Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL37 Gene

protein-coding   GIFtS: 60
GCID: GC05M040825

Ribosomal Protein L37

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribosomal Protein L371 2
60S Ribosomal Protein L37a1 2
G1.162 3
60S Ribosomal Protein L372
L372

External Ids:    HGNC: 103471   Entrez Gene: 61672   Ensembl: ENSG000001455927   OMIM: 6041815   UniProtKB: P619273   

Export aliases for RPL37 gene to outside databases

Previous GC identifers: GC05M041139 GC05M041924 GC05M040878 GC05M040876 GC05M040866 GC05M040783


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPL37 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family
of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene
dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL37 Gene: 
RPL37 (ribosomal protein L37) is a protein-coding gene. Diseases associated with RPL37 include echinococcosis, and diamond-blackfan anemia, and among its related super-pathways are Eukaryotic Translation Initiation and Metabolism of RNA. GO annotations related to this gene include RNA binding and rRNA binding.

UniProtKB/Swiss-Prot: RL37_HUMAN, P61927
Function: Binds to the 23S rRNA (By similarity)

Gene Wiki entry for RPL37 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL37 gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   E47   YY1   Nkx3-1 v2   HSF2   Nkx3-1 v3   ZID   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL37 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL37

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13   Ensembl cytogenetic band:  5p13.1   HGNC cytogenetic band: 5p13.1

RPL37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL37 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M040825:  view genomic region     (about GC identifiers)

Start:
40,825,364 bp from pter      End:
40,835,437 bp from pter
Size:
10,074 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RL37_HUMAN, P61927 (See protein sequence)
Recommended Name: 60S ribosomal protein L37  
Size: 97 amino acids; 11078 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
1 PDB 3D structure from and Proteopedia for RPL37:
3J3B (3D)    
Secondary accessions: B2R4H2 P02403 Q6IBB4 Q99883

Explore the universe of human proteins at neXtProt for RPL37: NX_P61927

Explore proteomics data for RPL37 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P61927

  • RPL37 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPL37 Protein Expression
    REFSEQ proteins: NP_000988.1  
    ENSEMBL proteins: 
     ENSP00000274242   ENSP00000422823   ENSP00000426449  
    Reactome Protein details: P61927
    Human Recombinant Protein Products for RPL37: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for RPL37
    GenScript Custom Purified and Recombinant Proteins Services for RPL37
    Novus Biologicals RPL37 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPL37 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit TAS7545944

    RPL37 for ontologies           About GeneDecksing



    RPL37 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for RPL37
    OriGene Custom Antibody Services for RPL37
    GenScript Custom Superior Antibodies Services for RPL37
    Novus Biologicals RPL37 Antibodies
    Abcam antibodies for RPL37
    Cloud-Clone Corp. Antibodies for RPL37 
    ThermoFisher Antibodies for RPL37
    LSBio Antibodies in human, mouse, rat for RPL37 

    Assay Products for RPL37: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RPL37
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPL37
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RPL37 
    Cloud-Clone Corp. CLIAs for RPL37


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RPL: L ribosomal proteins

    4 InterPro protein domains:
     IPR011331 Ribosomal_L37ae/L37e
     IPR001569 Ribosomal_L37e
     IPR018267 Ribosomal_L37e_CS
     IPR011332 Ribosomal_zn-bd_dom

    Graphical View of Domain Structure for InterPro Entry P61927

    ProtoNet protein and cluster: P61927

    UniProtKB/Swiss-Prot: RL37_HUMAN, P61927
    Similarity: Belongs to the ribosomal protein L37e family


    RPL37 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RL37_HUMAN, P61927
    Function: Binds to the 23S rRNA (By similarity)

         Genatlas biochemistry entry for RPL37:
    60S ribosomal protein L37,11kDa,overexpressed in colon cancer

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS7545944
    GO:0003735structural constituent of ribosome TAS7545944
    GO:0019843rRNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    RPL37 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for RPL37:
     Decreased G3BP1 protein expres  Decreased viability  Decreased viability of wild-ty  Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPL37 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RPL37

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL37 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL37 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL37
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate RPL37:
    hsa-miR-589* hsa-miR-548c-3p hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidRPL37 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RPL37
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL37

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RPL37
    Sirion Biotech Customized adenovirus for overexpression of RPL37

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for RPL37 (see all 5)
    OriGene ORF clones in mouse, rat for RPL37
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL37 (NM_000997)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL37
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37
    Sirion Biotech Customized lentivirus for stable overexpression of RPL37 
                         Customized lentivirus expression plasmids for stable overexpression of RPL37 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RPL37
    Search LifeMap BioReagents cell lines for RPL37
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RPL37 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Viral mRNA Translation
    Influenza Life Cycle0.95
    3' -UTR-mediated translational regulation0.93
    Influenza Infection0.95
    L13a-mediated translational silencing of Ceruloplasmin expression0.93
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Formation of a pool of free 40S subunits0.90
    Eukaryotic Translation Termination0.94
    Nonsense-Mediated Decay0.84
    2Metabolism of mRNA
    Metabolism of mRNA0.92
    Metabolism of RNA0.92
    3Generic Transcription Pathway
    Gene Expression0.47
    4Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL37
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL37
        Cytoplasmic Ribosomal Proteins

    5/23        Reactome Pathways for RPL37 (see all 23)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL37):
        Ribosome


    RPL37 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPL37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/203 Interacting proteins for RPL37 (P619271, 3 ENSP000002742424) via UniProtKB, MINT, STRING, and/or I2D (see all 203)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DDX56Q9NY931, 3, ENSP000002587724EBI-2105843,EBI-372376 I2D: score=2 STRING: ENSP00000258772
    CCT4P509913, ENSP000003779584I2D: score=1 STRING: ENSP00000377958
    GNB2L1P632443, ENSP000003660134I2D: score=1 STRING: ENSP00000366013
    RPL17P186213I2D: score=1 
    RPL17-C18orf32P186213I2D: score=1 
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS7545944
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL37 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPL37 (RL37)

    5 DrugBank Compounds for RPL37    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235
    PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE-- --target--10592235
    Virginiamycin factor S1Virginiamycin factor S (see all 2)23152-29-6target--10592235

    Search CenterWatch for drugs/clinical trials and news about RPL37 / RL37

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPL37 gene: 
    NM_000997.4  

    Unigene Clusters for RPL37:

    Ribosomal protein L37
    Hs.447582  [show with all ESTs], Hs.558601  [show with all ESTs], Hs.731513  [show with all ESTs]
    Unigene Representative Sequences: BM553029, CD387687, BX647123
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274242(uc003jme.1) ENST00000511787 ENST00000509877 ENST00000507642
    ENST00000504562 ENST00000508493
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL37
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate RPL37:
    hsa-miR-589* hsa-miR-548c-3p hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidRPL37 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RPL37
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL37
    Clone
    Products:
         
    OriGene clones in human, mouse for RPL37 (see all 5)
    OriGene ORF clones in mouse, rat for RPL37
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL37 (NM_000997)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL37
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37
    Sirion Biotech Customized lentivirus for stable overexpression of RPL37 
                         Customized lentivirus expression plasmids for stable overexpression of RPL37 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RPL37
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL37
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPL37
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL37
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL37

    Additional mRNA sequence: 

    AK311827.1 BC067790.1 BC084576.1 BX647123.1 CR456890.1 

    24/73 DOTS entries (see all 73):

    DT.91812660  DT.100892256  DT.100799842  DT.101955987  DT.100892238  DT.100892253  DT.86994591  DT.120827297 
    DT.120827122  DT.120827221  DT.98083938  DT.120827317  DT.91800972  DT.120827296  DT.100803711  DT.100892229 
    DT.120827280  DT.320777  DT.91999919  DT.120827310  DT.92000149  DT.100892251  DT.95323085  DT.120827198 

    24/2010 AceView cDNA sequences (see all 2010):

    AI814219 BU186389 AA548413 F31388 F28227 CA337714 CD679002 F27208 
    F32488 BE910563 F35462 AA778709 AA706691 BI768552 F27198 BM746602 
    BM824819 AI097060 CB133621 CA976135 BM744260 BU856433 AA983179 N73103 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RPL37    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b
    SP1:                                                            
    SP2:                                      -     -               
    SP3:                                      -                     
    SP4:              -                                             


    ECgene alternative splicing isoforms for RPL37

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL37 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAATAAATGT
    RPL37 Expression
    About this image


    See RPL37 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL37

    SOURCE GeneReport for Unigene clusters: Hs.447582 Hs.558601 Hs.731513
        SABiosciences Custom PCR Arrays for RPL37
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RPL37
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL37
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPL37
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL37
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL37
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL37 gene from 9/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl375
    Gm138261
    ribosomal protein L375
    predicted gene 138261
    93.13(n)1
    100(a)1
      15 (1.99 cM)5
    1005028251  XM_003085347.21  XP_003085395.11 
     51166135 
    chicken
    (Gallus gallus)
    Aves RPL371 ribosomal protein L37 84.19(n)
    97.94(a)
      427186  NM_001122763.1  NP_001116235.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL376
    ribosomal protein L37
    97(a)
    1 ↔ 1
    2(6954344-6964534)
    African clawed frog
    (Xenopus laevis)
    Amphibia CB591663.12   -- 98.09(n)    CB591663.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AI106045.12   -- 73.63(n)    AI106045.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90913 protein biosynthesis structural
    constituent of more
    75(a)
    (best of 2)
      13B1   --
    worm
    (Caenorhabditis elegans)
    Secernentea W01D2.16
    rpl-376
    60S ribosomal protein L37
    61(a)
    59(a)
    many → 1
    many → 1
    II(14815516-14816212)
    III(3528547-3528968)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL37A(YLR185W)4 Protein component of the large (60S) ribosomal subunit, more   --   12(522663-523288) 850882  NP_013286.1 
    rice
    (Oryza sativa)
    Liliopsida AK058280.12   -- 74.48(n)    AK058280.1 


    ENSEMBL Gene Tree for RPL37 (if available)
    TreeFam Gene Tree for RPL37 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL37 gene

    RPL37 for paralogs           About GeneDecksing


    5/28 Pseudogenes.org Pseudogenes for RPL37 (see all 28)
    PGOHUM00000238404 PGOHUM00000238937 PGOHUM00000258568 PGOHUM00000242808 PGOHUM00000239438


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/110 SNPs in RPL37 are shown (see all 110)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0146064
    ----see VAR_0146062 G E mis40--------
    rs349764561,2
    C--40780149(+) GATTA-/CAGTTTT 1 -- us2k13Minor allele frequency- CA:0.27CSA NS 156
    rs1909766541,2
    --40782591(+) ATCTCC/TTGACC 1 -- ds50010--------
    rs1840695151,2
    --40782614(+) CACCTC/TGGCCT 1 -- ds50010--------
    rs1162813641,2
    C,F--40831416(+) AAGTAT/CAGTCT 1 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1412953761,2
    C--40831430(+) ATTTCA/GGGAGG 1 -- ut310--------
    rs1450740651,2
    --40831524(+) AAATAC/TAAGAT 1 -- ut310--------
    rs1385303021,2
    F--40831590(+) GATACC/ACTTCC 1 -- ut311Minor allele frequency- A:0.04NS 140
    rs1389343751,2
    --40831601(+) AAGGCC/TAGGTT 1 -- ut310--------
    rs1155541421,2
    C,F--40831779(+) ACAAAA/GAAAAC 1 -- ut311Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for RPL37 (40825364 - 40835437 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RPL37:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv880438CNV Loss21882294
    nsv518711CNV Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL37
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL37

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604181    OMIM disorders: --

    5 diseases for RPL37:    About MalaCards
    echinococcosis    diamond-blackfan anemia    anemia    influenza
    colon cancer


    RPL37 for disorders           About GeneDecksing


    Export disorders for RPL37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL37 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with RPL37)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. (PubMed id 7545944)1, 2, 3, 9 Barnard G.F.... Chen L.B. (1994)
    2. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (1998)
    3. Cell cycle, differentiation and tissue-independent expression of ribosomal protein L37. (PubMed id 7588717)1, 2, 9 Su S. and Bird R.C. (1995)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2 Yoshihama M.... Kenmochi N. (2002)
    6. CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism. (PubMed id 15485924)1, 9 Schwartz E.I....Maraia R.J. (2004)
    7. Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network. (PubMed id 23874713)1 Daftuar L....Prives C. (2013)
    8. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    9. The P-body component USP52/PAN2 is a novel regulator o f HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6167 HGNC: 10347 AceView: RPL37 Ensembl:ENSG00000145592 euGenes: HUgn6167
    ECgene: RPL37 Kegg: 6167 H-InvDB: RPL37

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL37 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPL37 gene:
    Search GeneIP for patents involving RPL37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for RPL37   OriGene RNAi products in human, mouse, rat for RPL37  
     OriGene qPCR primer pairs and template standards for RPL37   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RPL37  
     OriGene qSTAR qPCR primer pairs in human, mouse for RPL37   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RPL37   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPL37   OriGene Custom Protein Services for RPL37  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPL37
     QIAGEN SeqTarget long-range PCR primers for resequencing RPL37
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL37
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL37
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL37
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL37
     GenScript Custom Purified and Recombinant Proteins Services for RPL37 GenScript cDNA clones with any tag delivered in your preferred vector for RPL37
     GenScript Custom Assay Services for RPL37 GenScript Custom Superior Antibodies Services for RPL37
     GenScript Custom overexpressing Cell Line Services for RPL37 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RPL37 promoter
     Search Chromatin IP Primers for RPL37
     RT2 qPCR Primer Assay in human, mouse, rat RPL37
     GNC Network for RPL37
     SABiosciences Custom PCR Arrays for RPL37
     Search Tocris compounds for RPL37 (RL37)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RPL37 antibodies
     RPL37 proteins
     Antibodies for RPL37
     See all of Abcam's Antibodies, Kits and Proteins for RPL37
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for RPL37
     Antibodies for RPL37
     ELISAs for RPL37
     CLIAs for RPL37
     Search LifeMap BioReagents cell lines for RPL37
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL37
     SwitchGear 3'UTR luciferase reporter plasmids for RPL37
     SwitchGear Promoter luciferase reporter plasmids for RPL37
     ThermoFisher Antibodies for RPL37
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL37
     inGenious Targeting Laboratory - Custom generated mouse model solutions for RPL37
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RPL37
    Customized:
     lentivirus for stable overexpression of RPL37
     lentivirus expression plasmids for stable overexpression of RPL37
     adenovirus for overexpression of RPL37
     LSBio Antibodies in human, mouse, rat for RPL37
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RPL37 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4