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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RP9 Gene

protein-coding   GIFtS: 53
GCID: GC07M033100

Retinitis Pigmentosa 9 (Autosomal Dominant)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Retinitis Pigmentosa 9 (Autosomal Dominant)1 2
Pim-1 Kinase Associated Protein1 2
Pim-1-Associated Protein2 3
PAP-12 3
Retinitis Pigmentosa 9 Protein2

External Ids:    HGNC: 102881   Entrez Gene: 61002   Ensembl: ENSG000001646107   OMIM: 6073315   UniProtKB: Q8TA863   

Export aliases for RP9 gene to outside databases

Previous GC identifers: GC07U990086 GC07M032877 GC07M032907 GC07M033013


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RP9 Gene:
The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a
serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and
has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this
protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis
pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb
distal to this gene. (provided by RefSeq, Sep 2009)

GeneCards Summary for RP9 Gene: 
RP9 (retinitis pigmentosa 9 (autosomal dominant)) is a protein-coding gene. Diseases associated with RP9 include cystoid macular dystrophy, and rp9-related retinitis pigmentosa. GO annotations related to this gene include zinc ion binding and nucleic acid binding.

UniProtKB/Swiss-Prot: RP9_HUMAN, Q8TA86
Function: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in
association with PIM1 (By similarity)

Gene Wiki entry for RP9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RP9 gene promoter:
         FOXC1   GCNF-1   GCNF   c-Myb   CUTL1   GCNF-2   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRP9 promoter sequence
   Search SABiosciences Chromatin IP Primers for RP9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RP9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p14.3   Ensembl cytogenetic band:  7p14.3   HGNC cytogenetic band: 7p14.3

RP9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RP9 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M033100:  view genomic region     (about GC identifiers)

Start:
33,134,409 bp from pter      End:
33,149,013 bp from pter
Size:
14,605 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 33,178,937-33,193,530     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RP9_HUMAN, Q8TA86 (See protein sequence)
Recommended Name: Retinitis pigmentosa 9 protein  
Size: 221 amino acids; 26107 Da
Subunit: Binds to PIM1 (By similarity). Binds to ZNHIT4
Subcellular location: Nucleus (By similarity)

Explore the universe of human proteins at neXtProt for RP9: NX_Q8TA86

Explore proteomics data for RP9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TA86

  • RP9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RP9 Protein Expression
    REFSEQ proteins: NP_976033.1  
    ENSEMBL proteins: 
     ENSP00000297157   ENSP00000411577  

    Human Recombinant Protein Products for RP9: 
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    OriGene Custom MassSpec 
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    GenScript Custom Purified and Recombinant Proteins Services for RP9
    Novus Biologicals RP9 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for RP9
    Cloud-Clone Corp. Proteins for RP9 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005785signal recognition particle receptor complex IEA--

    RP9 for ontologies           About GeneDecksing



    RP9 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for RP9 

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    Cloud-Clone Corp. CLIAs for RP9


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR001878 Znf_CCHC

    Graphical View of Domain Structure for InterPro Entry Q8TA86

    ProtoNet protein and cluster: Q8TA86

    UniProtKB/Swiss-Prot: RP9_HUMAN, Q8TA86
    Similarity: Contains 1 CCHC-type zinc finger


    RP9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RP9_HUMAN, Q8TA86
    Function: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in
    association with PIM1 (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005515protein binding IPI15652350
    GO:0008270zinc ion binding IEA--
         
    RP9 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RP9:
     Decreased viability with pacli  High actin ratio cells  Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RP9 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RP9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RP9 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RP9 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RP9
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RP9:
    hsa-miR-1253
    SwitchGear 3'UTR luciferase reporter plasmidRP9 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of RP9

    Clone
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    OriGene ORF clones in mouse, rat for RP9
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    GenScript: all cDNA clones in your preferred vector: RP9 (NM_203288)
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                         Customized lentivirus expression plasmids for stable overexpression of RP9 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RP9


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RP9

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for RP9 (Q8TA863 ENSP000002971574) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CIR1Q86X953, ENSP000003397234I2D: score=1 STRING: ENSP00000339723
    SRSF1Q079553, ENSP000002589624I2D: score=1 STRING: ENSP00000258962
    U2AF1Q010813, ENSP000002915524I2D: score=2 STRING: ENSP00000291552
    INO80BQ9C0863, ENSP000002333314I2D: score=1 STRING: ENSP00000233331
    SUMO2ENSP000004059654STRING: ENSP00000405965
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008380RNA splicing TAS15652350

    RP9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RP9 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RP9

    1 Novoseek inferred chemical compound relationship for RP9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    serine 39.9 1 10931201 (1)

    Search CenterWatch for drugs/clinical trials and news about RP9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RP9 gene: 
    NM_203288.1  

    Unigene Cluster for RP9:

    Retinitis pigmentosa 9 (autosomal dominant)
    Hs.326805  [show with all ESTs]
    Unigene Representative Sequence: NM_203288
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297157(uc003tdm.3) ENST00000448915 ENST00000474370 ENST00000492391

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RP9
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RP9:
    hsa-miR-1253
    SwitchGear 3'UTR luciferase reporter plasmidRP9 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RP9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RP9
    Clone
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    GenScript: all cDNA clones in your preferred vector: RP9 (NM_203288)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RP9
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                         Customized lentivirus expression plasmids for stable overexpression of RP9 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RP9
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RP9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RP9

    Additional mRNA sequence: BC025928.1 

    13 DOTS entries:

    DT.313370  DT.121048924  DT.121048770  DT.121048710  DT.86849308  DT.91640984  DT.40127082  DT.100045510 
    DT.121048802  DT.121048849  DT.95165610  DT.100673832  DT.92427536 

    24/210 AceView cDNA sequences (see all 210):

    BQ188360 BU736741 AF007887 BF940281 BC036907 AI492167 AA164195 BF438270 
    BM677345 BF588527 AI333133 AW140134 AI802000 BE549502 BE671844 AI147051 
    AA503367 AI805270 AI299005 AI369454 CA395366 CK299840 AI221290 AI559377 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RP9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTTTACGAT
    RP9 Expression
    About this image


    See RP9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RP9

    SOURCE GeneReport for Unigene cluster: Hs.326805

    UniProtKB/Swiss-Prot: RP9_HUMAN, Q8TA86
    Tissue specificity: Appears to be expressed in a wide range of tissues

        SABiosciences Custom PCR Arrays for RP9
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RP9
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RP9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for RP9 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rp91 , 5 retinitis pigmentosa 9 (human)1, 5 87.72(n)1
    92.82(a)1
      9 (9.16 cM)5
    559341  NM_018739.21  NP_061209.11 
     224483115 
    chicken
    (Gallus gallus)
    Aves RP91 retinitis pigmentosa 9 (autosomal dominant) 74.84(n)
    80.88(a)
      420747  XM_418845.3  XP_418845.1 
    lizard
    (Anolis carolinensis)
    Reptilia RP96
    Uncharacterized protein
    68(a)
    1 ↔ 1
    6(45311947-45328042)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003306791 retinitis pigmentosa 9 protein homolog 66.18(n)
    72.2(a)
      100330679  XM_002665572.1  XP_002665618.1 


    ENSEMBL Gene Tree for RP9 (if available)
    TreeFam Gene Tree for RP9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RP9 gene

    RP9 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for RP9
    PGOHUM00000239986 PGOHUM00000232642


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/332 SNPs in RP9 are shown (see all 332)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0172524
    Retinitis pigmentosa 9 (RP9)4--see VAR_0172522 H L mis40--------
    VAR_0172534
    Retinitis pigmentosa 9 (RP9)4--see VAR_0172532 D G mis40--------
    rs1048940391,2
    Cpathogenic133107558(-) CTCAGA/GTGAAG 2 D G mis10--------
    rs1048940371,2
    Cpathogenic133108717(-) GGCACA/TTGAAG 2 H L mis10--------
    rs1920001801,2
    --33106574(+) GTATAC/TGGGAA 1 -- int10--------
    rs1473779571,2
    --33106592(+) GTAGGC/GAACAG 1 -- int10--------
    rs1837017491,2
    --33106627(+) AGGGAC/TTTGGG 1 -- int10--------
    rs1139962651,2
    F--33106638(+) CATCCA/CCGGAT 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1395634231,2
    --33106879(+) AGAGTC/TTTCAT 1 -- int10--------
    rs1885748541,2
    C--33106935(+) TACTTA/TTGTAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for RP9 (33134409 - 33149013 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RP9:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv1127e201CNV Deletion23290073
    nsv436907CNV Insertion17901297
    nsv508450CNV Loss20534489
    nsv520406CNV Gain19592680
    nsv830942CNV Gain17160897
    dgv808n27CNV Gain19166990


    Human Gene Mutation Database (HGMD): RP9
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RP9
    DNA2.0 Custom Variant and Variant Library Synthesis for RP9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607331   
    OMIM disorders: 180104  
    UniProtKB/Swiss-Prot: RP9_HUMAN, Q8TA86
  • Retinitis pigmentosa 9 (RP9) [MIM:180104]: A retinal dystrophy belonging to the group of pigmentary
    retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination
    and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically
    have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose
    their far peripheral visual field and eventually central vision as well. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 12 diseases for RP9:    About MalaCards
    cystoid macular dystrophy    rp9-related retinitis pigmentosa    japanese encephalitis    retinitis pigmentosa 9
    histoplasmosis    retinitis pigmentosa    retinal disease    retinitis
    rhyns syndrome    night blindness    blindness    encephalitis

    1 disease from the University of Copenhagen DISEASES database for RP9:
    Retinitis pigmentosa

    RP9 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for RP9 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinitis pigmentosa 61.7 5 15474994 (2), 15652350 (1)

    Genetic Association Database (GAD): RP9
    Human Genome Epidemiology (HuGE) Navigator: RP9 (1 document)

    Export disorders for RP9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RP9 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with RP9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel nucleolar protein, PAPA-1, induces growth arrest as a result of cell cycle arrest at the G1 phase. (PubMed id 15556297)1, 2, 9 Kuroda T.S....Iguchi-Ariga S.M.M. (2004)
    2. Simultaneous Mutation Detection in 90 Retinal Disease Genes in Multiple Patients Using a Custom-designed 300-kb Retinal Resequencing Chip. (PubMed id 20801516)1, 4 Booij J.C....Florijn R.J. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa. (PubMed id 12032732)1, 2 Keen T.J.... Inglehearn C.F. (2002)
    5. A new locus for autosomal dominant retinitis pigmentosa on chromosome 7p. (PubMed id 8513323)1, 3 Inglehearn C.F....Bird A.C. (1993)
    6. PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor. (PubMed id 15474994)1, 9 Maita H....Iguchi-Ariga S.M. (2004)
    7. PAP-1, a novel target protein of phosphorylation by pim-1 kinase. (PubMed id 10931201)1, 9 Maita H....Iguchi-Ariga S.M. (2000)
    8. CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing. (PubMed id 15652350)1, 9 Maita H....Iguchi-Ariga S.M. (2005)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6100 HGNC: 10288 AceView: RP9 Ensembl:ENSG00000164610 euGenes: HUgn6100
    ECgene: RP9 H-InvDB: RP9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RP9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RP9 gene:
    Search GeneIP for patents involving RP9

    GeneCards and IP:
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