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RPL10A Gene

protein-coding   GIFtS: 63
GCID: GC06P037295

Ribosomal Protein L10a


(Previous symbol: NEDD6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribosomal Protein L10a1 2     60S Ribosomal Protein L10a2
NEDD61 2 3     Csa-192
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 62 3     L10A2
NEDD-62 3     CSA-193
CSA192 5     

External Ids:    HGNC: 102991   Entrez Gene: 47362   Ensembl: ENSG000001987557   OMIM: 6156605   UniProtKB: P629063   

Export aliases for RPL10A gene to outside databases

Previous GC identifers: GC06P035438 GC06P035483 GC06P035544 GC06P035156 GC06P035582 GC06P035784 GC06P036309


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPL10A Gene:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This
gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of
ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by
cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal
protein L10a gene is downregulated in neural precursor cells during development. This gene previously was
referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed
RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome. (provided by RefSeq, Jul 2008)

GeneCards Summary for RPL10A Gene:
RPL10A (ribosomal protein L10a) is a protein-coding gene. Diseases associated with RPL10A include diamond-blackfan anemia, and treacher collins syndrome. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for RPL10A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPL10A gene promoter:
         GR   ER-alpha   Tal-1   HSF1 (long)   E47   ARP-1   HSF1short   GR-alpha   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPL10A promoter sequence
   Search Chromatin IP Primers for RPL10A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPL10A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

RPL10A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPL10A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P037295:  view genomic region     (about GC identifiers)

Start:
35,436,178 bp from pter      End:
35,438,562 bp from pter
Size:
2,385 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RL10A_HUMAN, P62906 (See protein sequence)
Recommended Name: 60S ribosomal protein L10a  
Size: 217 amino acids; 24831 Da
1 PDB 3D structure from and Proteopedia for RPL10A:
3J3B (3D)    
Secondary accessions: B2R801 P52859 P53025 Q5TZT6 Q8J013

Explore the universe of human proteins at neXtProt for RPL10A: NX_P62906

Explore proteomics data for RPL10A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys106, Lys118, Lys130, Lys133
  • Modification sites at PhosphoSitePlus

  • See RPL10A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_009035.3  
    ENSEMBL proteins: 
     ENSP00000363018  
    Reactome Protein details: P62906

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RPL: L ribosomal proteins

    Selected InterPro protein domains (see all 6):
     IPR023673 Ribosomal_L1_CS
     IPR002143 Ribosomal_L1
     IPR023674 Ribosomal_L1-like
     IPR016095 Ribosomal_L1_3-a/b-sand
     IPR028364 Ribosomal_L1/biogenesis

    Graphical View of Domain Structure for InterPro Entry P62906

    ProtoNet protein and cluster: P62906

    1 Blocks protein domain: IPB002143 Ribosomal protein L1

    UniProtKB/Swiss-Prot: RL10A_HUMAN, P62906
    Similarity: Belongs to the ribosomal protein L1P family


    RPL10A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RPL10A:
    60S ribosomal protein L10A

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0003735structural constituent of ribosome NAS12962325
    GO:0044822poly(A) RNA binding IDA--
         
    RPL10A for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for RPL10A:
     Increased G2M DNA content  Increased cell death HMECs cel  S arrest  Synthetic lethal with c-Myc af 

    Animal Models:
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    miRNA
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    hsa-mir-100-5p (MIRT048513), hsa-mir-1260b (MIRT052719), hsa-mir-324-3p (MIRT042813), hsa-mir-339-3p (MIRT038179)

    Block miRNA regulation of human, mouse, rat RPL10A using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0015934large ribosomal subunit ----
    GO:0022625cytosolic large ribosomal subunit IDA12962325

    RPL10A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RPL10A About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CFTR translational fidelity class I mutations
    CFTR translational fidelity class I mutations 0.60
    Ribosome0.54
    Cytoplasmic Ribosomal Proteins0.60
    2Influenza Viral RNA Transcription and Replication
    Viral mRNA Translation0.94
    Eukaryotic Translation Initiation0.89
    Peptide chain elongation0.94
    Cap-dependent Translation Initiation0.89
    Nonsense Mediated Decay Independent of the Exon Junction Complex0.94
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    Formation of a pool of free 40S subunits0.94
    Nonsense-Mediated Decay0.89
    3Gene Expression
    Gene Expression0.40
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RPL10A
        CFTR translational fidelity (class I mutations)

    1 BioSystems Pathway for RPL10A
        Cytoplasmic Ribosomal Proteins

    Selected Reactome Pathways for RPL10A (see all 9)
        Peptide chain elongation
    Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
    Viral mRNA Translation
    GTP hydrolysis and joining of the 60S ribosomal subunit
    SRP-dependent cotranslational protein targeting to membrane


    1 Kegg Pathway  (Kegg details for RPL10A):
        Ribosome


    RPL10A for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPL10A
    Interactions:

        Search GeneGlobe Interaction Network for RPL10A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPL10A (P629062, 3 ENSP000003630184) via UniProtKB, MINT, STRING, and/or I2D (see all 442)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL26P612542, 3, ENSP000002938424MINT-6542674 MINT-6489539 I2D: score=6 STRING: ENSP00000293842
    RPL8P629172, 3, ENSP000002625844MINT-6542674 MINT-6489539 I2D: score=6 STRING: ENSP00000262584
    RPL11P629132, 3, ENSP000003636764MINT-6542674 MINT-6489539 I2D: score=3 STRING: ENSP00000363676
    RPS3P233962, 3, ENSP000002785724MINT-6542674 MINT-6489539 I2D: score=3 STRING: ENSP00000278572
    RPL12P300502, 3, ENSP000003547394MINT-6542674 MINT-6489539 I2D: score=2 STRING: ENSP00000354739
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--

    RPL10A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPL10A (RL10A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RPL10A gene: 
    NM_007104.4  

    Unigene Clusters for RPL10A:

    Ribosomal protein L10a
    Hs.148340  [show with all ESTs], Hs.546269  [show with all ESTs]
    Unigene Representative Sequences: BM554127, BF972106
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322203(uc003okp.1) ENST00000467020(uc003oks.1) ENST00000490335
    ENST00000464112 ENST00000478340
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat RPL10A
      QuantiFast Probe-based Assays in human, mouse, rat RPL10A

    Additional mRNA sequence: 

    AB082926.1 AK313181.1 BC006791.1 BC011366.1 BC070216.1 BC116456.1 BT020040.1 BT020041.1 
    U12404.1 

    Selected DOTS entries (see all 80):

    DT.91880849  DT.100738954  DT.99926595  DT.91870722  DT.87006915  DT.100871230  DT.97861561  DT.91870447 
    DT.100738959  DT.91691015  DT.120926197  DT.91870300  DT.99926600  DT.100738936  DT.100738941  DT.91870496 
    DT.92405105  DT.100738923  DT.100738935  DT.121350363  DT.91974200  DT.100871462  DT.91973901  DT.95275225 

    Selected AceView cDNA sequences (see all 3987):

    BU930961 BQ055522 BM970682 CB149517 CA420991 BQ683967 BQ054848 BE856153 
    BM552703 BQ934413 BM772315 BQ064646 BQ052572 AW405432 BG336998 AI460328 
    BF128742 BF974818 BG397491 BU931851 BE731653 CA307327 BU188990 BQ430107 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RPL10A (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b · 6c
    SP1:        -     -                 -     -     -     -     -                                             
    SP2:        -     -                                         -                                             
    SP3:                                -     -     -     -     -                                             
    SP4:        -     -                                                                                       
    SP5:        -     -                 -     -     -     -     -                                             


    ECgene alternative splicing isoforms for RPL10A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPL10A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCAAGCCCC
    RPL10A Expression
    About this image


    RPL10A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Endoderm (Gastrulation Derivatives)
             Endoderm-like cells
     
     Tonsil (Hematopoietic System)
    RPL10A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPL10A Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.148340 Hs.546269
        Custom PCR Arrays for RPL10A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPL10A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPL10A gene from Selected species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpl10a1 , 5 ribosomal protein L10A1, 5 89.09(n)1
    100(a)1
      17 (14.65 cM)5
    198961  NM_011287.21  NP_035417.21 
     283284715 
    chicken
    (Gallus gallus)
    Aves RPL10A1 ribosomal protein L10a 82.8(n)
    94.47(a)
      419895  XM_418020.4  XP_418020.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPL10A6
    ribosomal protein L10a
    95(a)
    1 ↔ 1
    4(124394828-124402962)
    African clawed frog
    (Xenopus laevis)
    Amphibia rpl10a-prov2 ribosomal protein L10a 79.64(n)    BC041308.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb94f082 wufb94f08 81.97(n)   323305  BC059454.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG72833
    RpL10Ab1
    protein biosynthesis structural
    constituent of more3
    Ribosomal protein L10Ab1
    77(a)
    (best of 2)3
    71.74(n)1
    76.96(a)1
      68E13
    393381  NM_140257.21  NP_648514.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y71F9AL.13b3
    rpl-11
    rpl-11 75(a)
    (best of 2)3
    66.98(n)1
    73.02(a)1
      I(2875432-2875947)3
    1718531  NM_058660.51  NP_491061.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPL1A(YPL220W)4
    RPL1A1
    N-terminally acetylated protein component of the large more4
    RPL1A1
    59.84(n)1
    60(a)1
      16(135790-136443)4
    8558811, 4  NP_015104.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons PGY11 PGY1 62.17(n)
    64.19(a)
      817299  NM_128313.6  NP_565654.1 
    rice
    (Oryza sativa)
    Liliopsida AK122095.12   -- 76.77(n)    AK122095.1 


    ENSEMBL Gene Tree for RPL10A (if available)
    TreeFam Gene Tree for RPL10A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPL10A gene

    RPL10A for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RPL10A (see all 15)
    PGOHUM00000247900 PGOHUM00000250668 PGOHUM00000234919 PGOHUM00000235091 PGOHUM00000234546


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPL10A (see all 140)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1452178661,2
    --35435505(+) TGGACA/GGAGGA 1 -- us2k10--------
    rs1511749391,2
    C--35435542(+) GTGCAG/ATGCTG 1 -- us2k11Minor allele frequency- A:0.01NS 148
    rs1155200481,2
    F--35435574(+) TATTCC/ATGTAG 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs38234331,2
    C,F,H--35435593(-) TAAGGC/TGTCTA 1 -- us2k19Minor allele frequency- T:0.02NS EA NA 1234
    rs455585311,2
    C,F--35435602(+) TATTCA/GTAGCA 1 -- us2k18Minor allele frequency- G:0.06NS WA NA 566
    rs38234321,2
    C,F,H--35435736(-) CTCGTG/AGTAAG 1 -- us2k126Minor allele frequency- A:0.18MN EA NS NA WA CSA 3031
    rs413455471,2
    F--35435736(-) ACTCGG/AGTAAG 1 -- us2k11Minor allele frequency- A:0.07EA 180
    rs455329321,2
    C,F--35435761(+) AGGTGC/TTGAGG 1 -- us2k15Minor allele frequency- T:0.01NS 188
    rs1874303561,2
    --35435852(+) CGTGCC/TGGAAT 1 -- us2k10--------
    rs1469057281,2
    --35435965(+) GCGAAA/TCGGCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RPL10A (35436178 - 35438562 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RPL10A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv528351CNV Loss19592680
    nsv830641CNV Loss17160897
    nsv885799CNV Loss21882294
    nsv519370CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPL10A
    DNA2.0 Custom Variant and Variant Library Synthesis for RPL10A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615660    OMIM disorders: --

    5 diseases for RPL10A:    
    About MalaCards
    diamond-blackfan anemia    treacher collins syndrome    influenza    breast cancer
    malaria


    RPL10A for disorders           About GeneDecksing

    Genetic Association Database (GAD): RPL10A
    Human Genome Epidemiology (HuGE) Navigator: RPL10A (1 document)

    Export disorders for RPL10A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPL10A gene, integrated from 10 sources (see all 57):
    (articles sorted by number of sources associating them with RPL10A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of genes downregulated in the thymus by cyclosporin-A: preliminary characterization of clone CSA-19. (PubMed id 7609734)1, 2, 3 Fisicaro N....Pearse M. (Mol. Immunol. 1995)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    5. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. (PubMed id 12962325)1, 2 Odintsova T.I....Karpova G.G. (J. Protein Chem. 2003)
    6. Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex. (PubMed id 9647638)1, 3 Tripodis N....Ragoussis J. (Genome Res. 1998)
    7. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    8. Structures of the human and Drosophila 80S ribosome. (PubMed id 23636399)2 Anger A.M.... Beckmann R. (Nature 2013)
    9. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4736 HGNC: 10299 AceView: RPL10A Ensembl:ENSG00000198755 euGenes: HUgn4736
    ECgene: RPL10A Kegg: 4736 H-InvDB: RPL10A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPL10A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPL10A gene:
    Search GeneIP for patents involving RPL10A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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