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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL35 Gene

protein-coding   GIFtS: 60
GCID: GC09M127620

ribosomal protein L35
 Explore 4 diseases affiliated with
RPL35 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPL35    

Aliases
for RPL35 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein L351 2
L351 2
60S Ribosomal Protein L352
M5

External Ids:    HGNC: 103441   Entrez Gene: 112242   Ensembl: ENSG000001369427   OMIM: 6118415   UniProtKB: P427663   

Export aliases for RPL35 gene to outside databases

Previous GC identifers: GC09M118734 GC09M119266 GC09M121073 GC09M122996 GC09M124699 GC09M126659 GC09M097233


Summaries
for RPL35 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPL35:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29P family of
ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are
multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

Gene Wiki entry for RPL35 (60S ribosomal protein L35)


Genomic Views
for RPL35 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL35 gene promoter:
         Pax-2   Pax-2a   c-Ets-1   C/EBPalpha   GATA-2   PPAR-gamma1   Pax-2b   FOXO4   ZID   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPL35 promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL35

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL35


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.1   Ensembl cytogenetic band:  9q33.3   HGNC cytogenetic band: 9q34.1

RPL35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL35 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M127620:  view genomic region     (about GC identifiers)

Start:
 127,620,158 bp from pter      End:
 127,624,260 bp from pter
Size:
 4,103 bases      Orientation:
 minus strand

Proteins
for RPL35 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RL35_HUMAN, P42766 (See protein sequence)
Recommended Name: 60S ribosomal protein L35  
Size: 123 amino acids; 14551 Da
Sequence caution: Sequence=CAI39638.1; Type=Erroneous gene model prediction;
Secondary accessions: A8K4V7 Q4VBY5 Q5JTN5 Q6IBC7 Q96QJ7 Q9BYF4

Explore the universe of human proteins at neXtProt for RPL35: NX_P42766

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P42766

    • RPL35 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_009140.1  
    ENSEMBL proteins: 
     ENSP00000362671   ENSP00000437215   ENSP00000259469  
    Reactome Protein details: P42766
    Human Recombinant Protein Products: 
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    OriGene Purified Protein: RPL35
    OriGene Protein Over-expression Lysate: RPL35
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    Novus Biologicals RPL35 Protein
    Novus Biologicals RPL35 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPL35

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus TAS2891103
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325


    RPL35 for ontologies           About GeneDecksing



    RPL35 Antibody Products: 
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    Uscn ELISAs and CLIAs for RPL35

    Protein Domains /
    Families
    for RPL35 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPL35 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001854 Ribosomal_L29
     IPR018254 Ribosomal_L29_CS

    Graphical View of Domain Structure for InterPro Entry P42766

    ProtoNet protein and cluster: P42766

    1 Blocks protein family: IPB001854 Ribosomal protein L29

    UniProtKB/Swiss-Prot: RL35_HUMAN, P42766
    Similarity: Belongs to the ribosomal protein L29P family


    Function
    for RPL35 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for RPL35:
    60S ribosomal protein L35,12kDa

    miRNA
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    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL35 (see all 7)
    OriGene shRNA RFP: RPL35
    OriGene siRNA: RPL35
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL35

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RPL35

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL35 (see all 3)
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    Cell Line
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    Search LifeMap BioReagents cell lines for RPL35

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPL35

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003729mRNA binding TAS2891103
    GO:0003735structural constituent of ribosome NAS12962325


    RPL35 for ontologies           About GeneDecksing


    8 GenomeRNAi human phenotypes for RPL35:
     Decreased TP53 protein express  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability of wild-ty 
     Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d  Synthetic lethal with Ras  Synthetic lethal with imatinib 


    Pathways & Interactions
    for RPL35 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    3Disease
    		Disease1.00
    4Generic Transcription Pathway
    		Gene Expression0.46
    5Asparagine N-linked glycosylation
    		Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL35
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL35 
        Cytoplasmic Ribosomal Proteins

    5/28        Reactome Pathways for RPL35 (see all 28)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL35):
        Ribosome


    RPL35 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL35

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/443 Interacting proteins for RPL35 (P427661, 2, 3 ENSP000002594694) via UniProtKB, MINT, STRING, and/or I2D (see all 443)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL4P365782, 3, ENSP000003114304MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=7 STRING: ENSP00000311430
    RPL11P629132, 3, ENSP000003636764MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=6 STRING: ENSP00000363676
    RPL26P612542, 3, ENSP000002938424MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=6 STRING: ENSP00000293842
    RPS15AP622442, 3, ENSP000003186464MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=4 STRING: ENSP00000318646
    RPL27AP467762, 3, ENSP000003460154MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000346015
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPL35 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPL35 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPL35
    Search CenterWatch for drugs/clinical trials and news about RPL35 / RL35 

    Transcripts
    for RPL35 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPL35 gene: 
    NM_007209.3  

    Unigene Cluster for RPL35:

    Ribosomal protein L35
    Hs.182825  [show with all ESTs]
    Unigene Representative Sequence: BU588374
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373570 ENST00000493018 ENST00000487431 ENST00000348462(uc004boy.1)
    ENST00000495728

    miRNA
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    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL35 (see all 7)
    OriGene shRNA RFP: RPL35
    OriGene siRNA: RPL35
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPL35
    Clone
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    GenScript: all cDNA clones in your preferred vector: RPL35 (NM_000996)
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL35

    Additional cDNA sequence: 

    AK291072.1 BC000348.2 BC010919.1 BC071915.1 BC094828.1 CR456877.1 U12465.1 

    24/52 DOTS entries (see all 52):

    DT.91981706  DT.95102648  DT.92002937  DT.102840122  DT.420330  DT.91888037  DT.121373370  DT.121373391 
    DT.91769340  DT.95102673  DT.100738353  DT.121155949  DT.102840123  DT.91769349  DT.100700729  DT.121155958 
    DT.101986419  DT.121373365  DT.95102601  DT.95102674  DT.95110126  DT.95136098  DT.100738293  DT.121155936 

    24/1095 AceView cDNA sequences (see all 1095):

    AJ714580 AI292211 AI335638 BQ217930 BQ679605 AI720297 BF727171 BM747496 
    BF726189 BG942570 AA362087 BQ678676 AJ346663 AI240265 T34832 BQ887275 
    AA339256 BM928621 BM822969 T33974 BP430856 AA365568 AI080259 AA379184 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for RPL35    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4
    SP1:                              
    SP2:                              


    ECgene alternative splicing isoforms for RPL35

    Expression
    for RPL35 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL35 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGCCGCCGGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RPL35 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FolliclePrimary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RPL35 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL35

    SOURCE GeneReport for Unigene cluster: Hs.182825
        SABiosciences Custom PCR Arrays for RPL35
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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for RPL35

    Orthologs
    for RPL35 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL35 gene from 10/40 species (see all 40)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rpl351 , 5 ribosomal protein L351, 5 89.16(n)1
    98.37(a)1    		   2 (24.42 cM)5
    664891  NM_025592.31  NP_079868.11 
     390015805 
    chicken
    (Gallus gallus)    		 Aves RPL351 ribosomal protein L35 82.66(n)
    98.37(a)    		   374133  NM_204273.1  NP_989604.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RPL356
    		 --
    		 95(a)
    		 1 ↔ 1
    		 GL344348.1(35529-37383)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.290672 Xenopus laevis transcribed sequence with strong similarity more 78.68(n)    48011882 
    zebrafish
    (Danio rerio)    		 Actinopterygii rpl352 ribosomal protein L35 81.23(n)   192299  BC055640.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpL351 Ribosomal protein L35 66.12(n)
    65.85(a)    		   31483  NM_132015.2  NP_572243.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea rpl-351 , 3 60S ribosomal protein L353
    Protein RPL-351    		 67(a)3
    63.41(n)1
    67.48(a)1    		   III(7926402-7927351)3
    1760971  NM_066301.41  NP_498702.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes RPL35B(YDL136W)4
    RPL35B1    		 Protein component of the large (60S) ribosomal subunit, more4
    Rpl35bp1    		 54.17(n)1
    57.5(a)1    		   4(217600-218367)4
    8514191, 4  NP_010090.11  NP_010145.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G026101 60S ribosomal protein L35-4 64.21(n)
    64.75(a)    		   831853  NM_001203280.1  NP_001190209.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.377682 Rice mRNA for ribosomal protein L35 (NH77 gene), partial more 78.3(n)    AK119701.1 


    ENSEMBL Gene Tree for RPL35 (if available)
    TreeFam Gene Tree for RPL35 (if available) 

    Paralogs
    for RPL35 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL35 gene
    1 SIMAP similar gene for RPL35 using alignment to 3 protein entries:     RL35_HUMAN (see all proteins):
    LOC154880

    RPL35 for paralogs           About GeneDecksing


    5/10 Pseudogenes.org Pseudogenes for RPL35 (see all 10)
    PGOHUM00000248681 PGOHUM00000234466 PGOHUM00000245265 PGOHUM00000246354 PGOHUM00000235315


    Genomic Variants
    for RPL35 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/122 NCBI SNPs in RPL35 are shown (see all 122)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs735910451,2
    		C,--127619703(+) ACGGCG/ACTGTG 2 -- int1 ds50011Minor allele frequency- A:0.50WA 2
    rs1426607901,2
    		--127619726(+) CTGTGC/GACAGC 2 -- int1 ds50010--------
    rs2021303921,2
    		--127619745(+) AGGCAC/GGACTT 2 -- ds5001 int10--------
    rs9449521,2
    		C,F,H,--127619922(+) CACCTC/TAGATG 2 -- ut31 ds500137Minor allele frequency- T:0.11MN NS EA NA WA CSA EU 5799
    rs1929194341,2
    		--127619958(+) GTGGCA/GCACAG 2 -- ut31 ds50010--------
    rs1846905661,2
    		--127619979(+) TCTCCC/TCACAG 2 -- ut31 ds50010--------
    rs8766631,2
    		C,F,O,A,H,--127620141(-) GCACTT/CCCACT 2 -- ut31 ds500126Minor allele frequency- C:0.31MN NS EA NA WA 4326
    rs2005374521,2
    		--127620157(+) AACAAA/CGCAGT 2 -- ds5001 ut310--------
    rs2017910051,2
    		--127620188(+) TGACAA/CTGCGC 2 -- ut31 ds50010--------
    rs1129711211,2
    		C,F--127620203(+) CAGGCC/TTTGAC 3 K ds5001 syn12Minor allele frequency- T:0.00CSA NA 4486

    HapMap Linkage Disequilibrium report for RPL35 (127620158 - 127624260 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RPL35: --

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    Disorders / Diseases
    for RPL35 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPL35 for disorders           About GeneDecksing

    OMIM gene information: 611841    OMIM disorders: --

    4 diseases for RPL35:    About MalaCards
    pure red-cell aplasia    diamond-blackfan anemia    anemia    malaria

    2 diseases from the University of Copenhagen DISEASES database for RPL35:
    Diamond-Blackfan anemia     Pure red-cell aplasia

    Export disorders for RPL35 gene to outside databases

    Publications
    for RPL35 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL35 gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with RPL35)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders. (PubMed id 11401437)1, 2, 3 Uechi T.... Kenmochi N. (2001)
    2. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. (PubMed id 12962325)1, 2 Odintsova T.I....Karpova G.G. (2003)
    5. The role of expansion segment of human ribosomal protein L35 in nuclear entry, translation activity, and endoplasmic reticulum docking. (PubMed id 18523488)1, 9 Chen I.J....Lin A. (2008)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. A catalogue of putative HIV-1 protease host cell subst rates. (PubMed id 22944692)1 Impens F....Gevaert K. (2012)
    10. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)

    External Searches for RPL35 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    OMIM
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    Genome Databases showing RPL35 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11224 HGNC: 10344 AceView: RPL35 Ensembl:ENSG00000136942 euGenes: HUgn11224
    ECgene: RPL35 Kegg: 11224 H-InvDB: RPL35

    Other Databases showing RPL35 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPL35 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL35 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPL35 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPL35 gene:
    Search GeneIP for patents involving RPL35

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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