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Aliases for RNY1 Gene

Subcategory (RNA class) for RNY1 Gene

Y RNA

Quality Score for this RNA gene is

3

Aliases for RNY1 Gene

  • RNA, Ro-Associated Y1 2 3
  • RNA, Y1 Small Cytoplasmic (Associated With Ro Protein) 2 3
  • Y1 3 6
  • HY1 3

External Ids for RNY1 Gene

ORGUL Members for RNY1 Gene

Previous GeneCards Identifiers for RNY1 Gene

  • GC07U990082
  • GC07M148316
  • GC07M148685
  • GC07M142763

Summaries for RNY1 Gene

Entrez Gene Summary for RNY1 Gene

  • Y RNAs are small noncoding RNAs that were originally identified as the RNA component of soluble ribonucleoproteins (RNPs) termed Ro RNPs. Ro RNPs are detected by autoimmune sera of patients suffering from rheumatic diseases, such as from systemic lupus erythematosus (MIM 152700) and Sjogren syndrome (MIM 270200). Ro RNPs consist of a Y RNA that is associated with the autoimmune antigen proteins Ro60 (TROVE2; MIM 600063) and La (SSB; MIM 109090), as well as other proteins. Four human Y RNAs have been identified: Y1, Y3 (RNY3; MIM 601822), Y4 (RNY4; MIM 601823), and Y5 (RNY5; MIM 601824). (Y2 is a truncated form of Y1.) Y RNAs are transcribed by RNA polymerase III and range in size from 83 to 112 nucleotides. They appear to have a functional role in chromosomal DNA replication (Christov et al., 2006 [PubMed 16943439]).[supplied by OMIM, Apr 2009]

GeneCards Summary for RNY1 Gene

RNY1 (RNA, Ro-Associated Y1) is an RNA Gene, and is affiliated with the Y RNA class. Diseases associated with RNY1 include sjogren's syndrome and rheumatic disease.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNY1 Gene

Genomics for RNY1 Gene

Regulatory Elements for RNY1 Gene

Genomic Location for RNY1 Gene

Start:
148,987,136 bp from pter
End:
148,987,248 bp from pter
Size:
113 bases
Orientation:
Minus strand

Genomic View for RNY1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNY1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNY1 Gene

Proteins for RNY1 Gene

Post-translational modifications for RNY1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNY1 Gene

Domains for RNY1 Gene

Gene Families for RNY1 Gene

HGNC:
  • RNY :Y RNAs (Ro-associated)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNY1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNY1 Gene

Function for RNY1 Gene

Molecular function for RNY1 Gene

GENATLAS Biochemistry: small cytoplasmic ribonucleoprotein RY1,component of Ro ribonucleoprotein

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RNY1 Gene

Localization for RNY1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNY1 Gene

Pathways for RNY1 Gene

SuperPathways for RNY1 Gene

No Data Available

Interacting Proteins for RNY1 Gene

Gene Ontology (GO) - Biological Process for RNY1 Gene

None

No data available for Pathways by source for RNY1 Gene

Compounds for RNY1 Gene

(1) Novoseek inferred chemical compound relationships for RNY1 Gene

Compound -log(P) Hits PubMed IDs
calcium 0 1
genes like me logo Genes that share compounds with RNY1: view

Transcripts for RNY1 Gene

mRNA/cDNA for RNY1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNY1 Gene

No ASD Table

Relevant External Links for RNY1 Gene

GeneLoc Exon Structure for
RNY1
ECgene alternative splicing isoforms for
RNY1

Expression for RNY1 Gene

mRNA expression in normal human tissues for RNY1 Gene

genes like me logo Genes that share expressions with RNY1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for RNY1 Gene

Orthologs for RNY1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNY1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia Y_RNA 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia Y_RNA 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rny1 16
Rny1 36
  • 98 (a)
OneToOne
Species with no ortholog for RNY1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNY1 Gene

ENSEMBL:
Gene Tree for RNY1 (if available)
TreeFam:
Gene Tree for RNY1 (if available)

Paralogs for RNY1 Gene

No data available for Paralogs for RNY1 Gene

Variants for RNY1 Gene

Sequence variations from dbSNP and Humsavar for RNY1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2616856 -- 148,987,255(-) GGAGG(A/G)CTTAT upstream-variant-2KB
rs2616857 -- 148,986,705(-) GCCTC(C/G)TGGGT downstream-variant-500B
rs12671106 -- 148,987,153(+) AAGTG(C/T)AGTAG nc-transcript-variant
rs35954058 -- 148,987,257(+) AAGTC(C/T)TCCTA upstream-variant-2KB
rs55754821 -- 148,987,259(+) GTCCT(C/G)CTACT upstream-variant-2KB

Relevant External Links for RNY1 Gene

HapMap Linkage Disequilibrium report
RNY1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RNY1 Gene

Disorders for RNY1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (3) Diseases for RNY1 Gene including...

Search for RNY1 Gene in MalaCards »
genes like me logo Genes that share disorders with RNY1: view

No data available for UniProtKB/Swiss-Prot for RNY1 Gene

Publications for RNY1 Gene

  1. Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome. (PMID: 6187471) Wolin S.L. … Steitz J.A. (Cell 1983) 2 3
  2. Gene encoding human Ro-associated autoantigen Y5 RNA. (PMID: 8836182) Maraia R. … Green E.D. (Nucleic Acids Res. 1996) 3
  3. Functional requirement of noncoding Y RNAs for human chromosomal DNA replication. (PMID: 16943439) Christov C.P. … Krude T. (Mol. Cell. Biol. 2006) 3
  4. The P genes of human parainfluenza virus type 1 clinical isolates are polycistronic and microheterogeneous. (PMID: 1318610) Power U.F. … Portner A. (Virology 1992) 23
  5. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. (PMID: 2153286) Fuhlendorff J. … Schwartz T.W. (Proc. Natl. Acad. Sci. U.S.A. 1990) 23

Products for RNY1 Gene

Sources for RNY1 Gene

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