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Aliases for RPL32 Gene

Aliases for RPL32 Gene

  • Ribosomal Protein L32 2 3
  • 60S Ribosomal Protein L32 3
  • PP9932 3
  • L32 3
  • M 6

External Ids for RPL32 Gene

Previous GeneCards Identifiers for RPL32 Gene

  • GC03M012806
  • GC03M012869
  • GC03M012852
  • GC03M012853
  • GC03M012810
  • GC03M012876
  • GC03M012877

Summaries for RPL32 Gene

Entrez Gene Summary for RPL32 Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for RPL32 Gene

RPL32 (Ribosomal Protein L32) is a Protein Coding gene. Among its related pathways are Disease and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for RPL32 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL32 Gene

Genomics for RPL32 Gene

Regulatory Elements for RPL32 Gene

Transcription factor binding sites by QIAGEN in the RPL32 gene promoter:

Genomic Location for RPL32 Gene

Start:
12,834,485 bp from pter
End:
12,841,588 bp from pter
Size:
7,104 bases
Orientation:
Minus strand

Genomic View for RPL32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPL32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL32 Gene

Proteins for RPL32 Gene

  • Protein details for RPL32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P62910-RL32_HUMAN
    Recommended name:
    60S ribosomal protein L32
    Protein Accession:
    P62910
    Secondary Accessions:
    • B2R4Q3
    • P02433

    Protein attributes for RPL32 Gene

    Size:
    135 amino acids
    Molecular mass:
    15860 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPL32 Gene

neXtProt entry for RPL32 Gene

Proteomics data for RPL32 Gene at MOPED

Post-translational modifications for RPL32 Gene

  • Ubiquitination at Lys50
  • Modification sites at PhosphoSitePlus

Other Protein References for RPL32 Gene

No data available for DME Specific Peptides for RPL32 Gene

Domains for RPL32 Gene

Gene Families for RPL32 Gene

HGNC:
  • RPL :L ribosomal proteins

Protein Domains for RPL32 Gene

Suggested Antigen Peptide Sequences for RPL32 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P62910

UniProtKB/Swiss-Prot:

RL32_HUMAN :
  • P62910
Family:
  • Belongs to the ribosomal protein L32e family.
genes like me logo Genes that share domains with RPL32: view

Function for RPL32 Gene

Molecular function for RPL32 Gene

GENATLAS Biochemistry: 60S ribosomal protein L32,15kDa

Gene Ontology (GO) - Molecular Function for RPL32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome NAS 12962325
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RPL32: view
genes like me logo Genes that share phenotypes with RPL32: view

miRNA for RPL32 Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RPL32 Gene

Localization for RPL32 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RPL32 Gene COMPARTMENTS Subcellular localization image for RPL32 gene
Compartment Confidence
cytosol 5
chloroplast 3
mitochondrion 2
nucleus 2

Gene Ontology (GO) - Cellular Components for RPL32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005737 cytoplasm IDA --
GO:0005813 centrosome IDA --
GO:0005829 cytosol TAS --
GO:0005840 ribosome --
genes like me logo Genes that share ontologies with RPL32: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPL32 Gene

Pathways for RPL32 Gene

genes like me logo Genes that share pathways with RPL32: view

Pathways by source for RPL32 Gene

1 KEGG pathway for RPL32 Gene
1 GeneGo (Thomson Reuters) pathway for RPL32 Gene

Gene Ontology (GO) - Biological Process for RPL32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0006412 translation TAS --
GO:0006413 translational initiation TAS --
GO:0006414 translational elongation TAS --
GO:0006415 translational termination TAS --
genes like me logo Genes that share ontologies with RPL32: view

Compounds for RPL32 Gene

(1) Novoseek inferred chemical compound relationships for RPL32 Gene

Compound -log(P) Hits PubMed IDs
glyceraldehyde 3-phosphate 60.9 2
genes like me logo Genes that share compounds with RPL32: view

Transcripts for RPL32 Gene

Unigene Clusters for RPL32 Gene

Ribosomal protein L32:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RPL32 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
SP1:
SP2: -

Relevant External Links for RPL32 Gene

GeneLoc Exon Structure for
RPL32
ECgene alternative splicing isoforms for
RPL32

Expression for RPL32 Gene

mRNA expression in normal human tissues for RPL32 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RPL32 Gene

SOURCE GeneReport for Unigene cluster for RPL32 Gene Hs.265174

genes like me logo Genes that share expressions with RPL32: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPL32 Gene

Orthologs for RPL32 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPL32 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC450727 35
  • 100 (n)
  • 100 (a)
RPL32 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RPL32 35
  • 92.1 (n)
  • 99.26 (a)
RPL32 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 97 (a)
OneToMany
RPL32 35
  • 94.07 (n)
  • 100 (a)
mouse
(Mus musculus)
Mammalia Gm21893 36
  • 45 (a)
OneToMany
Gm6251 35
  • 88.47 (n)
  • 95.49 (a)
Rpl32 16
platypus
(Ornithorhynchus anatinus)
Mammalia RPL32 36
  • 93 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC680959 35
  • 87.16 (n)
  • 91.11 (a)
chicken
(Gallus gallus)
Aves RPL32 35
  • 83.7 (n)
  • 94.81 (a)
RPL32 36
  • 95 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RPL32 36
  • 95 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.26095 35
tropical clawed frog
(Silurana tropicalis)
Amphibia rpl32 35
  • 79.75 (n)
  • 93.33 (a)
zebrafish
(Danio rerio)
Actinopterygii rpl32 35
  • 80 (n)
  • 91.85 (a)
rpl32 36
  • 92 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002122 35
  • 69.42 (n)
  • 79.7 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpL32 35
  • 69.92 (n)
  • 76.69 (a)
RpL32 36
  • 69 (a)
OneToOne
RpL32 37
  • 77 (a)
worm
(Caenorhabditis elegans)
Secernentea rpl-32 35
  • 59.9 (n)
  • 59.37 (a)
rpl-32 36
  • 57 (a)
OneToOne
rpl-32 37
  • 60 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AGL281C 35
  • 62.56 (n)
  • 63.85 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL32 35
  • 59.69 (n)
  • 61.24 (a)
RPL32 36
  • 62 (a)
OneToOne
RPL32 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E06843g 35
  • 60.7 (n)
  • 62.6 (a)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.8117 35
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G18100 35
  • 64.62 (n)
  • 66.92 (a)
rice
(Oryza sativa)
Liliopsida Os.12339 35
Os08g0524600 35
  • 67.44 (n)
  • 68.46 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpl3202 35
  • 59.56 (n)
  • 59.02 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 70 (a)
OneToOne
Species with no ortholog for RPL32:
  • Actinobacteria (Mycobacterium tuberculosis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPL32 Gene

ENSEMBL:
Gene Tree for RPL32 (if available)
TreeFam:
Gene Tree for RPL32 (if available)

Paralogs for RPL32 Gene

genes like me logo Genes that share paralogs with RPL32: view

No data available for Paralogs for RPL32 Gene

Variants for RPL32 Gene

Sequence variations from dbSNP and Humsavar for RPL32 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs6497 -- 12,836,205(-) GAGAT(A/C/G/T)GCTCA synonymous-codon, reference, missense
rs12358 -- 12,836,088(-) GGCAG(C/T)CATGT utr-variant-3-prime
rs748199 -- 12,835,406(-) TTGGA(A/G)ACGGG utr-variant-3-prime
rs1064728 -- 12,836,117(-) CCAGG(C/G)TGCGC reference, missense
rs2290312 -- 12,839,319(-) TTCAG(G/T)GATCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RPL32 Gene

Variant ID Type Subtype PubMed ID
dgv810e201 CNV Deletion 23290073
dgv850e199 CNV Deletion 23128226
nsv7351 OTHER Inversion 18451855
esv2751977 CNV Gain 17911159
nsv460435 CNV Loss 19166990
nsv821995 CNV Gain 20364138

Relevant External Links for RPL32 Gene

HapMap Linkage Disequilibrium report
RPL32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPL32 Gene

Disorders for RPL32 Gene

No disorders were found for RPL32 Gene.

No data available for UniProtKB/Swiss-Prot for RPL32 Gene

Publications for RPL32 Gene

  1. A processed pseudogene in an intron of the HLA-DP beta 1 chain gene is a member of the ribosomal protein L32 gene family. (PMID: 3866218) Young J.A.T. … Trowsdale J. (Nucleic Acids Res. 1985) 3 4
  2. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PMID: 11875025) Yoshihama M. … Kenmochi N. (Genome Res. 2002) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  5. Assignment of the L32 ribosomal protein gene (RPL32) to human chromosome 3q13.3-->q21 by in situ hybridization. (PMID: 9284913) Vorobieva N.V. … Graphodatsky A.S. (Cytogenet. Cell Genet. 1997) 2 3

Products for RPL32 Gene

Sources for RPL32 Gene

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