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RPL13 Gene

protein-coding   GIFtS: 64
GCID: GC16P089669

Ribosomal Protein L13

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein L131 2     60S Ribosomal Protein L132
BBC12 3 5     D16S444E2
Breast Basic Conserved Protein 12 3     L132
D16S44E2 5     OK/SW-cl.462

External Ids:    HGNC: 103031   Entrez Gene: 61372   Ensembl: ENSG000001675267   OMIM: 1137035   UniProtKB: P263733   

Export aliases for RPL13 gene to outside databases

Previous GC identifers: GC16P081509 GC16P090614 GC16P089330 GC16P089370 GC16P088154 GC16P089630 GC16P089631 GC16P075322 GC16P089633 GC16P089637 GC16P089650 GC16P089659


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL13 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13E family
of ribosomal proteins. It is located in the cytoplasm. This gene is expressed at significantly higher levels in
benign breast lesions than in breast carcinomas. Alternatively spliced transcript variants encoding distinct
isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2011)

GeneCards Summary for RPL13 Gene:
RPL13 (ribosomal protein L13) is a protein-coding gene. Diseases associated with RPL13 include skin atrophy, and treacher collins syndrome. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL13 gene promoter:
         MEF-2A   RFX1   Olf-1   aMEF-2   LCR-F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL13 promoter sequence
   Search Chromatin IP Primers for RPL13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.3|17p11.2   Ensembl cytogenetic band:  16q24.3   HGNC cytogenetic band: 16q24.3

RPL13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL13 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P089669:  view genomic region     (about GC identifiers)

Start:
89,627,065 bp from pter      End:
89,630,950 bp from pter
Size:
3,886 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RL13_HUMAN, P26373 (See protein sequence)
Recommended Name: 60S ribosomal protein L13  
Size: 211 amino acids; 24261 Da
1 PDB 3D structure from and Proteopedia for RPL13:
3J3B (3D)    
Secondary accessions: B4DLX3 F5H1S2 Q3KQT8 Q567Q8 Q9BPX0
Alternative splicing: 2 isoforms:  P26373-1   P26373-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPL13: NX_P26373

Explore proteomics data for RPL13 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys105, Lys123, Lys145, Lys174, Lys177
  • Modification sites at PhosphoSitePlus

  • See RPL13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_000968.2  NP_001230059.1  NP_001230060.1  NP_150254.1  

    ENSEMBL proteins: 
     ENSP00000307889   ENSP00000457686   ENSP00000455009   ENSP00000457174   ENSP00000438959  
     ENSP00000464612   ENSP00000376811   ENSP00000462380  
    Reactome Protein details: P26373

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    2 InterPro protein domains:
     IPR018256 Ribosomal_L13e_CS
     IPR001380 Ribosomal_L13e

    Graphical View of Domain Structure for InterPro Entry P26373

    ProtoNet protein and cluster: P26373

    1 Blocks protein domain: IPB001380 Ribosomal protein L13e

    UniProtKB/Swiss-Prot: RL13_HUMAN, P26373
    Similarity: Belongs to the ribosomal protein L13e family


    RPL13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL13:
    60S ribosomal protein 13,underexpressed in hormone refractory prostate cancer

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS9582194
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding IPI17474147
    GO:0044822poly(A) RNA binding IDA--
         
    RPL13 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RPL13:
     Synthetic lethal with Ras 

    Animal Models:
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    hsa-mir-744-5p (MIRT037675), hsa-mir-615-3p (MIRT039784), hsa-mir-26a-5p (MIRT050197), hsa-mir-16-5p (MIRT031830)

    Block miRNA regulation of human, mouse, rat RPL13 using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion1
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----

    RPL13 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL13 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL13
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL13
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPL13 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL13):
        Ribosome


    RPL13 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL13
    Interactions:

        Search GeneGlobe Interaction Network for RPL13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL13 (P263731, 2, 3 ENSP000003078894) via UniProtKB, MINT, STRING, and/or I2D (see all 1173)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2BP678702, 3MINT-8253616 I2D: score=2 
    ENSG00000206406P678702, 3MINT-8253616 I2D: score=2 
    ENSG00000224398P678702, 3MINT-8253616 I2D: score=2 
    ENSG00000224774P678702, 3MINT-8253616 I2D: score=2 
    ENSG00000228875P678702, 3MINT-8253616 I2D: score=2 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL13 (RL13)

    2 PharmGKB related drug/compound annotations for RPL13 gene    About this table
    Drug/compound PharmGKB Annotation
    docetaxelCA  
    thalidomideCA  



    RPL13 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPL13 gene (4 alternative transcripts): 
    NM_000977.3  NM_001243130.1  NM_001243131.1  NM_033251.2  

    Unigene Cluster for RPL13:

    Ribosomal protein L13
    Hs.410817  [show with all ESTs]
    Unigene Representative Sequence: NM_033251
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311528(uc010vpj.2 uc002fnm.2 uc021tmt.1) ENST00000491523
    ENST00000563749(uc010cim.1) ENST00000484610 ENST00000563270 ENST00000567815
    ENST00000487034 ENST00000562879 ENST00000565571 ENST00000452368 ENST00000467736
    ENST00000393099(uc002fnn.2 uc002fno.2) ENST00000399461 ENST00000570149
    ENST00000472354
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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      QuantiFast Probe-based Assays in human, mouse, rat RPL13

    Additional mRNA sequence: 

    AB062392.1 AK025405.1 AK095954.1 AK127579.1 AK290893.1 AK297198.1 AK308545.1 BC000851.1 
    BC004954.1 BC007345.2 BC007563.1 BC007805.2 BC010994.2 BC013078.1 BC014167.2 BC020804.1 
    BC027463.1 BC063378.1 BC066320.1 BC093063.1 BC106058.1 X64707.1 

    Selected DOTS entries (see all 99):

    DT.92471567  DT.95160044  DT.100712240  DT.100712206  DT.95073155  DT.100863104  DT.100712232  DT.100045843 
    DT.95313626  DT.100045837  DT.100712210  DT.120727498  DT.100712233  DT.95160125  DT.100712237  DT.100712209 
    DT.87013686  DT.97864838  DT.120727512  DT.86996156  DT.100712211  DT.120916875  DT.100712228  DT.92471597 

    Selected AceView cDNA sequences (see all 52):

    CR591315 CR591773 CR596850 CR600363 CR611560 AB062392 CR617344 NM_033251 
    D28432 CR604073 NM_000977 CR612063 AK130964 CR603377 CR594319 CR622575 
    CR615258 BC007563 CR610213 BC004954 CR597153 BC007345 CR619298 BC010994 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RPL13 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c · 7d · 7e
    SP1:                                      -     -     -                 -                       -                                 
    SP2:                                                                    -                                                         
    SP3:                                                                                                                              
    SP4:                          -     -     -     -     -                 -                       -                                 
    SP5:                                                                    -                                                         


    ECgene alternative splicing isoforms for RPL13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCGTCCGGA
    RPL13 Expression
    About this image


    RPL13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 20) fully expand
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
    RPL13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.410817

    UniProtKB/Swiss-Prot: RL13_HUMAN, P26373
    Tissue specificity: Higher levels of expression in benign breast lesions than in carcinomas

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL13 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl131 , 5 ribosomal protein L131, 5 86.89(n)1
    98.1(a)1
      8 (72.05 cM)5
    2701061  NM_016738.51  NP_058018.21 
     1231023505 
    chicken
    (Gallus gallus)
    Aves RPL131 ribosomal protein L13 79.94(n)
    92.42(a)
      395849  NM_204999.1  NP_990330.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL136
    ribosomal protein L13
    92(a)
    1 ↔ 1
    GL343487.1(443248-451073)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX844624.12   -- 87.09(n)    BX844624.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rpl132 ribosomal protein L13 78.09(n)   378961  AF385081.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL131 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein L131
    62(a)3
    64.84(n)1
    63.68(a)1
      2 30F53
    343291  NM_001038802.21  NP_001033891.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-131 rpl-13 60.84(n)
    57.28(a)
      171949  NM_001025846.3  NP_001021017.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL13A(YDL082W)4
    RPL13B1
    Protein component of the large (60S) ribosomal subunit, more4
    RPL13B1
    51.68(n)1
    52.53(a)1
      4(308424-309388)4
    8551731  NP_013862.11  8514774 
     NP_010201.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G239001 AT5G23900 54.39(n)
    55.72(a)
      832455  NM_122295.3  NP_197778.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g05767001 Os03g0576700 56.22(n)
    58.21(a)
      4333306  NM_001057072.1  NP_001050537.1 


    ENSEMBL Gene Tree for RPL13 (if available)
    TreeFam Gene Tree for RPL13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL13 gene

    RPL13 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPL13 (see all 21)
    PGOHUM00000238345 PGOHUM00000239633 PGOHUM00000248271 PGOHUM00000247177 PGOHUM00000234431


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL13 (see all 264)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1907746521,2
    --89625070(+) AGTAGG/TTGGGA 3 -- us2k10--------
    rs1462074241,2
    --89625083(+) ACAGGC/TGCCTG 3 -- us2k10--------
    rs1478412911,2
    --89625096(+) ACCACA/GCCCGG 3 -- us2k10--------
    rs1830066291,2
    --89625143(+) CCATGC/TTAGCC 4 -- us2k10--------
    rs1865451861,2
    --89625171(+) CTGACC/TTCGTG 4 -- us2k10--------
    rs1469715081,2
    --89625180(+) TGATCC/TGCCTG 4 -- us2k10--------
    rs1388563941,2
    --89625201(+) CCAAAA/GTGCTG 4 -- us2k10--------
    rs676898541,2
    C,F--89625227(+) GCCAGC/AACGCC 4 -- us2k15Minor allele frequency- A:0.12NA EA 246
    rs1157250731,2
    F--89625260(+) TGAGAC/TGGAGG 4 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1914571771,2
    --89625303(+) GTGCAC/GTCTCG 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL13 (89627065 - 89630950 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RPL13 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2715169CNV Deletion23290073
    esv994856CNV Insertion20482838
    nsv509639CNV Insertion20534489
    dgv3010n71CNV Loss21882294
    dgv3009n71CNV Loss21882294
    nsv907357CNV Loss21882294
    nsv907405CNV Loss21882294
    dgv3008n71CNV Loss21882294
    dgv3011n71CNV Loss21882294
    nsv471118CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL13
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 113703    OMIM disorders: --

    9 diseases for RPL13:    
    About MalaCards
    skin atrophy    treacher collins syndrome    smith magenis syndrome    influenza
    schizophrenia    prostatitis    prostate cancer    breast cancer
    malaria

    1 disease from the University of Copenhagen DISEASES database for RPL13:
    Skin atrophy

    RPL13 for disorders           About GeneDecksing


    Export disorders for RPL13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL13 gene, integrated from 10 sources (see all 75):
    (articles sorted by number of sources associating them with RPL13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. A map of 75 human ribosomal protein genes. (PubMed id 9582194)1, 3 Kenmochi N.... Page D.C. (Genome Res. 1998)
    4. Isolation and characterization of a novel gene with differential expression in benign and malignant human breast tumours. (PubMed id 1301162)1, 2 Adams S.M....Varley J.M. (Hum. Mol. Genet. 1992)
    5. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    6. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    7. Profiling of Parkin-binding partners using tandem affinity purification. (PubMed id 24244333)1 Zanon A....Pichler I. (PLoS ONE 2013)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6137 HGNC: 10303 AceView: RPL13 Ensembl:ENSG00000167526 euGenes: HUgn6137
    ECgene: RPL13 Kegg: 6137 H-InvDB: RPL13

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RPL13 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RPL13 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPL13 gene:
    Search GeneIP for patents involving RPL13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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