG385432 BQ950200 BE904009 AI718350 F30048 BM875415 BE877258 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RPL37A    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b
    SP1:                    -           -           -     -               
    SP2:                    -           -                                 
    SP3:                                -           -     -               
    SP4:                                            -     -               
    SP5:                                -                                 


    ECgene alternative splicing isoforms for RPL37A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RPL37A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGACAGTGG
    RPL37A Expression
    About this image


    RPL37A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Thymus (Hematopoietic System)
             Double Negative 2 Thymocytes Thymus
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Blood (Cardiovascular System)
             Double Negative 2 Thymocytes Thymus
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
    RPL37A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL37A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.433701
        Custom PCR Arrays for RPL37A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RPL37A
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL37A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL37A
    QuantiTect SYBR Green Assays in human, mouse, rat RPL37A
    QuantiFast Probe-based Assays in human, mouse, rat RPL37A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL37A gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl37a1 , 5 ribosomal protein L37a1, 5 90.58(n)1
    100(a)1
      1 (36.87 cM)5
    199811  NM_009084.41  NP_033110.11 
     727112605 
    chicken
    (Gallus gallus)
    Aves RPL37A1 ribosomal protein L37a 83.7(n)
    98.91(a)
      769981  NM_001079493.1  NP_001072961.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    98(a)
    81(a)
    many → 1
    many → 1
    GL343674.1(85361-88124)
    GL344171.1(65822-66097)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC642822 hypothetical protein MGC64282 82.47(n)    BC044010.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1717721 zgc:171772 81.88(n)
    96.74(a)
      572109  NM_001105526.1  NP_001098996.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL37a3
    RpL37A1
    protein biosynthesis structural
    constituent of more3
    Ribosomal protein L37A1
    76(a)3
    71.38(n)1
    76.09(a)1
      25C43
    447831  NM_164628.31  NP_723060.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-431 rpl-43 67.03(n)
    71.43(a)
      175070  NM_064556.5  NP_496957.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL43A1 RPL43A 64.47(n)
    67.03(a)
      856156   NP_015368.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G109501 AT3G10950 59.85(n)
    69.32(a)
      820266  NM_111932.1  NP_187706.1 
    rice
    (Oryza sativa)
    Liliopsida AT003365.12   -- 69.33(n)    AT003365.1 


    ENSEMBL Gene Tree for RPL37A (if available)
    TreeFam Gene Tree for RPL37A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RPL37A gene
    1 SIMAP similar gene for RPL37A using alignment to 7 protein entries:     RL37A_HUMAN (see all proteins):
    RPL37L

    RPL37A for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPL37A (see all 10)
    PGOHUM00000250390 PGOHUM00000242623 PGOHUM00000239355 PGOHUM00000247540 PGOHUM00000245531


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for RPL37A (see all 31)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1883442011,2
    --217365518(+) TTTTAC/TGGTAA 1 -- int10--------
    rs1473211811,2
    C--217365595(+) AATCAC/TTGTTC 1 -- int10--------
    rs1809207241,2
    --217365604(+) TCTCAC/TTGTAT 1 -- int10--------
    rs778895601,2
    F--217365648(+) CCATTC/GCCTTT 1 -- int11Minor allele frequency- G:0.03EA 120
    rs1857950451,2
    C--217365656(+) TTTTAA/CTAAGT 1 -- int10--------
    rs582482081,2
    C,F--217365746(+) TACTTA/TTAAAA 1 -- int12Minor allele frequency- T:0.16WA EA 238
    rs1914881131,2
    --217365873(+) CCGAGA/GAGTAA 1 -- int10--------
    rs1828558411,2
    --217365954(+) CTTTCC/TAGGAA 1 -- int10--------
    rs1488075581,2
    --217366024(+) TGTTAA/TCATGC 1 -- int10--------
    rs1162252101,2
    C,F--217366061(+) CTTTCC/TAGTAC 1 -- int11Minor allele frequency- T:0.02WA 118

    HapMap Linkage Disequilibrium report for RPL37A (217362912 - 217443903 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RPL37A: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing RPL37A
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL37A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613314    OMIM disorders: --

    3 diseases for RPL37A:    
    About MalaCards
    influenza    breast cancer    malaria


    RPL37A for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPL37A

    Export disorders for RPL37A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RPL37A gene, integrated from 10 sources (see all 33):
    (articles sorted by number of sources associating them with RPL37A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Primary sequence of the human ribosomal protein L37a. (PubMed id 1437567)1, 2, 3, 9 Hoof T.... Tuemmler B. (Nucleic Acids Res. 1992)
    2. Human ribosomal protein L37a: cloning of the cDNA and analysis of differential gene expression in tissues and cell lines. (PubMed id 8224875)1, 2, 9 Saha D.P.... Howells R.D. (Gene 1993)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    7. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. (PubMed id 23246001)1 Xu Y....Ye Y. (Cell Rep 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 6168 HGNC: 10348 AceView: RPL37A Ensembl:ENSG00000197756 euGenes: HUgn6168
    ECgene: RPL37A Kegg: 6168 H-InvDB: RPL37A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RPL37A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RPL37A gene:
    Search GeneIP for patents involving RPL37A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for RPL37A   OriGene RNAi products in human, mouse, rat for RPL37A  
     OriGene qPCR primer pairs and template standards for RPL37A   OriGene Protein Over-expression Lysate for RPL37A  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RPL37A  
     OriGene qSTAR qPCR primer pairs in human, mouse for RPL37A   OriGene Purified Protein for RPL37A  
     OriGene ORF clones in mouse, rat for RPL37A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPL37A   OriGene Custom Protein Services for RPL37A  

     
     
     Block miRNA regulation of human, mouse, rat RPL37A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RPL37A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL37A Predesigned siRNA for gene silencing in human, mouse, rat RPL37A
     QuantiFast Probe-based Assays in human, mouse, rat RPL37A QuantiTect SYBR Green Assays in human, mouse, rat RPL37A
     Custom PCR Arrays for RPL37A Search Chromatin IP Primers for RPL37A
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL37A  Search GeneGlobe Interaction Network for RPL37A
     Regulatory tfbs in RPL37A promoter
     GenScript Custom Purified and Recombinant Proteins Services for RPL37A GenScript cDNA clones with any tag delivered in your preferred vector for RPL37A
     GenScript Custom Assay Services for RPL37A GenScript Custom overexpressing Cell Line Services for RPL37A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RPL37A (RL37A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RPL37A antibodies
     RPL37A proteins
     RPL37A lysates
     Antibodies for RPL37A
     See all of Abcam's Antibodies, Kits and Proteins for RPL37A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RPL37A
     Antibodies for RPL37A
     ELISAs for RPL37A
     CLIAs for RPL37A



     Browse ESI BIO Cell Lines and PureStem Progenitors for RPL37A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37A
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RPL37A
     SwitchGear Promoter luciferase reporter plasmids for RPL37A
     ThermoFisher Antibodies for RPL37A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL37A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL37A
     LSBio Antibodies in human, mouse, rat for RPL37A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RPL37A gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4