Aliases for RP9 Gene
External Ids for RP9 Gene
Previous GeneCards Identifiers for RP9 Gene
The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009]
GeneCards Summary for RP9 Gene
RP9 (Retinitis Pigmentosa 9 (Autosomal Dominant)) is a Protein Coding gene. Diseases associated with RP9 include retinitis pigmentosa 9 and rp9-related retinitis pigmentosa. Among its related pathways are mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleic acid binding and poly(A) RNA binding.
UniProtKB/Swiss-Prot for RP9 Gene
Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 (By similarity).