RPH3A Gene
protein-coding GIFtS: 56
GCID: GC12P113012
|
|
rabphilin 3A homolog (mouse)
| |
Aliases
for RPH3A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rabphilin 3A Homolog (Mouse)1 2 | | KIAA09851 3 5 | | Exophilin-13 | | Rabphilin1 | | Rabphilin-3A1 | | Exophilin-13 |
Export aliases for RPH3A gene to outside databasesPrevious GC identifers: GC12P112124 GC12P112748 GC12P111641 GC12P111627 GC12P111692 GC12P113229 GC12P110241 |
Summaries
for RPH3A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RPH3A:
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication.RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3Aeffector (Lin et al., 2007 (PubMed 17149709)).(supplied by OMIM, Jul 2008)
UniProtKB/Swiss-Prot: RP3A_HUMAN, Q9Y2J0Function: Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/orsynaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerveterminal (By similarity)
Gene Wiki entry for RPH3A
|
Genomic Views
for RPH3A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RPH3A gene promoter:
STAT5B AML1a ATF-2 Lmo2 HNF-1A Roaz Evi-1 PPAR-alpha CRE-BP1 HNF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RPH3A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPH3A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.13 Ensembl cytogenetic band: 12q24.13 HGNC cytogenetic band: 12q24.13RPH3A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P113012: view genomic region
(about GC identifiers)
Start:
|
113,008,184 bp from pter |
End:
|
113,336,686 bp from pter |
Size:
|
328,503 bases |
Orientation:
|
plus strand |
|
Proteins
for RPH3A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RP3A_HUMAN, Q9Y2J0 (See
protein sequence)Recommended Name: Rabphilin-3A Size: 694 amino acids; 76872 Da
Subunit: Monomer. Interacts with RAB3A, RAB3B, RAB3C, RAB3D, RAB8A, RAB27A and RAB27B (By similarity)
Subcellular location: Cell junction, synapse (By similarity). Membrane; Peripheral membrane protein (By similarity)
Sequence caution: Sequence=BAA76829.2; Type=Erroneous initiation;
Secondary accessions: B7Z3C3 Q96AE0Alternative splicing: 2 isoforms: Q9Y2J0-1 Q9Y2J0-2 Explore the universe of human proteins at neXtProt for RPH3A: NX_Q9Y2J0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2J0
RPH3A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001137326.1 NP_055769.2
ENSEMBL proteins: ENSP00000446789 ENSP00000446570 ENSP00000449705 ENSP00000440384 ENSP00000446780 ENSP00000447639 ENSP00000447306 ENSP00000446556 ENSP00000450382 ENSP00000449613 ENSP00000447505 ENSP00000449650 ENSP00000374036 ENSP00000448100 ENSP00000447083 ENSP00000448297 ENSP00000405357 ENSP00000450216 ENSP00000450347 ENSP00000448662 ENSP00000448616 ENSP00000447971 ENSP00000413254 ENSP00000408889
Human Recombinant Protein Products:
Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11): About this table
RPH3A for ontologies About GeneDecksing
RPH3A Antibody Products:
Assay Products for RPH3A: |
Protein
Domains /
Families
for RPH3A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RPH3A for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry Q9Y2J0ProtoNet protein and cluster: Q9Y2J0 4 Blocks protein families: IPB000008 C2 domain IPB000306 Zn-finger IPB001565 Synaptotagmin signature IPB003315 Rabphilin-3A effector
UniProtKB/Swiss-Prot: RP3A_HUMAN, Q9Y2J0Domain: Binds calcium via the C2 domains. The calcium-bound C2 domains mediate interactions with phospholipid bilayers(By similarity)Similarity: Contains 2 C2 domainsSimilarity: Contains 1 FYVE-type zinc fingerSimilarity: Contains 1 RabBD (Rab-binding) domain |
Function
for RPH3A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RP3A_HUMAN, Q9Y2J0Function: Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/orsynaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerveterminal (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPH3A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPH3A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): RPH3A (NM_006987) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPH3A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPH3A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPH3A |
Gene Ontology (GO): 5/12 molecular function terms (GO ID links to tree view) (see all 12): About this table
RPH3A for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RPH3A:
Animal Models:
Mouse knock-out Rph3atm1Sud for RPH3A
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Rph3a):
RPH3A for phenotypes About GeneDecksing
|
Pathways & Interactions
for RPH3A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | |
1  BioSystems Pathway for RPH3A
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPH3A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/19 Interacting proteins for RPH3A (Q9Y2J01, 2, 3 ENSP000004132544) via UniProtKB, MINT, STRING, and/or I2D (see all 19)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006886 | intracellular protein transport |
IEA | -- | | GO:0007420 | brain development |
-- | -- |
RPH3A for ontologies About GeneDecksing
|
Drugs & Compounds
for RPH3A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RPH3A for compounds About GeneDecksing
 Browse Tocris compounds for RPH3A
10 Novoseek chemical compound relationships for RPH3A gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gtp |
65.5 |
15 |
7926025 (4), 10025402 (1), 7802677 (1), 8886977 (1) (see all 9) |
| phospholipid |
47.1 |
16 |
8262955 (5), 8226731 (2), 7826360 (1), 8605005 (1) (see all 9) |
| gdp |
44.5 |
3 |
7926025 (2), 7945346 (1) |
| phosphatidylserine |
30.2 |
2 |
7999065 (2) |
| calcium |
19 |
11 |
8226731 (2), 7999065 (2), 7826360 (1), 9425005 (1) (see all 7) |
| forskolin |
10.3 |
1 |
9425005 (1) |
| magnesium |
0 |
2 |
10025402 (1), 9163333 (1) |
| lipid |
0 |
4 |
8554624 (3) |
| zinc |
0 |
2 |
8756657 (1), 10504306 (1) |
| tyrosine |
0 |
1 |
17223267 (1) |
Search CenterWatch for drugs/clinical trials and news about RPH3A / RP3A
|
Transcripts
for RPH3A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RPH3A gene (2 alternative transcripts): NM_001143854.1 NM_014954.3 Unigene Cluster for RPH3A: Rabphilin 3A homolog (mouse) Hs.21239 [show with all ESTs]Unigene Representative Sequence: BX64728118/29 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 29): ENST00000549736 ENST00000548197 ENST00000547686 ENST00000543106(uc009zwe.1)
ENST00000551593 ENST00000546426 ENST00000551748 ENST00000546703 ENST00000547840
ENST00000547728 ENST00000549769 ENST00000552667 ENST00000389385(uc001ttz.3 uc001tty.3)
ENST00000550901 ENST00000551198 ENST00000551052 ENST00000415485(uc010syl.2 uc010sym.2)
ENST00000552679
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPH3A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPH3A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): RPH3A (NM_006987) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RPH3A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPH3A |
Additional cDNA sequence: AB023202.1 AK295696.1 AK296296.1 AK316112.1 BC002605.2 BC009843.2 BC017259.2 BX647281.1 14 DOTS entries: DT.114969 DT.101978125 DT.121209975 DT.121209973 DT.95163994 DT.121210006 DT.121209977 DT.121209979 DT.121209981 DT.121209989 DT.121209994 DT.121209998 DT.91837231 DT.95316924 24/89 AceView cDNA sequences (see all 89): CR613722 BC002605 AA976078 BX647281 BM716888 AA338374 AA338373 BC009843 BX375754 AB023202 AW207073 AA325807 BE857186 N54215 BU738474 AI421373 BC017259 H41541 BI756895 BI666881 R90757 AA325143 AA319224 BG770493
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RPH3A (see all 8) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | · |
|---|
|
| SP1: | | | | | - | | | | | | | | | | - | | | | - | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | - | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18c | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23 | ^ | 24 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RPH3A
|
Expression
for RPH3A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RPH3A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACAACCACC
About this image
See RPH3A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RPH3A
SOURCE GeneReport for Unigene cluster: Hs.21239
SABiosciences Expression via Pathway-Focused PCR Array including RPH3A:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPH3A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RPH3A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPH3A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPH3A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPH3A |
Orthologs
for RPH3A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RPH3A gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RPH3A1 |
rabphilin 3A homolog (mouse) |
73.15(n)
76.62(a) |
|
416886 XM_415177.3 XP_415177.3 |
lizard
(Anolis carolinensis) |
Reptilia |
RPH3A6 |
-- |
71(a) |
1 ↔ 1 |
GL343282.1(384945-406153) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BJ638931.12 |
-- |
80.86(n) |
|
BJ638931.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
rph3ab1 |
rabphilin 3A homolog (mouse), b |
66.96(n)
70.42(a) |
|
563377 XM_686740.4 XP_691832.4 |
fruit fly
(Drosophila melanogaster) |
Insecta |
rabphilin-3A3
Rph1 |
synaptic vesicle endocytosis protein
transporter3
Rabphilin1 |
39(a)3
50.42(n)1
40.44(a)1 |
|
320021 NM_132423.21 NP_572651.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
rbf-11 |
Protein RBF-1 |
50.91(n)
44.41(a) |
|
175943 NM_001027396.2 NP_001022567.1 |
ENSEMBL Gene Tree for RPH3A (if available)
TreeFam Gene Tree for RPH3A (if available) |
Paralogs
for RPH3A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RPH3A gene
- SYTL42 DOC2B2 SYTL52 SYTL12 DOC2A2 SYTL32 SYTL22
18/23 SIMAP similar genes for RPH3A using alignment to 21 protein entries: RP3A_HUMAN (see all proteins)
(see all similar genes):DOC2A RPH3AL DOC2B PRKCA PRKCG SYT1
CHR11SYT PRKCB SYT6 SYT7 RIMS2 SYT10
SYTL4 SYT2 SYT4 LOC392742 SYTL2 SYT11
RPH3A for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RPH3A
PGOHUM00000261113
|
Genomic Variants
for RPH3A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RPH3A (113008184 - 113258184 bp, first 250kb of RPH3A)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RPH3A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPH3A |
|
Disorders
/ Diseases
for RPH3A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RPH3A for disorders About GeneDecksing
OMIM gene information: 612159
OMIM disorders: --
4  diseases for RPH3A: About MalaCardshuntington's disease pheochromocytoma adenocarcinoma neuronitis
1 Novoseek disease relationship for RPH3A gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
5.4 |
1 |
18854424 (1) |
Human Genome Epidemiology (HuGE) Navigator: RPH3A (1 document)
Export disorders for RPH3A gene to outside databases
|
Publications
for RPH3A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RPH3A gene, integrated from 9 sources (see all 84):
(articles sorted by number of sources associating them with RPH3A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells. (PubMed id 7822236)1, 3 Inagaki N....Seino S. (1994)
- Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. (PubMed id 12578829)1, 9 Fukuda M. (2003)
- Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease. (PubMed id 15207266)1, 9 Dalfo E....Ferrer I. (2004)
- Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. (PubMed id 10025402)1, 9 Ostermeier C. and Brunger A.T. (1999)
- Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. (PubMed id 17877635)1, 9 Smith R....Li J.Y. (2007)
- Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3a. (PubMed id 12937130)1, 9 Rastaldi M.P....D'Amico G. (2003)
- Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin. (PubMed id 8901523)1, 9 Perin M.S. (1996)
- Identification as beta-adducin of a protein interacting with rabphilin-3A in the presence of Ca2+ and phosphatidylserine. (PubMed id 7999065)1, 9 Miyazaki M....Takai Y. (1994)
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External Searches for RPH3A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing RPH3A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing RPH3A gene
(According to HUGE)
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Specialized Databases showing RPH3A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for RPH3A | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for RPH3A gene:
Search GeneIP for patents involving RPH3A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RPH3A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RPH3A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RPH3A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for RPH3A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RPH3A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RPH3A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RPH3A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RPH3A | | OriGene Custom Protein Services for RPH3A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RPH3A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RPH3A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPH3A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPH3A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPH3A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPH3A |
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| | | | Search Tocris compounds for RPH3A |
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 | | | RPH3A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPH3A |
|  |  |  | | | | Search ThermoFisher Antibodies for RPH3A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPH3A |
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