Aliases for RPIA Gene
External Ids for RPIA Gene
Previous GeneCards Identifiers for RPIA Gene
The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010]
GeneCards Summary for RPIA Gene
RPIA (Ribose 5-Phosphate Isomerase A) is a Protein Coding gene. Diseases associated with RPIA include Ribose 5-Phosphate Isomerase Deficiency and Ribose-5-P Isomerase Deficiency. Among its related pathways are Glycosaminoglycan metabolism and Pentose phosphate pathway. GO annotations related to this gene include carbohydrate binding and ribose-5-phosphate isomerase activity.