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Aliases for RPL30 Gene

Aliases for RPL30 Gene

  • Ribosomal Protein L30 2 3
  • L30 3

External Ids for RPL30 Gene

Previous GeneCards Identifiers for RPL30 Gene

  • GC08M098062
  • GC08M099127
  • GC08M098713
  • GC08M099010
  • GC08M099123
  • GC08M094257
  • GC08M099037

Summaries for RPL30 Gene

Entrez Gene Summary for RPL30 Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30E family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U72 small nucleolar RNA gene, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

GeneCards Summary for RPL30 Gene

RPL30 (Ribosomal Protein L30) is a Protein Coding gene. Among its related pathways are Infectious disease and Transport to the Golgi and subsequent modification. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.

Gene Wiki entry for RPL30 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL30 Gene

Genomics for RPL30 Gene

Regulatory Elements for RPL30 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RPL30 Gene

98,024,851 bp from pter
98,046,469 bp from pter
21,619 bases
Minus strand

Genomic View for RPL30 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPL30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL30 Gene

Proteins for RPL30 Gene

  • Protein details for RPL30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    60S ribosomal protein L30
    Protein Accession:
    Secondary Accessions:
    • B2R591
    • P04645
    • Q502Z6

    Protein attributes for RPL30 Gene

    115 amino acids
    Molecular mass:
    12784 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPL30 Gene

neXtProt entry for RPL30 Gene

Proteomics data for RPL30 Gene at MOPED

Post-translational modifications for RPL30 Gene

  • Ubiquitination at Lys 32, Lys 44, Lys 57, Lys 68, and Lys 87
  • Modification sites at PhosphoSitePlus

Other Protein References for RPL30 Gene

Antibody Products

No data available for DME Specific Peptides for RPL30 Gene

Domains & Families for RPL30 Gene

Gene Families for RPL30 Gene

Suggested Antigen Peptide Sequences for RPL30 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ribosomal protein L30e family.
  • Belongs to the ribosomal protein L30e family.
genes like me logo Genes that share domains with RPL30: view

Function for RPL30 Gene

Molecular function for RPL30 Gene

GENATLAS Biochemistry:
60S ribosomal protein L30,12kDa,likely same as D8S1364E

Gene Ontology (GO) - Molecular Function for RPL30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding TAS 1577483
GO:0003735 structural constituent of ribosome TAS 1577483
GO:0005515 protein binding IPI 22720776
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RPL30: view
genes like me logo Genes that share phenotypes with RPL30: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RPL30

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RPL30 Gene

Localization for RPL30 Gene

Subcellular locations from

Jensen Localization Image for RPL30 Gene COMPARTMENTS Subcellular localization image for RPL30 gene
Compartment Confidence
cytosol 5
extracellular 5
nucleus 5

Gene Ontology (GO) - Cellular Components for RPL30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 22720776
GO:0005737 cytoplasm IDA --
GO:0005829 cytosol TAS --
GO:0005840 ribosome --
GO:0005925 focal adhesion IDA 21423176
genes like me logo Genes that share ontologies with RPL30: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPL30 Gene

Pathways & Interactions for RPL30 Gene

genes like me logo Genes that share pathways with RPL30: view

Pathways by source for RPL30 Gene

1 KEGG pathway for RPL30 Gene
1 GeneGo (Thomson Reuters) pathway for RPL30 Gene

Gene Ontology (GO) - Biological Process for RPL30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0002181 cytoplasmic translation IBA --
GO:0006412 translation TAS 1577483
GO:0006413 translational initiation TAS --
GO:0006414 translational elongation TAS --
genes like me logo Genes that share ontologies with RPL30: view

No data available for SIGNOR curated interactions for RPL30 Gene

Drugs & Compounds for RPL30 Gene

No Compound Related Data Available

Transcripts for RPL30 Gene

mRNA/cDNA for RPL30 Gene

Unigene Clusters for RPL30 Gene

Ribosomal protein L30:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RPL30

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RPL30 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d
SP1: - - - - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - -
SP5: - - - - -
SP6: - - -
SP7: - -
SP8: -
SP9: - - -

Relevant External Links for RPL30 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RPL30 Gene

mRNA expression in normal human tissues for RPL30 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for RPL30 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (7.4) and Pancreas (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RPL30 Gene

SOURCE GeneReport for Unigene cluster for RPL30 Gene Hs.400295

genes like me logo Genes that share expression patterns with RPL30: view

Protein tissue co-expression partners for RPL30 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPL30 Gene

Orthologs for RPL30 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPL30 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RPL30 35
  • 94.2 (n)
  • 100 (a)
RPL30 36
  • 97 (a)
(Canis familiaris)
Mammalia RPL30 35
  • 93.04 (n)
  • 99.13 (a)
RPL30 36
  • 85 (a)
(Mus musculus)
Mammalia Rpl30 35
  • 94.2 (n)
  • 100 (a)
Rpl30 16
Rpl30 36
  • 100 (a)
(Pan troglodytes)
Mammalia RPL30 35
  • 99.42 (n)
  • 100 (a)
RPL30 36
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC100362027 35
  • 93.04 (n)
  • 100 (a)
(Monodelphis domestica)
Mammalia RPL30 36
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia RPL30 36
  • 88 (a)
(Gallus gallus)
Aves RPL30 35
  • 85.8 (n)
  • 99.13 (a)
RPL30 36
  • 85 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 99 (a)
-- 36
  • 96 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC89963 35
  • 85.59 (n)
  • 100 (a)
Str.750 35
(Danio rerio)
Actinopterygii rpl30 35
  • 81.16 (n)
  • 96.52 (a)
wufa93d05 35
rpl30 36
  • 95 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpL30 37
  • 81 (a)
RpL30 35
  • 70.37 (n)
  • 81.48 (a)
RpL30 36
  • 80 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003816 35
  • 72.12 (n)
  • 83.64 (a)
(Caenorhabditis elegans)
Secernentea rpl-30 37
  • 72 (a)
rpl-30 35
  • 63.36 (n)
  • 72.07 (a)
rpl-30 36
  • 70 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR478W 35
  • 61.67 (n)
  • 60 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E10847g 35
  • 60 (n)
  • 61 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL30 35
  • 62 (n)
  • 61 (a)
RPL30 36
  • 58 (a)
RPL30 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G36240 35
  • 66.67 (n)
  • 72.48 (a)
(Glycine max)
eudicotyledons Gma.15471 35
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.7503 35
(Oryza sativa)
Liliopsida Os01g0276000 35
  • 69.37 (n)
  • 73.87 (a)
(Triticum aestivum)
Liliopsida Ta.3371 35
(Zea mays)
Liliopsida Zm.12150 35
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13337 35
bread mold
(Neurospora crassa)
Ascomycetes NCU08963 35
  • 60.58 (n)
  • 61.54 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpl3002 35
  • 62.09 (n)
  • 69.61 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 79 (a)
Species with no ortholog for RPL30:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for RPL30 Gene

Gene Tree for RPL30 (if available)
Gene Tree for RPL30 (if available)

Paralogs for RPL30 Gene

genes like me logo Genes that share paralogs with RPL30: view

No data available for Paralogs for RPL30 Gene

Variants for RPL30 Gene

Sequence variations from dbSNP and Humsavar for RPL30 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs812 -- 98,045,298(-) GATGT(C/G/T)TTGGC intron-variant
rs816 -- 98,045,276(-) GATGT(C/G/T)AGCCC intron-variant
rs6571 -- 98,041,790(+) TTGTA(A/G)GTGAA utr-variant-3-prime
rs9879 -- 98,042,663(-) GCACA(C/T)TGGCT reference, synonymous-codon
rs10591 -- 98,045,379(-) GCTCC(C/T)AAGGC utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for RPL30 Gene

Variant ID Type Subtype PubMed ID
esv2674440 CNV Deletion 23128226

Variation tolerance for RPL30 Gene

Residual Variation Intolerance Score: 49.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RPL30 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPL30 Gene

Disorders for RPL30 Gene

Relevant External Links for RPL30

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with RPL30: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPL30 Gene

Publications for RPL30 Gene

  1. [Function of TTG1A in hepatic stellate cells]. (PMID: 20038335) Xiao L. … Li Y. (Zhonghua Gan Zang Bing Za Zhi 2009) 23 67
  2. Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements. (PMID: 18691435) Jiang W. … Yang B. (BMC Syst Biol 2008) 23 67
  3. Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. (PMID: 16968546) De Bortoli M. … Kim J.Y. (BMC Cancer 2006) 23 67
  4. Identification of the antigens predominantly reacted with serum from patients with hepatocellular carcinoma. (PMID: 12733146) Uemura M. … Shiratori Y. (Cancer 2003) 23 67
  5. Integrated genetic and physical map of the 1q31-->q32.1 region, encompassing the RP12 locus, the F13B and HF1 genes, and the EEF1AL11 and RPL30 pseudogenes. (PMID: 10343093) van Soest S. … Bergen A.A. (Cytogenet. Cell Genet. 1999) 23 67

Products for RPL30 Gene

Sources for RPL30 Gene

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