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RPL18A Gene

protein-coding   GIFtS: 61
GCID: GC19P017970

Ribosomal Protein L18a

  See RPL18A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein L18a1 2
60S Ribosomal Protein L18a1 2
Ribosomal Protein L18a-Like Protein1 2
L18A2

External Ids:    HGNC: 103111   Entrez Gene: 61422   Ensembl: ENSG000001056407   OMIM: 6041785   UniProtKB: Q025433   

Export aliases for RPL18A gene to outside databases

Previous GC identifers: GC12P103772 GC19P018362 GC19P017815 GC19P017831 GC19P017536


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL18A Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The
encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome
entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is
typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed
throughout the genome. (provided by RefSeq, Jul 2012)

GeneCards Summary for RPL18A Gene:
RPL18A (ribosomal protein L18a) is a protein-coding gene. Diseases associated with RPL18A include hepatitis c, and hepatitis c virus. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL18A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL18A gene promoter:
         STAT5B   Sp1   AP-1   MyoD   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL18A promoter sequence
   Search Chromatin IP Primers for RPL18A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL18A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.11

RPL18A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL18A gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P017970:  view genomic region     (about GC identifiers)

Start:
17,970,685 bp from pter      End:
17,974,962 bp from pter
Size:
4,278 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RL18A_HUMAN, Q02543 (See protein sequence)
Recommended Name: 60S ribosomal protein L18a  
Size: 176 amino acids; 20762 Da
Subunit: Binds IPO9 with high affinity
Sequence caution: Sequence=CAA56788.1; Type=Frameshift; Positions=65;
1 PDB 3D structure from and Proteopedia for RPL18A:
3J3B (3D)    

Explore the universe of human proteins at neXtProt for RPL18A: NX_Q02543

Explore proteomics data for RPL18A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys11, Lys21, Lys41, Lys70, Lys76, Lys136, Lys143, Lys151, Lys170
  • Modification sites at PhosphoSitePlus

  • See RPL18A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000971.1  
    ENSEMBL proteins: 
     ENSP00000222247   ENSP00000471584   ENSP00000471360   ENSP00000473155   ENSP00000471748  
    Reactome Protein details: Q02543

    RPL18A Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for RPL18A

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    3 InterPro protein domains:
     IPR021138 Ribosomal_L18a/L20_eukaryotes
     IPR028877 50S_L18Ae/Ribosomal_L18a/L20
     IPR023573 Ribosomal_L18a/LX

    Graphical View of Domain Structure for InterPro Entry Q02543

    ProtoNet protein and cluster: Q02543

    1 Blocks protein domain: IPB002670 Ribosomal L18ae protein

    UniProtKB/Swiss-Prot: RL18A_HUMAN, Q02543
    Similarity: Belongs to the ribosomal protein L18Ae family


    Find genes that share domains with RPL18A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL18A:
    60S ribosomal protein L18A

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS9582194
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RPL18A           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for RPL18A:
     Decreased cell number, increas  Decreased viability of wild-ty  Nuclear 60S biogenesis defects  Nucleolar pre-40S maturation d 
     S arrest 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL18A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL18A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL18A

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL18A:
    hsa-mir-744-5p (MIRT037405), hsa-let-7c-5p (MIRT051763), hsa-mir-181b-5p (MIRT047248), hsa-mir-106b-5p (MIRT044376), hsa-mir-423-5p (MIRT038096), hsa-mir-92a-3p (MIRT049166), hsa-mir-503-5p (MIRT041123), hsa-let-7b-5p (MIRT052313), hsa-mir-421 (MIRT039363), hsa-mir-652-3p (MIRT039488), hsa-mir-301a-3p (MIRT044219), hsa-mir-149-5p (MIRT045556), hsa-mir-20a-5p (MIRT050561), hsa-mir-186-5p (MIRT044981)

    Block miRNA regulation of human, mouse, rat RPL18A using miScript Target Protectors
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL18A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325

    Find genes that share ontologies with RPL18A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL18A About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease


    Find genes that share SuperPaths with RPL18A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL18A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL18A
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPL18A (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL18A):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL18A
    Interactions:

        GeneGlobe Interaction Network for RPL18A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL18A (Q025432, 3 ENSP000002222474) via UniProtKB, MINT, STRING, and/or I2D (see all 598)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    Find genes that share ontologies with RPL18A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL18A (RL18A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPL18A gene: 
    NM_000980.3  

    Unigene Cluster for RPL18A:

    Ribosomal protein L18a
    Hs.337766  [show with all ESTs]
    Unigene Representative Sequence: BQ050118
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000222247(uc002nhp.2) ENST00000600147 ENST00000599898 ENST00000602216
    ENST00000597648 ENST00000599870 ENST00000600238
    miRNA
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    Inhib. RNA
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    Clone
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    Primer
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    OriGene qPCR primer pairs and template standards for RPL18A
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPL18A
      QuantiTect SYBR Green Assays in human, mouse, rat RPL18A
      QuantiFast Probe-based Assays in human, mouse, rat RPL18A

    Additional mRNA sequence: 

    AK222647.1 AK297323.1 AK297358.1 AK300809.1 AK311774.1 AY779046.1 BC007512.2 BC066319.1 
    BC071920.1 L05093.1 X80822.1 

    Selected DOTS entries (see all 67):

    DT.100729755  DT.91806807  DT.99953477  DT.100729745  DT.100729777  DT.100729776  DT.451333  DT.91968871 
    DT.91856750  DT.100856198  DT.121139960  DT.91668700  DT.91903236  DT.92003336  DT.100729769  DT.121431777 
    DT.91819008  DT.100729748  DT.121432177  DT.100729752  DT.91637683  DT.121432220  DT.121431821  DT.121140092 

    Selected AceView cDNA sequences (see all 2297):

    CB148788 BM558540 AU143122 CB135763 BM697251 BF691755 AV726159 AA339943 
    CD610114 BM451583 BM558671 N46931 BF726091 AV709758 BQ446708 AW843360 
    AA344710 BU527955 CB148317 N20964 BM686670 H59123 BQ941229 H43519 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL18A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGTGGAGG
    RPL18A Expression
    About this image


    RPL18A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 17) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    RPL18A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL18A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.337766
        Custom PCR Arrays for RPL18A
    Primer
    Products:
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    QuantiFast Probe-based Assays in human, mouse, rat RPL18A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL18A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL18A gene from Selected species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl18a1 , 5 ribosomal protein L18A1, 5 88.83(n)1
    99.43(a)1
      8 (34.38 cM)5
    768081  NM_029751.41  NP_084027.11 
     708947225 
    chicken
    (Gallus gallus)
    Aves RPL18A1 ribosomal protein L18a 81.23(n)
    95.98(a)
      417823  XM_416064.4  XP_416064.3 
    lizard
    (Anolis carolinensis)
    Reptilia RPL18A6
    ribosomal protein L18a
    99(a)
    1 ↔ 1
    5(50519772-50527795)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.83692 Xenopus laevis, Similar to ribosomal protein L18a, clone IMAGE5571479, mRNA, partial cds less 81.62(n)    BC042256.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc565462 similar to 60S ribosomal protein L18a 79.22(n)   394035  BC049045.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL18A1 , 3 protein biosynthesis structural
    constituent of ribosome less3
    Ribosomal protein L18A1
    68(a)3
    71.59(n)1
    68.75(a)1
      54C33
    369851  NM_079050.21  NP_523774.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-203 ribosomal protein 62(a)   IV(4749375-4749965)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL20B(YOR312C)4
    RPL20A1
    Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein less4
    RPL20A1
    55.75(n)1
    56.55(a)1
      15(901194-900250)4
    8552831  NP_013969.31  8544894 
     NP_014957.24 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G299651 AT1G29965 54.9(n)
    53.53(a)
      839875  NM_179398.1  NP_849729.1 
    rice
    (Oryza sativa)
    Liliopsida Os.249562 Transcribed sequence with weak similarity to protein refNP_180995.1 (A.thaliana) 60S ribosomal protein L18A [Arabidopsis thaliana] less 75.44(n)    CA763169.1 


    ENSEMBL Gene Tree for RPL18A (if available)
    TreeFam Gene Tree for RPL18A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL18A gene

    Find genes that share paralogs with RPL18A           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RPL18A (see all 20)
    PGOHUM00000248436 PGOHUM00000247885 PGOHUM00000246917 PGOHUM00000237376 PGOHUM00000237427


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL18A (see all 72)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1426334721,2
    --17968871(+) GATCAC/TGCTGC 1 -- us2k10--------
    rs1817721401,2
    --17968876(+) CGCTGC/TTGCAC 1 -- us2k10--------
    rs1459467651,2
    --17968988(+) GTAACA/GTATTT 1 -- us2k10--------
    rs1118376781,2
    C--17969069(+) CGGTGA/GCTTAC 1 -- us2k10--------
    rs713321161,2
    C,F--17969245(+) GGCGGC/GAGAAT 1 -- us2k12Minor allele frequency- G:0.00NA 4
    rs1868538941,2
    --17969294(+) ATAGCA/GCCACT 1 -- us2k10--------
    rs1116576671,2
    C,F--17969331(+) GACTCG/AGTCTC 1 -- us2k11Minor allele frequency- A:0.00CSA 1
    rs1905481861,2
    --17969355(+) AAAAGA/GAAAGA 1 -- us2k10--------
    rs1827990971,2
    --17969399(+) ACAAAA/GCCAGA 1 -- us2k10--------
    rs1429268211,2
    --17969422(+) GAAATA/GCAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL18A (17970685 - 17974962 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RPL18A:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3766n71CNV Loss21882294
    nsv911219CNV Loss21882294
    nsv911214CNV Loss21882294
    nsv911225CNV Loss21882294
    nsv911209CNV Loss21882294
    nsv833772CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604178    OMIM disorders: --

    3 diseases for RPL18A:    
    About MalaCards
    hepatitis c    hepatitis c virus    hepatitis


    Find genes that share disorders with RPL18A           About GenesLikeMe


    Export disorders for RPL18A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL18A gene, integrated from 10 sources (see all 56):
    (articles sorted by number of sources associating them with RPL18A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    4. Importins fulfill a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. (PubMed id 11823430)1, 2 Jaekel S.... Goerlich D. (EMBO J. 2002)
    5. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    6. Human ribosomal protein L18a interacts with hepatitis C virus internal ribosome entry site. (PubMed id 16195786)1, 9 Dhar D.... Das S. (Arch. Virol. 2006)
    7. The leucine zipper of c-Jun binds to ribosomal protein L18a: a role in Jun protein regulation? (PubMed id 7662174)1, 9 Gramatikoff K....Georgiev O. (Biol. Chem. Hoppe-Seyler 1995)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    10. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6142 HGNC: 10311 AceView: RPL18A Ensembl:ENSG00000105640 euGenes: HUgn6142
    ECgene: RPL18A Kegg: 6142 H-InvDB: RPL18A

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPL18A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RPL18A gene:
    Search GeneIP for patents involving RPL18A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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