Aliases for RP1L1 Gene
Aliases for RP1L1 Gene
External Ids for RP1L1 Gene
- HGNC: 15946
- Entrez Gene: 94137
- Ensembl: ENSG00000183638
- OMIM: 608581
- UniProtKB: Q8IWN7
Previous GeneCards Identifiers for RP1L1 Gene
- GC00U991063
- GC08U900030
- GC08M010335
- GC08M010501
- GC08M009394
Summaries for RP1L1 Gene
-
This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, and two C-terminal large repetitive regions, both of which contain a high percentage of glutamine and glutamic acid residues. This protein is a retinal-specific protein. Its exact length varies among individuals due to the presence of a 16aa repeat in the first C-terminal repetitive region. The 16aa repeat is encoded by the highly polymorphic 48-bp repeat, and 1-6 copies of the 16aa repeat have been identified in normal individuals. The current reference sequence shown here has a single copy of the 16aa repeat. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Mutations in this gene cause occult macular dystrophy (OMD). [provided by RefSeq, Sep 2010]
GeneCards Summary for RP1L1 Gene
RP1L1 (RP1 Like 1) is a Protein Coding gene. Diseases associated with RP1L1 include Occult Macular Dystrophy and Retinitis Pigmentosa 1. An important paralog of this gene is RP1.
UniProtKB/Swiss-Prot for RP1L1 Gene
-
Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity).
No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RP1L1 Gene
Genomics for RP1L1 Gene
Regulatory Elements for RP1L1 Gene
Enhancers for RP1L1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RP1L1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RP1L1 gene promoter:
Regulatory Element Products
Genomic Location for RP1L1 Gene
- Chromosome:
- 8
- Start:
- 10,606,349 bp from pter
- End:
- 10,712,187 bp from pter
- Size:
- 105,839 bases
- Orientation:
- Minus strand
Genomic View for RP1L1 Gene
Genes around RP1L1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p23.1 by Ensembl
- 8p23.1 by Entrez Gene
- 8p23.1 by HGNC
RP1L1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RP1L1 Gene
Proteins for RP1L1 Gene
-
Protein details for RP1L1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IWN7-RP1L1_HUMAN
- Recommended name:
- Retinitis pigmentosa 1-like 1 protein
- Protein Accession:
- Q8IWN7
- Q86SQ1
- Q8IWN8
- Q8IWN9
- Q8IWP0
- Q8IWP1
- Q8IWP2
Protein attributes for RP1L1 Gene
- Size:
- 2480 amino acids
- Molecular mass:
- 261207 Da
- Quaternary structure:
-
- Interacts with RP1; has a synergistic effect with RP1 in photoreceptor differentiation.
Protein Expression for RP1L1 Gene
Post-translational modifications for RP1L1 Gene
Other Protein References for RP1L1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for RP1L1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RP1L1
- Origene Custom Protein Services for RP1L1
- Search GeneTex for Proteins for RP1L1
Assay Products
No data available for DME Specific Peptides for RP1L1 Gene
Domains & Families for RP1L1 Gene
Gene Families for RP1L1 Gene
Protein Domains for RP1L1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RP1L1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IWN7UniProtKB/Swiss-Prot:
RP1L1_HUMAN :- The C-terminal part contains a large repetitive region which contains an unusually high percentage of glutamine, glycine and above all glutamic acid residues.
- Domain:
-
- The C-terminal part contains a large repetitive region which contains an unusually high percentage of glutamine, glycine and above all glutamic acid residues.
- Contains 2 doublecortin domains.
Function for RP1L1 Gene
Molecular function for RP1L1 Gene
- UniProtKB/Swiss-Prot Function:
- Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity).
Phenotypes for RP1L1 Gene
- MGI mutant phenotypes for RP1L1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RP1L1:
Animal Models for RP1L1 Gene
- MGI Knock Outs for RP1L1:
-
- Rp1l1 tm1Jnz
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RP1L1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for RP1L1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RP1L1 gene
- Search ViGene Biosciences for RP1L1
CRISPR Products
-
OriGene CRISPR knockouts for RP1L1
- GenScript: Design CRISPR guide RNA sequences for RP1L1
miRNA for RP1L1 Gene
- miRTarBase miRNAs that target RP1L1
miRNA Products
- Search ViGene Biosciences for RP1L1
Inhibitory RNA Products
- Origene RNAi, mouse_rna, siRNA, and shRNA products in human, mouse, rat for RP1L1
- Browse OriGene Inhibitory RNA Products For RP1L1
-
ViGene Biosciences ready-to-package AAV shRNAs for RP1L1 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for RP1L1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RP1L1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RP1L1
-
ViGene Biosciences adenoviral particle packaged cDNA for RP1L1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RP1L1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RP1L1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for RP1L1 Gene
Localization for RP1L1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RP1L1 Gene
- Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, photoreceptor outer segment. Note=Localized to the axoneme of outer segments and connecting cilia in rod photoreceptors. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytoskeleton | 4 |
| mitochondrion | 2 |
| nucleus | 2 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001750 | photoreceptor outer segment | ISS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005874 | microtubule | IEA | -- |
| GO:0005930 | axoneme | ISS | -- |
| GO:0032391 | photoreceptor connecting cilium | ISS | -- |
Pathways & Interactions for RP1L1 Gene
No Data Available
Interacting Proteins for RP1L1 Gene
Selected Interacting proteins:
Q8IWN7-RP1L1_HUMAN
ENSP00000371923
for RP1L1 Gene via
MINT
STRING
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007601 | visual perception | IEA | -- |
| GO:0035082 | axoneme assembly | IBA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
| GO:0042461 | photoreceptor cell development | ISS | -- |
| GO:0045494 | photoreceptor cell maintenance | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for RP1L1 Gene
Transcripts for RP1L1 Gene
mRNA/cDNA for RP1L1 Gene
- (1) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (29) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RP1L1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RP1L1
- GenScript: Design CRISPR guide RNA sequences for RP1L1
miRNA Products
- Search ViGene Biosciences for RP1L1
Inhibitory RNA Products
- Origene RNAi, mouse_rna, siRNA, and shRNA products in human, mouse, rat for RP1L1
- Browse OriGene Inhibitory RNA Products For RP1L1
-
ViGene Biosciences ready-to-package AAV shRNAs for RP1L1 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for RP1L1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RP1L1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for RP1L1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Mature Rod Cells Outer Nuclear Layer
-
Neurons
- Mature Rod Cells Outer Nuclear Layer
mRNA differential expression in normal tissues according to GTEx for RP1L1 Gene
This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x5.5) and Skin - Not Sun Exposed (Suprapubic) (x4.2).
This gene is overexpressed in CD4 Tcells (21.4), Retina (16.3), Fetal Brain (14.2), and Heart (6.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RP1L1 Gene
NURSA nuclear receptor signaling pathways regulating expression of RP1L1 Gene:
RP1L1SOURCE GeneReport for Unigene cluster for RP1L1 Gene:
Hs.33538mRNA Expression by UniProt/SwissProt for RP1L1 Gene:
Q8IWN7-RP1L1_HUMAN
Tissue specificity:
Retinal-specific; expressed in photoreceptor.
Primer Products
-
OriGene qPCR primer pairs for RP1L1
Orthologs for RP1L1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RP1L1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | RP1L1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | RP1L1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC683404 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Rp1l1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | RP1L1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RP1L1 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | RP1L1 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | rp1l1 35 |
|
OneToMany | |
| RP1L1 (1 of 2) 35 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | F27C1.13 35 |
|
OneToMany |
- Species where no ortholog for RP1L1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for RP1L1 Gene
Variants for RP1L1 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for RP1L1 Gene
- RP1L1_HUMAN-Q8IWN7
- The exact length of RP1L1 is variable between individuals due to the presence of several length polymorphisms. The sequence shown here is that of allele RP1L1-6 and includes 8 repeats (from aa 1292-1422) with a length of 16 amino acids. The number of repeats is highly polymorphic and varies among different alleles, ranging from 3 to 8.
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_065126 | Occult macular dystrophy (OCMD) [MIM:613587] | ||||
| VAR_065127 | Occult macular dystrophy (OCMD) [MIM:613587] | ||||
| VAR_068350 | Occult macular dystrophy (OCMD) [MIM:613587] | ||||
| rs267607018 | Pathogenic | 10,611,220(-) | GCGAA(C/T)GGCTG | reference, missense | |
| rs377269054 | Likely pathogenic | 10,622,967(+) | AGAGC(A/G)CACCC | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv824532 | CNV | gain | 20364138 |
| nsv610268 | CNV | loss | 21841781 |
| nsv610267 | CNV | gain | 21841781 |
| nsv527445 | CNV | loss | 19592680 |
| nsv523113 | CNV | loss | 19592680 |
| nsv1129295 | CNV | insertion | 24896259 |
| nsv1030934 | CNV | gain | 25217958 |
| nsv1025557 | CNV | gain | 25217958 |
| esv997256 | CNV | insertion | 20482838 |
| esv2669109 | CNV | deletion | 23128226 |
| esv1658461 | CNV | insertion | 17803354 |
| dgv7010n100 | CNV | loss | 25217958 |
Residual Variation Intolerance Score:
99.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
29.90;
99.90% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RP1L1 Gene
Disorders for RP1L1 Gene
(5) MalaCards diseases for RP1L1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| occult macular dystrophy |
|
|
| retinitis pigmentosa 1 |
|
|
| presbyopia |
|
|
| eye accommodation disease |
|
|
| retinitis pigmentosa |
|
|
Search RP1L1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
RP1L1_HUMAN- Occult macular dystrophy (OCMD) [MIM:613587]: An inherited macular dystrophy characterized by progressive loss of macular function but normal ophthalmoscopic appearance. It is typically characterized by a central cone dysfunction leading to a loss of vision despite normal ophthalmoscopic appearance, normal fluorescein angiography, and normal full-field electroretinogram (ERGs), but the amplitudes of the focal macular ERGs and multifocal ERGs are significantly reduced at the central retina. {ECO:0000269 PubMed:20826268, ECO:0000269 PubMed:22605915}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for RP1L1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- RP1L1
No data available for Genatlas for RP1L1 Gene
Publications for RP1L1 Gene
- Identification and characterization of the retinitis pigmentosa 1- like1 gene (rp1l1): a novel candidate for retinal degenerations. (PMID: 12634863) Conte I. … Banfi S. (Eur. J. Hum. Genet. 2003) 2 3 4 22 64
- Characterization of RP1L1, a highly polymorphic paralog of the retinitis pigmentosa 1 (RP1) gene. (PMID: 12724644) Bowne S.J. … Sullivan L.S. (Mol. Vis. 2003) 3 4 22 64
- Dominant mutations in RP1L1 are responsible for occult macular dystrophy. (PMID: 20826268) Akahori M. … Iwata T. (Am. J. Hum. Genet. 2010) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Transcriptional regulatory network of SOX4 during myoblast differentiation. (PMID: 25969425) Jang S.M. … Choi K.H. (Biochem. Biophys. Res. Commun. 2015) 3 64
Products for RP1L1 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- OriGene qPCR primer pairs for RP1L1
- OriGene CRISPR knockouts for RP1L1
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- Novus Biologicals
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- ViGene Biosciences adenoviral particle packaged cDNA for RP1L1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for RP1L1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RP1L1 gene
- Search ViGene Biosciences for RP1L1
- Horizon Cell Lines for RP1L1
- Cyagen custom Knockout/knockin (KOKI) mouse models for RP1L1
- VectorBuilder custom plasmid, inducible vectors for RP1L1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RP1L1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RP1L1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab