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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPL13A Gene

protein-coding   GIFtS: 60
GCID: GC19P049991

ribosomal protein L13a

(Previous name: tissue specific transplantation antigen 1 )
(Previous symbol: TSTA1)
 Explore 3 diseases affiliated with
RPL13A via our new
 Human Malady Compendium 
Biological research products
for RPL13A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ribosomal Protein L13a1 2
L13A1 2
TSTA11 2
Tissue Specific Transplantation Antigen 11 2
23 KDa Highly Basic Protein2 3
60S Ribosomal Protein L13a2

External Ids:    HGNC: 103041   Entrez Gene: 235212   Ensembl: ENSG000001425417   UniProtKB: P404293   

Export aliases for RPL13A gene to outside databases

Previous GC identifers: GC19P050649 GC19P050359 GC19P054666 GC19P054682


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RPL13A:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene
encodes a member of the L13P family of ribosomal proteins that is a component of the 60S subunit. The encoded protein
also plays a role in the repression of inflammatory genes as a component of the IFN-gamma-activated inhibitor of
translation (GAIT) complex. This gene is co-transcribed with the small nucleolar RNA genes U32, U33, U34, and U35,
which are located in the second, fourth, fifth, and sixth introns, respectively. As is typical for genes encoding
ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by
RefSeq, Jul 2012)

UniProtKB/Swiss-Prot: RL13A_HUMAN, P40429
Function: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal
functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates
interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma
activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which
binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and
suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site
and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA

Gene Wiki entry for RPL13A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPL13A gene promoter:
         AhR   TBP   STAT5A   AP-4   Tal-1beta   FOXL1   Arnt   c-Ets-1   E47   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL13A promoter sequence
   Search SABiosciences Chromatin IP Primers for RPL13A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPL13A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.3

RPL13A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL13A gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P049991:  view genomic region     (about GC identifiers)

Start:
49,990,811 bp from pter      End:
49,995,565 bp from pter
Size:
4,755 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RL13A_HUMAN, P40429 (See protein sequence)
Recommended Name: 60S ribosomal protein L13a  
Size: 203 amino acids; 23577 Da
Subunit: Component of the 60S ribosome. Component of the GAIT complex. Interacts with EIF4G1
Subcellular location: Cytoplasm (Probable)
Secondary accessions: A8K505

Explore the universe of human proteins at neXtProt for RPL13A: NX_P40429

Post-translational modifications:

  • Phosphorylation at Ser-77 upon interferon-gamma treatment in monocytes involves a DAPK1-DAPK3 kinase cascade and is
  • causing release from the ribosome, association with the GAIT complex and subsequent involvement in
    transcript-selective translation inhibition1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P40429

  • RPL13A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001257420.1  NP_036555.1  

    ENSEMBL proteins: 
     ENSP00000375730  
    Reactome Protein details: P40429
    Human Recombinant Protein Products: 
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    Uscn Proteins for RPL13A

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0015934large ribosomal subunit TAS10580157
    GO:0022625cytosolic large ribosomal subunit IDA12962325
    GO:0030529ribonucleoprotein complex IDA18809582


    RPL13A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RPL13A for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR023563 Ribosomal_L13_CS
     IPR005822 Ribosomal_L13
     IPR005755 Ribosomal_L13_euk/arc
     IPR023564 Ribosomal_L13_dom

    Graphical View of Domain Structure for InterPro Entry P40429

    ProtoNet protein and cluster: P40429

    1 Blocks protein family: IPB005822 Ribosomal protein L13

    UniProtKB/Swiss-Prot: RL13A_HUMAN, P40429
    Similarity: Belongs to the ribosomal protein L13P family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RL13A_HUMAN, P40429
    Function: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal
    functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates
    interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma
    activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which
    binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and
    suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site
    and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA

         Genatlas biochemistry entry for RPL13A:
    60S ribosomal protein L13-2

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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome NAS12962325


    RPL13A for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for RPL13A:
     Decreased G3BP1 protein expres  Decreased TP53 protein express  Decreased viability of wild-ty  Increased S DNA content 
     S arrest 

    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rpl13a):
     no phenotypic analysis 

    RPL13A for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    Viral Protein Synthesis1.00
    Cytoplasmic Ribosomal Proteins0.86
    Viral mRNA Translation1.00
    CFTR translational fidelity (class I mutations)0.83
    Influenza Viral RNA Transcription and Replication1.00
    SMG6 Cleaves mRNA with Premature Termination Codon0.80
    Synthesis of nascent polypeptide containing signal sequence1.00
    L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Metabolism of mRNA
    Metabolism of mRNA1.00
    Metabolism of RNA0.92
    3Translational Control
    Translational Control1.00
    4Disease
    Disease1.00
    5Generic Transcription Pathway
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for RPL13A
        Translational Control

    1 GeneGo (Thomson Reuters) Pathway for RPL13A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL13A 
        Cytoplasmic Ribosomal Proteins

    5/28        Reactome Pathways for RPL13A (see all 28)
        Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane
    Eukaryotic Translation Initiation


    1         Kegg Pathway  (Kegg details for RPL13A):
        Ribosome


    RPL13A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RPL13A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/485 Interacting proteins for RPL13A (P404292, 3 ENSP000003757304) via UniProtKB, MINT, STRING, and/or I2D (see all 485)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    RPL13A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RPL13A

    3 DrugBank Compounds for RPL13A    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about RPL13A / RL13A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPL13A gene (2 alternative transcripts): 
    NM_001270491.1  NM_012423.3  

    Unigene Cluster for RPL13A:

    Ribosomal protein L13a
    Hs.523185  [show with all ESTs]
    Unigene Representative Sequence: BG121812
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000391857(uc002pny.3 uc002pnz.3) ENST00000472481 ENST00000484279
    ENST00000488946 ENST00000479992 ENST00000486930 ENST00000476268 ENST00000467825
    ENST00000477613 ENST00000474171 ENST00000468655 ENST00000476300

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    Additional cDNA sequence: 

    AB082924.1 AK130605.1 AK222747.1 AK291120.1 AK297859.1 BC000514.2 BC000847.1 BC001675.2 
    BC001836.2 BC004900.2 BC013230.1 BC032107.2 BC062537.1 BC065236.1 BC070223.1 BC071929.1 
    BC105605.1 NR_073024.1 X56932.1 

    24/146 DOTS entries (see all 146):

    DT.87003128  DT.75124041  DT.87011808  DT.100764199  DT.100856870  DT.100852855  DT.121499556  DT.100853775 
    DT.95231396  DT.95361948  DT.100866872  DT.95221684  DT.100723072  DT.97869220  DT.102841617  DT.100723049 
    DT.95167200  DT.95221934  DT.100859565  DT.91783221  DT.75143508  DT.121499536  DT.100043405  DT.100864593 

    24/55 AceView cDNA sequences (see all 55):

    CR625138 AK130605 CR591301 CR622697 CR596601 CR615101 NR_000018 BC071929 
    CR599383 CR618182 CR601809 CR623949 BC065236 BC001675 CR608676 CR595200 
    BC070223 BC000847 CR620187 CR619845 CR613016 AK056837 CR607352 CR606179 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for RPL13A (see all 14)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d
    SP1:                    -                 -           -           -                                                         
    SP2:                          -           -           -           -                                                         
    SP3:              -     -     -           -           -           -                                                         
    SP4:              -     -     -           -           -           -                                                         
    SP5:                    -     -           -           -           -                                                         


    ECgene alternative splicing isoforms for RPL13A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPL13A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGCTACGGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RPL13A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPL13A

    SOURCE GeneReport for Unigene cluster: Hs.523185
        SABiosciences Custom PCR Arrays for RPL13A
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL13A gene from 9/37 species (see all 37)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl13a1 , 5 ribosomal protein L13A1, 5 88.01(n)1
    95.57(a)1
      7 (29.14 cM)5
    221211  NM_009438.51  NP_033464.21 
     451255585 
    lizard
    (Anolis carolinensis)
    Reptilia RPL13A6
    --
    91(a)
    1 ↔ 1
    GL343355.1(503203-511103)
    African clawed frog
    (Xenopus laevis)
    Amphibia rpl13a-prov2 ribosomal protein L13a 81.34(n)    BC043976.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Gstp12 Danio rerio mRNA similar to ribosomal protein L13a more 77.11(n)    BC047855.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG14753
    RpL13A1
    protein biosynthesis structural constituent
    of more3
    Ribosomal protein L13A1
    58(a)3
    63.95(n)1
    58.16(a)1
      406871  NM_141303.21  NP_649560.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-161 , 3 L13P family ribosomal protein3
    Protein RPL-161
    54(a)3
    59.15(n)1
    54.36(a)1
      III(3574411-3575570)3
    1754551  NM_065320.61  NP_497721.11 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_AER367C1 60S ribosomal protein L16 57.94(n)
    57.07(a)
      4621439  NM_210577.1  NP_985223.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G071101 60S ribosomal protein L13a-1 61.23(n)
    61.58(a)
      819897  NM_001035577.1  NP_001030654.1 
    rice
    (Oryza sativa)
    Liliopsida AK063806.12   -- 75.64(n)    AK063806.1 


    ENSEMBL Gene Tree for RPL13A (if available)
    TreeFam Gene Tree for RPL13A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RPL13A gene
    1 SIMAP similar gene for RPL13A using alignment to 5 protein entries:     RL13A_HUMAN (see all proteins):
    RPL13a

    RPL13A for paralogs           About GeneDecksing


    5/32 Pseudogenes.org Pseudogenes for RPL13A (see all 32)
    PGOHUM00000238477 PGOHUM00000238624 PGOHUM00000242600 PGOHUM00000239296 PGOHUM00000239392


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/190 NCBI SNPs in RPL13A are shown (see all 190    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1506401941,2
    --49990037(+) ACTGAC/GGCCCA 3 -- us2k10--------
    rs18792661,2
    C,F,A,H,--49990060(-) CTGGAG/CAAACC 3 -- us2k124Minor allele frequency- C:0.33EA NA NS WA CSA EU 2017
    rs1398176931,2
    --49990139(+) TCACGC/TCGGTA 3 -- us2k10--------
    rs722707621,2
    C,--49990251(+) ATATA-/ATTATAT 3 -- us2k10--------
    rs1839908411,2
    --49990350(+) GGAAGG/TGGAGG 3 -- us2k10--------
    rs1887211591,2
    --49990407(+) CAGCGA/GGACCC 3 -- us2k10--------
    rs735806591,2
    C,--49990410(+) CGAGAC/TCCTGT 3 -- us2k10--------
    rs766876111,2
    C,F,--49990465(+) CTGGCG/AGGTCT 3 -- us2k12Minor allele frequency- A:0.04NA NS 256
    rs735806611,2
    C,--49990523(+) GAAGGG/AGTAAT 3 -- us2k11Minor allele frequency- A:0.50WA 2
    rs72464971,2
    C,F,--49990618(+) GCCGTG/ACCCCA 3 -- us2k11Minor allele frequency- A:0.05WA 118

    HapMap Linkage Disequilibrium report for RPL13A (49990811 - 49995565 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for RPL13A
         3 CNVs: 5111 5110 32261

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RPL13A for disorders           About GeneDecksing

    3 diseases for RPL13A:    About MalaCards
    treacher collins syndrome    gingivitis    malaria

    Human Genome Epidemiology (HuGE) Navigator: RPL13A (3 documents)

    Export disorders for RPL13A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPL13A gene, integrated from 9 sources (see all 58):
    (articles sorted by number of sources associating them with RPL13A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome. (PubMed id 10580157)1, 2, 9 Higa S.... Kenmochi N. (1999)
    2. Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation. (PubMed id 17921318)1, 2, 9 Chaudhuri S....Mazumder B. (2007)
    3. DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression. (PubMed id 18995835)1, 2, 9 Mukhopadhyay R....Fox P.L. (2008)
    4. L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational control. (PubMed id 17218275)1, 2, 9 Kapasi P....Mazumder B. (2007)
    5. Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. (PubMed id 14567916)1, 2, 9 Mazumder B....Fox P.L. (2003)
    6. Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation. (PubMed id 15479637)1, 2 Sampath P....Fox P.L. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. (PubMed id 12962325)1, 2 Odintsova T.I....Karpova G.G. (2003)
    10. Conservation of a 23-kDa human transplantation antigen in mammalian species. (PubMed id 1282492)1, 2 Price S.R....Vaughan M. (1992)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23521 HGNC: 10304 AceView: RPL13A Ensembl:ENSG00000142541 euGenes: HUgn23521
    ECgene: RPL13A Kegg: 23521 H-InvDB: RPL13A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPL13A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPL13A gene:
    Search GeneIP for patents involving RPL13A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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