Aliases for RPL27 Gene
External Ids for RPL27 Gene
Previous GeneCards Identifiers for RPL27 Gene
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]
GeneCards Summary for RPL27 Gene
RPL27 (Ribosomal Protein L27) is a Protein Coding gene. Diseases associated with RPL27 include Diamond-Blackfan Anemia 16 and Diamond-Blackfan Anemia. Among its related pathways are Viral mRNA Translation and Metabolism. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.
UniProtKB/Swiss-Prot for RPL27 Gene
Component of the large ribosomal subunit (PubMed:12962325). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (PubMed:25424902).