Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ROPN1 Gene

protein-coding   GIFtS: 48
GCID: GC03M123636

Rhophilin Associated Tail Protein 1

(Previous names: ropporin, rhophilin associated protein 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Rhophilin Associated Tail Protein 11 2     ODF62 5
Cancer/Testis Antigen 911 2 3     RHPNAP12
Ropporin, Rhophilin Associated Protein 11 2     Outer Dense Fiber Of Sperm Tails 62
Rhophilin-Associated Protein 1A2 3     ropporin2
CT912 3     ropporin-1A2
ROPN1A2 3     

External Ids:    HGNC: 176921   Entrez Gene: 547632   Ensembl: ENSG000000653717   OMIM: 6117575   UniProtKB: Q9HAT03   

Export aliases for ROPN1 gene to outside databases

Previous GC identifers: GC03M124969 GC03M125008 GC03M125170 GC03M121061


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ROPN1 Gene: 
ROPN1 (rhophilin associated tail protein 1) is a protein-coding gene. Diseases associated with ROPN1 include multiple myeloma, and myeloma. GO annotations related to this gene include cAMP-dependent protein kinase regulator activity. An important paralog of this gene is ROPN1L.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ROPN1 gene promoter:
         TBP   AP-1   MyoD   STAT5A   Evi-1   GATA-2   MEF-2A   CREB   aMEF-2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidROPN1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ROPN1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ROPN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21.1   Ensembl cytogenetic band:  3q21.1   HGNC cytogenetic band: 3q21.1

ROPN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ROPN1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M123636:  view genomic region     (about GC identifiers)

Start:
123,687,368 bp from pter      End:
123,711,025 bp from pter
Size:
23,658 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ROP1A_HUMAN, Q9HAT0 (See protein sequence)
Recommended Name: Ropporin-1A  
Size: 212 amino acids; 23893 Da
Subunit: Homodimer. Interacts with AKAP3 and RHPN1 (By similarity). May interact with SPA17
Subcellular location: Note=In the sperm tail, found in the principal piece and in the cytoplasmic droplet located
at the distal end of the midpiece. Inner surface of the fibrous sheath (By similarity)
Developmental stage: Expressed in fetal liver
Miscellaneous: 'Ropporin' comes from the Japanese word 'oppo' which means 'tail'
Secondary accessions: D3DN99 Q9UF38
Alternative splicing: 2 isoforms:  Q9HAT0-1   Q9HAT0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ROPN1: NX_Q9HAT0

Explore proteomics data for ROPN1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9HAT0

  • ROPN1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ROPN1 Protein Expression
    REFSEQ proteins: NP_060048.2  
    ENSEMBL proteins: 
     ENSP00000184183   ENSP00000385919   ENSP00000417067   ENSP00000420310   ENSP00000418931  
     ENSP00000420590   ENSP00000420567   ENSP00000417379   ENSP00000419205  

    Human Recombinant Protein Products for ROPN1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ROPN1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ROPN1
    GenScript Custom Purified and Recombinant Proteins Services for ROPN1
    Novus Biologicals ROPN1 Protein
    Novus Biologicals ROPN1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ROPN1 


    ROPN1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ROPN1
    GenScript Custom Superior Antibodies Services for ROPN1
    Novus Biologicals ROPN1 Antibodies
    Abcam antibodies for ROPN1
    Cloud-Clone Corp. Antibodies for ROPN1 
    Search ThermoFisher Antibodies for ROPN1
    LSBio Antibodies in human, mouse, rat for ROPN1 

    Assay Products for ROPN1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ROPN1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ROPN1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ROPN1 
    Cloud-Clone Corp. CLIAs for ROPN1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR003117 cAMP_dep_PK_reg_su_I/II_a/b

    Graphical View of Domain Structure for InterPro Entry Q9HAT0

    ProtoNet protein and cluster: Q9HAT0

    UniProtKB/Swiss-Prot: ROP1A_HUMAN, Q9HAT0
    Domain: The RIIa domain mediates interaction with AKAP3 (By similarity)
    Similarity: Belongs to the ropporin family
    Similarity: Contains 1 RIIa domain


    ROPN1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008603cAMP-dependent protein kinase regulator activity IEA--
         
    ROPN1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ROPN1:
     Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ROPN1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ROPN1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ROPN1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ROPN1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ROPN1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate ROPN1:
    hsa-miR-141* hsa-miR-3647-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ROPN1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ROPN1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ROPN1
    Sirion Biotech Customized adenovirus for overexpression of ROPN1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ROPN1 (see all 6)
    OriGene ORF clones in mouse, rat for ROPN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ROPN1 (NM_017578)
    Sino Biological Human cDNA Clone for ROPN1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ROPN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ROPN1
    Sirion Biotech Customized lentivirus for stable overexpression of ROPN1 
                         Customized lentivirus expression plasmids for stable overexpression of ROPN1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ROPN1
    Search LifeMap BioReagents cell lines for ROPN1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ROPN1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ROPN1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ROPN1 (Q9HAT03 ENSP000001841834) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AKAP3O759693, ENSP000002288504I2D: score=2 STRING: ENSP00000228850
    RHPN1Q8TCX53, ENSP000002890134I2D: score=1 STRING: ENSP00000289013
    SPA17Q155063, ENSP000002271354I2D: score=2 STRING: ENSP00000227135
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--

    ROPN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ROPN1 (ROP1A)

    Search CenterWatch for drugs/clinical trials and news about ROPN1 / ROP1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ROPN1 gene: 
    NM_017578.2  

    Unigene Cluster for ROPN1:

    Rhophilin associated tail protein 1
    Hs.733553  [show with all ESTs]
    Unigene Representative Sequence: BC111005
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000184183(uc003eha.3) ENST00000405845 ENST00000487124 ENST00000467907
    ENST00000460743 ENST00000496145 ENST00000459660(uc003ehb.2) ENST00000479867(uc003ehc.2)
    ENST00000495093 ENST00000484329
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ROPN1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate ROPN1:
    hsa-miR-141* hsa-miR-3647-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ROPN1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ROPN1
    Clone
    Products:
         
    OriGene clones in human, mouse for ROPN1 (see all 6)
    OriGene ORF clones in mouse, rat for ROPN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ROPN1 (NM_017578)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ROPN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ROPN1
    Sirion Biotech Customized lentivirus for stable overexpression of ROPN1 
                         Customized lentivirus expression plasmids for stable overexpression of ROPN1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ROPN1
    OriGene qSTAR qPCR primer pairs in human, mouse for ROPN1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ROPN1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ROPN1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ROPN1

    Additional mRNA sequence: 

    AF303889.2 AK310283.1 BC111005.1 BC132744.1 BC132746.1 

    4 DOTS entries:

    DT.441723  DT.97822037  DT.120892359  DT.95169569 

    23 AceView cDNA sequences:

    BI831090 BM554135 BC015413 AF231410 BI828359 AL037365 BG704322 BI830464 
    BM552738 BG034740 BG719580 BG719672 BI826006 BG771571 BG719581 BM559594 
    CB989847 AA506126 AI016755 BE894254 BI560054 BI828708 CD708847 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ROPN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAACAGGAAG
    ROPN1 Expression
    About this image


    See ROPN1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ROPN1

    SOURCE GeneReport for Unigene cluster: Hs.733553

    UniProtKB/Swiss-Prot: ROP1A_HUMAN, Q9HAT0
    Tissue specificity: Testis specific in adult. Overexpressed in hematologic tumor cells

        SABiosciences Custom PCR Arrays for ROPN1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ROPN1
    OriGene qSTAR qPCR primer pairs in human, mouse for ROPN1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ROPN1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ROPN1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ROPN1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ROPN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ROPN1 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ropn11 , 5 ropporin, rhophilin associated protein 11, 5 85.53(n)1
    83.49(a)1
      16 (24.44 cM)5
    763781  NM_030744.21  NP_109669.11 
     346499215 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    76(a)
    1 → many
    1(78869602-78919632)
    zebrafish
    (Danio rerio)
    Actinopterygii ropn1l6
    ropporin 1-like
    42(a)
    1 → many
    24(22629623-22639025)


    ENSEMBL Gene Tree for ROPN1 (if available)
    TreeFam Gene Tree for ROPN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ROPN1 gene
    ROPN1L2  ROPN1B2  
    2 SIMAP similar genes for ROPN1 using alignment to 4 protein entries:     ROP1A_HUMAN (see all proteins):
    ROPN1B    ROPN1L

    ROPN1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/444 SNPs in ROPN1 are shown (see all 444)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1822070081,2
    --123687548(+) CTAACC/GTCAAT 1 -- int10--------
    rs1875612781,2
    --123687593(+) AGCACA/GGTACC 1 -- int10--------
    rs1920049681,2
    --123687634(+) TCAATG/TGACCA 1 -- int10--------
    rs1835552161,2
    --123687732(+) AGTCTA/GGCTTT 1 -- int10--------
    rs1140291301,2
    C,F--123687876(+) TCATAT/CGTTTA 1 -- spd11Minor allele frequency- C:0.03WA 118
    rs3774028361,2
    C--123687960(+) GTACAA/GTCATC 1 -- ut310--------
    rs178424751,2
    C,F,H--123688032(+) TGGGTA/GAAGTC 2 F syn116Minor allele frequency- G:0.05NA NS EA CSA WA 6004
    rs2007236041,2
    --123688080(+) GGAAAA/GAGGTA 1 -- int10--------
    rs1996492461,2
    --123688081(+) GAAAAA/GGGTAT 1 -- int10--------
    rs2018761151,2
    C--123688083(+) AAAAGG/ATATAT 1 -- int11Minor allele frequency- A:0.00EU 1319

    HapMap Linkage Disequilibrium report for ROPN1 (123687368 - 123711025 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ROPN1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv877397CNV Gain21882294
    nsv460837CNV Gain19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ROPN1
    DNA2.0 Custom Variant and Variant Library Synthesis for ROPN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611757    OMIM disorders: --

    2 diseases for ROPN1:    About MalaCards
    multiple myeloma    myeloma


    ROPN1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ROPN1
    Human Genome Epidemiology (HuGE) Navigator: ROPN1 (1 document)

    Export disorders for ROPN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ROPN1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ROPN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A yeast two-hybrid system using Sp17 identified ropporin as a novel cancer-testis antigen in hematologic malignancies. (PubMed id 17551920)1, 2, 9 Li Z.... Lim S.H. (2007)
    2. Kalirin: a novel genetic risk factor for ischemic str oke. (PubMed id 20107840)1, 4, 9 Krug T....Oliveira S.A. (2010)
    3. Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella. (PubMed id 10591629)1, 3 Fujita A....Narumiya S. (2000)
    4. Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA. (PubMed id 11278869)1, 9 Carr D.W....Narumiya S. (2001)
    5. Loss of ASP but not ROPN1 reduces mammalian ciliary mo tility. (PubMed id 22021175)1 Fiedler S.E....Carr D.W. (2012)
    6. CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath. (PubMed id 21240291)1 Li Y.F....Herr J.C. (2011)
    7. Cancer testis antigen, ropporin, is a potential targe t for multiple myeloma immunotherapy. (PubMed id 21654522)1 Chiriva-Internati M....Cobos E. (2011)
    8. Functional expression of ropporin in human testis and ejaculated spermatozoa. (PubMed id 20705794)1 Chen J....Cai Z. (2011)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54763 HGNC: 17692 AceView: LOC152015 Ensembl:ENSG00000065371 euGenes: HUgn54763
    ECgene: ROPN1 H-InvDB: ROPN1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ROPN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ROPN1 gene:
    Search GeneIP for patents involving ROPN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ROPN1  
     OriGene qPCR primer pairs and template standards for ROPN1   OriGene Protein Over-expression Lysate for ROPN1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ROPN1  
     OriGene qSTAR qPCR primer pairs in human, mouse for ROPN1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ROPN1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ROPN1   OriGene Custom Protein Services for ROPN1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ROPN1
     QIAGEN SeqTarget long-range PCR primers for resequencing ROPN1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ROPN1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ROPN1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ROPN1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ROPN1
     GenScript Custom Purified and Recombinant Proteins Services for ROPN1 GenScript cDNA clones with any tag delivered in your preferred vector for ROPN1
     GenScript Custom Assay Services for ROPN1 GenScript Custom Superior Antibodies Services for ROPN1
     GenScript Custom overexpressing Cell Line Services for ROPN1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ROPN1 promoter
     Search Chromatin IP Primers for ROPN1
     RT2 qPCR Primer Assay in human, mouse, rat ROPN1
     GNC Network for ROPN1
     SABiosciences Custom PCR Arrays for ROPN1
     Search Tocris compounds for ROPN1 (ROP1A)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ROPN1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ROPN1 antibodies
     ROPN1 proteins
     ROPN1 lysates
     Antibodies for ROPN1
     See all of Abcam's Antibodies, Kits and Proteins for ROPN1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ROPN1
     Antibodies for ROPN1
     ELISAs for ROPN1
     CLIAs for ROPN1
     Search LifeMap BioReagents cell lines for ROPN1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ROPN1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ROPN1
     SwitchGear Promoter luciferase reporter plasmids for ROPN1
     Search ThermoFisher Antibodies for ROPN1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ROPN1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ROPN1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ROPN1
    Customized:
     lentivirus for stable overexpression of ROPN1
     lentivirus expression plasmids for stable overexpression of ROPN1
     adenovirus for overexpression of ROPN1
     LSBio Antibodies in human, mouse, rat for ROPN1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ROPN1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4