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Aliases for RPL37A Gene

Aliases for RPL37A Gene

  • Ribosomal Protein L37a 2 3
  • 60S Ribosomal Protein L37a 3
  • L37A 3

External Ids for RPL37A Gene

Summaries for RPL37A Gene

Entrez Gene Summary for RPL37A Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

GeneCards Summary for RPL37A Gene

RPL37A (Ribosomal Protein L37a) is a Protein Coding gene. Among its related pathways are Disease and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for RPL37A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL37A Gene

Genomics for RPL37A Gene

Genomic Location for RPL37A Gene

Start:
216,498,189 bp from pter
End:
216,579,180 bp from pter
Size:
80,992 bases
Orientation:
Plus strand

Genomic View for RPL37A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPL37A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL37A Gene

Regulatory Elements for RPL37A Gene

Proteins for RPL37A Gene

  • Protein details for RPL37A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P61513-RL37A_HUMAN
    Recommended name:
    60S ribosomal protein L37a
    Protein Accession:
    P61513
    Secondary Accessions:
    • P12751
    • Q6FGF5

    Protein attributes for RPL37A Gene

    Size:
    92 amino acids
    Molecular mass:
    10275 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPL37A Gene

neXtProt entry for RPL37A Gene

Proteomics data for RPL37A Gene at MOPED

Post-translational modifications for RPL37A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RPL37A Gene

No data available for DME Specific Peptides for RPL37A Gene

Domains for RPL37A Gene

Gene Families for RPL37A Gene

HGNC:
  • RPL :L ribosomal proteins

Protein Domains for RPL37A Gene

UniProtKB/Swiss-Prot:

RL37A_HUMAN
Family:
  • Belongs to the ribosomal protein L37Ae family.:
    • P61513
genes like me logo Genes that share domains with RPL37A: view

Function for RPL37A Gene

Gene Ontology (GO) - Molecular Function for RPL37A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome NAS 12962325
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22681889
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RPL37A: view
genes like me logo Genes that share phenotypes with RPL37A: view

miRNA for RPL37A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RPL37A Gene

Localization for RPL37A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RPL37A Gene COMPARTMENTS Subcellular localization image for RPL37A gene
Compartment Confidence
cytosol 5
extracellular 2
nucleus 1

Gene Ontology (GO) - Cellular Components for RPL37A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA 21630459
GO:0005829 cytosol TAS --
GO:0005840 ribosome --
GO:0005925 focal adhesion IDA 21423176
genes like me logo Genes that share ontologies with RPL37A: view

Pathways for RPL37A Gene

genes like me logo Genes that share pathways with RPL37A: view

Pathways by source for RPL37A Gene

1 GeneGo (Thomson Reuters Life Sciences Research) pathway for RPL37A Gene
1 BioSystems pathway for RPL37A Gene

Gene Ontology (GO) - Biological Process for RPL37A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0006412 translation TAS --
GO:0006413 translational initiation TAS --
GO:0006414 translational elongation TAS --
GO:0006415 translational termination TAS --
genes like me logo Genes that share ontologies with RPL37A: view

Transcripts for RPL37A Gene

mRNA/cDNA for RPL37A Gene

Unigene Clusters for RPL37A Gene

Ribosomal protein L37a:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RPL37A Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b
SP1: - - - -
SP2: - -
SP3: - - -
SP4: - -
SP5: -

Relevant External Links for RPL37A Gene

GeneLoc Exon Structure for
RPL37A
ECgene alternative splicing isoforms for
RPL37A

Expression for RPL37A Gene

mRNA expression in normal human tissues for RPL37A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RPL37A Gene

SOURCE GeneReport for Unigene cluster for RPL37A Gene Hs.433701

genes like me logo Genes that share expressions with RPL37A: view

Orthologs for RPL37A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPL37A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RPL37A 36
  • 100 (n)
  • 100 (a)
RPL37A 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RPL37A 36
  • 89.49 (n)
  • 100 (a)
RPL37A 37
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 90 (a)
OneToMany
-- 37
  • 57 (a)
OneToMany
-- 37
  • 79 (a)
OneToMany
RPL37A 36
  • 89.13 (n)
  • 100 (a)
mouse
(Mus musculus)
Mammalia Rpl37a 36
  • 90.58 (n)
  • 100 (a)
Rpl37a 16
Rpl37a 37
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RPL37A 37
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RPL37A 37
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rpl37a 36
  • 84.78 (n)
  • 91.3 (a)
chicken
(Gallus gallus)
Aves RPL37A 36
  • 83.7 (n)
  • 98.91 (a)
RPL37A 37
  • 99 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 98 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
African clawed frog
(Xenopus laevis)
Amphibia MGC64282 36
tropical clawed frog
(Silurana tropicalis)
Amphibia rpl37a 36
  • 84.42 (n)
  • 97.83 (a)
Str.1005 36
zebrafish
(Danio rerio)
Actinopterygii RPL37A 37
  • 97 (a)
OneToOne
zgc:171772 36
  • 81.88 (n)
  • 96.74 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009920 36
  • 69.66 (n)
  • 74.16 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpL37A 36
  • 71.38 (n)
  • 76.09 (a)
RpL37A 37
  • 76 (a)
OneToOne
RpL37a 38
  • 76 (a)
worm
(Caenorhabditis elegans)
Secernentea rpl-43 36
  • 67.03 (n)
  • 71.43 (a)
rpl-43 37
  • 71 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AGL310C 36
  • 65.57 (n)
  • 67.03 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL43A 36
  • 64.47 (n)
  • 67.03 (a)
RPL43A 37
  • 66 (a)
OneToMany
RPL43B 37
  • 66 (a)
OneToMany
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E05941g 36
  • 62.64 (n)
  • 63.74 (a)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.2253 36
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G10950 36
  • 59.85 (n)
  • 69.32 (a)
rice
(Oryza sativa)
Liliopsida Os05g0557000 36
  • 62.5 (n)
  • 71.59 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU07562 36
  • 62.64 (n)
  • 63.74 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpl4302 36
  • 56.41 (n)
  • 59.34 (a)
Species with no ortholog for RPL37A:
  • Actinobacteria (Mycobacterium tuberculosis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPL37A Gene

ENSEMBL:
Gene Tree for RPL37A (if available)
TreeFam:
Gene Tree for RPL37A (if available)

Paralogs for RPL37A Gene

Selected SIMAP similar genes for RPL37A Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with RPL37A: view

No data available for Paralogs for RPL37A Gene

Variants for RPL37A Gene

Sequence variations from dbSNP and Humsavar for RPL37A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs15522 -- 216,501,441(+) CTATA(A/G)TAAAT utr-variant-3-prime
rs1065702 -- 216,501,388(+) GAAGG(A/G)GTTGA reference, missense
rs1804337 -- 216,501,364(+) GGTAA(A/G)GTCCG reference, missense
rs1804342 -- 216,501,365(+) GTAAA(C/G)TCCGC missense, reference
rs11267044 -- 216,501,388(+) AAGGA(A/G)GTTGA reference, frameshift-variant

Relevant External Links for RPL37A Gene

HapMap Linkage Disequilibrium report
RPL37A

No data available for Structural Variations from Database of Genomic Variants (DGV) for RPL37A Gene

Disorders for RPL37A Gene

Relevant External Links for RPL37A

Genetic Association Database (GAD)
RPL37A
genes like me logo Genes that share disorders with RPL37A: view

No data available for UniProtKB/Swiss-Prot for RPL37A Gene

Publications for RPL37A Gene

  1. Primary sequence of the human ribosomal protein L37a. (PMID: 1437567) Hoof T. … Tuemmler B. (Nucleic Acids Res. 1992) 2 3 4 23
  2. Human ribosomal protein L37a: cloning of the cDNA and analysis of differential gene expression in tissues and cell lines. (PMID: 8224875) Saha D.P. … Howells R.D. (Gene 1993) 3 4 23
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3

Products for RPL37A Gene

Sources for RPL37A Gene

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