RPL26L1 Gene
protein-coding GIFtS: 53
GCID: GC05P172385
|
|
ribosomal protein L26-like 1(Previous name: ribosomal protein L26 pseudogene 1 ) (Previous symbol: RPL26P1)
| |
Aliases for RPL26L1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Ribosomal Protein L26-Like 11 2 | | RPL26P11 2 3 | | Ribosomal Protein L26 Pseudogene 11 2 | | 60S Ribosomal Protein L26-Like 12 | | Ribosomal Protein L26 Homolog2 |
Export aliases for RPL26L1 gene to outside databasesPrevious GC identifers: GC05P172643 GC05P173088 GC05P172316 GC05P172367 GC05P172319 GC05P167481 |
Summaries for RPL26L1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for RPL26L1: This gene encodes a protein that shares high sequence similarity with ribosomal protein L26. It is not currently knownwhether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independentof the ribosome. Transcript variants utilizing alternative polyA signals exist. (provided by RefSeq, Jul 2008)
|
Genomic Views for RPL26L1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RPL26L1 gene promoter: SRF AML1a SRF (504 AA) Nkx2-5 CREB Pax-3 deltaCREB STAT3 ATF Other transcription factors
Search SABiosciences Chromatin IP Primers for RPL26L1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL26L1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35.1 Ensembl cytogenetic band: 5q35.1 HGNC cytogenetic band: 5q35.2RPL26L1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P172385: view genomic region
(about GC identifiers)
Start:
|
172,385,732 bp from pter |
End:
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172,396,774 bp from pter |
Size:
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11,043 bases |
Orientation:
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plus strand |
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Proteins for RPL26L1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: RL26L_HUMAN, Q9UNX3 (See
protein sequence)Recommended Name: 60S ribosomal protein L26-like 1 Size: 145 amino acids; 17256 Da
Secondary accessions: B3KY82 D3DQM0Explore the universe of human proteins at neXtProt for RPL26L1: NX_Q9UNX3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UNX3 RPL26L1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057177.1 ENSEMBL proteins: ENSP00000428177 ENSP00000428223 ENSP00000265100 ENSP00000430147 ENSP00000429783 ENSP00000430673 Reactome Protein details: Q9UNX3 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- | | GO:0015934 | large ribosomal subunit |
IEA | -- |
RPL26L1 for ontologies About GeneDecksing
RPL26L1 Antibody Products: Assay Products for RPL26L1: |
Protein
Domains / Families for RPL26L1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPL26L1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UNX3ProtoNet protein and cluster: Q9UNX3 1 Blocks protein family: IPB006646 KOW (Kyprides
UniProtKB/Swiss-Prot: RL26L_HUMAN, Q9UNX3Similarity: Belongs to the ribosomal protein L24P family |
Function for RPL26L1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL26L1 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL26L1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
IEA | -- |
RPL26L1 for ontologies About GeneDecksing
|
Pathways & Interactions for RPL26L1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of PB1-F2 | | | 2 | Metabolism of mRNA | | | 3 | Disease | | | 4 | Generic Transcription Pathway | | | 5 | Asparagine N-linked glycosylation | |
Pathway sources See GeneCards unified pathways Show all pathways
5/28
Reactome Pathways for RPL26L1 (see all 28)
1
Kegg Pathway (Kegg details for RPL26L1):
RPL26L1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL26L1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/183 Interacting proteins for RPL26L1 (Q9UNX33 ENSP000002651004) via UniProtKB, MINT, STRING, and/or I2D (see all 183)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
TAS | -- | | GO:0006412 | translation |
TAS | -- | | GO:0006413 | translational initiation |
TAS | -- | | GO:0006414 | translational elongation |
TAS | -- | | GO:0006415 | translational termination |
TAS | -- |
RPL26L1 for ontologies About GeneDecksing
|
Drugs & Compounds for RPL26L1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for RPL26L1
3 DrugBank Compounds for RPL26L1 About this table
Search CenterWatch for drugs/clinical trials and news about RPL26L1 / RL26L 
|
Transcripts for RPL26L1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for RPL26L1 gene: NM_016093.2 Unigene Cluster for RPL26L1: Ribosomal protein L26-like 1 Hs.546390 [show with all ESTs]Unigene Representative Sequence: CB9949496 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000519974 ENST00000521476 ENST00000265100(uc003mcc.3) ENST00000519239 ENST00000519522 ENST00000519156
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPL26L1 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPL26L1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RPL26L1 (NM_016093) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPL26L1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL26L1  |
Additional cDNA sequence: AF083248.1 AK128872.1 BC017360.2 BC070192.1 8 DOTS entries: DT.95275024 DT.95275023 DT.75127312 DT.100784311 DT.120800819 DT.120800828 DT.100784312 DT.99939243 24/129 AceView cDNA sequences (see all 129): AI350075 BQ432293 BQ684711 BC017360 BU193755 BM820632 AK128872 CB111373 BU624106 AI085368 BX280748 AI253648 AA704992 AA313166 BX280686 AA460318 BM912184 BU163951 AI419260 BM423868 NM_016093 CB111455 BQ015377 BI335849 GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for RPL26L1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for RPL26L1
|
Expression for RPL26L1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RPL26L1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCCATCCGCA
About this image See RPL26L1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for RPL26L1
SOURCE GeneReport for Unigene cluster: Hs.546390 SABiosciences Custom PCR Arrays for RPL26L1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPL26L1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPL26L1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPL26L1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPL26L1 |
Orthologs for RPL26L1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RPL26L1 gene from 8/29 species (see all 29) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
RPL26L11 |
ribosomal protein L26-like 1 |
82.99(n) 98.62(a) |
  |
396400 XM_001231498.2 XP_001231499.2 |
lizard (Anolis carolinensis) |
Reptilia |
RPL266 |
-- |
99(a) |
possible ortholog |
2(124479622-124483576) |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
1420007092 |
-- |
81.63(n) |
  |
142000709 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.269562 |
Danio rerio cDNA clone MGC66190 IMAGE5612305, complete more |
77.89(n) |
  |
BC055538.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG68463 |
protein biosynthesis structural constituent of more |
71(a) |
  |
75E4 -- |
worm (Caenorhabditis elegans) |
Secernentea |
rpl-263 |
ribosomal protein L26 like |
61(a) |
  |
II(8602715-8603469) -- |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT3G499106AT5G675106 |
60S ribosomal protein L26-2 |
70(a)65(a) |
many ↔ manymany ↔ many |
3(18504256-18504967) 5(26937813-26938451) |
rice (Oryza sativa) |
Liliopsida |
Os.93172 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
78.99(n) |
  |
AK121546.1 |
Species with no ortholog for RPL26L1
ENSEMBL Gene Tree for RPL26L1 (if available) TreeFam Gene Tree for RPL26L1 (if available)  |
Paralogs for RPL26L1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for RPL26L1 gene
- ENSG000002638092 RPL262
2 SIMAP similar genes for RPL26L1 using alignment to 3 protein entries: RL26L_HUMAN (see all proteins):KRBA2 RPL26
RPL26L1 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for RPL26L1 PGOHUM00000238826 PGOHUM00000259003 PGOHUM00000235186 PGOHUM00000257250
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Genomic Variants for RPL26L1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 5 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for RPL26L1 (172385732 - 172396774 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for RPL26L1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPL26L1 |
|
Disorders
/ Diseases for RPL26L1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RPL26L1 for disorders About GeneDecksing
4 diseases for RPL26L1: About MalaCardsdiamond-blackfan anemia lung cancer anemia malaria 1 disease from the University of Copenhagen DISEASES database for RPL26L1:Diamond-Blackfan anemia Export disorders for RPL26L1 gene to outside databases
|
Publications for RPL26L1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RPL26L1 gene, integrated from 9 sources (see all 17): (articles sorted by number of sources associating them with RPL26L1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Shotgun proteomics and network analysis of ubiquitin-r elated proteins from human breast carcinoma epithelial cells. (PubMed id 21853274)1 Zhou J....Liang S. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- Global profiling of protease cleavage sites by chemos elective labeling of protein N-termini. (PubMed id 19892738)2 Xu G....Jaffrey S.R. (2009)
|
External Searches for RPL26L1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RPL26L1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RPL26L1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RPL26L1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for RPL26L1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RPL26L1 gene: Search GeneIP for patents involving RPL26L1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for RPL26L1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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 | | RPL26L1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | ThermoFisher Antibodies for RPL26L1 |
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