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RPL27A Gene

protein-coding   GIFtS: 63
GCID: GC11P008703

Ribosomal Protein L27a

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ribosomal Protein L27a1 2
60S Ribosomal Protein L27a2
L27A2

External Ids:    HGNC: 103291   Entrez Gene: 61572   Ensembl: ENSG000001664417   OMIM: 6036375   UniProtKB: P467763   
ORGUL members:         

Export aliases for RPL27A gene to outside databases

Previous GC identifers: GC11P009474 GC11P009150 GC11P008743 GC11P008668 GC11P008660 GC11P008371


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL27A Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family
of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers
compared to adjacent normal tissues has been observed, although no correlation between the level of expression
and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple
processed pseudogenes derived from this gene are dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL27A Gene:
RPL27A (ribosomal protein L27a) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL27A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL27A gene promoter:
         AML1a   GCNF   c-Ets-1   RORalpha2   PPAR-gamma1   FOXO4   GCNF-1   FOXO1a   GCNF-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL27A promoter sequence
   Search Chromatin IP Primers for RPL27A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL27A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15

RPL27A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL27A gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P008703:  view genomic region     (about GC identifiers)

Start:
8,703,958 bp from pter      End:
8,736,306 bp from pter
Size:
32,349 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RL27A_HUMAN, P46776 (See protein sequence)
Recommended Name: 60S ribosomal protein L27a  
Size: 148 amino acids; 16561 Da
1 PDB 3D structure from and Proteopedia for RPL27A:
3J3B (3D)    
Secondary accessions: B2R4B3

Explore the universe of human proteins at neXtProt for RPL27A: NX_P46776

Explore proteomics data for RPL27A at MOPED

Post-translational modifications: 

  • Hydroxylated on His-39 by MINA1
  • Ubiquitination2 at Lys47, Lys55, Lys77, Lys92, Lys94
  • Modification sites at PhosphoSitePlus

  • See RPL27A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000981.1  
    ENSEMBL proteins: 
     ENSP00000346015   ENSP00000433259   ENSP00000431849   ENSP00000435333   ENSP00000435081  
     ENSP00000432671   ENSP00000431565   ENSP00000437118   ENSP00000433766  
    Reactome Protein details: P46776

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    2 InterPro protein domains:
     IPR021131 Ribosomal_L18e/L15P
     IPR001196 Ribosomal_L15_CS

    Graphical View of Domain Structure for InterPro Entry P46776

    ProtoNet protein and cluster: P46776

    1 Blocks protein domain: IPB001196 Ribosomal protein L15

    UniProtKB/Swiss-Prot: RL27A_HUMAN, P46776
    Similarity: Belongs to the ribosomal protein L15P family


    Find genes that share domains with RPL27A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL27A:
    60S ribosomal protein L27A,16kDa

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS7772601
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding IPI--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RPL27A           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for RPL27A:
     Increased S DNA content  Nuclear 40S maturation defects  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 
     S arrest 

         14 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rpl27a):
     behavior/neurological  cellular  craniofacial  growth/size/body  hearing/vestibular/ear 
     hematopoietic system  immune system  integument  limbs/digits/tail  mortality/aging 
     nervous system  normal  pigmentation  tumorigenesis 

    Find genes that share phenotypes with RPL27A           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPL27A

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL27A:
    hsa-let-7e-5p (MIRT051684), hsa-mir-30c-5p (MIRT047910), hsa-mir-193b-3p (MIRT041251), hsa-mir-30a-3p (MIRT049914), hsa-mir-342-3p (MIRT043697), hsa-mir-15b-5p (MIRT046409), hsa-mir-99b-3p (MIRT038524), hsa-mir-484 (MIRT041902), hsa-mir-16-5p (MIRT031412), hsa-mir-1180-3p (MIRT035942), hsa-mir-296-3p (MIRT038513)

    Block miRNA regulation of human, mouse, rat RPL27A using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325

    Find genes that share ontologies with RPL27A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL27A About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease


    Find genes that share SuperPaths with RPL27A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL27A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL27A
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL27A (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL27A):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL27A
    Interactions:

        Search GeneGlobe Interaction Network for RPL27A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL27A (P467761, 2, 3 ENSP000003460154) via UniProtKB, MINT, STRING, and/or I2D (see all 469)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL4P365782, 3, ENSP000003114304MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=4 STRING: ENSP00000311430
    RPL11P629132, 3, ENSP000003636764MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000363676
    RPL26P612542, 3, ENSP000002938424MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000293842
    RPL35P427662, 3, ENSP000002594694MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000259469
    RPS15AP622442, 3, ENSP000003186464MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000318646
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPL27A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL27A (RL27A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPL27A gene (2 alternative transcripts): 
    NM_000990.4  NM_032650.1  

    Unigene Cluster for RPL27A:

    Ribosomal protein L27a
    Hs.523463  [show with all ESTs]
    Unigene Representative Sequence: NM_000990
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000314138(uc001mgs.4) ENST00000529227 ENST00000530585 ENST00000531978
    ENST00000524496 ENST00000534599 ENST00000532359 ENST00000530022 ENST00000526562
    ENST00000525981 ENST00000530913 ENST00000531102
    miRNA
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    hsa-miR-586 hsa-miR-548b-3p hsa-miR-1179
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QuantiTect SYBR Green Assays in human, mouse, rat RPL27A
      QuantiFast Probe-based Assays in human, mouse, rat RPL27A

    Additional mRNA sequence: 

    AK125453.1 AK311767.1 BC004284.1 BC005326.1 BC014919.1 BC020169.1 BC066326.1 U14968.1 

    Selected DOTS entries (see all 53):

    DT.451082  DT.95072701  DT.100894777  DT.100685013  DT.97863626  DT.92040607  DT.100685021  DT.100685029 
    DT.91668870  DT.101955251  DT.100685022  DT.120725941  DT.100800558  DT.96085467  DT.92047273  DT.86993305 
    DT.101987246  DT.121408570  DT.405560  DT.120726014  DT.95139231  DT.87007600  DT.100653590  DT.100058029 

    Selected AceView cDNA sequences (see all 1860):

    BQ678906 AI333086 BM688931 BE294028 AA988814 BQ058192 BU738257 BM967334 
    BQ962334 AI042231 BE267539 AI347427 BI906450 BM853704 BI771373 AI929559 
    BE615894 AI419426 BQ674595 AW138015 BQ066537 AA775819 BM672362 AU123085 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL27A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGGGAGTTT
    RPL27A Expression
    About this image


    RPL27A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
     
     Umbilical Cord (Extraembryonic Tissues)
    RPL27A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL27A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.523463
        Custom PCR Arrays for RPL27A
    Primer
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL27A gene from Selected species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl27a1 , 5 ribosomal protein L27A1, 5 90.99(n)1
    97.3(a)1
      7 (57.26 cM)5
    264511  NM_011975.31  NP_036105.21 
     1095191475 
    chicken
    (Gallus gallus)
    Aves RPL27A1 ribosomal protein L27a 80.18(n)
    92.57(a)
      770018  NM_001277663.1  NP_001264592.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    91(a)
    86(a)
    many → 1
    many → 1
    GL343770.1(32022-36559)
    2(112667925-112671412)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC053769.12   -- 78.12(n)    BC053769.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa93g122 wufa93g12 79.57(n)   336726  BC064441.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL27A1 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein L27A1
    68(a)3
    66.67(n)1
    69.23(a)1
      23
    336541  NM_001201760.21  NP_001188689.21 
    worm
    (Caenorhabditis elegans)
    Secernentea Y37E3.8a3
    Y37E3.81
    Y37E3.81 69(a)3
    65.52(n)1
    71.03(a)1
      I(2069723-2070606)3
    1717671  NM_058526.61  NP_490927.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL28(YGL103W)4
    RPL281
    Ribosomal protein of the large (60S) ribosomal subunit, more4
    RPL281
    60.59(n)1
    62.16(a)1
      7(310967-311927)4
    8527751, 4  NP_011412.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G706001 AT1G70600 68.28(n)
    66.21(a)
      843397  NM_105728.3  NP_177217.1 
    rice
    (Oryza sativa)
    Liliopsida BI803160.12   -- 74.25(n)    BI803160.1 


    ENSEMBL Gene Tree for RPL27A (if available)
    TreeFam Gene Tree for RPL27A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL27A gene
    4 SIMAP similar genes for RPL27A using alignment to 7 protein entries:     RL27A_HUMAN (see all proteins):
    FAM175A    PTPLA    L27a    RANBP3

    Find genes that share paralogs with RPL27A           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPL27A (see all 8)
    PGOHUM00000248393 PGOHUM00000234851 PGOHUM00000245039 PGOHUM00000258116 PGOHUM00000240446


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL27A (see all 131)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1116567351,2
    C--8702003(+) AAGGCG/-AGGGC 1 -- us2k11Minor allele frequency- -:0.00CSA 2
    rs610455881,2
    C,F--8702016(+) TAAGGC/TTTAAA 1 -- us2k11Minor allele frequency- T:0.14WA 118
    rs1397053081,2
    --8702024(+) AAACAC/GAGGAA 1 -- us2k10--------
    rs1820085441,2
    --8702035(+) GCACAC/TTGGGG 1 -- us2k10--------
    rs789662001,2
    F--8702036(+) CACATT/CGGGGA 1 -- us2k11Minor allele frequency- C:0.02EA 120
    rs1164438701,2
    F--8702052(+) AGAAAC/GAAAAG 1 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1843065621,2
    C--8702056(+) ACAAAA/GGGATA 1 -- us2k10--------
    rs1123699341,2
    C,F--8702073(+) CAGTGT/CAGTAG 1 -- us2k12Minor allele frequency- C:0.04CSA WA 120
    rs108401071,2
    C,F,A--8702142(+) CAAGAC/TAGAGA 1 -- us2k111Minor allele frequency- T:0.29NA CSA WA EA NS 522
    rs776637121,2
    C,F--8702213(+) CTGTAG/CAATGT 1 -- us2k12Minor allele frequency- C:0.01NA NS 270

    HapMap Linkage Disequilibrium report for RPL27A (8703958 - 8736306 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RPL27A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv499766OTHER Inversion21111241
    nsv7215OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL27A
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL27A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603637    OMIM disorders: --


    Find genes that share disorders with RPL27A           About GenesLikeMe


    Export disorders for RPL27A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL27A gene, integrated from 10 sources (see all 55):
    (articles sorted by number of sources associating them with RPL27A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 2, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    2. Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs. (PubMed id 7772601)1, 2, 3 Frigerio J.-M.... Iovanna J.L. (Biochim. Biophys. Acta 1995)
    3. Genomic structure and chromosome location of RPL27A/Rpl27a, the genes encoding human and mouse ribosomal protein L27A. (PubMed id 10449908)1, 2, 9 Kusuda J.... Hashimoto K. (Cytogenet. Cell Genet. 1999)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)
    7. Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription. (PubMed id 24140708)1 Wu T....Zhang D.D. (amp 2014)
    8. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. (PubMed id 23563607)1 Berndt S.I....Ingelsson E. (Nat. Genet. 2013)
    9. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    10. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6157 HGNC: 10329 AceView: RPL27A Ensembl:ENSG00000166441 euGenes: HUgn6157
    ECgene: RPL27A Kegg: 6157 H-InvDB: RPL27A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPL27A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPL27A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPL27A gene:
    Search GeneIP for patents involving RPL27A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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