Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RPL24 Gene

Aliases for RPL24 Gene

  • Ribosomal Protein L24 2 3
  • 60S Ribosomal Protein L30 3 4
  • Epididymis Secretory Protein Li 310 3
  • 60S Ribosomal Protein L24 3
  • Ribosomal Protein L30 3
  • HEL-S-310 3
  • L24 3

External Ids for RPL24 Gene

Summaries for RPL24 Gene

Entrez Gene Summary for RPL24 Gene

  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from S. cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

GeneCards Summary for RPL24 Gene

RPL24 (Ribosomal Protein L24) is a Protein Coding gene. Among its related pathways are Disease and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include RNA binding and structural constituent of ribosome.

Gene Wiki entry for RPL24 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL24 Gene

Genomics for RPL24 Gene

Genomic Location for RPL24 Gene

Start:
101,681,090 bp from pter
End:
101,686,782 bp from pter
Size:
5,693 bases
Orientation:
Minus strand

Genomic View for RPL24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RPL24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL24 Gene

Regulatory Elements for RPL24 Gene

Proteins for RPL24 Gene

  • Protein details for RPL24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P83731-RL24_HUMAN
    Recommended name:
    60S ribosomal protein L24
    Protein Accession:
    P83731
    Secondary Accessions:
    • B2R4Y3
    • P38663
    • Q6IBS3

    Protein attributes for RPL24 Gene

    Size:
    157 amino acids
    Molecular mass:
    17779 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RPL24 Gene

neXtProt entry for RPL24 Gene

Proteomics data for RPL24 Gene at MOPED

Post-translational modifications for RPL24 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys12, Lys27, Lys35, Lys43, Lys93, Lys131, and Lys147

Other Protein References for RPL24 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for RPL24 Gene

Domains for RPL24 Gene

Gene Families for RPL24 Gene

HGNC:
  • RPL :L ribosomal proteins

Protein Domains for RPL24 Gene

UniProtKB/Swiss-Prot:

RL24_HUMAN
Family:
  • Belongs to the ribosomal protein L24e family.:
    • P83731
genes like me logo Genes that share domains with RPL24: view

Function for RPL24 Gene

Molecular function for RPL24 Gene

GENATLAS Biochemistry: 60S ribosomal protein L24

Gene Ontology (GO) - Molecular Function for RPL24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding TAS 9582194
GO:0003735 structural constituent of ribosome NAS 12962325
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RPL24: view
genes like me logo Genes that share phenotypes with RPL24: view

miRNA for RPL24 Gene

miRTarBase miRNAs that target RPL24

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RPL24 Gene

Localization for RPL24 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RPL24 Gene COMPARTMENTS Subcellular localization image for RPL24 gene
Compartment Confidence
cytosol 5
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for RPL24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
GO:0005840 ribosome --
GO:0016020 membrane IDA 19946888
GO:0022625 cytosolic large ribosomal subunit IDA 12962325
GO:0070062 extracellular exosome IDA 20458337
genes like me logo Genes that share ontologies with RPL24: view

Pathways for RPL24 Gene

genes like me logo Genes that share pathways with RPL24: view

Pathways by source for RPL24 Gene

1 GeneGo (Thomson Reuters Life Sciences Research) pathway for RPL24 Gene
1 BioSystems pathway for RPL24 Gene

Gene Ontology (GO) - Biological Process for RPL24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000027 ribosomal large subunit assembly IEA --
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS --
GO:0006412 translation TAS --
GO:0006413 translational initiation TAS --
GO:0006414 translational elongation TAS --
genes like me logo Genes that share ontologies with RPL24: view

Transcripts for RPL24 Gene

Unigene Clusters for RPL24 Gene

Ribosomal protein L24:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RPL24 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1: - -
SP2: -
SP3: - -
SP4:

Relevant External Links for RPL24 Gene

GeneLoc Exon Structure for
RPL24
ECgene alternative splicing isoforms for
RPL24

Expression for RPL24 Gene

mRNA expression in normal human tissues for RPL24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for RPL24 Gene

SOURCE GeneReport for Unigene cluster for RPL24 Gene Hs.477028

genes like me logo Genes that share expressions with RPL24: view

Orthologs for RPL24 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPL24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 100 (a)
OneToMany
RPL24 36
  • 100 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia RPL24 36
  • 94.48 (n)
  • 100 (a)
RPL24 37
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RPL24 36
  • 94.27 (n)
  • 100 (a)
RPL24 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rpl24 36
  • 91.51 (n)
  • 100 (a)
Rpl24 16
RPL24 37
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RPL24 37
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RPL24 37
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rpl24 36
  • 90.66 (n)
  • 100 (a)
chicken
(Gallus gallus)
Aves RPL24 36
  • 80.04 (n)
  • 97.45 (a)
RPL24 37
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RPL24 37
  • 92 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.24759 36
tropical clawed frog
(Silurana tropicalis)
Amphibia rpl24 36
  • 76.56 (n)
  • 86.45 (a)
Str.1374 36
zebrafish
(Danio rerio)
Actinopterygii -- 36
rpl24 36
  • 74.31 (n)
  • 89.17 (a)
rpl24 37
  • 89 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010216 36
  • 59.48 (n)
  • 64.71 (a)
fruit fly
(Drosophila melanogaster)
Insecta RpL24 36
  • 57.63 (n)
  • 60.65 (a)
RpL24 37
  • 66 (a)
OneToOne
CG9282 38
  • 70 (a)
worm
(Caenorhabditis elegans)
Secernentea rpl-24.1 36
  • 52.78 (n)
  • 48.72 (a)
rpl-24.1 37
  • 52 (a)
OneToOne
rpl-24.1 38
  • 51 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR477C 36
  • 55.45 (n)
  • 57.94 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL24A 36
  • 56.36 (n)
  • 57.27 (a)
RPL24A 37
  • 50 (a)
OneToMany
RPL24B 37
  • 50 (a)
OneToMany
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E10869g 36
  • 56.39 (n)
  • 58.88 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons STV1 36
  • 57.8 (n)
  • 53.21 (a)
rice
(Oryza sativa)
Liliopsida Os05g0486700 36
  • 55.76 (n)
  • 50.91 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU03150 36
  • 56.06 (n)
  • 57.27 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpl2402 36
  • 56.97 (n)
  • 63.64 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4973 37
  • 64 (a)
OneToOne
Species with no ortholog for RPL24:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPL24 Gene

ENSEMBL:
Gene Tree for RPL24 (if available)
TreeFam:
Gene Tree for RPL24 (if available)

Paralogs for RPL24 Gene

Selected SIMAP similar genes for RPL24 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RPL24: view

No data available for Paralogs for RPL24 Gene

Variants for RPL24 Gene

Sequence variations from dbSNP and Humsavar for RPL24 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1061543 -- 101,682,841(-) CATCT(C/T)TTGCT reference, missense
rs1138818 -- 101,680,739(+) GAGCT(C/G)AAGTG downstream-variant-500B
rs1804331 -- 101,681,160(-) TTCAG(A/C/T)TCCCC missense, reference
rs2303471 -- 101,686,048(-) TGGGC(C/T)TCAGT intron-variant
rs2303472 -- 101,686,021(-) CCAGA(A/G)CTAGC intron-variant

Relevant External Links for RPL24 Gene

HapMap Linkage Disequilibrium report
RPL24

No data available for Structural Variations from Database of Genomic Variants (DGV) for RPL24 Gene

Disorders for RPL24 Gene

No disorders were found for RPL24 Gene.

No data available for UniProtKB/Swiss-Prot for RPL24 Gene

Publications for RPL24 Gene

  1. A map of 75 human ribosomal protein genes. (PMID: 9582194) Kenmochi N. … Page D.C. (Genome Res. 1998) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30. (PMID: 8428672) Johnson K.R. (Gene 1993) 3 4
  4. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. (PMID: 11875025) Yoshihama M. … Kenmochi N. (Genome Res. 2002) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for RPL24 Gene

Sources for RPL24 Gene

Back to Top

Content