Aliases for RPL11 Gene
External Ids for RPL11 Gene
Previous GeneCards Identifiers for RPL11 Gene
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Dec 2010]
GeneCards Summary for RPL11 Gene
RPL11 (Ribosomal Protein L11) is a Protein Coding gene. Diseases associated with RPL11 include Diamond-Blackfan Anemia 7 and Diamond-Blackfan Anemia. Among its related pathways are Viral mRNA Translation and Validated targets of C-MYC transcriptional activation. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.
UniProtKB/Swiss-Prot for RPL11 Gene
Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity).