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RPL35 Gene

protein-coding   GIFtS: 64
GCID: GC09M127620

Ribosomal Protein L35

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein L351 2
60S Ribosomal Protein L351 2
L352
DBA55
RPL35A5

External Ids:    HGNC: 103441   Entrez Gene: 112242   Ensembl: ENSG000001369427   OMIM: 1804685   UniProtKB: P427663   

Export aliases for RPL35 gene to outside databases

Previous GC identifers: GC09M118734 GC09M119266 GC09M121073 GC09M122996 GC09M124699 GC09M126659 GC09M097233


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL35 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29P family
of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there
are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL35 Gene:
RPL35 (ribosomal protein L35) is a protein-coding gene. Diseases associated with RPL35 include pure red-cell aplasia, and diamond-blackfan anemia. GO annotations related to this gene include structural constituent of ribosome and mRNA binding.

Gene Wiki entry for RPL35 (60S ribosomal protein L35) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL35 gene promoter:
         Pax-2   Pax-2a   c-Ets-1   C/EBPalpha   GATA-2   PPAR-gamma1   Pax-2b   FOXO4   ZID   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL35 promoter sequence
   Search Chromatin IP Primers for RPL35

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL35


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.1   Ensembl cytogenetic band:  9q33.3   HGNC cytogenetic band: 9q34.1

RPL35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL35 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M127620:  view genomic region     (about GC identifiers)

Start:
127,620,158 bp from pter      End:
127,624,260 bp from pter
Size:
4,103 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RL35_HUMAN, P42766 (See protein sequence)
Recommended Name: 60S ribosomal protein L35  
Size: 123 amino acids; 14551 Da
Sequence caution: Sequence=CAI39638.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from and Proteopedia for RPL35:
3J3B (3D)    
Secondary accessions: A8K4V7 Q4VBY5 Q5JTN5 Q6IBC7 Q96QJ7 Q9BYF4

Explore the universe of human proteins at neXtProt for RPL35: NX_P42766

Explore proteomics data for RPL35 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys25, Lys66, Lys79
  • Modification sites at PhosphoSitePlus

  • See RPL35 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_009140.1  
    ENSEMBL proteins: 
     ENSP00000362671   ENSP00000437215   ENSP00000259469  
    Reactome Protein details: P42766

    RPL35 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    2 InterPro protein domains:
     IPR001854 Ribosomal_L29
     IPR018254 Ribosomal_L29_CS

    Graphical View of Domain Structure for InterPro Entry P42766

    ProtoNet protein and cluster: P42766

    1 Blocks protein domain: IPB001854 Ribosomal protein L29

    UniProtKB/Swiss-Prot: RL35_HUMAN, P42766
    Similarity: Belongs to the ribosomal protein L29P family


    RPL35 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL35:
    60S ribosomal protein L35,12kDa

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003729mRNA binding TAS2891103
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0044822poly(A) RNA binding IDA--
         
    RPL35 for ontologies           About GeneDecksing


    Phenotypes:
         8 GenomeRNAi human phenotypes for RPL35:
     Decreased TP53 protein express  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability of wild-ty 
     Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d  Synthetic lethal with Ras  Synthetic lethal with imatinib 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL35
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL35

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL35:
    hsa-mir-877-5p (MIRT037236), hsa-mir-1180-3p (MIRT035932), hsa-mir-1226-3p (MIRT036416)

    Block miRNA regulation of human, mouse, rat RPL35 using miScript Target Protectors
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL35


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus4
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005730nucleolus TAS2891103
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----

    RPL35 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL35 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL35
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL35
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPL35 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL35):
        Ribosome


    RPL35 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL35
    Interactions:

        Search GeneGlobe Interaction Network for RPL35

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL35 (P427661, 2, 3 ENSP000002594694) via UniProtKB, MINT, STRING, and/or I2D (see all 524)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL4P365782, 3, ENSP000003114304MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=7 STRING: ENSP00000311430
    RPL11P629132, 3, ENSP000003636764MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=6 STRING: ENSP00000363676
    RPL26P612542, 3, ENSP000002938424MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=6 STRING: ENSP00000293842
    RPS15AP622442, 3, ENSP000003186464MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=4 STRING: ENSP00000318646
    RPL27AP467762, 3, ENSP000003460154MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000346015
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL35 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL35 (RL35)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPL35 gene: 
    NM_007209.3  

    Unigene Cluster for RPL35:

    Ribosomal protein L35
    Hs.182825  [show with all ESTs]
    Unigene Representative Sequence: BU588374
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373570 ENST00000493018 ENST00000487431 ENST00000348462(uc004boy.1)
    ENST00000495728
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat RPL35
      QuantiFast Probe-based Assays in human, mouse, rat RPL35

    Additional mRNA sequence: 

    AK291072.1 BC000348.2 BC010919.1 BC071915.1 BC094828.1 CR456877.1 U12465.1 

    Selected DOTS entries (see all 52):

    DT.91981706  DT.95102648  DT.92002937  DT.102840122  DT.420330  DT.91888037  DT.91769340  DT.121373370 
    DT.121373391  DT.95102673  DT.100738353  DT.121155949  DT.102840123  DT.121063320  DT.91769349  DT.100700729 
    DT.121155958  DT.101986419  DT.121373365  DT.95102601  DT.95102674  DT.95110126  DT.95136098  DT.100738293 

    Selected AceView cDNA sequences (see all 1095):

    AW351780 AA336231 F28888 CN485168 BQ221991 BU855704 BF972706 AA352641 
    AA344056 CA434560 NM_007209 BQ682718 F27553 AA374409 BC071915 AI080006 
    BI223042 BM856507 CR622666 F36148 BM456519 BM015393 AI089666 AW328369 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for RPL35    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4
    SP1:                              
    SP2:                              


    ECgene alternative splicing isoforms for RPL35

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL35 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCCGCCGGC
    RPL35 Expression
    About this image


    RPL35 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Gonad
             Primary Oocyte Primary Follicle
    RPL35 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL35 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.182825
        Custom PCR Arrays for RPL35
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat RPL35
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL35

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL35 gene from Selected species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl351 , 5 ribosomal protein L351, 5 89.16(n)1
    98.37(a)1
      2 (24.42 cM)5
    664891  NM_025592.31  NP_079868.11 
     390015805 
    chicken
    (Gallus gallus)
    Aves RPL351 ribosomal protein L35 82.66(n)
    98.37(a)
      374133  NM_204273.1  NP_989604.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL356
    ribosomal protein L35
    95(a)
    1 ↔ 1
    GL344348.1(35529-37385)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.290672 Xenopus laevis transcribed sequence with strong similarity more 78.68(n)    48011882 
    zebrafish
    (Danio rerio)
    Actinopterygii rpl352 ribosomal protein L35 81.23(n)   192299  BC055640.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL351 Ribosomal protein L35 66.12(n)
    65.85(a)
      31483  NM_132015.2  NP_572243.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-351 , 3 60S ribosomal protein L353
    rpl-351
    67(a)3
    63.41(n)1
    67.48(a)1
      III(7926402-7927351)3
    1760971  NM_066301.51  NP_498702.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL35B(YDL136W)4
    RPL35B1
    Protein component of the large (60S) ribosomal subunit, more4
    RPL35B1
    54.44(n)1
    57.5(a)1
      4(217600-218367)4
    8514191, 4  NP_010090.11  NP_010145.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G026101 AT5G02610 63.96(n)
    64.23(a)
      831853  NM_001203280.1  NP_001190209.1 
    rice
    (Oryza sativa)
    Liliopsida Os.377682 Rice mRNA for ribosomal protein L35 (NH77 gene), partial more 78.3(n)    AK119701.1 


    ENSEMBL Gene Tree for RPL35 (if available)
    TreeFam Gene Tree for RPL35 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL35 gene
    1 SIMAP similar gene for RPL35 using alignment to 2 protein entries:     RL35_HUMAN (see all proteins):
    LOC154880

    RPL35 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPL35 (see all 10)
    PGOHUM00000248681 PGOHUM00000234466 PGOHUM00000245265 PGOHUM00000246354 PGOHUM00000235315


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL35 (see all 120)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1465509821,2
    --127620680(+) CACATA/GACAAC 1 -- int10--------
    rs1400153361,2
    --127620699(+) GGGCAC/TGCAGC 1 -- int10--------
    rs1437230611,2
    C--127620893(+) CCCCTA/GCCCAC 1 -- int10--------
    rs1468139291,2
    --127620899(+) CCCACA/GGCTGT 1 -- int10--------
    rs38187611,2
    C,F,A,H--127620945(-) GGCAGG/CAGTGG 1 -- int112Minor allele frequency- C:0.38EA NS NA WA 2158
    rs32159451,2
    C--127621191(-) CTGCC-/CACCTG 1 -- int12Minor allele frequency- C:0.25NA 4
    rs1892307551,2
    --127621207(+) TGCAGA/GAAGAT 1 -- int10--------
    rs1405708631,2
    --127621255(+) AGCAGC/GAAAGT 1 -- int10--------
    rs1817980501,2
    --127621297(+) GCATCA/GGCTGG 1 -- int10--------
    rs1160903561,2
    C,F--127621302(+) GGCTGG/AGCATT 1 -- int11Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for RPL35 (127620158 - 127624260 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RPL35:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831721CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL35
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL35

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 180468   
    OMIM disorders: 612528  
    5 diseases for RPL35:    
    About MalaCards
    pure red-cell aplasia    diamond-blackfan anemia    influenza    hiv-1
    malaria

    2 diseases from the University of Copenhagen DISEASES database for RPL35:
    Diamond-Blackfan anemia     Pure red-cell aplasia

    RPL35 for disorders           About GeneDecksing


    Export disorders for RPL35 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL35 gene, integrated from 10 sources (see all 53):
    (articles sorted by number of sources associating them with RPL35)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders. (PubMed id 11401437)1, 2, 3 Uechi T.... Kenmochi N. (Genomics 2001)
    2. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. (PubMed id 12962325)1, 2 Odintsova T.I....Karpova G.G. (J. Protein Chem. 2003)
    5. The role of expansion segment of human ribosomal protein L35 in nuclear entry, translation activity, and endoplasmic reticulum docking. (PubMed id 18523488)1, 9 Chen I.J....Lin A. (Biochem. Cell Biol. 2008)
    6. Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription. (PubMed id 24140708)1 Wu T....Zhang D.D. (amp 2014)
    7. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    10. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 11224 HGNC: 10344 AceView: RPL35 Ensembl:ENSG00000136942 euGenes: HUgn11224
    ECgene: RPL35 Kegg: 11224 H-InvDB: RPL35

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPL35 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RPL35 gene:
    Search GeneIP for patents involving RPL35

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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