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Aliases for RPL30 Gene

Aliases for RPL30 Gene

  • Ribosomal Protein L30 2 3 5
  • 60S Ribosomal Protein L30 3
  • L30 3

External Ids for RPL30 Gene

Previous GeneCards Identifiers for RPL30 Gene

  • GC08M098062
  • GC08M099127
  • GC08M098713
  • GC08M099010
  • GC08M099123
  • GC08M094257
  • GC08M099037

Summaries for RPL30 Gene

Entrez Gene Summary for RPL30 Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30E family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U72 small nucleolar RNA gene, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

GeneCards Summary for RPL30 Gene

RPL30 (Ribosomal Protein L30) is a Protein Coding gene. Among its related pathways are Viral mRNA Translation and Transport to the Golgi and subsequent modification. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.

Gene Wiki entry for RPL30 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL30 Gene

Genomics for RPL30 Gene

Regulatory Elements for RPL30 Gene

Enhancers for RPL30 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around RPL30 on UCSC Golden Path with GeneCards custom track

Promoters for RPL30 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for RPL30 Gene

98,024,851 bp from pter
98,046,469 bp from pter
21,619 bases
Minus strand

Genomic View for RPL30 Gene

Genes around RPL30 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPL30 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPL30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL30 Gene

Proteins for RPL30 Gene

  • Protein details for RPL30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    60S ribosomal protein L30
    Protein Accession:
    Secondary Accessions:
    • B2R591
    • P04645
    • Q502Z6

    Protein attributes for RPL30 Gene

    115 amino acids
    Molecular mass:
    12784 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPL30 Gene

neXtProt entry for RPL30 Gene

Post-translational modifications for RPL30 Gene

  • Ubiquitination at Lys 32, Lys 44, Lys 57, Lys 68, and Lys 87
  • Modification sites at PhosphoSitePlus

Other Protein References for RPL30 Gene

No data available for DME Specific Peptides for RPL30 Gene

Domains & Families for RPL30 Gene

Gene Families for RPL30 Gene

Suggested Antigen Peptide Sequences for RPL30 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ribosomal protein L30e family.
  • Belongs to the ribosomal protein L30e family.
genes like me logo Genes that share domains with RPL30: view

Function for RPL30 Gene

Molecular function for RPL30 Gene

GENATLAS Biochemistry:
60S ribosomal protein L30,12kDa,likely same as D8S1364E

Gene Ontology (GO) - Molecular Function for RPL30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding TAS 1577483
GO:0003735 structural constituent of ribosome TAS 1577483
GO:0005515 protein binding IPI 22720776
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RPL30: view
genes like me logo Genes that share phenotypes with RPL30: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPL30 Gene

Localization for RPL30 Gene

Subcellular locations from

Jensen Localization Image for RPL30 Gene COMPARTMENTS Subcellular localization image for RPL30 gene
Compartment Confidence
cytosol 5
extracellular 5
nucleus 5
mitochondrion 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for RPL30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 22720776
GO:0005737 cytoplasm IDA --
GO:0005829 cytosol TAS --
GO:0005925 focal adhesion IDA 21423176
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with RPL30: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RPL30 Gene

Pathways & Interactions for RPL30 Gene

genes like me logo Genes that share pathways with RPL30: view

Gene Ontology (GO) - Biological Process for RPL30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0006364 rRNA processing TAS --
GO:0006412 translation TAS 1577483
GO:0006413 translational initiation TAS --
GO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS --
genes like me logo Genes that share ontologies with RPL30: view

No data available for SIGNOR curated interactions for RPL30 Gene

Drugs & Compounds for RPL30 Gene

No Compound Related Data Available

Transcripts for RPL30 Gene

mRNA/cDNA for RPL30 Gene

Unigene Clusters for RPL30 Gene

Ribosomal protein L30:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RPL30 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d
SP1: - - - - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - -
SP5: - - - - -
SP6: - - -
SP7: - -
SP8: -
SP9: - - -

Relevant External Links for RPL30 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RPL30 Gene

mRNA expression in normal human tissues for RPL30 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for RPL30 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (7.4) and Pancreas (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RPL30 Gene

Protein tissue co-expression partners for RPL30 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RPL30 Gene:


SOURCE GeneReport for Unigene cluster for RPL30 Gene:

genes like me logo Genes that share expression patterns with RPL30: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RPL30 Gene

Orthologs for RPL30 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPL30 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RPL30 34
  • 94.2 (n)
  • 100 (a)
RPL30 35
  • 97 (a)
(Canis familiaris)
Mammalia RPL30 34
  • 93.04 (n)
  • 99.13 (a)
RPL30 35
  • 85 (a)
(Mus musculus)
Mammalia Rpl30 34
  • 94.2 (n)
  • 100 (a)
Rpl30 16
Rpl30 35
  • 100 (a)
(Pan troglodytes)
Mammalia RPL30 34
  • 99.42 (n)
  • 100 (a)
RPL30 35
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC100362027 34
  • 93.04 (n)
  • 100 (a)
(Monodelphis domestica)
Mammalia RPL30 35
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia RPL30 35
  • 88 (a)
(Gallus gallus)
Aves RPL30 34
  • 85.8 (n)
  • 99.13 (a)
RPL30 35
  • 85 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 99 (a)
-- 35
  • 96 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC89963 34
  • 85.59 (n)
  • 100 (a)
Str.750 34
(Danio rerio)
Actinopterygii rpl30 34
  • 81.16 (n)
  • 96.52 (a)
wufa93d05 34
rpl30 35
  • 95 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpL30 36
  • 81 (a)
RpL30 34
  • 70.37 (n)
  • 81.48 (a)
RpL30 35
  • 80 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003816 34
  • 72.12 (n)
  • 83.64 (a)
(Caenorhabditis elegans)
Secernentea rpl-30 36
  • 72 (a)
rpl-30 34
  • 63.36 (n)
  • 72.07 (a)
rpl-30 35
  • 70 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR478W 34
  • 61.67 (n)
  • 60 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E10847g 34
  • 60 (n)
  • 61 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL30 34
  • 62 (n)
  • 61 (a)
RPL30 35
  • 58 (a)
RPL30 37
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G36240 34
  • 66.67 (n)
  • 72.48 (a)
(Glycine max)
eudicotyledons Gma.15471 34
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.7503 34
(Oryza sativa)
Liliopsida Os01g0276000 34
  • 69.37 (n)
  • 73.87 (a)
(Triticum aestivum)
Liliopsida Ta.3371 34
(Zea mays)
Liliopsida Zm.12150 34
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13337 34
bread mold
(Neurospora crassa)
Ascomycetes NCU08963 34
  • 60.58 (n)
  • 61.54 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpl3002 34
  • 62.09 (n)
  • 69.61 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 79 (a)
Species where no ortholog for RPL30 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for RPL30 Gene

Gene Tree for RPL30 (if available)
Gene Tree for RPL30 (if available)

Paralogs for RPL30 Gene

genes like me logo Genes that share paralogs with RPL30: view

No data available for Paralogs for RPL30 Gene

Variants for RPL30 Gene

Sequence variations from dbSNP and Humsavar for RPL30 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1466428 -- 98,043,711(-) ACTAA(A/T)TTGAC intron-variant
rs1599909 -- 98,042,568(+) ATTTG(C/T)GTAGT intron-variant
rs1804308 -- 98,041,826(-) AAGCA(C/T)GCCAG reference, missense
rs1804309 -- 98,042,699(-) AACTG(A/G)GCACA reference, missense
rs1804311 -- 98,041,780(-) AAATT(C/T)CACCT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for RPL30 Gene

Variant ID Type Subtype PubMed ID
esv2674440 CNV deletion 23128226

Variation tolerance for RPL30 Gene

Residual Variation Intolerance Score: 49.5% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RPL30 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPL30 Gene

Disorders for RPL30 Gene

Relevant External Links for RPL30

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RPL30 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPL30 Gene

Publications for RPL30 Gene

  1. Crystallization and preliminary X-ray structure analysis of human ribosomal protein L30e. (PMID: 22139155) Kawaguchi A. … Tanaka I. (Acta Crystallogr. F 2011) 3 4 65
  2. Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. (PMID: 16968546) De Bortoli M. … Kim J.Y. (BMC Cancer 2006) 3 22 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PMID: 11875025) Yoshihama M. … Kenmochi N. (Genome Res. 2002) 3 4 65
  5. The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome. (PMID: 1577483) Feo S. … Fried M. (Genomics 1992) 2 3 65

Products for RPL30 Gene

Sources for RPL30 Gene

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