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RPL12 Gene

protein-coding   GIFtS: 63
GCID: GC09M130209

Ribosomal Protein L12

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein L121 2
60S Ribosomal Protein L122
L122

External Ids:    HGNC: 103021   Entrez Gene: 61362   Ensembl: ENSG000001979587   OMIM: 1804755   UniProtKB: P300503   

Export aliases for RPL12 gene to outside databases

Previous GC identifers: GC09M121324 GC09M121856 GC09M123663 GC09M125586 GC09M127289 GC09M129250 GC09M099825


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL12 Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family
of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is
co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding
ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. (provided
by RefSeq, Jul 2008)

GeneCards Summary for RPL12 Gene:
RPL12 (ribosomal protein L12) is a protein-coding gene. Diseases associated with RPL12 include treacher collins syndrome, and cleft lip. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

UniProtKB/Swiss-Prot: RL12_HUMAN, P30050
Function: Binds directly to 26S ribosomal RNA (By similarity)

Gene Wiki entry for RPL12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL12 gene promoter:
         Lmo2   AP-4   NF-E2 p45   LCR-F1   AREB6   FAC1   E2F-1   E2F   NF-E2   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL12 promoter sequence
   Search Chromatin IP Primers for RPL12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34   Ensembl cytogenetic band:  9q33.3   HGNC cytogenetic band: 9q34

RPL12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL12 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M130209:  view genomic region     (about GC identifiers)

Start:
130,209,953 bp from pter      End:
130,213,711 bp from pter
Size:
3,759 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RL12_HUMAN, P30050 (See protein sequence)
Recommended Name: 60S ribosomal protein L12  
Size: 165 amino acids; 17819 Da
1 PDB 3D structure from and Proteopedia for RPL12:
3J3B (3D)    
Secondary accessions: Q5VVV2 Q6PB27
Alternative splicing: 2 isoforms:  P30050-1   P30050-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPL12: NX_P30050

Explore proteomics data for RPL12 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys48, Lys61, Lys83, Lys99, Lys130
  • Modification sites at PhosphoSitePlus

  • See RPL12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000967.1  
    ENSEMBL proteins: 
     ENSP00000354739   ENSP00000441179  
    Reactome Protein details: P30050

    RPL12 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for RPL12


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    4 InterPro protein domains:
     IPR020783 Ribosomal_L11_C
     IPR020784 Ribosomal_L11_N
     IPR020785 Ribosomal_L11_CS
     IPR000911 Ribosomal_L11/L12

    Graphical View of Domain Structure for InterPro Entry P30050

    ProtoNet protein and cluster: P30050

    1 Blocks protein domain: IPB000911 Ribosomal protein L11

    UniProtKB/Swiss-Prot: RL12_HUMAN, P30050
    Similarity: Belongs to the ribosomal protein L11P family


    RPL12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RL12_HUMAN, P30050
    Function: Binds directly to 26S ribosomal RNA (By similarity)

         Genatlas biochemistry entry for RPL12:
    60S ribosomal protein L12

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0005515protein binding IPI--
    GO:0044822poly(A) RNA binding IDA--
         
    RPL12 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RPL12:
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Nuclear 60S biogenesis defects 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL12
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL12

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL12:
    hsa-let-7b-5p (MIRT051997), hsa-mir-218-5p (MIRT046988), hsa-mir-222-3p (MIRT046650), hsa-mir-193b-3p (MIRT041418), hsa-mir-16-5p (MIRT031402), hsa-let-7e-5p (MIRT051475), hsa-let-7g-5p (MIRT046558)

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL12


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    chloroplast2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325
    GO:0070062extracellular vesicular exosome IDA--

    RPL12 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL12 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL12
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL12
        Cytoplasmic Ribosomal Proteins


    Selected Reactome Pathways for RPL12 (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL12):
        Ribosome


    RPL12 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL12
    Interactions:

        Search GeneGlobe Interaction Network for RPL12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL12 (P300501, 2, 3 ENSP000003547394) via UniProtKB, MINT, STRING, and/or I2D (see all 1090)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL8P629172, 3, ENSP000002625844MINT-6542674 MINT-7945693 MINT-6489539 MINT-6488791 I2D: score=6 STRING: ENSP00000262584
    RPS3P233962, 3, ENSP000002785724MINT-6542674 MINT-7945693 MINT-6489539 MINT-6488791 I2D: score=3 STRING: ENSP00000278572
    RPS2P158802, 3, ENSP000003418854MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=3 STRING: ENSP00000341885
    RPL11P629132, 3, ENSP000003636764MINT-6542674 MINT-6489539 MINT-6488791 I2D: score=2 STRING: ENSP00000363676
    RPL13P263732, 3, ENSP000003078894MINT-6542674 MINT-7945693 MINT-6488791 I2D: score=2 STRING: ENSP00000307889
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL12 (RL12)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPL12 gene: 
    NM_000976.3  

    Unigene Cluster for RPL12:

    Ribosomal protein L12
    Hs.408054  [show with all ESTs]
    Unigene Representative Sequence: AK057602
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361436(uc004bqy.2 uc004bqz.2) ENST00000497825 ENST00000497322
    ENST00000483598 ENST00000536368
    miRNA
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    OriGene qPCR primer pairs and template standards for RPL12
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      QuantiTect SYBR Green Assays in human, mouse, rat RPL12
      QuantiFast Probe-based Assays in human, mouse, rat RPL12

    Additional mRNA sequence: 

    AB209471.1 AF037643.1 AK026526.1 AK057602.1 BC050644.1 BC059950.1 BC094831.1 BC105603.1 
    L06505.1 Y11159.1 

    Selected DOTS entries (see all 68):

    DT.91776054  DT.102840335  DT.85102005  DT.100761060  DT.91926813  DT.91820395  DT.100697094  DT.100697088 
    DT.87005955  DT.451137  DT.121170817  DT.97824072  DT.120834983  DT.121170814  DT.121170824  DT.40269548 
    DT.91796906  DT.100697087  DT.121170700  DT.91776065  DT.100055123  DT.120836783  DT.120974178  DT.121640399 

    Selected AceView cDNA sequences (see all 1708):

    BC059950 BM799319 BM820748 BM905754 AI818815 BE018763 BU500767 BM450985 
    AI969206 CR615987 F26763 BM768894 BM916082 AW610278 BM457231 BC050644 
    CA435775 BQ955917 BM759807 AW328390 BM764826 BU508374 BF183201 BE793176 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACATCATCGA
    RPL12 Expression
    About this image


    RPL12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Bone (Muscoskeletal System)
             Mandibular Condyle
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
    RPL12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.408054
        Custom PCR Arrays for RPL12
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL12 gene from Selected species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl121 , 5 ribosomal protein L121, 5 89.49(n)1
    99.39(a)1
      2 (22.09 cM)5
    2692611  NM_009076.31  NP_033102.21 
     329615595 
    chicken
    (Gallus gallus)
    Aves RPL121 ribosomal protein L12 81.21(n)
    95.15(a)
      417264  NM_001277679.1  NP_001264608.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL126
    ribosomal protein L12
    83(a)
    1 ↔ 1
    GL344004.1(24795-34417)
    African clawed frog
    (Xenopus laevis)
    Amphibia rpl12-prov2 ribosomal protein L12 88.49(n)    BC041240.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.246862 Danio rerio mRNA similar to ribosomal protein L12 (cDNA more 85.39(n)    BC049061.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL121 , 3 protein biosynthesis structural
    constituent of more3
    Ribosomal protein L121
    79(a)3
    70.12(n)1
    79.88(a)1
      60B73
    453291  NM_166655.11  NP_726412.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-121 , 3 Ribosomal protein L113
    rpl-121
    73(a)3
    69.11(n)1
    73.78(a)1
      IV(13239848-13240729)3
    1782791  NM_070141.61  NP_502542.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL12A1 RPL12A 66.67(n)
    71.17(a)
      856656   NP_010860.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G371901 AT2G37190 62.58(n)
    69.94(a)
      818295  NM_129275.2  NP_181256.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g05982001 Os04g0598200 64.04(n)
    67.88(a)
      4336856  NM_001060276.2  NP_001053741.1 


    ENSEMBL Gene Tree for RPL12 (if available)
    TreeFam Gene Tree for RPL12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL12 gene
    1 SIMAP similar gene for RPL12 using alignment to 1 protein entry:     RL12_HUMAN:
    cICK0721Q.2

    RPL12 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPL12 (see all 46)
    PGOHUM00000238568 PGOHUM00000238602 PGOHUM00000238633 PGOHUM00000238824 PGOHUM00000242210


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL12 (see all 41)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1505276661,2
    --130209512(+) TCATGA/GTAGTC 1 -- ds50010--------
    rs1395361111,2
    --130209513(+) CATGAC/TAGTCT 1 -- ds50010--------
    rs1869032491,2
    --130209565(+) TAATCC/TCAACA 1 -- ds50010--------
    rs1492401171,2
    --130209569(+) CCCAAC/TACTTT 1 -- ds50010--------
    rs1888588541,2
    --130209636(+) AAACCC/GTGTCT 1 -- ds50010--------
    rs22476871,2
    C,F,A--130209637(+) AACCCT/CGTCTT 1 -- ds50018Minor allele frequency- C:0.31NA WA EA NS 442
    rs1810859861,2
    --130209649(+) TAGCAC/TGTGCC 1 -- ds50010--------
    rs22476821,2
    C,F,A--130209700(+) CTTGAA/CTCTAG 1 -- ds50018Minor allele frequency- C:0.30NA WA EA NS 438
    rs1138328311,2
    C--130209705(+) ATCTAG/AAAGGC 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1444685231,2
    C--130209759(+) GGGCAA/GCGAGC 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for RPL12 (130209953 - 130213711 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RPL12: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL12
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 180475    OMIM disorders: --

    7 diseases for RPL12:    
    About MalaCards
    treacher collins syndrome    cleft lip    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    influenza    breast cancer    malaria


    RPL12 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPL12
    Human Genome Epidemiology (HuGE) Navigator: RPL12 (2 documents)

    Export disorders for RPL12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL12 gene, integrated from 10 sources (see all 78):
    (articles sorted by number of sources associating them with RPL12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The primary structure of human ribosomal protein L12. (PubMed id 8441690)1, 2, 3, 9 Chu W.... Burns D.K. (Nucleic Acids Res. 1993)
    2. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PubMed id 20583170)1, 4 Letra A....Vieira A.R. (Am. J. Med. Genet. A 2010)
    3. Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. (PubMed id 19834535)1, 4 Wheeler H.E....Kim S.K. (PLoS Genet. 2009)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11. (PubMed id 11809816)1, 9 Plafker S.M. and Macara I.G. (Mol. Cell. Biol. 2002)
    8. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)
    9. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    10. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6136 HGNC: 10302 AceView: RPL12 Ensembl:ENSG00000197958 euGenes: HUgn6136
    ECgene: RPL12 Kegg: 6136 H-InvDB: RPL12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPL12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RPL12 gene:
    Search GeneIP for patents involving RPL12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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