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RPL19 Gene

protein-coding   GIFtS: 62
GCID: GC17P037356

Ribosomal Protein L19

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 4

Aliases
Ribosomal Protein L191 2
60S Ribosomal Protein L191 2
cytosolic1
N-Terminus Truncated1
L192

External Ids:    HGNC: 103121   Entrez Gene: 61432   Ensembl: ENSG000001082987   OMIM: 1804665   UniProtKB: P840983   
ORGUL members:    fRNAdb10:FR120472      
H-InvDB12:HIT000059733_01 HIT000059733_02    
NCBI13:AB055766    

Export aliases for RPL19 gene to outside databases

Previous GC identifers: GC17P036860 GC17P039354 GC17P037266 GC17P037731 GC17P034610


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL19 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family
of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there
are multiple processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL19 Gene:
RPL19 (ribosomal protein L19) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL19 Gene

fRNAdb sequence ontology for RPL19:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

View fRNAdb secondary structures for RPL19

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL19 gene promoter:
         GATA-3   SRF (504 AA)   p300   Max   POU2F1   POU2F1a   c-Myb   MRF-2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL19 promoter sequence
   Search Chromatin IP Primers for RPL19

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12

RPL19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL19 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P037356:  view genomic region     (about GC identifiers)

Start:
37,356,536 bp from pter      End:
37,360,980 bp from pter
Size:
4,445 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RL19_HUMAN, P84098 (See protein sequence)
Recommended Name: 60S ribosomal protein L19  
Size: 196 amino acids; 23466 Da
Sequence caution: Sequence=CAD97677.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for RPL19:
3J3B (3D)    
Secondary accessions: B2R4K2 P14118 P22908 Q502Y6 Q7Z6E4

Explore the universe of human proteins at neXtProt for RPL19: NX_P84098

Explore proteomics data for RPL19 at MOPED

Post-translational modifications: 

  • Citrullinated by PADI4 (By similarity)1
  • Ubiquitination2 at Lys21, Lys43, Lys46, Lys92, Lys128, Lys152, Lys153, Lys180, Lys181, Lys186
  • Modification sites at PhosphoSitePlus

  • See RPL19 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000972.1  
    ENSEMBL proteins: 
     ENSP00000225430   ENSP00000463985   ENSP00000464538   ENSP00000462938   ENSP00000463329  
    Reactome Protein details: P84098

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    5 InterPro protein domains:
     IPR027547 Ribosomal_L19/L19e
     IPR000196 Ribosomal_L19/L19e_dom
     IPR015972 Ribosomal_L19/L19e_dom1
     IPR023638 Ribosomal_L19/L19e_CS
     IPR015974 Ribosomal_L19/L19e_dom3

    Graphical View of Domain Structure for InterPro Entry P84098

    ProtoNet protein and cluster: P84098

    UniProtKB/Swiss-Prot: RL19_HUMAN, P84098
    Similarity: Belongs to the ribosomal protein L19e family


    Find genes that share domains with RPL19           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL19:
    60S ribosomal protein L19,23kDa

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS1577483
    GO:0003735structural constituent of ribosome TAS1577483
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RPL19           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPL19:
     Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RPL19

    miRNA
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    hsa-mir-23b-3p (MIRT046258), hsa-mir-27a-3p (MIRT050019), hsa-mir-100-5p (MIRT048491), hsa-mir-877-3p (MIRT036951), hsa-mir-27b-3p (MIRT046180), hsa-mir-1180-3p (MIRT035950)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion1
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----

    Find genes that share ontologies with RPL19           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL19 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease


    Find genes that share SuperPaths with RPL19           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL19
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL19
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL19 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL19):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL19
    Interactions:

        Search GeneGlobe Interaction Network for RPL19

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL19 (P840982, 3 ENSP000002254304) via UniProtKB, MINT, STRING, and/or I2D (see all 937)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL4P365782, 3, ENSP000003114304MINT-7945693 MINT-6488590 MINT-6488791 I2D: score=7 STRING: ENSP00000311430
    RPS3P233962, 3, ENSP000002785724MINT-7945693 MINT-6488590 MINT-6488791 I2D: score=3 STRING: ENSP00000278572
    RPL13P263732, 3, ENSP000003078894MINT-7945693 MINT-6488590 MINT-6488791 I2D: score=1 STRING: ENSP00000307889
    RPL26P612542, 3, ENSP000002938424MINT-6488590 MINT-6488791 I2D: score=7 STRING: ENSP00000293842
    RPL11P629132, 3, ENSP000003636764MINT-6488590 MINT-6488791 I2D: score=6 STRING: ENSP00000363676
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS1577483
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPL19           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL19 (RL19)

    3 DrugBank Compounds for RPL19    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235

    2 Novoseek inferred chemical compound relationships for RPL19 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adp 25.4 1 15254768 (1)
    atp 4.37 1 15254768 (1)



    Find genes that share compounds with RPL19           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    1 fRNAdb Secondary structure:


    REFSEQ mRNAs for RPL19 gene: 
    NM_000981.3  

    Unigene Cluster for RPL19:

    Ribosomal protein L19
    Hs.381061  [show with all ESTs]
    Unigene Representative Sequence: BF698920
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000225430(uc002hrq.1) ENST00000579374 ENST00000580333 ENST00000579260
    ENST00000582193 ENST00000585199 ENST00000577741 ENST00000577759
    miRNA
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    Additional mRNA sequence: 

    AK130962.1 AK223082.1 AK311858.1 AY157980.1 BC000530.2 BC013016.2 BC062709.1 BC066315.1 
    BC095445.1 BX537435.1 S56985.1 X63527.1 

    Selected DOTS entries (see all 57):

    DT.87018194  DT.100060117  DT.91776846  DT.100867441  DT.95199038  DT.92027119  DT.91860393  DT.91776853 
    DT.97759766  DT.97848231  DT.91776838  DT.95193257  DT.91935264  DT.100694343  DT.120907710  DT.100694331 
    DT.87079668  DT.100694325  DT.100694328  DT.97848233  DT.100694342  DT.100061155  DT.100694323  DT.120907712 

    Selected AceView cDNA sequences (see all 2255):

    BE545291 BM050426 AW576102 AW006489 BI551990 D57871 BE875702 BM768221 
    BM785493 AV705774 CA407156 AA353262 CA949970 BM989625 AA310187 BP379635 
    CD676604 AA312766 BQ651250 AJ708724 BE393362 CK825034 BI916807 BQ303057 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RPL19    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6
    SP1:                                                      
    SP2:              -                                       
    SP3:                                                      


    ECgene alternative splicing isoforms for RPL19

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL19 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAACACATCC
    RPL19 Expression
    About this image


    RPL19 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
     
     Larynx (Respiratory System)
    RPL19 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL19 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.381061
        Custom PCR Arrays for RPL19
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL19 gene from Selected species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl191 , 5 ribosomal protein L191, 5 92.01(n)1
    100(a)1
      11 (61.56 cM)5
    199211  NM_009078.21  NP_033104.21 
     980267105 
    chicken
    (Gallus gallus)
    Aves RPL191 ribosomal protein L19 84.18(n)
    99.49(a)
      420003  NM_001030929.1  NP_001026100.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL196
    ribosomal protein L19
    100(a)
    1 ↔ 1
    6(67405902-67415524)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC041546.12   -- 82.37(n)    BC041546.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.290552 Danio rerio ribosomal protein L19, mRNA (cDNA clone more 78.97(n)    BC062844.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL191 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein L191
    74(a)3
    70.47(n)1
    76.17(a)1
      2 60E103
    379951  NM_206219.11  NP_995941.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-191 , 3 60S ribosomal protein L193
    rpl-191
    69(a)3
    62.2(n)1
    65.98(a)1
      I(5484824-5485811)3
    1722011  NM_059207.51  NP_491608.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL19B(YBL027W)4
    RPL19B1
    Protein component of the large (60S) ribosomal subunit, more4
    RPL19B1
    54.3(n)1
    57.53(a)1
      2(168423-169376)4
    8522541, 4  NP_009526.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G022301 AT4G02230 63.84(n)
    71.19(a)
      828099  NM_116456.3  NP_192132.1 
    rice
    (Oryza sativa)
    Liliopsida AK059309.12   -- 74.41(n)    AK059309.1 


    ENSEMBL Gene Tree for RPL19 (if available)
    TreeFam Gene Tree for RPL19 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL19 gene

    Find genes that share paralogs with RPL19           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPL19 (see all 23)
    PGOHUM00000262853 PGOHUM00000250988 PGOHUM00000236918 PGOHUM00000234452 PGOHUM00000244054


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL19 (see all 166)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1851332261,2
    --37355958(+) GGTGTA/GTTCGA 1 -- us2k10--------
    rs1899359391,2
    --37355961(+) GTGTTC/TGATCG 1 -- us2k10--------
    rs1453728301,2
    --37355978(+) CATGCC/TTGCCG 1 -- us2k10--------
    rs1825539181,2
    --37356110(+) TCAATC/TTACTA 1 -- us2k10--------
    rs1871036671,2
    --37356198(+) CTAATA/GAAACA 1 -- us2k10--------
    rs733049821,2
    C,F--37356219(+) ACCCCG/CCGAAC 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs1500080831,2
    C--37356256(+) AAAAC-/CTCTCTC 1 -- us2k10--------
    rs773082481,2
    C,F--37356325(+) CCTTGC/ATGCGC 1 -- us2k13Minor allele frequency- A:0.07CSA WA NS 270
    rs1148810371,2
    C,F--37356561(+) GGCCCG/AAGCGA 1 -- ut512Minor allele frequency- A:0.01WA NS 268
    rs1467005651,2
    C--37356621(+) GGTCTC/TCATCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for RPL19 (37356536 - 37360980 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RPL19:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908203CNV Loss21882294
    nsv833441CNV Loss17160897
    nsv833440CNV Loss17160897
    nsv908204CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL19
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL19

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 180466OMIM information: 215500 601202 601251 605809 606579 607464 608631 609432 610185    

    Find genes that share disorders with RPL19           About GenesLikeMe

    2 Novoseek inferred disease relationships for RPL19 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    breast cancer 18.8 2 8095182 (1), 12727839 (1)
    tumors 0 2 8095182 (1), 19799608 (1)


    Export disorders for RPL19 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL19 gene, integrated from 10 sources (see all 73):
    (articles sorted by number of sources associating them with RPL19)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. High-level expression of the ribosomal protein L19 in human breast tumors that overexpress erbB-2. (PubMed id 8095182)1, 2, 9 Henry J.L.... King C.R. (Cancer Res. 1993)
    2. Human cDNAs encoding elongation factor 1 gamma and the ribosomal protein L19. (PubMed id 1598220)1, 2, 9 Kumabe T.... Yamamoto T. (Nucleic Acids Res. 1992)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome. (PubMed id 1577483)1, 3 Feo S....Fried M. (Genomics 1992)
    5. Identification of ribosomal protein L19 as a novel tumor antigen recognized by autologous cytotoxic T lymphocytes in lung adenocarcinoma. (PubMed id 19799608)1, 9 Kuroda K....Yasumoto K. (Cancer Sci. 2010)
    6. Ribosomal protein l19 is a prognostic marker for human prostate cancer. (PubMed id 16609016)1, 9 Bee A....Foster C.S. (Clin. Cancer Res. 2006)
    7. Expression of cholecystokinin in the duodenum of patients with coeliac disease: respective role of atrophy and lymphocytic infiltration. (PubMed id 12149109)1, 9 Deprez P.H....Geubel A. (Clin. Sci. 2002)
    8. The L19 ribosomal protein gene (RPL19): gene organization, chromosomal mapping, and novel promoter region. (PubMed id 7789970)1, 9 Davies B. and Fried M. (Genomics 1995)
    9. Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription. (PubMed id 24140708)1 Wu T....Zhang D.D. (amp 2014)
    10. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6143 HGNC: 10312 AceView: RPL19 Ensembl:ENSG00000108298 euGenes: HUgn6143
    ECgene: RPL19 Kegg: 6143 H-InvDB: RPL19

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPL19 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPL19 gene:
    Search GeneIP for patents involving RPL19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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