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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL23AP7 Gene

pseudogene   GIFtS: 26
GCID: GC02M114370

ribosomal protein L23a pseudogene 7

  Search for RPL23AP7
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ribosomal Protein L23a Pseudogene 71 2
RPL23AL11 2
BA395L14.91
RPL23A_6_2672

External Ids:    HGNC: 173361   Entrez Gene: 1184332   Ensembl: ENSG000002403567   
ORGUL members:         
NONCODE:n387141 n383723 n387140    

Export aliases for RPL23AP7 gene to outside databases

Previous GC identifers: GC02U990310 GC02M112289 GC02M114275 GC02M114464 GC02M114085 GC07M000122


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022135.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL23AP7 gene promoter:
         GR   HOXA3   AML1a   GR-beta   NF-kappaB   FOXJ2 (long isoform)   GR-alpha   FOXJ2   Zic3   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for RPL23AP7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL23AP7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14   Ensembl cytogenetic band:  2q13   HGNC cytogenetic band: 2q14

RPL23AP7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL23AP7 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M114370:  view genomic region     (about GC identifiers)

Start:
114,368,079 bp from pter      End:
114,384,715 bp from pter
Size:
16,637 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 122,356-122,791     
ORGUL member locations:
Legend (see complete legend)

  • n387140
  • n383723
  • n387141
114368815 114376765 114384715 chr2

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB: --


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
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miRNA
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL23AP7

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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About This Section

Unigene Clusters for RPL23AP7:

Ribosomal protein L23a pseudogene 7
Hs.595056  [show with all ESTs], Hs.720253  [show with all ESTs]
Unigene Representative Sequences: NR_024528, AK055264
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000416673(uc010yxy.1 uc002tkk.2 uc010yxz.1 uc010yya.2)
ENST00000391616(uc010yyb.2) ENST00000449021

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Additional cDNA sequence: AK055264.1 

24 DOTS entries:

DT.120990772  DT.120990824  DT.95267259  DT.99984608  DT.120643081  DT.442163  DT.87014721  DT.91779511 
DT.92414392  DT.97834207  DT.120990776  DT.91745715  DT.97858298  DT.100044822  DT.120990770  DT.95239254 
DT.100044823  DT.100819036  DT.102840983  DT.120860828  DT.120958540  DT.121131837  DT.121473627  DT.95264362 

24/100 AceView cDNA sequences (see all 100):

CB159401 AW959980 AA025372 BQ776511 CA306343 BQ776826 AA919161 F02781 
AA365219 BM803758 BG335018 BM689726 BM554935 AA862479 BQ018462 BQ718297 
H12200 BG438235 BM911701 BE746978 CA443501 AA026523 BE300890 BI837112 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RPL23AP7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAACTTAAG

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
Genevestigator expression for RPL23AP7

SOURCE GeneReport for Unigene clusters: Hs.595056 Hs.720253
    SABiosciences Custom PCR Arrays for RPL23AP7
Primer
Products:
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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

ENSEMBL Gene Tree for RPL23AP7 (if available)
TreeFam Gene Tree for RPL23AP7 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/130 NCBI SNPs in RPL23AP7 are shown (see all 130    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs39825551,2
--114368540(+) TAACCA/GTCAAA 3 -- ds50010--------
rs17395001,2
--114368544(+) CGTCAA/GAATAT 3 -- ds50011Minor allele frequency- G:0.00NA 2
rs39825571,2
--114368574(+) gaaatC/Tgtgtt 3 -- ds50010--------
rs1870247641,2
--114368897(+) ATCTAA/TTAATG 3 -- nc-transcript-variant0--------
rs2013614431,2
F--114369511(+) TGCTTG/CTTGGC 3 -- nc-transcript-variant1Minor allele frequency- C:0.03EU 149
rs2010906071,2
C,F--114369542(+) CAAGCG/ATGTTG 3 -- nc-transcript-variant1Minor allele frequency- A:0.11EU 385
rs1827112721,2
C,F--114369557(+) CTTCTA/GTCTTC 3 -- nc-transcript-variant1Minor allele frequency- G:0.04EU 163
rs1123371691,2
C,F--114369629(+) TCCTGG/TGGGTG 3 -- nc-transcript-variant1Minor allele frequency- T:0.04EU 275
rs1404309711,2
--114369646(+) TGAGGA/CTATCT 3 -- nc-transcript-variant0--------
rs1917971991,2
--114369669(+) GAGTCA/GCAGTG 3 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for RPL23AP7 (114368079 - 114384715 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RPL23AP7
     1 CNV: 3386

SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for RPL23AP7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RPL23AP7)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Comparative analysis of processed ribosomal protein p seudogenes in four mammalian genomes. (PubMed id 19123937)1, 3 Balasubramanian S....Gerstein M. (2009)
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
  6. Nucleotide sequence of a cDNA clone (SUBT1) partly homologous to a human subtelomeric repeat sequence. (PubMed id 8799457)1 Lagercrantz J. and Lagercrantz S. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
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OMIM
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  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 118433 HGNC: 17336 AceView: RPL23AP7 Ensembl:ENSG00000240356 euGenes: HUgn118433
ECgene: RPL23AP7 H-InvDB: RPL23AP7

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for RPL23AP7 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for RPL23AP7 gene:
Search GeneIP for patents involving RPL23AP7

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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