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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RPAIN Gene

protein-coding   GIFtS: 47
GCID: GC17P005263

RPA Interacting Protein

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
RPA Interacting Protein1 2     RAP Interaction Protein2
RIP2 3     RPA-Interacting Protein2
HRIP2     hRIP3
Nuclear Transporter2     

External Ids:    HGNC: 286411   Entrez Gene: 842682   Ensembl: ENSG000001291977   UniProtKB: Q86UA63   
ORGUL members:         
NONCODE14:n407967 n407963 n407966 n407968 n407964 see all 7      

Export aliases for RPAIN gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RPAIN Gene: 
RPAIN (RPA interacting protein) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with RPAIN include patent ductus arteriosus, and protein s deficiency. GO annotations related to this gene include protein complex binding and metal ion binding.

UniProtKB/Swiss-Prot: RIP_HUMAN, Q86UA6
Function: Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta.
Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby
participating in RPA function in DNA metabolism

Gene Wiki entry for RPAIN Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RPAIN gene promoter:
         AhR   AP-1   CUTL1   Arnt   E47   HEN1   Pax-3   POU2F1   POU2F1a   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RPAIN promoter sequence
   Search SABiosciences Chromatin IP Primers for RPAIN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RPAIN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.2   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.2

RPAIN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RPAIN gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P005263:  view genomic region     (about GC identifiers)

Start:
5,322,961 bp from pter      End:
5,336,340 bp from pter
Size:
13,380 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for RPAIN

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RIP_HUMAN, Q86UA6 (See protein sequence)
Recommended Name: RPA-interacting protein  
Size: 219 amino acids; 24784 Da
Subunit: Interacts with the RPA1 subunit of RPA complex
Subcellular location: Isoform 1: Cytoplasm. Nucleus
Subcellular location: Isoform 2: Nucleus, PML body
Secondary accessions: B4DI36 B4DTX7 E9PES3 J3KNH8 Q4G2Y0 Q4G2Y5 Q4G2Y8 Q6B4V9 Q6B4W0 Q6B4W1
Q6B4W4 Q86X49 Q9BT00
Alternative splicing: 9 isoforms:  Q86UA6-1   Q86UA6-2   Q86UA6-3   Q86UA6-4   Q86UA6-5   Q86UA6-6   Q86UA6-7   Q86UA6-8   
Q86UA6-9   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RPAIN: NX_Q86UA6

Explore proteomics data for RPAIN at MOPED 

Post-translational modifications:

  • UniProtKB: Isoform 2 is sumoylated. Sumoylation is required for localization in the nuclear PML body and transport of RPA
    complex in PML body. Upon UV irradiation and during S phase, it is desumoylated, releasing RPA complex that is
    translocated to sites of DNA damage. Sumoylation takes place at different Lys residues
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86UA6

  • RPAIN Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RPAIN Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001028174.2  NP_001153715.1  NP_001153716.1  NP_001153718.1  NP_001153738.1  

    ENSEMBL proteins: 
     ENSP00000439939   ENSP00000460162   ENSP00000458699   ENSP00000458218   ENSP00000370606  
     ENSP00000446453   ENSP00000370605   ENSP00000315069   ENSP00000460354   ENSP00000385814  
     ENSP00000467178  

    Human Recombinant Protein Products for RPAIN: 
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    Novus Biologicals RPAIN Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RPAIN 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0016605PML body IEA--

    RPAIN for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for RPAIN


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q86UA6

    UniProtKB/Swiss-Prot: RIP_HUMAN, Q86UA6
    Similarity: Contains 1 RIP-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RIP_HUMAN, Q86UA6
    Function: Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta.
    Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby
    participating in RPA function in DNA metabolism

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032403protein complex binding IPI16135809
    GO:0046872metal ion binding IEA--
         
    RPAIN for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RPAIN 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RPAIN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RPAIN 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RPAIN 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RPAIN
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate RPAIN:
    hsa-miR-203 hsa-miR-3149 hsa-miR-3163 hsa-miR-96*
    SwitchGear 3'UTR luciferase reporter plasmidRPAIN 3' UTR sequence
    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPAIN


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RPAIN

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for RPAIN (ENSP000003706064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADH6ENSP000003783594STRING: ENSP00000378359
    CDCA5ENSP000002755174STRING: ENSP00000275517
    CYP17A1ENSP000003589034STRING: ENSP00000358903
    GSTA1ENSP000003356204STRING: ENSP00000335620
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006261DNA-dependent DNA replication IPI16135809
    GO:0006281DNA repair IPI16135809
    GO:0006310DNA recombination IPI16135809
    GO:0006606protein import into nucleus IDA16135809
    GO:0009411response to UV IDA16135809

    RPAIN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RPAIN (RIP)

    Search CenterWatch for drugs/clinical trials and news about RPAIN / RIP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RPAIN gene (7 alternative transcripts): 
    NM_001160267.1  NM_032308.1  NM_001033002.3  NM_001160243.1  NM_001160244.1  NM_001160246.1  NM_001160266.1  

    Unigene Cluster for RPAIN:

    RPA interacting protein
    Hs.462086  [show with all ESTs]
    Unigene Representative Sequence: NM_001160243
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000536255 ENST00000573577(uc002gbu.2 uc002gbw.2) ENST00000571558(uc002gbs.2)
    ENST00000575599(uc002gbv.2) ENST00000381209(uc002gbq.2) ENST00000571043
    ENST00000571613 ENST00000539417(uc002gbr.2) ENST00000381208(uc010vtb.1 uc002gbt.2)
    ENST00000327154 ENST00000572174 ENST00000570883 ENST00000575112 ENST00000575711
    ENST00000405578 ENST00000573126 ENST00000574003
    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate RPAIN:
    hsa-miR-203 hsa-miR-3149 hsa-miR-3163 hsa-miR-96*
    SwitchGear 3'UTR luciferase reporter plasmidRPAIN 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RPAIN
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RPAIN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RPAIN
    Sirion Biotech Customized lentivirus for stable overexpression of RPAIN 
                         Customized lentivirus expression plasmids for stable overexpression of RPAIN 
    Primer
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    OriGene qPCR primer pairs and template standards for RPAIN
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RPAIN
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RPAIN

    Additional mRNA sequence: 

    AK226044.1 AK295394.1 AK300409.1 AY680654.1 AY680655.1 AY680660.1 AY775314.1 AY775316.1 
    AY775321.1 BC013831.1 BC046349.1 BC051849.2 NR_027679.1 NR_027682.1 NR_027683.1 NR_027684.1 
    NR_027685.1 

    24/35 DOTS entries (see all 35):

    DT.100880014  DT.87017606  DT.95085723  DT.95085732  DT.100880019  DT.91771986  DT.100880015  DT.95085802 
    DT.100739616  DT.100880029  DT.101985488  DT.120977882  DT.95085781  DT.100880026  DT.100880017  DT.40116686 
    DT.97864145  DT.40217418  DT.219474  DT.120977936  DT.100880016  DT.120977905  DT.95085779  DT.120977769 

    24/309 AceView cDNA sequences (see all 309):

    CR605756 BE856361 AI866522 AA430402 AA774634 AA628365 AI630400 AA281392 
    AA886406 NM_032308 AI741768 BX362900 BF432700 W79170 CA945044 BC004451 
    BQ893900 AA576306 BC046349 CD676410 AA429252 AK096001 CR612912 AI167203 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RPAIN    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b
    SP1:                          -           -                           
    SP2:                          -           -           -               
    SP3:                          -           -     -                     
    SP4:                          -                                       
    SP5:                                                                  


    ECgene alternative splicing isoforms for RPAIN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RPAIN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATACAAAA
    RPAIN Expression
    About this image


    See RPAIN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RPAIN

    SOURCE GeneReport for Unigene cluster: Hs.462086

    UniProtKB/Swiss-Prot: RIP_HUMAN, Q86UA6
    Tissue specificity: Widely expressed. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain, heart,
    leukocytes, colon, intestine, ovary, testis, prostate, thymus and spleen

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RPAIN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for RPAIN gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rpain1 , 5 RPA interacting protein1, 5 78.54(n)1
    73.52(a)1
      11 (43.21 cM)5
    697231  NM_027186.21  NP_081462.11 
     709702135 
    chicken
    (Gallus gallus)
    Aves RPAIN1 RPA interacting protein 63.05(n)
    57.14(a)
      417500  XM_415749.3  XP_415749.2 
    lizard
    (Anolis carolinensis)
    Reptilia RPAIN6
    Uncharacterized protein
    42(a)
    1 ↔ 1
    GL344757.1(18233-20572)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1532511 zgc:153251 53.37(n)
    43.27(a)
      751671  NM_001045388.1  NP_001038853.1 


    ENSEMBL Gene Tree for RPAIN (if available)
    TreeFam Gene Tree for RPAIN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/261 SNPs in RPAIN are shown (see all 261)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58190261,2
    C--5325262(+) accat-/GCCC  
            
    gcccg
    10 -- int10--------
    rs30661961,2
    C--5325263(+) GCCCG-/CCC   
      G
    /GCCC
    GCTAA
    10 -- int10--------
    rs30661991,2
    C--5325367(+) GAATC-/TCTT  
            
    TCTAA
    10 -- int10--------
    rs724732981,2
    C--5325370(+) TCTCT-/TTCT  
            
    AAAAA
    10 -- int10--------
    rs1862164201,2
    --5325589(+) TTTCAC/GCATTG 10 -- int10--------
    rs98954401,2
    C,F,A,H--5325643(+) AACACA/CCTGTG 10 -- int111Minor allele frequency- N:0.00EA NA CSA WA 581
    rs1442039371,2
    --5325786(+) GAGATG/TTGCAG 10 -- int10--------
    rs98939951,2
    C,F,H--5325788(+) GATTTG/ACAGAG 10 -- int115Minor allele frequency- A:0.08NS EA NA WA 2042
    rs98967351,2
    C,F,A,H--5325808(+) TTTTCA/CTGTGG 10 -- int122Minor allele frequency- C:0.42NS EA NA CSA WA 2487
    rs1913606421,2
    --5325858(+) TATATC/TGTCTC 10 -- int10--------

    HapMap Linkage Disequilibrium report for RPAIN (5322961 - 5336340 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RPAIN: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RPAIN
    DNA2.0 Custom Variant and Variant Library Synthesis for RPAIN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    6 diseases for RPAIN:    About MalaCards
    patent ductus arteriosus    protein s deficiency    hepatitis b    hepatitis
    cervicitis    prostatitis


    RPAIN for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for RPAIN gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 8.15 5 17210702 (1), 15572679 (1), 16507998 (1)
    tumors 0 1 15572679 (1)

    Genetic Association Database (GAD): RPAIN
    Human Genome Epidemiology (HuGE) Navigator: RPAIN (2 documents)

    Export disorders for RPAIN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RPAIN gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with RPAIN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification, expression pattern, and subcellular location of human RIP isoforms. (PubMed id 16008515)1, 2, 3, 9 Chen J.Z....Xue J.L. (2005)
    2. Sumoylation of the novel protein hRIPbeta is involved in replication protein A deposition in PML nuclear bodies. (PubMed id 16135809)1, 2, 3, 9 Park J.... Choe J. (2005)
    3. Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370)1, 4 Dagle J.M....Murray J.C. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Elevated level of human RPA interacting protein a (hRI Pa) in cervical tumor cells is involved in cell proliferation through regulating RPA transport. (PubMed id 23010595)1 Namkoong S....Park J. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Translational regulation of HIV-1 replication by HIV-1 Rev cellular cofactors Sam68, eIF5A, hRIP, and DDX3. (PubMed id 21360055)1 Liu J....He J.J. (2011)
    9. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    10. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84268 HGNC: 28641 AceView: RIP Ensembl:ENSG00000129197 euGenes: HUgn84268
    ECgene: RPAIN H-InvDB: RPAIN

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RPAIN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RPAIN gene:
    Search GeneIP for patents involving RPAIN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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