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RPL31 Gene

protein-coding   GIFtS: 63
GCID: GC02P101618

Ribosomal Protein L31

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein L311 2
60S Ribosomal Protein L312
L312
MMRPS325
MRPL425

External Ids:    HGNC: 103341   Entrez Gene: 61602   Ensembl: ENSG000000710827   OMIM: 6118475   UniProtKB: P628993   

Export aliases for RPL31 gene to outside databases

Previous GC identifers: GC02P099482 GC02P100071 GC02P101224 GC02P101240 GC02P101077 GC02P100985 GC02P095382


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL31 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family
of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial
adenomatous polyps compared to matched normal tissues have been observed. As is typical for genes encoding
ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. (provided by
RefSeq, Jul 2008)

GeneCards Summary for RPL31 Gene:
RPL31 (ribosomal protein L31) is a protein-coding gene. Diseases associated with RPL31 include chancroid, and nasopharynx carcinoma. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL31 (60S ribosomal protein L31) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL31 gene promoter:
         MEF-2   POU3F2   AREB6   MEF-2A   c-Rel   SRY   CBF-A   aMEF-2   Hlf   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL31 promoter sequence
   Search Chromatin IP Primers for RPL31

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

RPL31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL31 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P101618:  view genomic region     (about GC identifiers)

Start:
101,618,177 bp from pter      End:
101,640,494 bp from pter
Size:
22,318 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RL31_HUMAN, P62899 (See protein sequence)
Recommended Name: 60S ribosomal protein L31  
Size: 125 amino acids; 14463 Da
1 PDB 3D structure from and Proteopedia for RPL31:
3J3B (3D)    
Secondary accessions: B7Z4K2 D3DVJ4 P12947 Q53SQ5 Q6IRZ0 Q6LBJ6
Alternative splicing: 3 isoforms:  P62899-1   P62899-2   P62899-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPL31: NX_P62899

Explore proteomics data for RPL31 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys39, Lys55, Lys70, Lys75, Lys115
  • Modification sites at PhosphoSitePlus

  • See RPL31 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_000984.1  NP_001092047.1  NP_001093163.1  

    ENSEMBL proteins: 
     ENSP00000264258   ENSP00000387120   ENSP00000386717   ENSP00000387163   ENSP00000386681  
     ENSP00000386271   ENSP00000386737   ENSP00000402450   ENSP00000412976   ENSP00000387112  
     ENSP00000408172  
    Reactome Protein details: P62899

    RPL31 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RPL31

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    Cloud-Clone Corp. CLIAs for RPL31


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    3 InterPro protein domains:
     IPR020052 Ribosomal_L31e_CS
     IPR000054 Ribosomal_L31e
     IPR023621 Ribosomal_L31e_dom

    Graphical View of Domain Structure for InterPro Entry P62899

    ProtoNet protein and cluster: P62899

    UniProtKB/Swiss-Prot: RL31_HUMAN, P62899
    Similarity: Belongs to the ribosomal protein L31e family


    RPL31 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL31:
    60S ribosomal protein L31,14kDa

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS2780320
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0044822poly(A) RNA binding IDA--
         
    RPL31 for ontologies           About GeneDecksing


    Phenotypes:
         8 GenomeRNAi human phenotypes for RPL31:
     Decreased cell number, increas  Decreased number of cells in m  Decreased viability  Decreased viability of wild-ty 
     Increased number of mitotic ce  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d  S arrest 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL31
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    miRNA
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    miRTarBase miRNAs that target RPL31:
    hsa-mir-100-5p (MIRT048580), hsa-mir-18a-3p (MIRT040775), hsa-mir-20a-5p (MIRT050516), hsa-mir-16-5p (MIRT032013), hsa-let-7d-5p (MIRT051714), hsa-mir-615-3p (MIRT040307), hsa-mir-324-3p (MIRT042935)

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL31


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325
    GO:0070062extracellular vesicular exosome IDA--

    RPL31 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL31 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL31
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL31
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL31 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL31):
        Ribosome


    RPL31 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL31
    Interactions:

        Search GeneGlobe Interaction Network for RPL31

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL31 (P628991, 2, 3 ENSP000003867174) via UniProtKB, MINT, STRING, and/or I2D (see all 1169)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LYARQ9NX581, 2, 3EBI-1053664,EBI-713507 MINT-6488590 I2D: score=2 
    ENSG00000096150P622692, 3MINT-7945693 I2D: score=1 
    ENSG00000223367P622692, 3MINT-7945693 I2D: score=1 
    ENSG00000226225P622692, 3MINT-7945693 I2D: score=1 
    ENSG00000235650P622692, 3MINT-7945693 I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL31 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL31 (RL31)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPL31 gene (3 alternative transcripts): 
    NM_000993.4  NM_001098577.2  NM_001099693.1  

    Unigene Cluster for RPL31:

    Ribosomal protein L31
    Hs.469473  [show with all ESTs]
    Unigene Representative Sequence: AK093543
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264258(uc002taq.4) ENST00000409000 ENST00000409028(uc010fiu.1)
    ENST00000409320(uc002tar.4) ENST00000409733 ENST00000409650 ENST00000409038(uc010yvu.1 uc010yvv.1)
    ENST00000419276 ENST00000456292 ENST00000409711 ENST00000441435
    miRNA
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    GenScript: all cDNA clones in your preferred vector (see all 3): RPL31 (NM_000993)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL31
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL31
    Primer
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    OriGene qPCR primer pairs and template standards for RPL31
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL31
      QuantiTect SYBR Green Assays in human, mouse, rat RPL31
      QuantiFast Probe-based Assays in human, mouse, rat RPL31

    Additional mRNA sequence: 

    AB019567.1 AK093543.1 AK297167.1 AK297247.1 AK297483.1 AK311775.1 BC001663.2 BC017343.2 
    BC070210.1 BC070373.1 X15940.1 X69181.1 

    Selected DOTS entries (see all 98):

    DT.121029607  DT.91804820  DT.100718815  DT.120749337  DT.102843741  DT.100718805  DT.95277739  DT.86997893 
    DT.100890286  DT.75162205  DT.100718829  DT.100890287  DT.92000061  DT.95182293  DT.100718807  DT.91738896 
    DT.92042127  DT.87004867  DT.91999249  DT.100045789  DT.100718812  DT.40116273  DT.100718820  DT.121029649 

    Selected AceView cDNA sequences (see all 2190):

    AA716707 AI718211 BF796409 AA659894 BE378854 AA687427 BM264583 AW167794 
    BE393380 AA301780 BQ637108 BF127700 AA782171 N22305 AA164616 BP380754 
    AI707831 AL037873 BE742410 AA955030 BU688821 AA156197 AA025775 BM834991 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RPL31    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4
    SP1:              -           -     -         
    SP2:                                          
    SP3:              -                           


    ECgene alternative splicing isoforms for RPL31

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGAGATGG
    RPL31 Expression
    About this image


    RPL31 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 13 entries
             Cerebral Cortex
             Septum   
     
     Thyroid (Endocrine System)
     
     Umbilical Cord (Extraembryonic Tissues)
    RPL31 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL31 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.469473
        Custom PCR Arrays for RPL31
    Primer
    Products:
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    QuantiFast Probe-based Assays in human, mouse, rat RPL31
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL31 gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl311 , 5 ribosomal protein L311, 5 90.93(n)1
    100(a)1
      1 (18.30 cM)5
    1146411  NM_053257.31  NP_444487.11 
     393678515 
    chicken
    (Gallus gallus)
    Aves RPL311 ribosomal protein L31 85.07(n)
    98.4(a)
      418710  NM_001277755.1  NP_001264684.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL316
    ribosomal protein L31
    94(a)
    1 ↔ 1
    GL343542.1(229159-238968)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rpl311 ribosomal protein L31 81.07(n)
    95.2(a)
      448698  NM_001005118.2  NP_001005118.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rpl311 ribosomal protein L31 79.76(n)
    92.86(a)
      677758  NM_001040052.2  NP_001035141.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL313 protein biosynthesis structural
    constituent of more
    74(a)   45F5   --
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-311 , 3 Ribosomal protein L31e3
    rpl-311
    71(a)3
    66.97(n)1
    71.82(a)1
      I(13661041-13661734)3
    1732351  NM_060990.51  NP_493391.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL31A(YDL075W)4
    RPL31A1
    Protein component of the large (60S) ribosomal subunit, more4
    RPL31A1
    58.56(n)1
    58.56(a)1
      4(322226-322988)4
    8514841, 4  NP_010208.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G262301 AT4G26230 57.41(n)
    58.33(a)
      828729  NM_118756.4  NP_194353.1 
    rice
    (Oryza sativa)
    Liliopsida AK105284.12   -- 77.6(n)    AK105284.1 


    ENSEMBL Gene Tree for RPL31 (if available)
    TreeFam Gene Tree for RPL31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL31 gene
    1 SIMAP similar gene for RPL31 using alignment to 6 protein entries:     RL31_HUMAN (see all proteins):
    LOC402248

    RPL31 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPL31 (see all 68)
    PGOHUM00000251246 PGOHUM00000251262 PGOHUM00000242806 PGOHUM00000242915 PGOHUM00000239302


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL31 (see all 145)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1837583121,2
    --101616701(+) TTACTA/GCCTCT 3 -- us2k10--------
    rs1891321511,2
    --101616852(+) TGAAAG/TGCCTG 3 -- us2k10--------
    rs102094591,2
    C,F,H--101616887(+) ATGAGG/AAAGAG 3 -- us2k1 trp310Minor allele frequency- A:0.05NS EA NA CSA WA 1206
    rs102014161,2
    C,F,A,H--101617245(+) TGGGCA/GACAGA 3 -- us2k16Minor allele frequency- G:0.30NA WA NS 156
    rs1911382361,2
    --101617249(+) CAACAC/GAGCGA 3 -- us2k10--------
    rs1149653481,2
    C,F--101617434(+) AGAAAT/ACTACT 3 -- us2k12Minor allele frequency- A:0.02NA NS 270
    rs101896971,2
    C,F,A,H--101617493(+) GGCTTC/GCTTGT 3 -- us2k122Minor allele frequency- G:0.24NS EA NA WA CSA 2494
    rs1450322991,2
    --101617602(+) CTGTTC/GCAGCC 3 -- us2k10--------
    rs177192151,2
    C,F,H--101617606(+) TCCAGC/TCCTGA 3 -- us2k18Minor allele frequency- T:0.01NA NS EA 676
    rs1836429081,2
    --101617614(+) TGAAAC/TTGCCT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL31 (101618177 - 101640494 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RPL31:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv34123CNV Loss18971310
    nsv834316CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL31
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611847    OMIM disorders: --

    9 diseases for RPL31:    
    About MalaCards
    chancroid    nasopharynx carcinoma    treacher collins syndrome    influenza
    ataxia    rheumatoid arthritis    arthritis    thyroiditis
    cerebritis

    1 disease from the University of Copenhagen DISEASES database for RPL31:
    Chancroid

    RPL31 for disorders           About GeneDecksing


    Export disorders for RPL31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL31 gene, integrated from 10 sources (see all 61):
    (articles sorted by number of sources associating them with RPL31)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PubMed id 11875025)1, 2, 3 Yoshihama M.... Kenmochi N. (Genome Res. 2002)
    2. cDNA sequence of human ribosomal protein L31. (PubMed id 2780320)1, 2, 3 Nobori T.... Carson D.A. (Nucleic Acids Res. 1989)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Identification of a human ribosomal protein mRNA with increased expression in colorectal tumours. (PubMed id 2597680)1, 2 Chester K.A....Malcolm A.D.B. (Biochim. Biophys. Acta 1989)
    8. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. (PubMed id 23184937)1 Xie Y....Cong F. (J. Biol. Chem. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 6160 HGNC: 10334 AceView: RPL31 Ensembl:ENSG00000071082 euGenes: HUgn6160
    ECgene: RPL31 Kegg: 6160 H-InvDB: RPL31

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPL31 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RPL31 gene:
    Search GeneIP for patents involving RPL31

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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