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RPAP3 Gene

protein-coding   GIFtS: 50
GCID: GC12M048057

RNA Polymerase II Associated Protein 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RNA Polymerase II Associated Protein 31 2
RNA Polymerase II-Associated Protein 32

External Ids:    HGNC: 261511   Entrez Gene: 796572   Ensembl: ENSG000000051757   OMIM: 6114775   UniProtKB: Q9H6T33   

Export aliases for RPAP3 gene to outside databases

Previous GC identifers: GC12M046344 GC12M045086


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RPAP3 Gene:
This gene encodes an RNA polymerase II-associated protein. The encoded protein may function in transcriptional
regulation and may also regulate apoptosis. Alternatively spliced transcript variants have been described.
(provided by RefSeq, Mar 2009)

GeneCards Summary for RPAP3 Gene:
RPAP3 (RNA polymerase II associated protein 3) is a protein-coding gene. An important paralog of this gene is SGTB.

UniProtKB/Swiss-Prot: RPAP3_HUMAN, Q9H6T3
Function: Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting
that it is required to connect RNA polymerase II to regulators of protein complex formation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPAP3 gene promoter:
         Nkx3-1   Nkx3-1 v4   AML1a   AP-1   Nkx3-1 v1   PPAR-alpha   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPAP3 promoter sequence
   Search Chromatin IP Primers for RPAP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPAP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.11   Ensembl cytogenetic band:  12q13.11   HGNC cytogenetic band: 12q13.11

RPAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPAP3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M048057:  view genomic region     (about GC identifiers)

Start:
48,055,715 bp from pter      End:
48,099,844 bp from pter
Size:
44,130 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RPAP3_HUMAN, Q9H6T3 (See protein sequence)
Recommended Name: RNA polymerase II-associated protein 3  
Size: 665 amino acids; 75719 Da
Subunit: Tightly associated with the RNA polymerase II complex
Secondary accessions: B4DRW9 Q6PHR5
Alternative splicing: 3 isoforms:  Q9H6T3-1   Q9H6T3-2   Q9H6T3-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPAP3: NX_Q9H6T3

Explore proteomics data for RPAP3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RPAP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001139547.1  NP_001139548.1  NP_078880.2  

    ENSEMBL proteins: 
     ENSP00000005386   ENSP00000401823   ENSP00000370024  

    RPAP3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RPAP3

     
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    Search eBioscience for ELISAs for RPAP3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TTC: Tetratricopeptide (TTC) repeat domain containing

    5 InterPro protein domains:
     IPR001440 TPR_1
     IPR011990 TPR-like_helical
     IPR025986 RPAP3-like_C
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9H6T3

    ProtoNet protein and cluster: Q9H6T3

    UniProtKB/Swiss-Prot: RPAP3_HUMAN, Q9H6T3
    Similarity: Belongs to the RPAP3 family
    Similarity: Contains 7 TPR repeats


    Find genes that share domains with RPAP3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPAP3_HUMAN, Q9H6T3
    Function: Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting
    that it is required to connect RNA polymerase II to regulators of protein complex formation

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18538670
         
    Find genes that share ontologies with RPAP3           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for RPAP3:
     Decreased Wnt reporter activit  G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPAP3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RPAP3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPAP3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPAP3

    miRNA
    Products:
        
    miRTarBase miRNAs that target RPAP3:
    hsa-mir-192-5p (MIRT026636)

    Block miRNA regulation of human, mouse, rat RPAP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RPAP3 (see all 19):
    hsa-miR-3146 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-548x hsa-miR-3143 hsa-miR-3148 hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidRPAP3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RPAP3

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    GenScript: all cDNA clones in your preferred vector (see all 3): RPAP3 (NM_024604)
    Sino Biological Human cDNA Clone for RPAP3
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPAP3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPAP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    cytosol2
    nucleus2
    plasma membrane2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPAP3
    Interactions:

        Search GeneGlobe Interaction Network for RPAP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RPAP3 (Q9H6T31, 2, 3 ENSP000000053864) via UniProtKB, MINT, STRING, and/or I2D (see all 68)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K3Q997592, 3MINT-48370 I2D: score=2 
    WDR92Q96MX61, 2, 3, ENSP000002951214EBI-356928,EBI-2434101 MINT-6551118 MINT-6551132 MINT-6551090 MINT-6551101 I2D: score=1 STRING: ENSP00000295121
    PFDN6O152123, ENSP000003637344I2D: score=1 STRING: ENSP00000363734
    ENSG00000206283O152123I2D: score=1 
    ENSG00000224782O152123I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPAP3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPAP3 gene (3 alternative transcripts): 
    NM_001146075.1  NM_001146076.1  NM_024604.2  

    Unigene Cluster for RPAP3:

    RNA polymerase II associated protein 3
    Hs.437855  [show with all ESTs]
    Unigene Representative Sequence: NM_024604
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000005386(uc001rpr.3 uc010slk.2 uc001rps.3) ENST00000548211
    ENST00000432584 ENST00000380650 ENST00000548296 ENST00000547706 ENST00000551293

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RPAP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RPAP3 (see all 19):
    hsa-miR-3146 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-548x hsa-miR-3143 hsa-miR-3148 hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidRPAP3 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat RPAP3
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): RPAP3 (NM_024604)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPAP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPAP3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RPAP3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPAP3
      QuantiTect SYBR Green Assays in human, mouse, rat RPAP3
      QuantiFast Probe-based Assays in human, mouse, rat RPAP3

    Additional mRNA sequence: 

    AK025561.1 AK299465.1 BC003680.1 BC056415.1 

    8 DOTS entries:

    DT.313903  DT.91714060  DT.92424072  DT.101982708  DT.92025804  DT.40110545  DT.95174301  DT.99949739 

    Selected AceView cDNA sequences (see all 171):

    AI631826 AI370682 F12403 AI089506 AA314382 W15386 BX644109 BP363461 
    AA837273 AI690479 AW168178 BX490334 AA830542 BQ287918 NM_024604 AI568309 
    BC003680 AA809324 AK025561 AA292128 AA594583 CF528698 BE550565 BM759526 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RPAP3    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                    -                       -                                                                           
    SP2:                    -                       -                                         -                                 
    SP3:                                                                                                                        
    SP4:                                                                                                                        


    ECgene alternative splicing isoforms for RPAP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPAP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTTTACAT
    RPAP3 Expression
    About this image


    RPAP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    RPAP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPAP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.437855
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPAP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RPAP3 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpap31 , 5 RNA polymerase II associated protein 31, 5 80.29(n)1
    79.64(a)1
      15 (53.54 cM)5
    719191  NM_028003.21  NP_082279.11 
     976751055 
    chicken
    (Gallus gallus)
    Aves RPAP31 RNA polymerase II associated protein 3 71.98(n)
    65.85(a)
      417811  NM_001006231.1  NP_001006231.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPAP36
    RNA polymerase II associated protein 3
    58(a)
    1 ↔ 1
    5(52935751-52964523)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.48282 Xenopus laevis transcribed sequence with weak similarity more 75.9(n)    BX844157.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc561782 hypothetical protein MGC56178 74.44(n)   393173  BC045972.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta spag1 spaghetti 43.68(n)
    32.63(a)
      43958  NM_079925.2  NP_524664.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SGT26
    Glutamine-rich cytoplasmic protein that serves as ...
    20(a)
    1 → many
    XV(338938-339978) YOR007C
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G564401 AT1G56440 46.65(n)
    35.44(a)
      842097  NM_104522.3  NP_176039.2 
    rice
    (Oryza sativa)
    Liliopsida Os05g01299001 Os05g0129900 48.58(n)
    37.58(a)
      4337703  NM_001061083.1  NP_001054548.1 


    ENSEMBL Gene Tree for RPAP3 (if available)
    TreeFam Gene Tree for RPAP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPAP3 gene
    SGTB2  TTC122  SGTA2  

    Find genes that share paralogs with RPAP3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPAP3 (see all 880)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1819762181,2
    --48055218(+) ATTCAC/TTCAAT 3 -- ds50010--------
    rs9483941,2
    C,F,A,H--48055232(-) tgggtA/GtaaGT 3 -- ds500119Minor allele frequency- G:0.16NS EA NA WA 2342
    rs1852096551,2
    --48055404(+) TTTTTA/TAAAAT 3 -- ds50010--------
    rs1467340211,2
    --48055422(+) CTATAC/GTAAAT 3 -- ds50010--------
    rs1403250111,2
    --48055434(+) TTGTGA/TTCTGT 3 -- ds50010--------
    rs1504328501,2
    --48055449(+) CTTCAA/GTTAAC 3 -- ds50010--------
    rs1174773801,2
    C,F--48055620(+) AGAATG/AACAAT 3 -- ds50011Minor allele frequency- A:0.03EA 120
    rs1452252371,2
    C--48055685(+) CCATTC/TGGGTT 3 -- ds50010--------
    rs123153561,2
    C,F,H--48055686(+) cattcG/Aggttg 3 -- ds500112Minor allele frequency- A:0.01NS EA NA WA 1730
    rs12330421,2
    C,F,H--48055705(-) GTTTGA/TTATTT 3 -- ds500111Minor allele frequency- T:0.25MN NS EA NA 848

    HapMap Linkage Disequilibrium report for RPAP3 (48055715 - 48099844 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RPAP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv695CNV Loss18451855
    nsv518487CNV Loss19592680
    nsv899058CNV Gain21882294
    esv2751101CNV Gain17911159
    nsv517899CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPAP3
    DNA2.0 Custom Variant and Variant Library Synthesis for RPAP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611477    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RPAP3:
    Malaria

    Find genes that share disorders with RPAP3           About GenesLikeMe


    Export disorders for RPAP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPAP3 gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with RPAP3)
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    1. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1, 2, 3 Jeronimo C.... Coulombe B. (Mol. Cell 2007)
    2. The F-box protein FBXO25 promotes the proteasome-dependent degradation of ELK-1 protein. (PubMed id 23940030)1 Teixeira F.R....Gomes M.D. (J. Biol. Chem. 2013)
    3. RPAP3 splicing variant isoform 1 interacts with PIH1D1 to compose R2TP complex for cell survival. (PubMed id 23159623)1 Yoshida M....Kamisaki Y. (Biochem. Biophys. Res. Commun. 2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. PIDD orchestrates translesion DNA synthesis in response to UV irradiation. (PubMed id 21415862)1 Logette E....Tschopp J. (Cell Death Differ. 2011)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79657 HGNC: 26151 AceView: FLJ21908 Ensembl:ENSG00000005175 euGenes: HUgn79657
    ECgene: RPAP3 H-InvDB: RPAP3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPAP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPAP3 gene:
    Search GeneIP for patents involving RPAP3

    GeneCards and IP:
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