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RPL37 Gene

protein-coding   GIFtS: 61
GCID: GC05M040825

Ribosomal Protein L37

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ribosomal Protein L371 2
60S Ribosomal Protein L37a1 2
G1.162 3
60S Ribosomal Protein L372
L372

External Ids:    HGNC: 103471   Entrez Gene: 61672   Ensembl: ENSG000001455927   OMIM: 6041815   UniProtKB: P619273   
ORGUL members:         

Export aliases for RPL37 gene to outside databases

Previous GC identifers: GC05M041139 GC05M041924 GC05M040878 GC05M040876 GC05M040866 GC05M040783


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL37 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family
of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene
dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL37 Gene:
RPL37 (ribosomal protein L37) is a protein-coding gene. GO annotations related to this gene include RNA binding and rRNA binding.

UniProtKB/Swiss-Prot: RL37_HUMAN, P61927
Function: Binds to the 23S rRNA (By similarity)

Gene Wiki entry for RPL37 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NC_018916.2  NT_006576.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL37 gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   E47   YY1   Nkx3-1 v2   HSF2   Nkx3-1 v3   ZID   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL37 promoter sequence
   Search Chromatin IP Primers for RPL37

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13   Ensembl cytogenetic band:  5p13.1   HGNC cytogenetic band: 5p13.1

RPL37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL37 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M040825:  view genomic region     (about GC identifiers)

Start:
40,825,364 bp from pter      End:
40,835,437 bp from pter
Size:
10,074 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RL37_HUMAN, P61927 (See protein sequence)
Recommended Name: 60S ribosomal protein L37  
Size: 97 amino acids; 11078 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
1 PDB 3D structure from and Proteopedia for RPL37:
3J3B (3D)    
Secondary accessions: B2R4H2 P02403 Q6IBB4 Q99883

Explore the universe of human proteins at neXtProt for RPL37: NX_P61927

Explore proteomics data for RPL37 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys31
  • Modification sites at PhosphoSitePlus

  • See RPL37 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000988.1  
    ENSEMBL proteins: 
     ENSP00000274242   ENSP00000422823   ENSP00000426449  
    Reactome Protein details: P61927

    RPL37 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RPL37

     
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    antibodies-online proteins for RPL37 (14 products) 

     
    antibodies-online peptides for RPL37

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    4 InterPro protein domains:
     IPR011331 Ribosomal_L37ae/L37e
     IPR001569 Ribosomal_L37e
     IPR018267 Ribosomal_L37e_CS
     IPR011332 Ribosomal_zn-bd

    Graphical View of Domain Structure for InterPro Entry P61927

    ProtoNet protein and cluster: P61927

    UniProtKB/Swiss-Prot: RL37_HUMAN, P61927
    Similarity: Belongs to the ribosomal protein L37e family


    Find genes that share domains with RPL37           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RL37_HUMAN, P61927
    Function: Binds to the 23S rRNA (By similarity)

         Genatlas biochemistry entry for RPL37:
    60S ribosomal protein L37,11kDa,overexpressed in colon cancer

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS7545944
    GO:0003735structural constituent of ribosome TAS7545944
    GO:0019843rRNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with RPL37           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for RPL37:
     Decreased G3BP1 protein expres  Decreased viability  Decreased viability of wild-ty  Increased S DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPL37

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL37:
    hsa-mir-744-5p (MIRT037660), hsa-mir-191-5p (MIRT045785), hsa-mir-17-5p (MIRT050856), hsa-mir-34a-5p (MIRT047353), hsa-mir-324-5p (MIRT043070)

    Block miRNA regulation of human, mouse, rat RPL37 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RPL37:
    hsa-miR-589* hsa-miR-548c-3p hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidRPL37 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RPL37
    Predesigned siRNA for gene silencing in human, mouse, rat RPL37

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: RPL37 (NM_000997)
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit TAS7545944

    Find genes that share ontologies with RPL37           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL37 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease


    Find genes that share SuperPaths with RPL37           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL37
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL37
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL37 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL37):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL37
    Interactions:

        GeneGlobe Interaction Network for RPL37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL37 (P619271, 3 ENSP000002742424) via UniProtKB, MINT, STRING, and/or I2D (see all 285)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DDX56Q9NY931, 3, ENSP000002587724EBI-2105843,EBI-372376 I2D: score=2 STRING: ENSP00000258772
    HAT1O149293, ENSP000002641084I2D: score=2 STRING: ENSP00000264108
    CCT4P509913, ENSP000003779584I2D: score=1 STRING: ENSP00000377958
    RPL4P365783, ENSP000003114304I2D: score=1 STRING: ENSP00000311430
    TCP1P179873, ENSP000003173344I2D: score=1 STRING: ENSP00000317334
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS7545944
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPL37           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL37 (RL37)

    5 DrugBank Compounds for RPL37    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235
    PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE-- --target--10592235
    Virginiamycin factor S1Virginiamycin factor S (see all 2)23152-29-6target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPL37 gene: 
    NM_000997.4  

    Unigene Clusters for RPL37:

    Ribosomal protein L37
    Hs.447582  [show with all ESTs], Hs.558601  [show with all ESTs]
    Unigene Representative Sequences: BM553029, CD387687
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274242(uc003jme.1) ENST00000511787 ENST00000509877 ENST00000507642
    ENST00000504562 ENST00000508493
    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate RPL37:
    hsa-miR-589* hsa-miR-548c-3p hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidRPL37 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RPL37
    Clone
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    GenScript: all cDNA clones in your preferred vector: RPL37 (NM_000997)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL37
      QuantiTect SYBR Green Assays in human, mouse, rat RPL37
      QuantiFast Probe-based Assays in human, mouse, rat RPL37

    Additional mRNA sequence: 

    BC079477.1 D23661.1 L11567.1 

    Selected DOTS entries (see all 45):

    DT.91812660  DT.100892256  DT.100799842  DT.100892253  DT.101955987  DT.100892238  DT.86994591  DT.120827122 
    DT.120827297  DT.120827221  DT.91800972  DT.120827280  DT.100892229  DT.120827296  DT.98083938  DT.120827317 
    DT.120827310  DT.100892251  DT.95323085  DT.101986545  DT.120827198  DT.320777  DT.92000137  DT.100803711 

    Selected AceView cDNA sequences (see all 2010):

    AI814219 BU186389 AA548413 F31388 F28227 CA337714 CD679002 F27208 
    F32488 BE910563 F35462 AA778709 AA706691 BI768552 F27198 BM746602 
    BM824819 AI097060 CB133621 CA976135 BM744260 BU856433 AA983179 N73103 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RPL37    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b
    SP1:                                                            
    SP2:                                      -     -               
    SP3:                                      -                     
    SP4:              -                                             


    ECgene alternative splicing isoforms for RPL37

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL37 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAATAAATGT
    RPL37 Expression
    About this image

    RPL37 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL37 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.447582 Hs.558601
        Custom PCR Arrays for RPL37
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL37 gene from Selected species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl371 , 5 ribosomal protein L371, 5 92.78(n)1
    100(a)1
      15 (1.99 cM)5
    672811  NM_026069.31  NP_080345.11 
     51166135 
    chicken
    (Gallus gallus)
    Aves RPL371 ribosomal protein L37 83.33(n)
    97.73(a)
      427186  NM_001122763.1  NP_001116235.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL376
    ribosomal protein L37
    97(a)
    1 ↔ 1
    2(6954344-6964534)
    African clawed frog
    (Xenopus laevis)
    Amphibia CB591663.12   -- 98.09(n)    CB591663.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AI106045.12   -- 73.63(n)    AI106045.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90913
    RpL37a1
    protein biosynthesis structural
    constituent of more3
    Ribosomal protein L37a1
    75(a)
    (best of 2)3
    68.94(n)1
    77.27(a)1
      13B13
    324461  NM_001272632.11  NP_001259561.11 
    worm
    (Caenorhabditis elegans)
    Secernentea W01D2.11 W01D2.1 59.39(n)
    64.37(a)
      175141  NM_064671.5  NP_497072.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL37A(YLR185W)4
    RPL37A1
    Protein component of the large (60S) ribosomal subunit, more4
    RPL37A1
    63.18(n)1
    65.12(a)1
      12(522663-523288)4
    8508821, 4  NP_013286.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G523001 AT1G52300 61.69(n)
    70.11(a)
      841660  NM_104109.2  NP_175640.1 
    rice
    (Oryza sativa)
    Liliopsida AK058280.12   -- 74.48(n)    AK058280.1 


    ENSEMBL Gene Tree for RPL37 (if available)
    TreeFam Gene Tree for RPL37 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL37 gene

    Find genes that share paralogs with RPL37           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPL37 (see all 28)
    PGOHUM00000238404 PGOHUM00000238937 PGOHUM00000258568 PGOHUM00000242808 PGOHUM00000239438


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL37 (see all 110)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349764561,2
    C--40780149(+) GATTA-/CAGTTTT 1 -- us2k13Minor allele frequency- CA:0.27CSA NS 156
    rs1909766541,2
    --40782591(+) ATCTCC/TTGACC 1 -- ds50010--------
    rs1840695151,2
    --40782614(+) CACCTC/TGGCCT 1 -- ds50010--------
    rs1162813641,2
    C,F--40831416(+) AAGTAT/CAGTCT 1 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1412953761,2
    C--40831430(+) ATTTCA/GGGAGG 1 -- ut310--------
    rs1450740651,2
    --40831524(+) AAATAC/TAAGAT 1 -- ut310--------
    rs1385303021,2
    F--40831590(+) GATACC/ACTTCC 1 -- ut311Minor allele frequency- A:0.04NS 140
    rs1389343751,2
    --40831601(+) AAGGCC/TAGGTT 1 -- ut310--------
    rs1155541421,2
    C,F--40831779(+) ACAAAA/GAAAAC 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs1159783861,2
    C,F--40831803(+) AATAAA/GCCACG 1 -- ut312Minor allele frequency- G:0.02WA NS 264

    HapMap Linkage Disequilibrium report for RPL37 (40825364 - 40835437 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RPL37:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv880438CNV Loss21882294
    nsv518711CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL37
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604181    OMIM disorders: --


    Find genes that share disorders with RPL37           About GenesLikeMe


    Export disorders for RPL37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL37 gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with RPL37)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. (PubMed id 7545944)1, 2, 3, 9 Barnard G.F.... Chen L.B. (Biochim. Biophys. Acta 1994)
    2. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    3. Cell cycle, differentiation and tissue-independent expression of ribosomal protein L37. (PubMed id 7588717)1, 2, 9 Su S. and Bird R.C. (Eur. J. Biochem. 1995)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (Genome Res. 2002)
    6. CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism. (PubMed id 15485924)1, 9 Schwartz E.I....Maraia R.J. (Mol. Cell. Biol. 2004)
    7. Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network. (PubMed id 23874713)1 Daftuar L....Prives C. (PLoS ONE 2013)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    10. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6167 HGNC: 10347 AceView: RPL37 Ensembl:ENSG00000145592 euGenes: HUgn6167
    ECgene: RPL37 Kegg: 6167 H-InvDB: RPL37

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPL37 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPL37 gene:
    Search GeneIP for patents involving RPL37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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