Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RPL10L Gene

protein-coding   GIFtS: 51
GCID: GC14M047120

Ribosomal Protein L10-Like

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Ribosomal Protein L10-Like1 2
60S Ribosomal Protein L10-Like2
RPL10_5_13582
Ribosomal Protein L10-Like Protein2

External Ids:    HGNC: 179761   Entrez Gene: 1408012   Ensembl: ENSG000001654967   UniProtKB: Q96L213   

Export aliases for RPL10L gene to outside databases

Previous GC identifers: GC14M044442 GC14M040916 GC14M045110 GC14M046189 GC14M027238


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for RPL10L Gene:
This gene encodes a protein sharing sequence similarity with ribosomal protein L10. It is not currently known
whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is
independent of the ribosome. This gene is intronless. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL10L Gene:
RPL10L (ribosomal protein L10-like) is a protein-coding gene. Diseases associated with RPL10L include ovarian cancer. GO annotations related to this gene include structural constituent of ribosome. An important paralog of this gene is RPL10.

UniProtKB/Swiss-Prot: RL10L_HUMAN, Q96L21
Function: May play a role in compensating for the inactivated X-linked gene during spermatogenesis

Gene Wiki entry for RPL10L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000014.9  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL10L gene promoter:
         GR   STAT1   GR-beta   STAT1beta   RelA   NF-kappaB   LCR-F1   STAT1alpha   GR-alpha   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RPL10L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL10L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q21.2   Ensembl cytogenetic band:  14q21.2   HGNC cytogenetic band: 14q21.2

RPL10L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL10L gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M047120:  view genomic region     (about GC identifiers)

Start:
47,120,216 bp from pter      End:
47,121,028 bp from pter
Size:
813 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RL10L_HUMAN, Q96L21 (See protein sequence)
Recommended Name: 60S ribosomal protein L10-like  
Size: 214 amino acids; 24519 Da
Miscellaneous: This gene has no introns in its coding regions, and therefore was most likely produced by
retrotransposition of the original X-linked gene during evolution
1 PDB 3D structure from and Proteopedia for RPL10L:
3J3B (3D)    
Secondary accessions: Q8IUD1

Explore the universe of human proteins at neXtProt for RPL10L: NX_Q96L21

Explore proteomics data for RPL10L at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys30, Lys74, Lys101, Lys121, Lys208
  • Modification sites at PhosphoSitePlus

  • See RPL10L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_542784.1  
    ENSEMBL proteins: 
     ENSP00000298283  

    RPL10L Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for RPL10L
    GenScript Custom Purified and Recombinant Proteins Services for RPL10L
    Novus Biologicals RPL10L Proteins
    Novus Biologicals RPL10L Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPL10L

    RPL10L Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for RPL10L
    OriGene Custom Antibody Services for RPL10L
    Novus Biologicals RPL10L Antibodies
    Abcam antibodies for RPL10L
    Cloud-Clone Corp. Antibodies for RPL10L
    Search ThermoFisher Antibodies for RPL10L
    LSBio Antibodies in human, mouse, rat for RPL10L

    RPL10L Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RPL10L
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RPL10L
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RPL10L
    Cloud-Clone Corp. CLIAs for RPL10L


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RPL: L ribosomal proteins

    3 InterPro protein domains:
     IPR001197 Ribosomal_L10e
     IPR016180 Ribosomal_L10e/L16
     IPR018255 Ribosomal_L10e_CS

    Graphical View of Domain Structure for InterPro Entry Q96L21

    ProtoNet protein and cluster: Q96L21

    1 Blocks protein domain: IPB001197 Ribosomal protein L10E

    UniProtKB/Swiss-Prot: RL10L_HUMAN, Q96L21
    Similarity: Belongs to the ribosomal protein L10e family


    RPL10L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RL10L_HUMAN, Q96L21
    Function: May play a role in compensating for the inactivated X-linked gene during spermatogenesis

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
         
    RPL10L for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL10L
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL10L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPL10L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPL10L

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPL10L:
    hsa-mir-16-5p (MIRT031544)

    Block miRNA regulation of human, mouse, rat RPL10L using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate RPL10L
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RPL10L
    Predesigned siRNA for gene silencing in human, mouse, rat RPL10L

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RPL10L

    Clone
    Products:
         
    OriGene clones in human, mouse for RPL10L (see all 8)
    OriGene ORF clones in mouse, rat for RPL10L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL10L (NM_080746)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL10L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL10L

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RPL10L
    Browse ESI BIO Cell Lines and PureStem Progenitors for RPL10L 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL10L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus4
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005840ribosome ----
    GO:0022625cytosolic large ribosomal subunit NAS12490704

    RPL10L for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for RPL10L About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for RPL10L):
        Ribosome


    RPL10L for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL10L
    Interactions:

        Search GeneGlobe Interaction Network for RPL10L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL10L (Q96L212, 3 ENSP000002982834) via UniProtKB, MINT, STRING, and/or I2D (see all 225)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K14Q995582, 3MINT-48839 I2D: score=2 
    GABARAPL1Q9H0R83I2D: score=2 
    ATG14Q6ZNE53I2D: score=1 
    CAMKK2Q96RR43I2D: score=1 
    DDA1Q9BW613I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--
    GO:0007283spermatogenesis IEP12490704

    RPL10L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL10L (RL10L)

    3 DrugBank Compounds for RPL10L    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ANISOMYCIN-- --target--10592235
    Alpha-Hydroxy-Beta-Phenyl-Propionic Acid-- --target--10592235
    PUROMYCIN-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RPL10L gene: 
    NM_080746.2  

    Unigene Cluster for RPL10L:

    Ribosomal protein L10-like
    Hs.308332  [show with all ESTs]
    Unigene Representative Sequence: BU561557
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000298283(uc001wwg.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RPL10L using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate RPL10L
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RPL10L
    Predesigned siRNA for gene silencing in human, mouse, rat RPL10L
    Clone
    Products:
         
    OriGene clones in human, mouse for RPL10L (see all 8)
    OriGene ORF clones in mouse, rat for RPL10L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RPL10L (NM_080746)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPL10L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL10L
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL10L
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat RPL10L
      QuantiTect SYBR Green Assays in human, mouse, rat RPL10L
      QuantiFast Probe-based Assays in human, mouse, rat RPL10L

    Additional mRNA sequence: 

    AB063608.1 AK130863.1 BC014310.1 BC066312.1 

    1 DOTS entry:

    DT.100035915 

    Selected AceView cDNA sequences (see all 28):

    NM_080746 AK130863 BX095190 AB063608 BI825154 BI559904 BI561024 BQ441356 
    BC066312 BP368907 BU570130 BP370342 BC014310 BG721101 AI027614 BU569470 
    BF979770 BQ428774 BI828161 BF980074 AI223104 BU561253 AI001784 BU561178 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RPL10L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGTCTGAC
    RPL10L Expression
    About this image

    RPL10L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL10L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.308332

    UniProtKB/Swiss-Prot: RL10L_HUMAN, Q96L21
    Tissue specificity: Testis specific

        Custom PCR Arrays for RPL10L
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RPL10L
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat RPL10L
    QuantiTect SYBR Green Assays in human, mouse, rat RPL10L
    QuantiFast Probe-based Assays in human, mouse, rat RPL10L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL10L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL10L gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl10l1 , 5 ribosomal protein L10-like1, 5 83.96(n)1
    94.86(a)1
      12 (27.44 cM)5
    2382171  NM_001162933.11  NP_001156405.11 
     662833795 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    93(a)
    1 → many
    AADN03016467.1(7-787)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    93(a)
    1 → many
    2(86474899-86478644)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.62152 Transcribed sequence with strong similarity to protein spP27635 (H.sapiens) RL10_HUMAN 60S ribosomal protein L10 (QM protein) (Tumor suppressor QM) (Laminin receptor homolog) less 82.15(n)    142018860 
    zebrafish
    (Danio rerio)
    Actinopterygii rpl106
    ribosomal protein L10
    87(a)
    1 → many
    23(20001107-20004409) ENSDARG00000025581
    fruit fly
    (Drosophila melanogaster)
    Insecta RpL106
    Ribosomal protein L10
    74(a)
    1 → many
    3L(23086290-23088571)
    worm
    (Caenorhabditis elegans)
    Secernentea rpl-101 rpl-10 67.46(n)
    73.21(a)
      174311  NM_063306.5  NP_495707.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL106
    Protein component of the large (60S) ribosomal sub...
    62(a)
    1 → many
    XII(282927-283592) YLR075W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SAG241 SAG24 64.56(n)
    68.93(a)
      842976  NM_105329.1  NP_564878.1 
    rice
    (Oryza sativa)
    Liliopsida Os11g02208001 Os11g0220800 65.38(n)
    68.75(a)
      4350098  NM_001074056.1  NP_001067524.1 


    ENSEMBL Gene Tree for RPL10L (if available)
    TreeFam Gene Tree for RPL10L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RPL10L gene
    RPL102  
    1 SIMAP similar gene for RPL10L using alignment to 1 protein entry:     RL10L_HUMAN:
    RPL10

    RPL10L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for RPL10L (see all 109)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1479853411,2
    --47119810(+) AACAAC/TGTACA 1 -- ds50010--------
    rs1407416241,2
    --47119814(+) ATGTAC/TAGAAA 1 -- ds50010--------
    rs98060881,2
    C,F,H--47119832(+) AAAAAC/TATAAG 1 -- ds500116Minor allele frequency- T:0.08NS EA NA WA 2176
    rs1136037031,2
    C,F--47120049(+) CTAAAT/ATTAAA 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs125894511,2
    C,F,H--47120056(+) TAAAGT/CGTTTG 1 -- ds50018Minor allele frequency- C:0.11NS EA NA WA 774
    rs1407456151,2
    C--47120104(+) GAAGC-/AAAGGA 1 -- ds50010--------
    rs1389791631,2
    --47120133(+) AAACTC/GAATAA 1 -- ds50010--------
    rs755672221,2
    C,F--47120249(+) TAAGCA/GTAAGT 1 -- ut311Minor allele frequency- G:0.02EA 120
    rs1443476601,2
    F--47120316(+) CGCCAC/TTTGTC 2 K syn11Minor allele frequency- T:0.00NA 4470
    rs2013209091,2
    --47120335(+) CATGAA/CTGGGA 2 S I mis10--------

    HapMap Linkage Disequilibrium report for RPL10L (47120216 - 47121028 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RPL10L:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1920n71CNV Loss21882294
    nsv901863CNV Loss21882294
    nsv517764CNV Loss19592680
    esv2751278CNV Gain17911159

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL10L
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL10L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for RPL10L:    
    About MalaCards
    ovarian cancer


    RPL10L for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPL10L

    Export disorders for RPL10L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RPL10L gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with RPL10L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functional second genes generated by retrotransposition of the X- linked ribosomal protein genes. (PubMed id 12490704)1, 2, 9 Uechi T.... Kenmochi N. (Nucleic Acids Res. 2002)
    2. Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes. (PubMed id 19123937)1, 3 Balasubramanian S....Gerstein M. (Genome Biol. 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PubMed id 21319273)1 Neganova I....Lako M. (Stem Cells 2011)
    9. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (amp 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 140801 HGNC: 17976 AceView: RPL10L Ensembl:ENSG00000165496 euGenes: HUgn140801
    ECgene: RPL10L Kegg: 140801 H-InvDB: RPL10L

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RPL10L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RPL10L gene:
    Search GeneIP for patents involving RPL10L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for RPL10L   OriGene RNAi products in human, mouse, rat for RPL10L  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RPL10L  
     OriGene qSTAR qPCR primer pairs in human, mouse for RPL10L   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RPL10L   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RPL10L   OriGene Custom Protein Services for RPL10L  

     
     
     Block miRNA regulation of human, mouse, rat RPL10L using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RPL10L
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL10L Predesigned siRNA for gene silencing in human, mouse, rat RPL10L
     QuantiFast Probe-based Assays in human, mouse, rat RPL10L QuantiTect SYBR Green Assays in human, mouse, rat RPL10L
     Custom PCR Arrays for RPL10L Search Chromatin IP Primers for RPL10L
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat RPL10L Search GeneGlobe Interaction Network for RPL10L
     Regulatory tfbs in RPL10L promoter
     GenScript Custom Purified and Recombinant Proteins Services for RPL10L GenScript cDNA clones with any tag delivered in your preferred vector for RPL10L
     GenScript Custom Assay Services for RPL10L GenScript Custom overexpressing Cell Line Services for RPL10L
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RPL10L (RL10L)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RPL10L antibodies
     RPL10L proteins
     RPL10L lysates
     Antibodies for RPL10L
     See all of Abcam's Antibodies, Kits and Proteins for RPL10L
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RPL10L
     Antibodies for RPL10L
     ELISAs for RPL10L
     CLIAs for RPL10L



     Browse ESI BIO Cell Lines and PureStem Progenitors for RPL10L
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL10L
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RPL10L
     Browse SwitchGear Promoter luciferase reporter plasmids for RPL10L
     Search ThermoFisher Antibodies for RPL10L
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPL10L
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPL10L
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPL10L
     LSBio Antibodies in human, mouse, rat for RPL10L
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RPL10L gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4