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Aliases for RPL17-C18orf32 Gene

Aliases for RPL17-C18orf32 Gene

  • RPL17-C18orf32 Readthrough 2 3 5

External Ids for RPL17-C18orf32 Gene

Previous GeneCards Identifiers for RPL17-C18orf32 Gene

  • GC18M047009

Summaries for RPL17-C18orf32 Gene

Entrez Gene Summary for RPL17-C18orf32 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RPL17 (ribosomal protein L17) and C18orf32 (chromosome 18 open reading frame 32) genes. Alternative splicing results in multiple transcript variants. The encoded isoforms share sequence identity with the RPL17 protein, but they include frameshifted C-terminal regions derived from the downstream gene exons. [provided by RefSeq, Dec 2010]

GeneCards Summary for RPL17-C18orf32 Gene

RPL17-C18orf32 (RPL17-C18orf32 Readthrough) is a Protein Coding gene. Among its related pathways are Viral mRNA Translation. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome. An important paralog of this gene is RPL17.

Additional gene information for RPL17-C18orf32 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPL17-C18orf32 Gene

Genomics for RPL17-C18orf32 Gene

Regulatory Elements for RPL17-C18orf32 Gene

Enhancers for RPL17-C18orf32 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18H049520 0.9 ENCODE 11.1 -28.7 -28687 0.9 ZSCAN4 INSM2 KLF17 FEZF1 ZEB1 GLIS2 ZNF366 ZNF416 EGR2 ZNF362 MBD1 LIPG RPL17-C18orf32 SNORD58A SNORD58C DYM C18orf32 LOC101928144 GC18M049549
GH18H049465 0.6 ENCODE 11.2 +27.1 27070 0.7 ZFP37 FEZF1 ZNF501 ZIC2 OSR2 ZNF664 GLIS1 ZNF24 ZNF600 PRDM1 SNORD58C RPL17-C18orf32 SNORD58A DYM PRR13P4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RPL17-C18orf32 on UCSC Golden Path with GeneCards custom track

Promoters for RPL17-C18orf32 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000103216 565 1601 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF302 ZNF143

Genomic Locations for RPL17-C18orf32 Gene

Genomic Locations for RPL17-C18orf32 Gene
11,388 bases
Minus strand

Genomic View for RPL17-C18orf32 Gene

Genes around RPL17-C18orf32 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPL17-C18orf32 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPL17-C18orf32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPL17-C18orf32 Gene

Proteins for RPL17-C18orf32 Gene

  • Protein details for RPL17-C18orf32 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    RPL17-C18orf32 readthrough
    Protein Accession:

    Protein attributes for RPL17-C18orf32 Gene

    190 amino acids
    Molecular mass:
    22070 Da
    Quaternary structure:
    No Data Available
  • Protein details for RPL17-C18orf32 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein RPL17-C18orf32
    Protein Accession:

    Protein attributes for RPL17-C18orf32 Gene

    228 amino acids
    Molecular mass:
    26373 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RPL17-C18orf32 Gene

Protein Expression for RPL17-C18orf32 Gene

Post-translational modifications for RPL17-C18orf32 Gene

No Post-translational modifications

Other Protein References for RPL17-C18orf32 Gene

No data available for DME Specific Peptides for RPL17-C18orf32 Gene

Domains & Families for RPL17-C18orf32 Gene

Gene Families for RPL17-C18orf32 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RPL17-C18orf32 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RPL17-C18orf32: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RPL17-C18orf32 Gene

Function for RPL17-C18orf32 Gene

Phenotypes for RPL17-C18orf32 Gene

GenomeRNAi human phenotypes for RPL17-C18orf32:
genes like me logo Genes that share phenotypes with RPL17-C18orf32: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPL17-C18orf32 Gene

Localization for RPL17-C18orf32 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Endoplasmic reticulum (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RPL17-C18orf32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005840 ribosome IEA --
GO:0015934 large ribosomal subunit IEA --
GO:0030529 intracellular ribonucleoprotein complex IEA --
genes like me logo Genes that share ontologies with RPL17-C18orf32: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for RPL17-C18orf32 Gene

Pathways & Interactions for RPL17-C18orf32 Gene

SuperPathways for RPL17-C18orf32 Gene

SuperPathway Contained pathways
1 Viral mRNA Translation
genes like me logo Genes that share pathways with RPL17-C18orf32: view

Pathways by source for RPL17-C18orf32 Gene

1 KEGG pathway for RPL17-C18orf32 Gene

Interacting Proteins for RPL17-C18orf32 Gene

Gene Ontology (GO) - Biological Process for RPL17-C18orf32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation IEA --
genes like me logo Genes that share ontologies with RPL17-C18orf32: view

No data available for SIGNOR curated interactions for RPL17-C18orf32 Gene

Drugs & Compounds for RPL17-C18orf32 Gene

No Compound Related Data Available

Transcripts for RPL17-C18orf32 Gene

mRNA/cDNA for RPL17-C18orf32 Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RPL17-C18orf32 Gene

No ASD Table

Relevant External Links for RPL17-C18orf32 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RPL17-C18orf32 Gene

Protein differential expression in normal tissues from HIPED for RPL17-C18orf32 Gene

This gene is overexpressed in Tlymphocyte (10.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for RPL17-C18orf32 Gene

Protein tissue co-expression partners for RPL17-C18orf32 Gene

Evidence on tissue expression from TISSUES for RPL17-C18orf32 Gene

  • Lung(4.7)
  • Nervous system(4.7)
  • Eye(4.4)
  • Skin(4.4)
  • Liver(4.3)
  • Intestine(4.1)
  • Kidney(4.1)
  • Muscle(4)
  • Pancreas(3.9)
  • Heart(3.7)
  • Stomach(3.5)
  • Blood(3.2)
  • Bone(3)
  • Spleen(2.4)
  • Thyroid gland(2.1)
  • Adrenal gland(2)
  • Lymph node(2)

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPL17-C18orf32 Gene

Orthologs for RPL17-C18orf32 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RPL17-C18orf32 Gene

Organism Taxonomy Gene Similarity Type Details
(Monodelphis domestica)
Mammalia -- 34
  • 92 (a)
(Mus musculus)
Mammalia Rpl17 34
  • 92 (a)
Gm10362 33 16
  • 89.22 (n)
Gm6133 34
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 92 (a)
(Canis familiaris)
Mammalia -- 34
  • 91 (a)
-- 34
  • 72 (a)
(Bos Taurus)
Mammalia -- 34
  • 89 (a)
-- 34
  • 86 (a)
-- 34
  • 84 (a)
(Rattus norvegicus)
Mammalia LOC499522 33
  • 85.88 (n)
(Gallus gallus)
Aves -- 34
  • 92 (a)
-- 34
  • 92 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rpl17 33
  • 78.34 (n)
(Danio rerio)
Actinopterygii rpl17 33 34
  • 77.59 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta RL17_ANOGA 33
  • 66.27 (n)
fruit fly
(Drosophila melanogaster)
Insecta RpL17 33 34
  • 64.76 (n)
(Caenorhabditis elegans)
Secernentea rpl-17 33 34
  • 60.62 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPL17B 34
  • 52 (a)
RPL17A 34
  • 52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4564 34
  • 73 (a)
Species where no ortholog for RPL17-C18orf32 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPL17-C18orf32 Gene

Gene Tree for RPL17-C18orf32 (if available)
Gene Tree for RPL17-C18orf32 (if available)

Paralogs for RPL17-C18orf32 Gene

Paralogs for RPL17-C18orf32 Gene Pseudogenes for RPL17-C18orf32 Gene

genes like me logo Genes that share paralogs with RPL17-C18orf32: view

Variants for RPL17-C18orf32 Gene

Sequence variations from dbSNP and Humsavar for RPL17-C18orf32 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs1000167975 -- 49,483,504(+) AAAAC(C/T)TGTCC intron-variant
rs1000261753 -- 49,488,623(+) TGGAG(A/G)ACTTC intron-variant, upstream-variant-2KB
rs1000314483 -- 49,488,255(+) TTTTT(A/T)ACAGA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1000460489 -- 49,486,700(+) GACAG(C/T)TAAAG intron-variant, upstream-variant-2KB
rs1000599285 -- 49,487,575(+) GCTAT(C/T)AGTTT intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RPL17-C18orf32 Gene

Variant ID Type Subtype PubMed ID
nsv978629 CNV duplication 23825009
nsv2295 CNV insertion 18451855
nsv2294 CNV deletion 18451855
nsv1160523 CNV deletion 26073780
nsv1065279 CNV gain 25217958

Variation tolerance for RPL17-C18orf32 Gene

Residual Variation Intolerance Score: 52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.18; 39.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RPL17-C18orf32 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPL17-C18orf32 Gene

Disorders for RPL17-C18orf32 Gene

Relevant External Links for RPL17-C18orf32

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RPL17-C18orf32 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RPL17-C18orf32 Gene

Publications for RPL17-C18orf32 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 60

Products for RPL17-C18orf32 Gene

Sources for RPL17-C18orf32 Gene

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