Aliases for RPL10A Gene
External Ids for RPL10A Gene
Previous HGNC Symbols for RPL10A Gene
Previous GeneCards Identifiers for RPL10A Gene
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPL10A Gene
RPL10A (Ribosomal Protein L10a) is a Protein Coding gene. Diseases associated with RPL10A include myopathy, lactic acidosis, and sideroblastic anemia and bowen-conradi syndrome. Among its related pathways are Gene Expression and Metabolism. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.