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RPAP2 Gene

protein-coding   GIFtS: 45
GCID: GC01P092764

RNA Polymerase II Associated Protein 2

(Previous name: chromosome 1 open reading frame 82)
(Previous symbol: C1orf82)
  Search for RPAP2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RNA Polymerase II Associated Protein 21 2
C1orf821 2 3 5
RNA Polymerase II-Associated Protein 22 3
Chromosome 1 Open Reading Frame 821
Putative RNA Polymerase II Subunit B1 CTD Phosphatase RPAP22
EC 3.1.3.163

External Ids:    HGNC: 257911   Entrez Gene: 798712   Ensembl: ENSG000001224847   OMIM: 6114765   UniProtKB: Q8IXW53   

Export aliases for RPAP2 gene to outside databases

Previous GC identifers: GC01P092537 GC01P090884


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RPAP2 Gene:
RPAP2 (RNA polymerase II associated protein 2) is a protein-coding gene. GO annotations related to this gene include CTD phosphatase activity.

UniProtKB/Swiss-Prot: RPAP2_HUMAN, Q8IXW5
Function: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes.
Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA
polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting
transcription of snRNA genes

Gene Wiki entry for RPAP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RPAP2 gene promoter:
         AhR   Nkx3-1   Nkx3-1 v4   AML1a   Pax-2   Pax-2a   Nkx3-1 v1   Arnt   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRPAP2 promoter sequence
   Search Chromatin IP Primers for RPAP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RPAP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22.1   Ensembl cytogenetic band:  1p22.1   HGNC cytogenetic band: 1p22.1

RPAP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPAP2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P092764:  view genomic region     (about GC identifiers)

Start:
92,764,522 bp from pter      End:
92,867,613 bp from pter
Size:
103,092 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RPAP2_HUMAN, Q8IXW5 (See protein sequence)
Recommended Name: Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2  
Size: 612 amino acids; 69509 Da
Subunit: Associates with the RNA polymerase II complex. Interacts with transcribing RNA polymerase II
phosphorylated on 'Ser-7' on CTD
Secondary accessions: C9JKB5 Q49AS7 Q9H8Y2
Alternative splicing: 2 isoforms:  Q8IXW5-1   Q8IXW5-2   (Ref.3 (AAH31070) sequence is in conflict in position: 584:S->N)

Explore the universe of human proteins at neXtProt for RPAP2: NX_Q8IXW5

Explore proteomics data for RPAP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RPAP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079089.2  
    ENSEMBL proteins: 
     ENSP00000476948  

    RPAP2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007308 DUF408

    Graphical View of Domain Structure for InterPro Entry Q8IXW5

    ProtoNet protein and cluster: Q8IXW5

    UniProtKB/Swiss-Prot: RPAP2_HUMAN, Q8IXW5
    Domain: The RTR1-type zinc finger mediates interactions with RNA polymerase II complex subunits (PubMed:22137580)
    Similarity: Belongs to the RPAP2 family
    Similarity: Contains 1 RTR1-type zinc finger


    Find genes that share domains with RPAP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPAP2_HUMAN, Q8IXW5
    Function: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes.
    Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA
    polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting
    transcription of snRNA genes
    Catalytic activity: [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate

         Enzyme Number (IUBMB): EC 3.1.3.161

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008420CTD phosphatase activity IMP--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with RPAP2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RPAP2:
     Increased S DNA content  Lamellipodia cells 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rpap2):
     mortality/aging 

    Find genes that share phenotypes with RPAP2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RPAP2
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    miRNA
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    miRTarBase miRNAs that target RPAP2:
    hsa-mir-192-5p (MIRT026597), hsa-mir-183-5p (MIRT047058), hsa-mir-215-5p (MIRT024555)

    Block miRNA regulation of human, mouse, rat RPAP2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RPAP2 (see all 10):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-101* hsa-miR-452* hsa-miR-192 hsa-miR-432 hsa-miR-374a* hsa-miR-4279
    SwitchGear 3'UTR luciferase reporter plasmidRPAP2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RPAP2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPAP2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RPAP2_HUMAN, Q8IXW5: Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent
    manner
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0016591DNA-directed RNA polymerase II, holoenzyme IDA--

    Find genes that share ontologies with RPAP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RPAP2
    Interactions:

        Search GeneGlobe Interaction Network for RPAP2

    Selected Interacting proteins for RPAP2 (Q8IXW53) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206268P186153I2D: score=1 
    ENSG00000206357P186153I2D: score=1 
    ENSG00000229363P186153I2D: score=1 
    ENSG00000231044P186153I2D: score=1 
    ENSG00000233801P186153I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009301snRNA transcription IMP--
    GO:0070940dephosphorylation of RNA polymerase II C-terminal domain IMP--

    Find genes that share ontologies with RPAP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RPAP2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RPAP2 gene: 
    NM_024813.2  

    Unigene Cluster for RPAP2:

    RNA polymerase II associated protein 2
    Hs.444421  [show with all ESTs]
    Unigene Representative Sequence: NM_024813
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000610020 ENST00000484158 ENST00000477322
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate RPAP2 (see all 10):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-101* hsa-miR-452* hsa-miR-192 hsa-miR-432 hsa-miR-374a* hsa-miR-4279
    SwitchGear 3'UTR luciferase reporter plasmidRPAP2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RPAP2
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    OriGene qSTAR qPCR primer pairs in human, mouse for RPAP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RPAP2
      QuantiTect SYBR Green Assays in human, mouse, rat RPAP2
      QuantiFast Probe-based Assays in human, mouse, rat RPAP2

    Additional mRNA sequence: 

    AK023212.1 AK225054.1 BC031070.1 BC039014.1 

    6 DOTS entries:

    DT.113395  DT.100816781  DT.100816778  DT.92421623  DT.97832147  DT.100020492 

    Selected AceView cDNA sequences (see all 73):

    BP369593 BX112953 BM559559 CN479576 BM672068 AI580293 BU633786 AA770422 
    AA227530 CB243643 BC039014 BC031070 NM_024813 AK023212 BM546733 AI198962 
    CR613797 BM971680 W37280 BX419669 AA243738 BE869363 AI188563 BX448624 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RPAP2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                                -                                                               
    SP2:                    -                                                                           
    SP3:                                                                                                
    SP4:                                                                                                


    ECgene alternative splicing isoforms for RPAP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RPAP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGTCTGGT
    RPAP2 Expression
    About this image

    RPAP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RPAP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444421
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RPAP2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpap21 , 5 RNA polymerase II associated protein 21, 5 77.65(n)1
    70.68(a)1
      5 (52.23 cM)5
    2315711  NM_144911.21  NP_659160.21 
     1075973735 
    chicken
    (Gallus gallus)
    Aves RPAP21 RNA polymerase II associated protein 2 64.34(n)
    57.48(a)
      424501  XM_004936605.1  XP_004936662.1 
    lizard
    (Anolis carolinensis)
    Reptilia RPAP26
    RNA polymerase II associated protein 2
    47(a)
    1 ↔ 1
    4(93758276-93835245)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.160312 Transcribed sequence with weak similarity to protein more 74.17(n)    AL970899.2 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.257012 Transcribed sequence with weak similarity to protein more 73.44(n)    BQ258464.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG341836
    --
    50(a)
    1 ↔ 1
    2L(9890061-9890772)


    ENSEMBL Gene Tree for RPAP2 (if available)
    TreeFam Gene Tree for RPAP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RPAP2 gene

    Find genes that share paralogs with RPAP2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for RPAP2
    PGOHUM00000238571


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RPAP2 (see all 1425)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1874005871,2
    --92766750(+) GAAAAC/TAGAAA 1 -- int10--------
    rs66954751,2
    C,F,A,H--92766781(+) TATGCC/TGGTGA 1 -- int19Minor allele frequency- T:0.12NS EA NA WA CSA 539
    rs66040881,2
    C,F,A--92766848(+) CCAGTC/TTGAGC 1 -- int112Minor allele frequency- T:0.21NA WA CSA EA 377
    rs1488128461,2
    F--92767099(+) ATTGTT/CGAACA 2 /V syn11Minor allele frequency- C:0.00NA 4476
    rs1433949001,2
    C,F--92767132(+) GAAGAG/CTTCCT 2 /D /E mis11Minor allele frequency- C:0.00NA 4408
    rs66040891,2
    C,F,H--92767292(+) CATTTT/AAAAAT 1 -- int117Minor allele frequency- A:0.07NS EA NA WA CSA 769
    rs120863541,2
    C,F,H--92767358(+) AAGTAC/TGTAAC 1 -- int113Minor allele frequency- T:0.10NS EA NA WA CSA 1314
    rs1163342571,2
    C,F--92767507(+) CATCAC/TATACT 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1911693601,2
    --92767550(+) TTAAAA/CAGCAA 1 -- int10--------
    rs1833004771,2
    --92767685(+) ATACAA/GAATTA 1 -- int10--------

    HapMap Linkage Disequilibrium report for RPAP2 (92764522 - 92867613 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RPAP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2714684CNV Deletion23290073
    nsv870667CNV Loss21882294
    dgv266n71CNV Loss21882294
    nsv871508CNV Gain21882294
    nsv830592CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RPAP2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611476    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RPAP2:
    Acute pancreatitis

    Find genes that share disorders with RPAP2           About GenesLikeMe


    Export disorders for RPAP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RPAP2 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with RPAP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1, 2, 3 Jeronimo C.... Coulombe B. (Mol. Cell 2007)
    2. Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes. (PubMed id 22137580)1, 2 Egloff S.... Murphy S. (Mol. Cell 2012)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. (PubMed id 22231121)2 Ni Z.... Greenblatt J.F. (Transcription 2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    10. Defining the human deubiquitinating enzyme interaction landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (Cell 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79871 HGNC: 25791 AceView: FLJ13150 Ensembl:ENSG00000122484 euGenes: HUgn79871
    ECgene: RPAP2 H-InvDB: RPAP2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RPAP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RPAP2 gene:
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