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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL23A Gene

protein-coding   GIFtS: 59
GCID: GC17P027046

ribosomal protein L23a
 Explore 8 diseases affiliated with
RPL23A via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RPL23A    

Aliases
for RPL23A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ribosomal Protein L23a1 2
L23A1 2
60S Ribosomal Protein L23a2
MDA202
Melanoma Differentiation-Associated Gene 202

External Ids:    HGNC: 103171   Entrez Gene: 61472   Ensembl: ENSG000001982427   OMIM: 6023265   UniProtKB: P627503   

Export aliases for RPL23A gene to outside databases

Previous GC identifers: GC17P026892 GC17P028946 GC17P027192 GC17P024072


Summaries
for RPL23A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RPL23A:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of
ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in
mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S
rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located
in its third, first, second, and fourth introns, respectively. As is typical for genes encoding ribosomal proteins,
there are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RL23A_HUMAN, P62750
Function: This protein binds to a specific region on the 26S rRNA (By similarity)

Gene Wiki entry for RPL23A


Genomic Views
for RPL23A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL23A gene promoter:
         SRF   HFH-3   ATF-2   SRF (504 AA)   Tal-1beta   E47   CRE-BP1   FOXI1   PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RPL23A promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL23A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL23A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

RPL23A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL23A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P027046:  view genomic region     (about GC identifiers)

Start:
 27,046,411 bp from pter      End:
 27,051,377 bp from pter
Size:
 4,967 bases      Orientation:
 plus strand

Proteins
for RPL23A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RL23A_HUMAN, P62750 (See protein sequence)
Recommended Name: 60S ribosomal protein L23a  
Size: 156 amino acids; 17695 Da
Secondary accessions: B2R5B2 P29316 P39024 Q92774

Explore the universe of human proteins at neXtProt for RPL23A: NX_P62750

Post-translational modifications:

  • N-terminus is methylated by METTL11A/NTM1 (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62750

    • RPL23A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_000975.2  
    ENSEMBL proteins: 
     ENSP00000389103   ENSP00000468172   ENSP00000378396   ENSP00000468402   ENSP00000347969  
     ENSP00000466425   ENSP00000465342   ENSP00000468370  
    Reactome Protein details: P62750
    Human Recombinant Protein Products: 
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    Novus Biologicals RPL23A Proteins
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RPL23A

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA9687515
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit NAS9417910
    GO:0031932colocalizes with TORC2 complex ISS--


    RPL23A for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RPL23A

    Protein Domains /
    Families
    for RPL23A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RPL23A for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR012678 Ribosomal_L23/L15e_core_dom
     IPR019985 Ribosomal_L23
     IPR001014 Ribosomal_L23/L25_CS
     IPR005633 Ribosomal_L23/L25_N
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry P62750

    ProtoNet protein and cluster: P62750

    2 Blocks protein families:
    IPB001014 Ribosomal L23 protein
    IPB005633 Ribosomal protein L23


    UniProtKB/Swiss-Prot: RL23A_HUMAN, P62750
    Similarity: Belongs to the ribosomal protein L23P family


    Function
    for RPL23A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RL23A_HUMAN, P62750
    Function: This protein binds to a specific region on the 26S rRNA (By similarity)

         Genatlas biochemistry entry for RPL23A:
    60S ribosomal protein L23A

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL23A
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate RPL23A (see all 12):
    hsa-miR-203 hsa-miR-676 hsa-miR-3166 hsa-miR-1324 hsa-miR-3126-5p hsa-miR-378b hsa-miR-146a* hsa-miR-422a
    SwitchGear 3'UTR luciferase reporter plasmid: RPL23A 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding IPI9687515
    GO:0019843rRNA binding IEA--


    RPL23A for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for RPL23A:
     Decreased cell number, increas  Decreased viability  Decreased viability of wild-ty  Increased gamma-H2AX phosphory 
     S arrest 


    Pathways & Interactions
    for RPL23A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    		Viral Protein Synthesis1.00
    		Cytoplasmic Ribosomal Proteins0.86
    		Viral mRNA Translation1.00
    		CFTR translational fidelity (class I mutations)0.83
    		Influenza Viral RNA Transcription and Replication1.00
    		SMG6 Cleaves mRNA with Premature Termination Codon0.80
    		Synthesis of nascent polypeptide containing signal sequence1.00
    		L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Metabolism of mRNA
    		Metabolism of mRNA1.00
    		Metabolism of RNA0.92
    3Disease
    		Disease1.00
    4Generic Transcription Pathway
    		Gene Expression0.46
    5Asparagine N-linked glycosylation
    		Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL23A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL23A 
        Cytoplasmic Ribosomal Proteins

    5/28        Reactome Pathways for RPL23A (see all 28)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL23A):
        Ribosome


    RPL23A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL23A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/792 Interacting proteins for RPL23A (P627501, 2, 3 ENSP000003891034) via UniProtKB, MINT, STRING, and/or I2D (see all 792)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LYARQ9NX581, 2, 3EBI-353254,EBI-713507 MINT-6488590 I2D: score=2 
    RPL4P365782, 3, ENSP000003114304MINT-7945693 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=1 STRING: ENSP00000311430
    RPL11P629132, 3, ENSP000003636764MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=1 STRING: ENSP00000363676
    RPL19P840982, 3, ENSP000002254304MINT-7945693 MINT-6488590 MINT-6488791 I2D: score=1 STRING: ENSP00000225430
    RPL35P427662, 3, ENSP000002594694MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=1 STRING: ENSP00000259469
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPL23A for ontologies           About GeneDecksing



    Drugs & Compounds
    for RPL23A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RPL23A

    3 DrugBank Compounds for RPL23A    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about RPL23A / RL23A 

    Transcripts
    for RPL23A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RPL23A gene: 
    NM_000984.5  

    Unigene Cluster for RPL23A:

    Ribosomal protein L23a
    Hs.419463  [show with all ESTs]
    Unigene Representative Sequence: BF972099
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000422514(uc002hci.3 uc021ttu.1) ENST00000582736 ENST00000496182
    ENST00000394938 ENST00000394935 ENST00000355731 ENST00000472628 ENST00000578181
    ENST00000473896 ENST00000580755

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPL23A
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate RPL23A (see all 12):
    hsa-miR-203 hsa-miR-676 hsa-miR-3166 hsa-miR-1324 hsa-miR-3126-5p hsa-miR-378b hsa-miR-146a* hsa-miR-422a
    SwitchGear 3'UTR luciferase reporter plasmid: RPL23A 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPL23A (see all 6)
    OriGene siRNA: RPL23A
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AK130965.1 AK312123.1 BC014459.1 BC058041.1 BC070191.1 L13799.1 U02032.1 U37230.1 
    U43701.1 

    24/74 DOTS entries (see all 74):

    DT.99926704  DT.100742395  DT.91801750  DT.100055010  DT.92049415  DT.100742458  DT.100742498  DT.100742454 
    DT.91936191  DT.97869792  DT.100742433  DT.100040220  DT.120945082  DT.98083132  DT.97869757  DT.101958706 
    DT.97869782  DT.120898225  DT.101958731  DT.91779539  DT.98083127  DT.100742472  DT.100742410  DT.102843807 

    24/3749 AceView cDNA sequences (see all 3749):

    BQ939593 BF111914 BM757617 BF026421 BU753940 BU502629 BG766966 BM761979 
    AI720899 BM674807 BU838820 R81894 BQ028691 AI299151 BM749717 BE644735 
    BG758576 BU931920 BQ070076 BM818231 BQ670259 AJ709220 BE673784 AA977953 

    GeneLoc Exon Structure


    Expression
    for RPL23A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL23A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGAAGATAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See RPL23A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL23A

    SOURCE GeneReport for Unigene cluster: Hs.419463
        SABiosciences Custom PCR Arrays for RPL23A
    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for RPL23A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL23A gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rpl23a1 , 5 ribosomal protein L23A1, 5 89.74(n)1
    100(a)1    		   11 (46.74 cM)5
    2684491  NM_207523.21  NP_997406.11 
     781809325 
    chicken
    (Gallus gallus)    		 Aves RPL23A1 ribosomal protein L23a 84.09(n)
    98.71(a)    		   417574  XM_415820.3  XP_415820.3 
    lizard
    (Anolis carolinensis)    		 Reptilia RPL23A6
    		 --
    		 96(a)
    		 1 ↔ 1
    		 AAWZ02039090(1432-5401)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.251822 Xenopus laevis transcribed sequence with strong similarity more 82.56(n)    CB197461.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufa93f052 Transcribed sequence with strong similarity to protein more 81.95(n)    57074226 
    fruit fly
    (Drosophila melanogaster)    		 Insecta RpL23a3
    RpL23A1    		 protein biosynthesis structural constituent
    of more3
    Ribosomal protein L23A1    		 71(a)3
    62.8(n)1
    65.16(a)1    		   62A103
    382081  NM_079162.31  NP_523886.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea rpl-25.21 , 3 60S ribosomal protein3
    Protein RPL-25.21    		 65(a)
    (best of 2)3
    64.58(n)1
    65.28(a)1    		   I(8337015-8337890)3
    1726171  NM_059862.21  NP_492263.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons RPL23AA1 60S ribosomal protein L23a-1 67.6(n)
    74.83(a)    		   818531  NM_001161093.1  NP_001154565.1 
    rice
    (Oryza sativa)    		 Liliopsida Os04g05010001 hypothetical protein 68.2(n)
    75(a)    		   4336307  NM_001059761.2  NP_001053226.2 


    ENSEMBL Gene Tree for RPL23A (if available)
    TreeFam Gene Tree for RPL23A (if available) 

    Paralogs
    for RPL23A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL23A gene
    1 SIMAP similar gene for RPL23A using alignment to 7 protein entries:     RL23A_HUMAN (see all proteins):
    DKFZp547I014

    RPL23A for paralogs           About GeneDecksing


    5/104 Pseudogenes.org Pseudogenes for RPL23A (see all 104)
    PGOHUM00000262834 PGOHUM00000238615 PGOHUM00000238911 PGOHUM00000262837 PGOHUM00000242490


    Genomic Variants
    for RPL23A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/125 NCBI SNPs in RPL23A are shown (see all 125)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1479788651,2
    		--27045076(+) GATAGA/GGACTC 10 -- int1 us2k10--------
    rs1505939691,2
    		F--27045360(+) AAGGGG/TGTGCC 10 -- us2k11Minor allele frequency- T:0.03NS 140
    rs1434660911,2
    		C,--27045445(+) AGATT-/GTGAGG 10 -- us2k10--------
    rs1386179311,2
    		F--27045526(+) CTTCGG/TGGTGG 10 -- us2k11Minor allele frequency- T:0.01NS 140
    rs175231611,2
    		C,H,--27045685(-) AGACAT/CGTCCC 11 -- us2k13Minor allele frequency- C:0.01NS NA 176
    rs1881271091,2
    		--27045838(+) GGAAGA/GGAAGA 11 -- us2k10--------
    rs1475732011,2
    		C,--27046072(+) TTATT-/TAT   
       TTATC    TTGAG     		11 -- us2k10--------
    rs1474022961,2
    		F--27046082(+) GACAGG/TGTCTC 11 -- us2k11Minor allele frequency- T:0.01NS 148
    rs99162401,2
    		C,F,H,--27046496(+) CTCTTG/AGCAGC 11 -- us2k18Minor allele frequency- A:0.01NS EA NA 990
    rs1808821701,2
    		--27046648(+) ACAATC/TCCCAT 11 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL23A (27046411 - 27051377 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RPL23A: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for RPL23A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RPL23A for disorders           About GeneDecksing

    OMIM gene information: 602326    OMIM disorders: --

    8 diseases for RPL23A:    About MalaCards
    pure red-cell aplasia    diamond-blackfan anemia    treacher collins syndrome    melanoma
    amebiasis    vaccinia    anemia    malaria

    1 Novoseek disease relationship for RPL23A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 14981896 (1)


    Export disorders for RPL23A gene to outside databases

    Publications
    for RPL23A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL23A gene, integrated from 9 sources (see all 50):
    (articles sorted by number of sources associating them with RPL23A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, sequencing, gene organization, and localization of the human ribosomal protein RPL23A gene. (PubMed id 9417910)1, 2, 3 Fan W.... Lennon G. (1997)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Identification of seven new human MHC class I region genes around the HLA-F locus. (PubMed id 8662070)1, 2 Fan W.... Weissman S.M. (1996)
    5. Suppression of human ribosomal protein L23A expression during cell growth inhibition by interferon-beta. (PubMed id 9053844)1, 9 Jiang H....Fisher P.B. (1997)
    6. Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. (PubMed id 9687515)1, 9 Jaekel S. and Goerlich D. (1998)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    External Searches for RPL23A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing RPL23A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6147 HGNC: 10317 AceView: RPL23A Ensembl:ENSG00000198242 euGenes: HUgn6147
    ECgene: RPL23A Kegg: 6147 H-InvDB: RPL23A

    Other Databases showing RPL23A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RPL23A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL23A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RPL23A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RPL23A gene:
    Search GeneIP for patents involving RPL23A

    GeneCards and IP:
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