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ROGDI Gene

protein-coding   GIFtS: 53
GCID: GC16M004846

Rogdi Homolog (Drosophila)

  See ROGDI-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Rogdi Homolog (Drosophila)1 2
KTZS2 5
Leucine Zipper Domain Protein2
Protein Rogdi Homolog2

External Ids:    HGNC: 294781   Entrez Gene: 796412   Ensembl: ENSG000000678367   OMIM: 6145745   UniProtKB: Q9GZN73   

Export aliases for ROGDI gene to outside databases

Previous GC identifer: GC16M004787


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ROGDI Gene:
This gene encodes a protein of unknown function. Loss-of-function mutation in this gene cause Kohlschutter-Tonz
syndrome. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Mar 2012)

GeneCards Summary for ROGDI Gene:
ROGDI (rogdi homolog (Drosophila)) is a protein-coding gene. Diseases associated with ROGDI include kohlschutter tonz syndrome, and focal epilepsy.

UniProtKB/Swiss-Prot: ROGDI_HUMAN, Q9GZN7
Function: May act as a positive regulator of cell proliferation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NT_010393.17  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ROGDI gene promoter:
         CBF-B   CBF-A   Tal-1   MyoD   Hand1   CP1A   NF-Y   CBF(2)   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidROGDI promoter sequence
   Search Chromatin IP Primers for ROGDI

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ROGDI


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

ROGDI Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ROGDI gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M004846:  view genomic region     (about GC identifiers)

Start:
4,846,969 bp from pter      End:
4,852,951 bp from pter
Size:
5,983 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ROGDI_HUMAN, Q9GZN7 (See protein sequence)
Recommended Name: Protein rogdi homolog  
Size: 287 amino acids; 32254 Da
Secondary accessions: Q6IA00

Explore the universe of human proteins at neXtProt for ROGDI: NX_Q9GZN7

Explore proteomics data for ROGDI at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ROGDI Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078865.1  
    ENSEMBL proteins: 
     ENSP00000322832   ENSP00000465970   ENSP00000468343   ENSP00000466529   ENSP00000468334  
     ENSP00000465076   ENSP00000467509   ENSP00000467459   ENSP00000464699  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR019386 Rogdi_leu_zipper-containing
     IPR028241 RAVE2/Rogdi

    Graphical View of Domain Structure for InterPro Entry Q9GZN7

    ProtoNet protein and cluster: Q9GZN7

    UniProtKB/Swiss-Prot: ROGDI_HUMAN, Q9GZN7
    Similarity: Belongs to the rogdi family


    Find genes that share domains with ROGDI           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ROGDI_HUMAN, Q9GZN7
    Function: May act as a positive regulator of cell proliferation (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for ROGDI:

     Increased gamma-H2AX phosphory 

    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target ROGDI:
    hsa-mir-26b-5p (MIRT029066), hsa-mir-16-5p (MIRT051133)

    Block miRNA regulation of human, mouse, rat ROGDI using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate ROGDI:
    hsa-miR-206 hsa-miR-613 hsa-miR-1 hsa-miR-299-3p
    SwitchGear 3'UTR luciferase reporter plasmidROGDI 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ROGDI_HUMAN, Q9GZN7: Nucleus envelope
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--
    GO:0005635nuclear envelope IEA--

    Find genes that share ontologies with ROGDI           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ROGDI
    Interactions:

        Search GeneGlobe Interaction Network for ROGDI

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for ROGDI (Q9GZN72, 3 ENSP000003228324) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS6Q7L5N12, 3MINT-64595 I2D: score=5 
    KIAA1377Q9P2H02, 3MINT-64596 I2D: score=5 
    CALM1P621583I2D: score=3 
    CALM2P621583I2D: score=3 
    CALM3P621583I2D: score=3 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008284positive regulation of cell proliferation IEA--
    GO:0030097hemopoiesis IEA--

    Find genes that share ontologies with ROGDI           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ROGDI



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ROGDI gene: 
    NM_024589.2  

    Unigene Cluster for ROGDI:

    Rogdi homolog (Drosophila)
    Hs.459795  [show with all ESTs]
    Unigene Representative Sequence: AK054707
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322048(uc002cxu.3 uc010bub.1 uc002cxv.3 uc002cxw.3 uc010uxu.2)
    ENST00000591292 ENST00000587843 ENST00000587377 ENST00000588201 ENST00000592019
    ENST00000586504 ENST00000591392 ENST00000587711 ENST00000586153 ENST00000586336
    ENST00000589543 ENST00000585653 ENST00000585871 ENST00000590198 ENST00000592112

    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate ROGDI:
    hsa-miR-206 hsa-miR-613 hsa-miR-1 hsa-miR-299-3p
    SwitchGear 3'UTR luciferase reporter plasmidROGDI 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK026039.1 AK054707.1 AK098348.1 AK296334.1 AL136675.1 BC012901.2 BC113944.1 CR457355.1 
    CR533547.1 NR_046480.1 

    10 DOTS entries:

    DT.451734  DT.92443741  DT.95343377  DT.91882634  DT.95343385  DT.92443739  DT.120680375  DT.100796647 
    DT.86820161  DT.95343373 

    Selected AceView cDNA sequences (see all 521):

    AA887264 BI518431 AI401496 BP364820 AI478491 BU193709 AA341472 CR608501 
    BE855579 CB139232 BP430007 BE503523 BQ068325 AA453238 R68334 BM696417 
    BM671209 CA429512 AI687916 AA346657 AA348753 BM475320 AA156958 BQ720854 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ROGDI (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b · 12c
    SP1:                          -     -           -           -                                         -                                 
    SP2:                          -     -           -     -     -                                         -                                 
    SP3:                                                                                                  -                                 
    SP4:                                            -     -     -                                                                           
    SP5:                                                                                                                                    


    ECgene alternative splicing isoforms for ROGDI

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ROGDI expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTCGGGGG
    ROGDI Expression
    About this image


    ROGDI expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
    ROGDI Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ROGDI Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.459795

    UniProtKB/Swiss-Prot: ROGDI_HUMAN, Q9GZN7
    Tissue specificity: Widely expressed with highest levels in spinal cord, brain, heart and bone marrow. Also
    expressed in fetal brain and liver

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ROGDI gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rogdi1 , 5 rogdi homolog (Drosophila)1, 5 87.97(n)1
    94.95(a)1
      16 (2.49 cM)5
    660491  NM_133185.21  NP_573448.21 
     50087305 
    chicken
    (Gallus gallus)
    Aves ROGDI1 rogdi homolog (Drosophila) 74.37(n)
    82.31(a)
      426990  XM_424594.4  XP_424594.3 
    lizard
    (Anolis carolinensis)
    Reptilia ROGDI6
    rogdi homolog (Drosophila)
    81(a)
    1 ↔ 1
    GL343263.1(1329016-1342302)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.70552 Transcribed sequence with moderate similarity to protein more 79.45(n)    142034820 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj32e072 wufj32e07 75.45(n)   335642  BC045418.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta rogdi1 rogdi 54.36(n)
    44.81(a)
      39917  NM_168717.2  NP_730244.1 
    worm
    (Caenorhabditis elegans)
    Secernentea H14A12.36
    Protein H14A12.3 (H14A12.3) mRNA, complete cds
    23(a)
    1 ↔ 1
    III(7463838-7465238) WBGene00019196


    ENSEMBL Gene Tree for ROGDI (if available)
    TreeFam Gene Tree for ROGDI (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ROGDI (see all 319)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1454365481,2
    --4782913(+) ACTTTC/GGGAGG 2 -- ds50010--------
    rs1476821941,2
    --4782940(+) ACGAGA/GTCAGG 2 -- ds50010--------
    rs564000141,2
    C--4782969(+) TTAACA/GTGGTG 2 -- ds50012Minor allele frequency- G:0.25NA 4
    rs1810110731,2
    --4783073(+) CACTTG/TAACCC 2 -- ds50010--------
    rs1445882651,2
    --4783189(+) AGTCCC/TAGGTA 2 -- ds50010--------
    rs791965611,2
    C,F--4783255(+) AGTAGG/ATTCTG 2 -- ds50011Minor allele frequency- A:0.07WA 118
    rs1851656201,2
    --4783279(+) CATGGC/GACAGG 2 -- ds50010--------
    rs99327061,2
    C,F,A,H--4783290(+) GAACGG/CGGAAG 2 -- ds50019Minor allele frequency- C:0.49WA NA CSA EA 370
    rs1457169401,2
    C--4783305(+) GCTCCA/GGGAAT 2 -- ds50010--------
    rs1491073931,2
    --4783342(+) CATGGA/CCACTG 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for ROGDI (4846969 - 4852951 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ROGDI:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422516CNV Deletion17116639
    nsv905251CNV Loss21882294
    nsv905248CNV Loss21882294
    nsv905250CNV Loss21882294
    dgv2589n71CNV Loss21882294
    esv26756CNV Gain+Loss19812545

    Human Gene Mutation Database (HGMD): ROGDI
    Locus Specific Mutation Databases (LSDB): ROGDI

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ROGDI
    DNA2.0 Custom Variant and Variant Library Synthesis for ROGDI

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614574   
    OMIM disorders: 226750  
    UniProtKB/Swiss-Prot: ROGDI_HUMAN, Q9GZN7
  • Kohlschuetter-Toenz syndrome (KTZS) [MIM:226750]: An autosomal recessive disorder characterized by severe
    global developmental delay, early-onset intractable seizures, spasticity, and amelogenesis imperfecta affecting
    both primary and secondary teeth and causing yellow or brown discoloration of the teeth. Although the phenotype
    is consistent, there is variability. Intellectual disability is related to the severity of seizures, and the
    disorder can thus be considered an epileptic encephalopathy. Some infants show normal development until seizure
    onset, whereas others are delayed from birth. The most severely affected individuals have profound mental
    retardation, never acquire speech, and become bedridden early in life. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 2 diseases for ROGDI:    
    About MalaCards
    kohlschutter tonz syndrome    focal epilepsy

    2 diseases from the University of Copenhagen DISEASES database for ROGDI:
    Amelogenesis imperfecta     Focal epilepsy

    Find genes that share disorders with ROGDI           About GenesLikeMe


    Export disorders for ROGDI gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ROGDI gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ROGDI)
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    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Mutations in ROGDI cause Kohlschutter-Tonz syndrome. (PubMed id 22424600)1, 2 Schossig A.... Zschocke J. (Am. J. Hum. Genet. 2012)
    3. A nonsense mutation in the human homolog of Drosophila rogdi causes Kohlschutter-Tonz syndrome. (PubMed id 22482807)1, 2 Mory A....Gershoni-Baruch R. (Am. J. Hum. Genet. 2012)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. KohlschA1tter-TAPnz syndrome: mutations in ROGDI and evidence of genetic heterogeneity. (PubMed id 23086778)1 Tucci A....Houlden H. (Hum. Mutat. 2013)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)1 Camargo L.M....Brandon N.J. (Mol. Psychiatry 2007)
    8. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    9. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79641 HGNC: 29478 AceView: FLJ22386andN-PAC Ensembl:ENSG00000067836 euGenes: HUgn79641
    ECgene: ROGDI H-InvDB: ROGDI

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ROGDI Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ROGDI gene:
    Search GeneIP for patents involving ROGDI

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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